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The map label for this gene is ybdL [H]

Identifier: 119899648

GI number: 119899648

Start: 3694971

End: 3696188

Strand: Reverse

Name: ybdL [H]

Synonym: azo3359

Alternate gene names: 119899648

Gene position: 3696188-3694971 (Counterclockwise)

Preceding gene: 119899651

Following gene: 119899647

Centisome position: 84.46

GC content: 68.72

Gene sequence:

>1218_bases
ATGACGGGCGATCGCCACGGGTGCGAGAATGCGGCCCTTGTCCGCCGCCGCGAGGCCGCCATGCCGCACTTTCCCGCTCC
GGTCGTTTCCCGCCTGCCGCAGGTGGGCACCACGATCTTCACCGTGATGTCGCGCCTCGCGCAGGAGTGTGGCGCGATCA
ACCTGTCGCAGGGCTTCCCCGACTTCAATGCCGACGACGCGCTGTTCGAGCGCGTGGCGCACTGGATGCGCACCGGGCAC
AACCAGTACGCGCCGATGGCCGGCGTGCCCGCACTGCGCGAGGCGGTGGCGGGCAAGGTGGCGGCGCTGTACGGCAGCAC
GTACGACGTCGAACACGAGGTGACGATTACCGCGGGCGCCACCCAGGCGCTGTTCACCGCGGTGGCGGCCTTGGTGCATC
CGGGCGACGAGGTGATCGTGTTCGAGCCGGTGTACGACTCCTATGGCCCCGCGGTCGAGCTGGCCGGGGGCCGCGTGGTG
CGCATGCAGTTGGCGGCGCCGGATTACCGCCCCGACTGGGCGGCGGTGGCCGCGGCAATCACCCCGCGTACCCGCATGAT
CATGATCAACTCGCCGCACAACCCCACCGCCACGGTGTGGACCGCGGCGGACTACGACCGCCTCGCGGCGCTGCTGCGCG
ATACCGGCATCATCGTGGTGTCGGACGAGGTGTATGAACACATCGTGTTCGACGGCCTGCAGCACCGCAGCTGCGCCGCC
CATCCGGAACTCGCCGCGCGCAGCATCGTGGTGTCCAGCTTCGGCAAGACCTACCACATCACCGGCTGGAAGGTGGGCTA
TGTGGTGGCGCCGCGCGAGTTGATGGCGGAGTTCCGCAAGGTGCACCAGTTCAACGTGTTCACGGTGAATACGCCGGTGC
AGTACGCGCTGGCCGACTACATGGCGGAGGCCTCGCGCCATCTCGGCCTGGCGGCCTTCTACCAGGCCAAGCGCAACCTG
TTCCGCGACGCGCTCGCCGGCTCCCGCTTCGAGCTGCTGCCGTCGCGCGGCACCTATTTCCAGCTGGCGCGCTACAGCGC
CATTTCCGACGAGGGCGACGTCGCGTTCTGCAACCGGCTCGCGCGGCAAGTGGGGGTCGCCGCGATTCCGGTTTCGGCCT
TCTTTGCCGACGGCCGCGACGAGCGCGTGATCCGCTTCTGCTTTGCCAAGAACGACACCACGCTGAACGCTGCCTGCGAG
CGTCTGCGGGCCCTGTAA

Upstream 100 bases:

>100_bases
AAGGGTGTCATCGCGGGGCGGTGGCCGGAGGCGTTTGGGGGAGCCGTCGAATGTGCCAGCGCGCGGCAGGGGCCGCAAGC
GCGACAGGGCGCCCGCGGGC

Downstream 100 bases:

>100_bases
ACGCCCGCAGGAAGCGGTGCAGGACAGCAGGCGGATGGGCAGTGGCGCCGGGCGTGCGTGATAAACTGCCGCGGTTTTCC
GGTTCGCAATTTTCCGCTTC

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTGDRHGCENAALVRRREAAMPHFPAPVVSRLPQVGTTIFTVMSRLAQECGAINLSQGFPDFNADDALFERVAHWMRTGH
NQYAPMAGVPALREAVAGKVAALYGSTYDVEHEVTITAGATQALFTAVAALVHPGDEVIVFEPVYDSYGPAVELAGGRVV
RMQLAAPDYRPDWAAVAAAITPRTRMIMINSPHNPTATVWTAADYDRLAALLRDTGIIVVSDEVYEHIVFDGLQHRSCAA
HPELAARSIVVSSFGKTYHITGWKVGYVVAPRELMAEFRKVHQFNVFTVNTPVQYALADYMAEASRHLGLAAFYQAKRNL
FRDALAGSRFELLPSRGTYFQLARYSAISDEGDVAFCNRLARQVGVAAIPVSAFFADGRDERVIRFCFAKNDTTLNAACE
RLRAL

Sequences:

>Translated_405_residues
MTGDRHGCENAALVRRREAAMPHFPAPVVSRLPQVGTTIFTVMSRLAQECGAINLSQGFPDFNADDALFERVAHWMRTGH
NQYAPMAGVPALREAVAGKVAALYGSTYDVEHEVTITAGATQALFTAVAALVHPGDEVIVFEPVYDSYGPAVELAGGRVV
RMQLAAPDYRPDWAAVAAAITPRTRMIMINSPHNPTATVWTAADYDRLAALLRDTGIIVVSDEVYEHIVFDGLQHRSCAA
HPELAARSIVVSSFGKTYHITGWKVGYVVAPRELMAEFRKVHQFNVFTVNTPVQYALADYMAEASRHLGLAAFYQAKRNL
FRDALAGSRFELLPSRGTYFQLARYSAISDEGDVAFCNRLARQVGVAAIPVSAFFADGRDERVIRFCFAKNDTTLNAACE
RLRAL
>Mature_404_residues
TGDRHGCENAALVRRREAAMPHFPAPVVSRLPQVGTTIFTVMSRLAQECGAINLSQGFPDFNADDALFERVAHWMRTGHN
QYAPMAGVPALREAVAGKVAALYGSTYDVEHEVTITAGATQALFTAVAALVHPGDEVIVFEPVYDSYGPAVELAGGRVVR
MQLAAPDYRPDWAAVAAAITPRTRMIMINSPHNPTATVWTAADYDRLAALLRDTGIIVVSDEVYEHIVFDGLQHRSCAAH
PELAARSIVVSSFGKTYHITGWKVGYVVAPRELMAEFRKVHQFNVFTVNTPVQYALADYMAEASRHLGLAAFYQAKRNLF
RDALAGSRFELLPSRGTYFQLARYSAISDEGDVAFCNRLARQVGVAAIPVSAFFADGRDERVIRFCFAKNDTTLNAACER
LRAL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=408, Percent_Identity=32.1078431372549, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI169881279, Length=408, Percent_Identity=32.1078431372549, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI56713254, Length=405, Percent_Identity=30.1234567901235, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI56713256, Length=406, Percent_Identity=30.0492610837438, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI169881281, Length=407, Percent_Identity=27.5184275184275, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=22.8723404255319, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=56.2334217506631, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=24.8704663212435, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788627, Length=272, Percent_Identity=28.6764705882353, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787710, Length=296, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=430, Percent_Identity=33.4883720930233, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71994476, Length=417, Percent_Identity=33.5731414868106, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=31.4070351758794, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17567663, Length=351, Percent_Identity=23.0769230769231, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=29.9741602067183, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI28573069, Length=422, Percent_Identity=30.8056872037915, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24646114, Length=422, Percent_Identity=30.8056872037915, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI28573067, Length=422, Percent_Identity=30.8056872037915, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI28573065, Length=422, Percent_Identity=30.8056872037915, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI18859735, Length=366, Percent_Identity=23.7704918032787, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 44413; Mature: 44282

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDRHGCENAALVRRREAAMPHFPAPVVSRLPQVGTTIFTVMSRLAQECGAINLSQGFP
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCEECCCCCC
DFNADDALFERVAHWMRTGHNQYAPMAGVPALREAVAGKVAALYGSTYDVEHEVTITAGA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
TQALFTAVAALVHPGDEVIVFEPVYDSYGPAVELAGGRVVRMQLAAPDYRPDWAAVAAAI
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHC
TPRTRMIMINSPHNPTATVWTAADYDRLAALLRDTGIIVVSDEVYEHIVFDGLQHRSCAA
CCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCCCC
HPELAARSIVVSSFGKTYHITGWKVGYVVAPRELMAEFRKVHQFNVFTVNTPVQYALADY
CHHHHHHHHHHHHCCCEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHHHHHH
MAEASRHLGLAAFYQAKRNLFRDALAGSRFELLPSRGTYFQLARYSAISDEGDVAFCNRL
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEHHHCCCCCCCHHHHHHH
ARQVGVAAIPVSAFFADGRDERVIRFCFAKNDTTLNAACERLRAL
HHHHCCEEEEHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TGDRHGCENAALVRRREAAMPHFPAPVVSRLPQVGTTIFTVMSRLAQECGAINLSQGFP
CCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCEECCCCCC
DFNADDALFERVAHWMRTGHNQYAPMAGVPALREAVAGKVAALYGSTYDVEHEVTITAGA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
TQALFTAVAALVHPGDEVIVFEPVYDSYGPAVELAGGRVVRMQLAAPDYRPDWAAVAAAI
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHC
TPRTRMIMINSPHNPTATVWTAADYDRLAALLRDTGIIVVSDEVYEHIVFDGLQHRSCAA
CCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCCCC
HPELAARSIVVSSFGKTYHITGWKVGYVVAPRELMAEFRKVHQFNVFTVNTPVQYALADY
CHHHHHHHHHHHHCCCEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHHHHHH
MAEASRHLGLAAFYQAKRNLFRDALAGSRFELLPSRGTYFQLARYSAISDEGDVAFCNRL
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEHHHCCCCCCCHHHHHHH
ARQVGVAAIPVSAFFADGRDERVIRFCFAKNDTTLNAACERLRAL
HHHHCCEEEEHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]