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The map label for this gene is galE2 [H]

Identifier: 119899678

GI number: 119899678

Start: 3727870

End: 3728883

Strand: Reverse

Name: galE2 [H]

Synonym: azo3389

Alternate gene names: 119899678

Gene position: 3728883-3727870 (Counterclockwise)

Preceding gene: 119899679

Following gene: 119899675

Centisome position: 85.21

GC content: 66.17

Gene sequence:

>1014_bases
ATGACAGTGCTGGTGACGGGTGGTGCGGGTTACATCGGGTCGCATACCGTGCTCGAGTTGCTCAACGCAGGCGAGCAGGT
TGTGGTGATCGACAACCTTTCCAATGGGTCGGAGGAGGCGTTGCGGCGCGTCGAGGCGCTCGCCGGGCGCCGCCTGGCGG
GCTTCGTCAATGCCGACGTGCGTGACGTTCAGGCCCTGGACGCGTTGTTTGCGCGCTACACGGTAAGCGCGGTGATCCAC
TTTGCGGCGTTGAAGGCGGTCGGGGAATCGGTCGCGAAGCCGCTGGCGTATTACGACAACAACGTCTGCGGGCTACTCGG
ACTGGTGGATGCCATGCGTCGCGCCGAGGTCCGGCGCCTGGTGTTCAGTTCCTCGGCAACGGTGTATGGCGATCCTGCGA
GTGTTCCTATCGTCGAGGATTTTCCGACCAGTGCGACGAACCCGTATGGGCGCACGAAGTTGATGTGCGAACAGATTCTG
GCGGATGTGGCGCATGCCGATCCGGCGTGGCGCATTGCGTTATTGCGCTACTTCAACCCGGTCGGCGCCCACCCCAGCGG
GCGGCTGGGCGAGGACCCGGCGGGGATACCCAACAACCTGATGCCCTACGTCAGCCAGGTTGCGGTCGGGCGTTTGCCGG
CGCTGCAGGTTTTCGGGGGGGATTACCCGACGCCCGATGGCACCGGGGTCCGCGACTACATCCACGTTGTCGATCTTGCG
CTGGGTCACCTCAGCGCGCTCAGGCGGCTCGACTCGCTGCCTCCGGTAGATGCGATCAACCTGGGGACCGGGTGCGGGTA
CAGTGTGCTGGAGGTCGTGGAGGCTTTCCGCAAGGCGAGCGGGCGCGCGGTGCCGTTCCGTATCGTCGACCGTCGTCCCG
GCGATGTCGCCGCGTGCTGGGCGGACACCGCGAAGGCGCGGCGCGTGCTGGGGTGGCAGGCCGAGCGGGGCATTGCTGAA
ATGTGTGCCGACGCATGGCGGTGGCAGTCCGCCAACCCGTCAGGCTACCGCTAG

Upstream 100 bases:

>100_bases
GGCGGCGTAACGCTGCCCGGGAATGAAAGAAAGGCCGGAGTTTCCGGCCTTTTTTTCGTCTGTCCGATCCGGACATGCAG
ACGACATCTGAGGACGCGTG

Downstream 100 bases:

>100_bases
CCGGTGCCTACCATTCGCGCTTGATGCGGTTGCGGTACTGGACGTCGTGCGGCAACAGCGGCTGCATCGCCTCCAGATGC
GCGCGCACTGTCTCGCCGGC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTVLVTGGAGYIGSHTVLELLNAGEQVVVIDNLSNGSEEALRRVEALAGRRLAGFVNADVRDVQALDALFARYTVSAVIH
FAALKAVGESVAKPLAYYDNNVCGLLGLVDAMRRAEVRRLVFSSSATVYGDPASVPIVEDFPTSATNPYGRTKLMCEQIL
ADVAHADPAWRIALLRYFNPVGAHPSGRLGEDPAGIPNNLMPYVSQVAVGRLPALQVFGGDYPTPDGTGVRDYIHVVDLA
LGHLSALRRLDSLPPVDAINLGTGCGYSVLEVVEAFRKASGRAVPFRIVDRRPGDVAACWADTAKARRVLGWQAERGIAE
MCADAWRWQSANPSGYR

Sequences:

>Translated_337_residues
MTVLVTGGAGYIGSHTVLELLNAGEQVVVIDNLSNGSEEALRRVEALAGRRLAGFVNADVRDVQALDALFARYTVSAVIH
FAALKAVGESVAKPLAYYDNNVCGLLGLVDAMRRAEVRRLVFSSSATVYGDPASVPIVEDFPTSATNPYGRTKLMCEQIL
ADVAHADPAWRIALLRYFNPVGAHPSGRLGEDPAGIPNNLMPYVSQVAVGRLPALQVFGGDYPTPDGTGVRDYIHVVDLA
LGHLSALRRLDSLPPVDAINLGTGCGYSVLEVVEAFRKASGRAVPFRIVDRRPGDVAACWADTAKARRVLGWQAERGIAE
MCADAWRWQSANPSGYR
>Mature_336_residues
TVLVTGGAGYIGSHTVLELLNAGEQVVVIDNLSNGSEEALRRVEALAGRRLAGFVNADVRDVQALDALFARYTVSAVIHF
AALKAVGESVAKPLAYYDNNVCGLLGLVDAMRRAEVRRLVFSSSATVYGDPASVPIVEDFPTSATNPYGRTKLMCEQILA
DVAHADPAWRIALLRYFNPVGAHPSGRLGEDPAGIPNNLMPYVSQVAVGRLPALQVFGGDYPTPDGTGVRDYIHVVDLAL
GHLSALRRLDSLPPVDAINLGTGCGYSVLEVVEAFRKASGRAVPFRIVDRRPGDVAACWADTAKARRVLGWQAERGIAEM
CADAWRWQSANPSGYR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=58.3577712609971, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=58.3577712609971, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=58.3577712609971, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI7657641, Length=271, Percent_Identity=25.0922509225092, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI42516563, Length=317, Percent_Identity=25.8675078864353, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=56.973293768546, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI48994969, Length=361, Percent_Identity=26.0387811634349, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=26.9972451790634, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=54.9132947976879, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=54.5977011494253, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17568069, Length=338, Percent_Identity=25.4437869822485, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=50.5813953488372, Blast_Score=352, Evalue=4e-98,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=56.3953488372093, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=23.1012658227848, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36142; Mature: 36010

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVTGGAGYIGSHTVLELLNAGEQVVVIDNLSNGSEEALRRVEALAGRRLAGFVNADV
CEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHCCCH
RDVQALDALFARYTVSAVIHFAALKAVGESVAKPLAYYDNNVCGLLGLVDAMRRAEVRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VFSSSATVYGDPASVPIVEDFPTSATNPYGRTKLMCEQILADVAHADPAWRIALLRYFNP
HHHCCCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
VGAHPSGRLGEDPAGIPNNLMPYVSQVAVGRLPALQVFGGDYPTPDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
LGHLSALRRLDSLPPVDAINLGTGCGYSVLEVVEAFRKASGRAVPFRIVDRRPGDVAACW
HHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEHHH
ADTAKARRVLGWQAERGIAEMCADAWRWQSANPSGYR
HHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TVLVTGGAGYIGSHTVLELLNAGEQVVVIDNLSNGSEEALRRVEALAGRRLAGFVNADV
EEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHCCCH
RDVQALDALFARYTVSAVIHFAALKAVGESVAKPLAYYDNNVCGLLGLVDAMRRAEVRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VFSSSATVYGDPASVPIVEDFPTSATNPYGRTKLMCEQILADVAHADPAWRIALLRYFNP
HHHCCCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
VGAHPSGRLGEDPAGIPNNLMPYVSQVAVGRLPALQVFGGDYPTPDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
LGHLSALRRLDSLPPVDAINLGTGCGYSVLEVVEAFRKASGRAVPFRIVDRRPGDVAACW
HHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEHHH
ADTAKARRVLGWQAERGIAEMCADAWRWQSANPSGYR
HHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]