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The map label for this gene is yjeP [H]

Identifier: 119899410

GI number: 119899410

Start: 3427710

End: 3429119

Strand: Reverse

Name: yjeP [H]

Synonym: azo3120

Alternate gene names: 119899410

Gene position: 3429119-3427710 (Counterclockwise)

Preceding gene: 119899411

Following gene: 119899409

Centisome position: 78.36

GC content: 68.94

Gene sequence:

>1410_bases
ATGCAGGACAACGCCCGCCCCGTCGAATTTGCCCGTTTGCTGCAGGACATCTGGGGCGACCTGCAGAACCCCGCAGTGCT
GTGGCAGATCGGCGCCTTGGTGGGCTGCCTGCTGCTCGGCTGGCTGATTCAGCGCCGCGCCCTGCGCCGCGCCGCGGCAG
CGCAGGGCGCCGAGGGGCAGGCCTACAGCGCCGCACGCCGCTTCGGCGAGCATGGCATGAAGCGGGTGATCTTTCCGCTC
TCGGCGCTGCTGCTGGTGGTGATGACGCGCGCGGTGCTGGTGCGTTACCACAACGCGTCGCTGCTGGATCTGGCGGTGCC
GCTGCTGGCCTCGCTGGCGCTGATCCGTTTCGTGGTGTTCACGCTGCGCCAGGCCGTCGGGCGTTCGAGCTGGCTAGGGG
CGTTCGAACGCGTGTTCGCGTCGCTCGCCTGGCTGGTGGTGGCGCTCCACATCGTCGGCTGGTTGCCGGAAGTCATCGAA
GGCCTGGAGTCGGTGTCGGTGACGCTGGGCAGCCAGAAGCTGTCGCTCTGGACGCTGCTGCTCGGCACGGCGATGGTGAT
GCTGACCGTGCTGGTGGCGATGTGGGCGGGTGGCGCGCTGGAGCGGCGGCTGGCCGCCGCGGCGGGGCTGGATTCCAATG
TGCGCGTCGTGCTCACGCGGGTGCTGCGCGCGCTGCTGCTGGTGATCGCGGTGCTGATCGCGCTGCCGATGGTGGGCATC
AACCTGACCACGCTGTCGGTGTTCGGCGGCGCGCTCGGTGTCGGCCTCGGCTTCGGCCTGCAGAAGATCGCGGCGAACTA
TGTCTCCGGCTTCATCCTGCTGCTCGACCGCTCGCTGCGGATCGGCAACCTGATCCGCGTCGGCAACGAGCGCGGCGTGG
TCAAGGAGATCAACACCCGCTACACGGTGATCCGCGCCGCCAACGGGGTGGAGTCGATCGTGCCGAACGAGACCCTGGTC
GCCTCGGTCGTGCAGAACGAGACCTTCACCGACAGCCTCGTTTCGCTGCCCCTGAACTTCCAGGTCGCCTACGACGCCGA
CGTGGAGCAGGCGATGCGGATTCTGGAGACGGTGGCGCAGCTGCAGCCGCGCGTGCTGCAAACGCCCGCGCCGCAGGCTT
TCCTGGTCGACTTCGGCGACAACGGCATCAACCTGCGGCTAAGCTGCTGGATCGGCGATCCCGCCGCCGGCACGCTCGGC
ATCACCTCGGCGATCAACATCGAGGTCTGGCGCCGCTTCAAGGCCGAAGGCATCGGTATCCCGTTTCCCCAGCGCGAGGT
CCGGCTGTTGCCGCCGCTGCCGGAACTGCCGCTGTCGGCGCCGGTCACAACAGCCACGCCGCCATCTTCGGCCGGCGACG
CGCAAGAGGTCCGAAAAGGCGGTTTGGCCGCCCCCGGCGGCTTCGCGTAG

Upstream 100 bases:

>100_bases
TGCGCGACAACTGCCCGGTTGCCCGCGCCTACCGCGACAACTGGCTGCGTCATCGCGCTCAGGCCGAACCCCTTACCCGT
TTGCCGTGGAAGCCCTGACC

Downstream 100 bases:

>100_bases
AATCGGCAAGCTTTTCTTCTGCAAGGAAATTTCAGCGCATGATCTCCGGGTTGTTCGATCTCCCGTGGTGGGGCTACATC
GTCGTCGCCCTCGTCCTGAC

Product: mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MQDNARPVEFARLLQDIWGDLQNPAVLWQIGALVGCLLLGWLIQRRALRRAAAAQGAEGQAYSAARRFGEHGMKRVIFPL
SALLLVVMTRAVLVRYHNASLLDLAVPLLASLALIRFVVFTLRQAVGRSSWLGAFERVFASLAWLVVALHIVGWLPEVIE
GLESVSVTLGSQKLSLWTLLLGTAMVMLTVLVAMWAGGALERRLAAAAGLDSNVRVVLTRVLRALLLVIAVLIALPMVGI
NLTTLSVFGGALGVGLGFGLQKIAANYVSGFILLLDRSLRIGNLIRVGNERGVVKEINTRYTVIRAANGVESIVPNETLV
ASVVQNETFTDSLVSLPLNFQVAYDADVEQAMRILETVAQLQPRVLQTPAPQAFLVDFGDNGINLRLSCWIGDPAAGTLG
ITSAINIEVWRRFKAEGIGIPFPQREVRLLPPLPELPLSAPVTTATPPSSAGDAQEVRKGGLAAPGGFA

Sequences:

>Translated_469_residues
MQDNARPVEFARLLQDIWGDLQNPAVLWQIGALVGCLLLGWLIQRRALRRAAAAQGAEGQAYSAARRFGEHGMKRVIFPL
SALLLVVMTRAVLVRYHNASLLDLAVPLLASLALIRFVVFTLRQAVGRSSWLGAFERVFASLAWLVVALHIVGWLPEVIE
GLESVSVTLGSQKLSLWTLLLGTAMVMLTVLVAMWAGGALERRLAAAAGLDSNVRVVLTRVLRALLLVIAVLIALPMVGI
NLTTLSVFGGALGVGLGFGLQKIAANYVSGFILLLDRSLRIGNLIRVGNERGVVKEINTRYTVIRAANGVESIVPNETLV
ASVVQNETFTDSLVSLPLNFQVAYDADVEQAMRILETVAQLQPRVLQTPAPQAFLVDFGDNGINLRLSCWIGDPAAGTLG
ITSAINIEVWRRFKAEGIGIPFPQREVRLLPPLPELPLSAPVTTATPPSSAGDAQEVRKGGLAAPGGFA
>Mature_469_residues
MQDNARPVEFARLLQDIWGDLQNPAVLWQIGALVGCLLLGWLIQRRALRRAAAAQGAEGQAYSAARRFGEHGMKRVIFPL
SALLLVVMTRAVLVRYHNASLLDLAVPLLASLALIRFVVFTLRQAVGRSSWLGAFERVFASLAWLVVALHIVGWLPEVIE
GLESVSVTLGSQKLSLWTLLLGTAMVMLTVLVAMWAGGALERRLAAAAGLDSNVRVVLTRVLRALLLVIAVLIALPMVGI
NLTTLSVFGGALGVGLGFGLQKIAANYVSGFILLLDRSLRIGNLIRVGNERGVVKEINTRYTVIRAANGVESIVPNETLV
ASVVQNETFTDSLVSLPLNFQVAYDADVEQAMRILETVAQLQPRVLQTPAPQAFLVDFGDNGINLRLSCWIGDPAAGTLG
ITSAINIEVWRRFKAEGIGIPFPQREVRLLPPLPELPLSAPVTTATPPSSAGDAQEVRKGGLAAPGGFA

Specific function: Unknown

COG id: COG3264

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=213, Percent_Identity=35.2112676056338, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1786670, Length=212, Percent_Identity=30.6603773584906, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789291, Length=247, Percent_Identity=25.5060728744939, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787591, Length=231, Percent_Identity=23.3766233766234, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 50354; Mature: 50354

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQDNARPVEFARLLQDIWGDLQNPAVLWQIGALVGCLLLGWLIQRRALRRAAAAQGAEGQ
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AYSAARRFGEHGMKRVIFPLSALLLVVMTRAVLVRYHNASLLDLAVPLLASLALIRFVVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TLRQAVGRSSWLGAFERVFASLAWLVVALHIVGWLPEVIEGLESVSVTLGSQKLSLWTLL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LGTAMVMLTVLVAMWAGGALERRLAAAAGLDSNVRVVLTRVLRALLLVIAVLIALPMVGI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLTTLSVFGGALGVGLGFGLQKIAANYVSGFILLLDRSLRIGNLIRVGNERGVVKEINTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHCCC
YTVIRAANGVESIVPNETLVASVVQNETFTDSLVSLPLNFQVAYDADVEQAMRILETVAQ
EEEEEECCCHHHHCCCHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
LQPRVLQTPAPQAFLVDFGDNGINLRLSCWIGDPAAGTLGITSAINIEVWRRFKAEGIGI
HCCHHHCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
PFPQREVRLLPPLPELPLSAPVTTATPPSSAGDAQEVRKGGLAAPGGFA
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]