Click here to switch to the map view.

The map label for this gene is ltrA [H]

Identifier: 119899660

GI number: 119899660

Start: 3705329

End: 3706252

Strand: Direct

Name: ltrA [H]

Synonym: azo3371

Alternate gene names: 119899660

Gene position: 3705329-3706252 (Clockwise)

Preceding gene: 119899653

Following gene: 119899661

Centisome position: 84.67

GC content: 71.0

Gene sequence:

>924_bases
ATGGAACAATTCGACGCCAATGATCTGCTGATCTTTGCCCGCGTGGCCGAAGGCGGCAGCTTCAGCCGCGCGGCCGAGCG
CCTTGGTCTGCCCAAGTCCACCGTGTCGCGCCGGATCACGCTGCTGGAAGAACGGCTGGGCGAACGGCTGATGCTGCGCA
CCACGCGCCGACTGTCGCTCACCGACTTCGGCCTGCATCTGCTGGAACACGCGCGCCAGCTCGCCGCCGAGGTCGATGCC
GTCGCCAGCCTCGCCCAGCACCGCCAGGCGCAGCCAAGCGGACGCCTGCGGGTCTCGATGCCGGCCGATTTCGCCAACCA
CCTGCTGCTGGACATGCTCTCCGCCTTCGTCGCGCTGCACCCGGCCATCAGCCTGGATCTCGACCTGTCGCCCCGGCGGG
TGGACCTGATCGGCGAGAACTTCGACCTGGCGATCCGCATCGGTGACCTGCCGGACGACGCCTCGCTCGCCGCGCGGCGC
ATCCGCAGCTTTCCGATCAGCCTGTATGCCGCCCGCGACTACCTCGCCGAACGTGGAACGCCGCGGGTGCCGGACGACCT
GATGCGGCACGAGGCGCTGCGCCTGTTCGGCCGCAGCGGCGAACCGACGCCGTGGCGTCTGCTCAACGGCGAGCAGCACT
GGGAAGGTCTGCCACCGGGCCGGATCACCGCCAACTCACCGGAAACACTGATCCAGCTCGCCCGCGCCGGACAGGGCATC
GCGGCGGTGCCCGACTACTTCGCGGTGGCCCACGTGCGCCGCGGCGAGTTGCTGCGCGTGCTGCCCGAGTGGAGCCTGCC
GGCCAACACCGCGTGGGCGGTATTTCCCGGGCGCAAGCTGATGCCGGCGCGCACCCGCGCCTTCCTGGACATGGTGCTGG
CGGCGCTGCCCGACGACGCGCCGGGCGCGCCCTCGCCCCGCTGA

Upstream 100 bases:

>100_bases
CCTCTCGGTGTCGTGGGGGTTCGGGGTGCTGCGATGGATGCACTTTATTCTGATCAAAACCCGCTAAAAACCCGGACAAA
CGGATAACATTGTTCCCATC

Downstream 100 bases:

>100_bases
ACGCAGGCCGACGACGCGGGCTCGGGGGATGGCGGAACTTTCACCGCGCCACGGCGACGAAGCCCGGCCCGCGCGCCTCA
CCTACAATCGCGTCCGCACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEQFDANDLLIFARVAEGGSFSRAAERLGLPKSTVSRRITLLEERLGERLMLRTTRRLSLTDFGLHLLEHARQLAAEVDA
VASLAQHRQAQPSGRLRVSMPADFANHLLLDMLSAFVALHPAISLDLDLSPRRVDLIGENFDLAIRIGDLPDDASLAARR
IRSFPISLYAARDYLAERGTPRVPDDLMRHEALRLFGRSGEPTPWRLLNGEQHWEGLPPGRITANSPETLIQLARAGQGI
AAVPDYFAVAHVRRGELLRVLPEWSLPANTAWAVFPGRKLMPARTRAFLDMVLAALPDDAPGAPSPR

Sequences:

>Translated_307_residues
MEQFDANDLLIFARVAEGGSFSRAAERLGLPKSTVSRRITLLEERLGERLMLRTTRRLSLTDFGLHLLEHARQLAAEVDA
VASLAQHRQAQPSGRLRVSMPADFANHLLLDMLSAFVALHPAISLDLDLSPRRVDLIGENFDLAIRIGDLPDDASLAARR
IRSFPISLYAARDYLAERGTPRVPDDLMRHEALRLFGRSGEPTPWRLLNGEQHWEGLPPGRITANSPETLIQLARAGQGI
AAVPDYFAVAHVRRGELLRVLPEWSLPANTAWAVFPGRKLMPARTRAFLDMVLAALPDDAPGAPSPR
>Mature_307_residues
MEQFDANDLLIFARVAEGGSFSRAAERLGLPKSTVSRRITLLEERLGERLMLRTTRRLSLTDFGLHLLEHARQLAAEVDA
VASLAQHRQAQPSGRLRVSMPADFANHLLLDMLSAFVALHPAISLDLDLSPRRVDLIGENFDLAIRIGDLPDDASLAARR
IRSFPISLYAARDYLAERGTPRVPDDLMRHEALRLFGRSGEPTPWRLLNGEQHWEGLPPGRITANSPETLIQLARAGQGI
AAVPDYFAVAHVRRGELLRVLPEWSLPANTAWAVFPGRKLMPARTRAFLDMVLAALPDDAPGAPSPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=34.7079037800687, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1786401, Length=299, Percent_Identity=34.4481605351171, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789639, Length=281, Percent_Identity=30.6049822064057, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=30.0341296928328, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=31.986531986532, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789440, Length=270, Percent_Identity=29.6296296296296, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=28.125, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790011, Length=306, Percent_Identity=23.8562091503268, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789173, Length=297, Percent_Identity=27.9461279461279, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786713, Length=84, Percent_Identity=47.6190476190476, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=175, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33983; Mature: 33983

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFDANDLLIFARVAEGGSFSRAAERLGLPKSTVSRRITLLEERLGERLMLRTTRRLSL
CCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TDFGLHLLEHARQLAAEVDAVASLAQHRQAQPSGRLRVSMPADFANHLLLDMLSAFVALH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHC
PAISLDLDLSPRRVDLIGENFDLAIRIGDLPDDASLAARRIRSFPISLYAARDYLAERGT
CCEEEECCCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
PRVPDDLMRHEALRLFGRSGEPTPWRLLNGEQHWEGLPPGRITANSPETLIQLARAGQGI
CCCCHHHHHHHHHHHHCCCCCCCCEEECCCHHHCCCCCCCCEECCCHHHHHHHHHCCCCC
AAVPDYFAVAHVRRGELLRVLPEWSLPANTAWAVFPGRKLMPARTRAFLDMVLAALPDDA
CCCCHHHHHHHHHHCCHHEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
PGAPSPR
CCCCCCC
>Mature Secondary Structure
MEQFDANDLLIFARVAEGGSFSRAAERLGLPKSTVSRRITLLEERLGERLMLRTTRRLSL
CCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TDFGLHLLEHARQLAAEVDAVASLAQHRQAQPSGRLRVSMPADFANHLLLDMLSAFVALH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHC
PAISLDLDLSPRRVDLIGENFDLAIRIGDLPDDASLAARRIRSFPISLYAARDYLAERGT
CCEEEECCCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
PRVPDDLMRHEALRLFGRSGEPTPWRLLNGEQHWEGLPPGRITANSPETLIQLARAGQGI
CCCCHHHHHHHHHHHHCCCCCCCCEEECCCHHHCCCCCCCCEECCCHHHHHHHHHCCCCC
AAVPDYFAVAHVRRGELLRVLPEWSLPANTAWAVFPGRKLMPARTRAFLDMVLAALPDDA
CCCCHHHHHHHHHHCCHHEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
PGAPSPR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]