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The map label for this gene is mtnA [H]

Identifier: 119899649

GI number: 119899649

Start: 3696278

End: 3697354

Strand: Direct

Name: mtnA [H]

Synonym: azo3360

Alternate gene names: 119899649

Gene position: 3696278-3697354 (Clockwise)

Preceding gene: 119899637

Following gene: 119899650

Centisome position: 84.47

GC content: 73.91

Gene sequence:

>1077_bases
ATGACACCCTTCCGCTTCACCCAGCCCATCCCCACCCTGTGCCGCGACGGCGATAGCGTTCTGGTGCTGGACCAGACACG
CCTGCCCTGGCGTAGCGAGCAGCGCCGCCTGCGCACGCTGGACGAGGCGGCGGAAGCGATCCGCGCCATGTGGGTGCGCG
GCGCACCGCTGATCGGCGGCACGGCCGCCTACGGCGTGGCACTCGCGCTGACGGCGGACCCCGGCGACGACGCGCTCGAA
TACGCCCTCGCCACCCTCGCCGCCACCCGCCCCACCGCGGTGAACCTGCACTGGGCGCTGGCGCGCATGGCCGCGGCCTT
GCGCCCGCTGACACCCGGCGCGCGCCGCGCCGCCGCGTGGGACGAGGCGGCCGCGATCTGCGCTGACGACGTGCGCTGCT
GCGCTGCGATCGGCGCCCACGGTCTGCCGCTGCTGCAAGCCATCGCCGCGGTACGCGGACGGGTGCGGGTAATGACCCAC
TGCAACGCCGGCTGGCTGGCGACCATGGGGGCCGGAACGGCGCTGGCGCCGGTGTATGCGGCGCATCTTGCCGGGCTGGC
GGTCGAGGTCACCGTCAGCGAGACCCGGCCCCGCAACCAAGGGCTGCTGACGGCGTGGGAACTGCGTGAAGCGGGGGTGC
CGCACCGGTTGATCGCCGACAACGCCGCCGGCCTGCTGCTGGCACGCGGCGAAATCGACCTGGTCATCACCGGCGCGGAC
CGCATCGCCGCCAATGGCGACACGGCGAACAAGGTCGGCACCTACCTGAAGGCGCTCGCCGCGCGCGAAGCGGGCGTGCC
CTTCTACATCGCGGCCCCGCACTCCACGCTGGACTTCGGCTGCCCGGACGGCGACGCGATCCCGATCGAAGACCGCGGCG
CGGCCGAGGTGTGCACCGTGCGCGGCGCCGGCACGGATGGCGAACCGGCGGAGCTGCGGCTTGCGCCGGACGCCACTGCG
GCGGCCAACCCCGCCTTCGACGTCACGCCCGCCCGCTTCATCGCCGGCATCATCACCGAACGCGGCATCGCCGCTGCCGA
CGCGCTGGCGGCGCTGTATCCGGAGGACGCGCAATGA

Upstream 100 bases:

>100_bases
TCGCCCGTCATGCCCGCGGGCGCCCTGTCGCGCTTGCGGCCCCTGCCGCGCGCTGGCACATTCGACGGCTCCCCCAAACG
CCTCCGGCCACCGCCCCGCG

Downstream 100 bases:

>100_bases
ACACCGCGGATACGCTGCGCGAGCCGCTGCTTGCCACGGCCCGCGCGATGACCACAGCCGGCCTCAATGTCGGCGCTTCC
GGCAACGCCAGCGTGCGGCT

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTPFRFTQPIPTLCRDGDSVLVLDQTRLPWRSEQRRLRTLDEAAEAIRAMWVRGAPLIGGTAAYGVALALTADPGDDALE
YALATLAATRPTAVNLHWALARMAAALRPLTPGARRAAAWDEAAAICADDVRCCAAIGAHGLPLLQAIAAVRGRVRVMTH
CNAGWLATMGAGTALAPVYAAHLAGLAVEVTVSETRPRNQGLLTAWELREAGVPHRLIADNAAGLLLARGEIDLVITGAD
RIAANGDTANKVGTYLKALAAREAGVPFYIAAPHSTLDFGCPDGDAIPIEDRGAAEVCTVRGAGTDGEPAELRLAPDATA
AANPAFDVTPARFIAGIITERGIAAADALAALYPEDAQ

Sequences:

>Translated_358_residues
MTPFRFTQPIPTLCRDGDSVLVLDQTRLPWRSEQRRLRTLDEAAEAIRAMWVRGAPLIGGTAAYGVALALTADPGDDALE
YALATLAATRPTAVNLHWALARMAAALRPLTPGARRAAAWDEAAAICADDVRCCAAIGAHGLPLLQAIAAVRGRVRVMTH
CNAGWLATMGAGTALAPVYAAHLAGLAVEVTVSETRPRNQGLLTAWELREAGVPHRLIADNAAGLLLARGEIDLVITGAD
RIAANGDTANKVGTYLKALAAREAGVPFYIAAPHSTLDFGCPDGDAIPIEDRGAAEVCTVRGAGTDGEPAELRLAPDATA
AANPAFDVTPARFIAGIITERGIAAADALAALYPEDAQ
>Mature_357_residues
TPFRFTQPIPTLCRDGDSVLVLDQTRLPWRSEQRRLRTLDEAAEAIRAMWVRGAPLIGGTAAYGVALALTADPGDDALEY
ALATLAATRPTAVNLHWALARMAAALRPLTPGARRAAAWDEAAAICADDVRCCAAIGAHGLPLLQAIAAVRGRVRVMTHC
NAGWLATMGAGTALAPVYAAHLAGLAVEVTVSETRPRNQGLLTAWELREAGVPHRLIADNAAGLLLARGEIDLVITGADR
IAANGDTANKVGTYLKALAAREAGVPFYIAAPHSTLDFGCPDGDAIPIEDRGAAEVCTVRGAGTDGEPAELRLAPDATAA
ANPAFDVTPARFIAGIITERGIAAADALAALYPEDAQ

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=354, Percent_Identity=40.1129943502825, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI23943880, Length=347, Percent_Identity=36.0230547550432, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17557462, Length=357, Percent_Identity=31.6526610644258, Blast_Score=168, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6325375, Length=385, Percent_Identity=31.6883116883117, Blast_Score=159, Evalue=9e-40,
Organism=Drosophila melanogaster, GI21357667, Length=348, Percent_Identity=39.0804597701149, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24651647, Length=348, Percent_Identity=39.0804597701149, Blast_Score=192, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 37268; Mature: 37137

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPFRFTQPIPTLCRDGDSVLVLDQTRLPWRSEQRRLRTLDEAAEAIRAMWVRGAPLIGG
CCCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TAAYGVALALTADPGDDALEYALATLAATRPTAVNLHWALARMAAALRPLTPGARRAAAW
HHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHH
DEAAAICADDVRCCAAIGAHGLPLLQAIAAVRGRVRVMTHCNAGWLATMGAGTALAPVYA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCEEECCCCHHHHHHHH
AHLAGLAVEVTVSETRPRNQGLLTAWELREAGVPHRLIADNAAGLLLARGEIDLVITGAD
HHHCCEEEEEEEECCCCCCCCCEEEEHHHHCCCCCEEECCCCCEEEEECCCEEEEEECCC
RIAANGDTANKVGTYLKALAAREAGVPFYIAAPHSTLDFGCPDGDAIPIEDRGAAEVCTV
CEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCEEEEE
RGAGTDGEPAELRLAPDATAAANPAFDVTPARFIAGIITERGIAAADALAALYPEDAQ
ECCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPFRFTQPIPTLCRDGDSVLVLDQTRLPWRSEQRRLRTLDEAAEAIRAMWVRGAPLIGG
CCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TAAYGVALALTADPGDDALEYALATLAATRPTAVNLHWALARMAAALRPLTPGARRAAAW
HHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHH
DEAAAICADDVRCCAAIGAHGLPLLQAIAAVRGRVRVMTHCNAGWLATMGAGTALAPVYA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCEEECCCCHHHHHHHH
AHLAGLAVEVTVSETRPRNQGLLTAWELREAGVPHRLIADNAAGLLLARGEIDLVITGAD
HHHCCEEEEEEEECCCCCCCCCEEEEHHHHCCCCCEEECCCCCEEEEECCCEEEEEECCC
RIAANGDTANKVGTYLKALAAREAGVPFYIAAPHSTLDFGCPDGDAIPIEDRGAAEVCTV
CEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCEEEEE
RGAGTDGEPAELRLAPDATAAANPAFDVTPARFIAGIITERGIAAADALAALYPEDAQ
ECCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA