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The map label for this gene is aspS

Identifier: 119899528

GI number: 119899528

Start: 3569566

End: 3571365

Strand: Direct

Name: aspS

Synonym: azo3239

Alternate gene names: 119899528

Gene position: 3569566-3571365 (Clockwise)

Preceding gene: 119899527

Following gene: 119899529

Centisome position: 81.57

GC content: 65.39

Gene sequence:

>1800_bases
ATGCGAACTCAATACTGCGGCCAAGTCACCGCCGCCCACCTCGACCAGATCGTCACCCTGTGCGGCTGGGTGCATCGCCG
CCGCGACCACGGCGGGGTGATCTTCATCGACCTGCGCGACCGTGAAGGTCTCGTTCAGGTGGTGTGCGATCCGGATCGCG
CGGAAATGTTCAAGACCGCCGAATCGGTGCGCAACGAGTTCGTGCTCAAGATGACCGGCAAGGTGCGCCGCCGCCCGGCC
GGCACCGAAAACGCCAACCTCACCTCCGGCGAAATCGAAGTGCTGTGCCACGAGATCGAGGTGCTCAACACCTCGGCCAC
GCCCCCGTTCCAGCTCGACGACGAGAACCTGTCGGAAACGGTCCGCCTGACCAACCGCGTCATCGACCTGCGCCGCCCGC
AGATGCAGAAGAACCTGATGCTGCGCTACAAGGTGGCGATGGCCTTCCGCCGCTTCCTCGACGGCGCCGGCTTCATCGAC
GTCGAAACGCCGATGCTCACCAAGAGCACGCCGGAAGGCGCGCGCGACTACCTGGTGCCGTCGCGCGTGCATCCGGGCCA
GTTCTTCGCACTGCCGCAGTCGCCGCAGCTCTTCAAGCAGCTGCTGATGGTGGCCGGCTTCGACCGCTACTACCAGATCA
CCAAGTGCTTCCGCGACGAGGATCTGCGCGCCGACCGCCAGCCGGAATTCACCCAGGTAGATATCGAGACCTCCTTCCTC
AACGAAACCGAGATCACCGCCCTGATGGAGGAGATGATCCGCTTCGTGTTCAAGGAATCGCTCGGCGTCGACCTGCCCTC
GCCCTTCCCGCGCATGACCTACGCCGAGGCGATGCGCCGCTACGGCTCTGACAAGCCCGATCTGCGCGTCACCCTGGAAC
TGACCGAAGTCACCGACCTGATGAAGGACGTGGCCTTCAAGGTCTTCTCCGGCCCGGCCAATTCGGGCGGCCGTGTCGCC
GCGATGCGCGTGCCGGGCGGTGCCACCCTGACCCGCGGCGAGATTGACGAATACACCAAGTTCGTCGGCATCTACGGTGC
CAAGGGCCTGGCCTACATCAAGGTCAACGACGCCAGCCAGCCCAACGAGACCGGCCTGCAGTCGCCCATCGTCAAGAACC
TGTCCGAAGCGGCGCTGCGTGGCGTGATCGAGCGTACCGGCGCCCAGTCCGGCGACCTGATCTTCTTCGGCGCCGACAAG
GCCAAGGTGGTGAATGACGCCATCGGCGCGCTGCGCATCAAGCTGGGCCACGAAAAGGGTTATGTCACCGGCGACGCCTG
GCGTCCGCTGTGGGTGGTCGACTTCCCGATGTTCGAGTACGACGAGGACGACAAGCGCTGGACCGCCTGTCACCACCCCT
TCACCAGCCCCAAGGACGAGCACGTCGAACTGCTCAAGACCAACCCGGGCGAGTGCCTCGCCAAGGCCTACGACCTCGCG
CTCAACGGCTGGGAAATCGGCGGCGGCTCGGTGCGTATCCACCGCGCCGACGTCCAGGCCACGGTGTTCGAGGCGCTCAA
CATCGGCGCCGAAGAGCAGCAGGTCAAGTTCGGCTTCCTGCTCGACGCACTCAAGTTCGGCGCACCGCCGCACGGCGGCC
TCGCCTTCGGTCTCGACCGCGTGGTCACGATGATGGCCGGCGCCGAGTCCATCCGCGACGTCATCGCCTTCCCCAAGACC
CAGCGCGCCCAGTGCCTGCTGACCAATGCGCCGGGCGAAGTCGACGAGAAGCAACTGCGCGAATTGCACATCCGCCTGCG
CCAGAAGGTGGAAACCCAGGTGGAAGTCGGCAAGGCCTGA

Upstream 100 bases:

>100_bases
CCTGTGCGCAAACCCGTCGAGCGCCCCGCTCTCCTCAACGACTAGACCCGTCCCGCTGCGGCCCGTCCGGGGCCGTAGCC
GAACAGCTGGAATCTTCATC

Downstream 100 bases:

>100_bases
CGCTGCATGTCGGATCATTCCGGAACTGGAAGGCGGTGACGAGAGTCCCGCCTTTTGTTTTTTGATCGCCTCCGAACGCT
TCAGGATTCCGCCCCGCTTG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MRTQYCGQVTAAHLDQIVTLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKTAESVRNEFVLKMTGKVRRRPA
GTENANLTSGEIEVLCHEIEVLNTSATPPFQLDDENLSETVRLTNRVIDLRRPQMQKNLMLRYKVAMAFRRFLDGAGFID
VETPMLTKSTPEGARDYLVPSRVHPGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQVDIETSFL
NETEITALMEEMIRFVFKESLGVDLPSPFPRMTYAEAMRRYGSDKPDLRVTLELTEVTDLMKDVAFKVFSGPANSGGRVA
AMRVPGGATLTRGEIDEYTKFVGIYGAKGLAYIKVNDASQPNETGLQSPIVKNLSEAALRGVIERTGAQSGDLIFFGADK
AKVVNDAIGALRIKLGHEKGYVTGDAWRPLWVVDFPMFEYDEDDKRWTACHHPFTSPKDEHVELLKTNPGECLAKAYDLA
LNGWEIGGGSVRIHRADVQATVFEALNIGAEEQQVKFGFLLDALKFGAPPHGGLAFGLDRVVTMMAGAESIRDVIAFPKT
QRAQCLLTNAPGEVDEKQLRELHIRLRQKVETQVEVGKA

Sequences:

>Translated_599_residues
MRTQYCGQVTAAHLDQIVTLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKTAESVRNEFVLKMTGKVRRRPA
GTENANLTSGEIEVLCHEIEVLNTSATPPFQLDDENLSETVRLTNRVIDLRRPQMQKNLMLRYKVAMAFRRFLDGAGFID
VETPMLTKSTPEGARDYLVPSRVHPGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQVDIETSFL
NETEITALMEEMIRFVFKESLGVDLPSPFPRMTYAEAMRRYGSDKPDLRVTLELTEVTDLMKDVAFKVFSGPANSGGRVA
AMRVPGGATLTRGEIDEYTKFVGIYGAKGLAYIKVNDASQPNETGLQSPIVKNLSEAALRGVIERTGAQSGDLIFFGADK
AKVVNDAIGALRIKLGHEKGYVTGDAWRPLWVVDFPMFEYDEDDKRWTACHHPFTSPKDEHVELLKTNPGECLAKAYDLA
LNGWEIGGGSVRIHRADVQATVFEALNIGAEEQQVKFGFLLDALKFGAPPHGGLAFGLDRVVTMMAGAESIRDVIAFPKT
QRAQCLLTNAPGEVDEKQLRELHIRLRQKVETQVEVGKA
>Mature_599_residues
MRTQYCGQVTAAHLDQIVTLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKTAESVRNEFVLKMTGKVRRRPA
GTENANLTSGEIEVLCHEIEVLNTSATPPFQLDDENLSETVRLTNRVIDLRRPQMQKNLMLRYKVAMAFRRFLDGAGFID
VETPMLTKSTPEGARDYLVPSRVHPGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQVDIETSFL
NETEITALMEEMIRFVFKESLGVDLPSPFPRMTYAEAMRRYGSDKPDLRVTLELTEVTDLMKDVAFKVFSGPANSGGRVA
AMRVPGGATLTRGEIDEYTKFVGIYGAKGLAYIKVNDASQPNETGLQSPIVKNLSEAALRGVIERTGAQSGDLIFFGADK
AKVVNDAIGALRIKLGHEKGYVTGDAWRPLWVVDFPMFEYDEDDKRWTACHHPFTSPKDEHVELLKTNPGECLAKAYDLA
LNGWEIGGGSVRIHRADVQATVFEALNIGAEEQQVKFGFLLDALKFGAPPHGGLAFGLDRVVTMMAGAESIRDVIAFPKT
QRAQCLLTNAPGEVDEKQLRELHIRLRQKVETQVEVGKA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=610, Percent_Identity=39.672131147541, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI45439306, Length=250, Percent_Identity=30, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI5031815, Length=317, Percent_Identity=23.9747634069401, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194272210, Length=317, Percent_Identity=23.9747634069401, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4758762, Length=290, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1788173, Length=594, Percent_Identity=58.4175084175084, Blast_Score=714, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=287, Percent_Identity=27.8745644599303, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1789256, Length=286, Percent_Identity=25.8741258741259, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI32566633, Length=610, Percent_Identity=34.9180327868852, Blast_Score=334, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17551876, Length=276, Percent_Identity=26.8115942028986, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71994340, Length=257, Percent_Identity=24.124513618677, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535927, Length=257, Percent_Identity=24.124513618677, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535925, Length=257, Percent_Identity=24.124513618677, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325153, Length=312, Percent_Identity=37.1794871794872, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6323011, Length=286, Percent_Identity=29.3706293706294, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324256, Length=259, Percent_Identity=24.7104247104247, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320242, Length=260, Percent_Identity=24.2307692307692, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321807, Length=286, Percent_Identity=23.4265734265734, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584738, Length=599, Percent_Identity=36.7278797996661, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI17136276, Length=256, Percent_Identity=29.296875, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24640849, Length=252, Percent_Identity=25.7936507936508, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640851, Length=252, Percent_Identity=25.7936507936508, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921528, Length=294, Percent_Identity=29.2517006802721, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_AZOSB (A1KAJ9)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934741.1
- ProteinModelPortal:   A1KAJ9
- SMR:   A1KAJ9
- STRING:   A1KAJ9
- GeneID:   4607862
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo3239
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- PhylomeDB:   A1KAJ9
- ProtClustDB:   PRK00476
- BioCyc:   ASP62928:AZO3239-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 67095; Mature: 67095

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTQYCGQVTAAHLDQIVTLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHH
ESVRNEFVLKMTGKVRRRPAGTENANLTSGEIEVLCHEIEVLNTSATPPFQLDDENLSET
HHHHHHEEEEECCHHHCCCCCCCCCCCCCCHHHEEEEEHHEEECCCCCCCEECCCCHHHH
VRLTNRVIDLRRPQMQKNLMLRYKVAMAFRRFLDGAGFIDVETPMLTKSTPEGARDYLVP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHCCCC
SRVHPGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQVDIETSFL
CCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHC
NETEITALMEEMIRFVFKESLGVDLPSPFPRMTYAEAMRRYGSDKPDLRVTLELTEVTDL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHH
MKDVAFKVFSGPANSGGRVAAMRVPGGATLTRGEIDEYTKFVGIYGAKGLAYIKVNDASQ
HHHHHHHHCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHEECCCCEEEEEECCCCC
PNETGLQSPIVKNLSEAALRGVIERTGAQSGDLIFFGADKAKVVNDAIGALRIKLGHEKG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCEEEEEECCCCC
YVTGDAWRPLWVVDFPMFEYDEDDKRWTACHHPFTSPKDEHVELLKTNPGECLAKAYDLA
CEECCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHE
LNGWEIGGGSVRIHRADVQATVFEALNIGAEEQQVKFGFLLDALKFGAPPHGGLAFGLDR
ECCEEECCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VVTMMAGAESIRDVIAFPKTQRAQCLLTNAPGEVDEKQLRELHIRLRQKVETQVEVGKA
HHHHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTQYCGQVTAAHLDQIVTLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHH
ESVRNEFVLKMTGKVRRRPAGTENANLTSGEIEVLCHEIEVLNTSATPPFQLDDENLSET
HHHHHHEEEEECCHHHCCCCCCCCCCCCCCHHHEEEEEHHEEECCCCCCCEECCCCHHHH
VRLTNRVIDLRRPQMQKNLMLRYKVAMAFRRFLDGAGFIDVETPMLTKSTPEGARDYLVP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHCCCC
SRVHPGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQVDIETSFL
CCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHC
NETEITALMEEMIRFVFKESLGVDLPSPFPRMTYAEAMRRYGSDKPDLRVTLELTEVTDL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHH
MKDVAFKVFSGPANSGGRVAAMRVPGGATLTRGEIDEYTKFVGIYGAKGLAYIKVNDASQ
HHHHHHHHCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHEECCCCEEEEEECCCCC
PNETGLQSPIVKNLSEAALRGVIERTGAQSGDLIFFGADKAKVVNDAIGALRIKLGHEKG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCEEEEEECCCCC
YVTGDAWRPLWVVDFPMFEYDEDDKRWTACHHPFTSPKDEHVELLKTNPGECLAKAYDLA
CEECCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHE
LNGWEIGGGSVRIHRADVQATVFEALNIGAEEQQVKFGFLLDALKFGAPPHGGLAFGLDR
ECCEEECCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VVTMMAGAESIRDVIAFPKTQRAQCLLTNAPGEVDEKQLRELHIRLRQKVETQVEVGKA
HHHHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA