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The map label for this gene is argB [H]

Identifier: 119899533

GI number: 119899533

Start: 3574680

End: 3575582

Strand: Direct

Name: argB [H]

Synonym: azo3244

Alternate gene names: 119899533

Gene position: 3574680-3575582 (Clockwise)

Preceding gene: 119899532

Following gene: 119899534

Centisome position: 81.69

GC content: 63.79

Gene sequence:

>903_bases
ATGTCCGCCGCAAGTTCCACCGAATCCGTTACCCCTGCCCTGAAGGCCGAGATCCTCGCCGAGGCCCTACCCTACATCAA
ACGCTTCTTCGACAAGACCATCGTCATCAAGTACGGCGGCAACGCGATGACCGACCCGCACCTCAAGGACTGCTTCGCGC
GCGACGTGGTGCTGCTCAAGCTGGTCGGCCTCAACCCGGTGGTGGTGCACGGCGGCGGTCCGCAGATCGAAACCCTGCTC
GCCAAGGTCGGCAAGAAGGGCGAATTCGTGCAAGGCATGCGCGTCACCGACGCCGAGACCATGGAGGTGGTCGAGATGGT
GCTCGGTGGCCAGGTGAACAAGGAGATCGTCAATCTCATCAACCAGGCGGGCGGCAAGGCGGTCGGTCTCACCGGCAAAG
ACGCCAGCTTCATCCGTGCCAAGAAGCTGCTGATGCAGAAGCTGGATGCGCCCGCAGGCGACGTGATCGATGTCGGCCAG
GTGGGCGAGATCACCACCATCGACCCCAGCCTGATCTCCTTCCTCGACCAGGGCGACTTCATCCCGGTGATCGCACCGAT
CGGCGTCGGCGACAACGGCGAGACCTACAACATCAACGCCGACGTGGTCGCGGGCAAGCTCGCCGAGATCCTCAAGGCCG
AAAAGCTGGTGCTGCTCACCAATACGCCGGGCGTGCTCGACAAGGCCGGCAACCTGCTTACCGGCCTGACCCCGCGGCAG
ATCGACGACCTCGTGGCCGACGGCACGCTCTCGGGCGGCATGCTGCCCAAGATCGGCTCGGCGCTCGATGCCGCACGCAA
CGGGGTCAAGTCGGTGCACATCATCGACGGACGGGTGGAGCACTGCCTGCTGCTCGAAATCCTGACCGACCACGGCGTCG
GTACGATGATCAAGAGCAAGTAA

Upstream 100 bases:

>100_bases
CCGCGGCGGCGCGCAAAACAGGCGGAAGGCTCCCGGGCCTTCCGCTTTTTGTTTGCTGCTCAGGCCACTACAATCGCCGC
ACCGTTTCCGGAGAAACCCG

Downstream 100 bases:

>100_bases
GCCGATGCGCCGCCTCTGCACCTTCCTGCATGCGGCGCTTCTGGCAACGTGGGCGGGGTCCGCCCACGCTGCCGTGCTCA
CCGTCGGCCCCGGCGAGACC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSAASSTESVTPALKAEILAEALPYIKRFFDKTIVIKYGGNAMTDPHLKDCFARDVVLLKLVGLNPVVVHGGGPQIETLL
AKVGKKGEFVQGMRVTDAETMEVVEMVLGGQVNKEIVNLINQAGGKAVGLTGKDASFIRAKKLLMQKLDAPAGDVIDVGQ
VGEITTIDPSLISFLDQGDFIPVIAPIGVGDNGETYNINADVVAGKLAEILKAEKLVLLTNTPGVLDKAGNLLTGLTPRQ
IDDLVADGTLSGGMLPKIGSALDAARNGVKSVHIIDGRVEHCLLLEILTDHGVGTMIKSK

Sequences:

>Translated_300_residues
MSAASSTESVTPALKAEILAEALPYIKRFFDKTIVIKYGGNAMTDPHLKDCFARDVVLLKLVGLNPVVVHGGGPQIETLL
AKVGKKGEFVQGMRVTDAETMEVVEMVLGGQVNKEIVNLINQAGGKAVGLTGKDASFIRAKKLLMQKLDAPAGDVIDVGQ
VGEITTIDPSLISFLDQGDFIPVIAPIGVGDNGETYNINADVVAGKLAEILKAEKLVLLTNTPGVLDKAGNLLTGLTPRQ
IDDLVADGTLSGGMLPKIGSALDAARNGVKSVHIIDGRVEHCLLLEILTDHGVGTMIKSK
>Mature_299_residues
SAASSTESVTPALKAEILAEALPYIKRFFDKTIVIKYGGNAMTDPHLKDCFARDVVLLKLVGLNPVVVHGGGPQIETLLA
KVGKKGEFVQGMRVTDAETMEVVEMVLGGQVNKEIVNLINQAGGKAVGLTGKDASFIRAKKLLMQKLDAPAGDVIDVGQV
GEITTIDPSLISFLDQGDFIPVIAPIGVGDNGETYNINADVVAGKLAEILKAEKLVLLTNTPGVLDKAGNLLTGLTPRQI
DDLVADGTLSGGMLPKIGSALDAARNGVKSVHIIDGRVEHCLLLEILTDHGVGTMIKSK

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=286, Percent_Identity=29.020979020979, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693208, Length=212, Percent_Identity=32.0754716981132, Blast_Score=88, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=289, Percent_Identity=28.719723183391, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 31522; Mature: 31391

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASSTESVTPALKAEILAEALPYIKRFFDKTIVIKYGGNAMTDPHLKDCFARDVVLLK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
LVGLNPVVVHGGGPQIETLLAKVGKKGEFVQGMRVTDAETMEVVEMVLGGQVNKEIVNLI
EECCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
NQAGGKAVGLTGKDASFIRAKKLLMQKLDAPAGDVIDVGQVGEITTIDPSLISFLDQGDF
HHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEECCHHHHHHHCCCCC
IPVIAPIGVGDNGETYNINADVVAGKLAEILKAEKLVLLTNTPGVLDKAGNLLTGLTPRQ
EEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCHHHCCCHHH
IDDLVADGTLSGGMLPKIGSALDAARNGVKSVHIIDGRVEHCLLLEILTDHGVGTMIKSK
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCEECCC
>Mature Secondary Structure 
SAASSTESVTPALKAEILAEALPYIKRFFDKTIVIKYGGNAMTDPHLKDCFARDVVLLK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
LVGLNPVVVHGGGPQIETLLAKVGKKGEFVQGMRVTDAETMEVVEMVLGGQVNKEIVNLI
EECCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
NQAGGKAVGLTGKDASFIRAKKLLMQKLDAPAGDVIDVGQVGEITTIDPSLISFLDQGDF
HHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEECCHHHHHHHCCCCC
IPVIAPIGVGDNGETYNINADVVAGKLAEILKAEKLVLLTNTPGVLDKAGNLLTGLTPRQ
EEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCHHHCCCHHH
IDDLVADGTLSGGMLPKIGSALDAARNGVKSVHIIDGRVEHCLLLEILTDHGVGTMIKSK
HHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA