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The map label for this gene is cbbZ [C]

Identifier: 119899615

GI number: 119899615

Start: 3666394

End: 3667065

Strand: Reverse

Name: cbbZ [C]

Synonym: azo3326

Alternate gene names: 119899615

Gene position: 3667065-3666394 (Counterclockwise)

Preceding gene: 119899616

Following gene: 119899614

Centisome position: 83.8

GC content: 64.58

Gene sequence:

>672_bases
ATGACGCATTTTCCCGCCCGCGCAGTGCTGTTCGACCTCGACGGCACGCTGCTCGACACCATCGGCGACCTCGCCGAAGC
AGCCAACCGCATGCTCTCCGAACTCGGTCGGCCGCAACGACCGTTGGAGGAAATCCACAGCTTCGTCGGCAAGGGGTTGC
CAAACCTGGTGTACCGCTGCCTCGCCGAGAACGCCTCGGCGACCGAAGCCGACGTGGATGCCGCGATCCCGGTGTTCCGC
CGCCATTACATCGCGGTCAATGGCGACACCACGCGCATCTACCCCGGCATTGTCGAAACTCTGGAGACCCTGCGCGCGCG
CCGACTCAAACTCGCGGTGGTGACCAACAAGGCGGGCGATTTCACCCTTCCACTGCTCGAACGCATGGACATCGCCCGCT
ATTTCCAGGCCGTCGTCAGCGGCGACACCCTGCCGGTGAAGAAGCCCGATCCGGCGATGCTGATTCATGCGTGCGAGCTG
CTCGGCGTGAGTCCGCGCGAGGCCGTGATGATCGGCGACTCGGCCAACGACGCGCTCGCGGCCCGCGCTGCGGGCATGCC
GGTACTGCTCGTCAGCTATGGCTACAGCGAGGGCATGCCGGTGGACACTATCGAATGCGATGGGCTACTATCCGACGCAC
TTCAGGCGCTGGACCATATCATTCCGGCATGA

Upstream 100 bases:

>100_bases
CGGCGCGGGCAAGGACAGCGACCCCAACCGCTACGACGGCGTGATCGGCGCGCTGCGTGCCGAGCTTGCCGCGGTCGGCA
CCCCGGGCTGAGCGAACGCG

Downstream 100 bases:

>100_bases
ACGCCGGACAGCGCCGCTCCAGCTGCGGTAGCTCACCTCACACAGAAAGCATCGTGACTCTCGAACAGCGGTTCCCGGAA
AAGGATTTTGCGACCGTCTC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTHFPARAVLFDLDGTLLDTIGDLAEAANRMLSELGRPQRPLEEIHSFVGKGLPNLVYRCLAENASATEADVDAAIPVFR
RHYIAVNGDTTRIYPGIVETLETLRARRLKLAVVTNKAGDFTLPLLERMDIARYFQAVVSGDTLPVKKPDPAMLIHACEL
LGVSPREAVMIGDSANDALAARAAGMPVLLVSYGYSEGMPVDTIECDGLLSDALQALDHIIPA

Sequences:

>Translated_223_residues
MTHFPARAVLFDLDGTLLDTIGDLAEAANRMLSELGRPQRPLEEIHSFVGKGLPNLVYRCLAENASATEADVDAAIPVFR
RHYIAVNGDTTRIYPGIVETLETLRARRLKLAVVTNKAGDFTLPLLERMDIARYFQAVVSGDTLPVKKPDPAMLIHACEL
LGVSPREAVMIGDSANDALAARAAGMPVLLVSYGYSEGMPVDTIECDGLLSDALQALDHIIPA
>Mature_222_residues
THFPARAVLFDLDGTLLDTIGDLAEAANRMLSELGRPQRPLEEIHSFVGKGLPNLVYRCLAENASATEADVDAAIPVFRR
HYIAVNGDTTRIYPGIVETLETLRARRLKLAVVTNKAGDFTLPLLERMDIARYFQAVVSGDTLPVKKPDPAMLIHACELL
GVSPREAVMIGDSANDALAARAAGMPVLLVSYGYSEGMPVDTIECDGLLSDALQALDHIIPA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=235, Percent_Identity=36.5957446808511, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24080; Mature: 23949

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFPARAVLFDLDGTLLDTIGDLAEAANRMLSELGRPQRPLEEIHSFVGKGLPNLVYRC
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
LAENASATEADVDAAIPVFRRHYIAVNGDTTRIYPGIVETLETLRARRLKLAVVTNKAGD
HHCCCCCCHHHHHHHHHHHHHEEEEECCCCCEECHHHHHHHHHHHHHHEEEEEEECCCCC
FTLPLLERMDIARYFQAVVSGDTLPVKKPDPAMLIHACELLGVSPREAVMIGDSANDALA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
ARAAGMPVLLVSYGYSEGMPVDTIECDGLLSDALQALDHIIPA
HHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
THFPARAVLFDLDGTLLDTIGDLAEAANRMLSELGRPQRPLEEIHSFVGKGLPNLVYRC
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
LAENASATEADVDAAIPVFRRHYIAVNGDTTRIYPGIVETLETLRARRLKLAVVTNKAGD
HHCCCCCCHHHHHHHHHHHHHEEEEECCCCCEECHHHHHHHHHHHHHHEEEEEEECCCCC
FTLPLLERMDIARYFQAVVSGDTLPVKKPDPAMLIHACELLGVSPREAVMIGDSANDALA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
ARAAGMPVLLVSYGYSEGMPVDTIECDGLLSDALQALDHIIPA
HHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA