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The map label for this gene is secY [H]

Identifier: 119899686

GI number: 119899686

Start: 3732238

End: 3733563

Strand: Reverse

Name: secY [H]

Synonym: azo3397

Alternate gene names: 119899686

Gene position: 3733563-3732238 (Counterclockwise)

Preceding gene: 119899687

Following gene: 119899685

Centisome position: 85.32

GC content: 60.11

Gene sequence:

>1326_bases
GTGGCAAATCCGTCAGCCGCTCTCGGGAATCCGGGCAAGTTCGGTGACCTCAAGCGCCGCCTGCTGTTCCTGGTCGGCGC
CCTGATCGTCTATCGAATCGGTGCGCATATCCCGGTGCCCGGTATCGACCCTGCCCGTCTTGCGGAGCTGTTCCAGTCGC
AGGCGGGTGGGATCCTCGGCGTGTTCAACCTCTTTTCCGGCGGGGCGTTGTCGCGGTTCACGATCTTTGCGCTCGGGATC
ATGCCGTACATCTCGGCGTCGATCATCATGCAGTTGATGACCGTCGCAGTGCCTCAGCTGGAGGCGCTGAAGAAGGAAGG
CGAAGCCGGTCGGCGGAAGATCACGCAGTACACCCGTTACGGGACGCTCGTGTTGGCGGTGGCGCAATCGCTTGGTATCG
CAATTGCGCTGGAAGGGCAGGCGGGTCTGGTGCTCGATCCGGGGCTGATGTTCCGCTTCGTTACGCTGGCGACGCTGGTG
ACCGGAACCATGTTCCTGATGTGGCTGGGCGAGCAGATCACGGAGCGCGGTGTTGGCAACGGGATCTCCATCATCATCTT
CGCCGGTATTGCGGCCGGATTGCCCAGTTCCATCGGTGGGCTGTTCGAACTCGTACGCACTGGCGCGATGCATCCTTTCA
CCGCATTGCTGATCTGCGTATTGGTGGTGTTGGTCACCGGCTTCGTGGTGTTTGTGGAACGGGGGCAGCGGAAGATCCTG
GTCAACTACGCCAAGCGCCAGGTCGGCAACAAGATTTATGGTGGCCAAAGCTCCCATCTGCCGTTGAAGCTGAACATGGC
TGGTGTGATTCCGCCGATCTTCGCGTCCAGCATCATCCTGTTCCCGGCAACCTTGGGGCAGTGGTTCGGCAGTTCCGAGG
GCTTGTACTGGCTGAGGGATCTCGCCTCCACGCTGTCGCCTGGTCAACCGGTGTACGTGTTGTTGTATGCGCTGGCGATT
GTCTTCTTCTGCTTCTTCTATACCGCGTTGGTGTTCAACGCGCGGGAGACGGCGGACAACCTGAAGAAGAGCGGGGCGTT
CGTGCCCGGGATTCGCCCGGGGGATCAGACGGCGAGGTACATCGACAAGATTCTCGTGCGGCTGACGCTGGCCGGAGCGG
TGTACATCACCCTGGTTTGTCTGCTTCCGGAGTTTCTGATCCTCAAGTGGAATGTTCCTTTCTACTTCGGCGGAACTTCG
CTGCTGATTATCGTCGTGGTGACGATGGACTTCATGGCCCAGGTTCAGGCCTACGTGATGTCGCACCAGTACGAGAGTCT
GCTGAAGAAGGCGAACTTCAAGGGAGCGGGTCTCCCGACCAGGTGA

Upstream 100 bases:

>100_bases
GCAAGAAGGTCGTGCTGCGCGGCATCGCTGCTACTGCTGGCGCGCGCGCCGCGATCGAAGCTGCCGGCGGCAGCTGCGGC
GAGTAAGTCAGGACCGGGTC

Downstream 100 bases:

>100_bases
TTCATGGCCAAGGAAGACGTAATTGAAATGCAGGGGGAGGTTACCGAGAACCTTCCCAATGCAACCTTCAGGGTAAAGCT
CGAGAACGGGCACATGGTTC

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MANPSAALGNPGKFGDLKRRLLFLVGALIVYRIGAHIPVPGIDPARLAELFQSQAGGILGVFNLFSGGALSRFTIFALGI
MPYISASIIMQLMTVAVPQLEALKKEGEAGRRKITQYTRYGTLVLAVAQSLGIAIALEGQAGLVLDPGLMFRFVTLATLV
TGTMFLMWLGEQITERGVGNGISIIIFAGIAAGLPSSIGGLFELVRTGAMHPFTALLICVLVVLVTGFVVFVERGQRKIL
VNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATLGQWFGSSEGLYWLRDLASTLSPGQPVYVLLYALAI
VFFCFFYTALVFNARETADNLKKSGAFVPGIRPGDQTARYIDKILVRLTLAGAVYITLVCLLPEFLILKWNVPFYFGGTS
LLIIVVVTMDFMAQVQAYVMSHQYESLLKKANFKGAGLPTR

Sequences:

>Translated_441_residues
MANPSAALGNPGKFGDLKRRLLFLVGALIVYRIGAHIPVPGIDPARLAELFQSQAGGILGVFNLFSGGALSRFTIFALGI
MPYISASIIMQLMTVAVPQLEALKKEGEAGRRKITQYTRYGTLVLAVAQSLGIAIALEGQAGLVLDPGLMFRFVTLATLV
TGTMFLMWLGEQITERGVGNGISIIIFAGIAAGLPSSIGGLFELVRTGAMHPFTALLICVLVVLVTGFVVFVERGQRKIL
VNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATLGQWFGSSEGLYWLRDLASTLSPGQPVYVLLYALAI
VFFCFFYTALVFNARETADNLKKSGAFVPGIRPGDQTARYIDKILVRLTLAGAVYITLVCLLPEFLILKWNVPFYFGGTS
LLIIVVVTMDFMAQVQAYVMSHQYESLLKKANFKGAGLPTR
>Mature_440_residues
ANPSAALGNPGKFGDLKRRLLFLVGALIVYRIGAHIPVPGIDPARLAELFQSQAGGILGVFNLFSGGALSRFTIFALGIM
PYISASIIMQLMTVAVPQLEALKKEGEAGRRKITQYTRYGTLVLAVAQSLGIAIALEGQAGLVLDPGLMFRFVTLATLVT
GTMFLMWLGEQITERGVGNGISIIIFAGIAAGLPSSIGGLFELVRTGAMHPFTALLICVLVVLVTGFVVFVERGQRKILV
NYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATLGQWFGSSEGLYWLRDLASTLSPGQPVYVLLYALAIV
FFCFFYTALVFNARETADNLKKSGAFVPGIRPGDQTARYIDKILVRLTLAGAVYITLVCLLPEFLILKWNVPFYFGGTSL
LIIVVVTMDFMAQVQAYVMSHQYESLLKKANFKGAGLPTR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=429, Percent_Identity=69.4638694638695, Blast_Score=552, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47668; Mature: 47537

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPSAALGNPGKFGDLKRRLLFLVGALIVYRIGAHIPVPGIDPARLAELFQSQAGGILG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEE
VFNLFSGGALSRFTIFALGIMPYISASIIMQLMTVAVPQLEALKKEGEAGRRKITQYTRY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GTLVLAVAQSLGIAIALEGQAGLVLDPGLMFRFVTLATLVTGTMFLMWLGEQITERGVGN
HHHHHHHHHHCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GISIIIFAGIAAGLPSSIGGLFELVRTGAMHPFTALLICVLVVLVTGFVVFVERGQRKIL
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATLGQWFGSSEGLYWLRD
HHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LASTLSPGQPVYVLLYALAIVFFCFFYTALVFNARETADNLKKSGAFVPGIRPGDQTARY
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHH
IDKILVRLTLAGAVYITLVCLLPEFLILKWNVPFYFGGTSLLIIVVVTMDFMAQVQAYVM
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SHQYESLLKKANFKGAGLPTR
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ANPSAALGNPGKFGDLKRRLLFLVGALIVYRIGAHIPVPGIDPARLAELFQSQAGGILG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEE
VFNLFSGGALSRFTIFALGIMPYISASIIMQLMTVAVPQLEALKKEGEAGRRKITQYTRY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
GTLVLAVAQSLGIAIALEGQAGLVLDPGLMFRFVTLATLVTGTMFLMWLGEQITERGVGN
HHHHHHHHHHCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GISIIIFAGIAAGLPSSIGGLFELVRTGAMHPFTALLICVLVVLVTGFVVFVERGQRKIL
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATLGQWFGSSEGLYWLRD
HHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LASTLSPGQPVYVLLYALAIVFFCFFYTALVFNARETADNLKKSGAFVPGIRPGDQTARY
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHH
IDKILVRLTLAGAVYITLVCLLPEFLILKWNVPFYFGGTSLLIIVVVTMDFMAQVQAYVM
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SHQYESLLKKANFKGAGLPTR
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]