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The map label for this gene is yhcS [C]

Identifier: 119899282

GI number: 119899282

Start: 3287206

End: 3288111

Strand: Direct

Name: yhcS [C]

Synonym: azo2992

Alternate gene names: 119899282

Gene position: 3287206-3288111 (Clockwise)

Preceding gene: 119899279

Following gene: 119899283

Centisome position: 75.12

GC content: 72.52

Gene sequence:

>906_bases
ATGGAGGATCTGAACGACCTCTACTACTACGTCCGGGTGGTCGACAACGGCGGCTTCGCGGCCGCCGGGCGCGCGCTCGG
GCTCCCTAAATCCAAGCTTAGCCGGCGCATCGCGCTGCTGGAGGAACGCCTCGGCGTGCGCCTGATCCAGCGCTCCACCC
GCCACTTCTCGGTCACCGAAATCGGCCAGACCTACTACGAGCATTGCCGCGCGATGCTGGTGGAGGCCGAAGCCGCGCGG
GAGGCCATCGAGCGCACCCGCGCCGAGCCGCGCGGGGTGGTGCGGATGAGCTGCCCGATCGCGATCCTGCACGCCCACGT
GGGCCGCATGCTGGCGGAGTTCCTGGCCGCGCATCCGCAGGTGGAGCTGCATCTGGAAGCGACCAACCGGCGGGTGTCGC
CACTCAACGAGGGCTTCGACCTCGCGCTGCGGGTGCGCCCGCCACCGCTGGCCGACAGCGACCTGGTGCTGCGCGTGCTG
TCCGACCGCAGCCAGTGCCTGGTGGCCAGCCCCGCGCTGATCGGCGCGCTCGGCGCCCCCGCCGCGCCGGCCGACCTCGA
CCGCTATCCCAGCCTCGCGCTCGGACCGCCGCAGGACGACCACCTGTGGACGCTGTACGGCCCGGACGCCGCGCAGGCCA
CGCTGCACCACCGGCCGCGGCTGATCACCAGCGACATGGTGGCGCTCAAGCGCGCGGCGCTGGCGGGTGTCGGCGTGGTG
CAGCTGCCGACCTTGATGGTGTGCGACGAACTCGCCGCCGGCAGCCTGGTACGCCTGCTGCCGCAGTGGGCGCCGCGGCG
CGAGATCATCCACGTGGTCTATCCCTCGCGCCGCGGCCTGCTGCCGGCGGTGCGGGCCTTGATCGACCACCTCGCCGCCG
CGTTCGGGGCACTGGACGAGGACTGA

Upstream 100 bases:

>100_bases
GGTAACAGCCTGGAAATCACTATAGAGATGCACCGCCGGCGCGATAAGACGGCAAAATCCGCTCTCAGCGTCCTATTCAT
GGAACAGTGAGGCGAGCGCG

Downstream 100 bases:

>100_bases
GGCGCGGCGGCTGGCGAACCCGCCCGCGCCCTGCCATCCTGAAGAAATCCCGTCTCAGGAGCCGCGCCATGACCCGCGTG
AGAGTCGAGAGCTTCGCCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MEDLNDLYYYVRVVDNGGFAAAGRALGLPKSKLSRRIALLEERLGVRLIQRSTRHFSVTEIGQTYYEHCRAMLVEAEAAR
EAIERTRAEPRGVVRMSCPIAILHAHVGRMLAEFLAAHPQVELHLEATNRRVSPLNEGFDLALRVRPPPLADSDLVLRVL
SDRSQCLVASPALIGALGAPAAPADLDRYPSLALGPPQDDHLWTLYGPDAAQATLHHRPRLITSDMVALKRAALAGVGVV
QLPTLMVCDELAAGSLVRLLPQWAPRREIIHVVYPSRRGLLPAVRALIDHLAAAFGALDED

Sequences:

>Translated_301_residues
MEDLNDLYYYVRVVDNGGFAAAGRALGLPKSKLSRRIALLEERLGVRLIQRSTRHFSVTEIGQTYYEHCRAMLVEAEAAR
EAIERTRAEPRGVVRMSCPIAILHAHVGRMLAEFLAAHPQVELHLEATNRRVSPLNEGFDLALRVRPPPLADSDLVLRVL
SDRSQCLVASPALIGALGAPAAPADLDRYPSLALGPPQDDHLWTLYGPDAAQATLHHRPRLITSDMVALKRAALAGVGVV
QLPTLMVCDELAAGSLVRLLPQWAPRREIIHVVYPSRRGLLPAVRALIDHLAAAFGALDED
>Mature_301_residues
MEDLNDLYYYVRVVDNGGFAAAGRALGLPKSKLSRRIALLEERLGVRLIQRSTRHFSVTEIGQTYYEHCRAMLVEAEAAR
EAIERTRAEPRGVVRMSCPIAILHAHVGRMLAEFLAAHPQVELHLEATNRRVSPLNEGFDLALRVRPPPLADSDLVLRVL
SDRSQCLVASPALIGALGAPAAPADLDRYPSLALGPPQDDHLWTLYGPDAAQATLHHRPRLITSDMVALKRAALAGVGVV
QLPTLMVCDELAAGSLVRLLPQWAPRREIIHVVYPSRRGLLPAVRALIDHLAAAFGALDED

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=28.8135593220339, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=30.7958477508651, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=27.891156462585, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=30.1694915254237, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787128, Length=300, Percent_Identity=26.3333333333333, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=25.4295532646048, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=26.5993265993266, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=124, Percent_Identity=29.8387096774194, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789173, Length=259, Percent_Identity=26.2548262548263, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI87082132, Length=273, Percent_Identity=25.6410256410256, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32968; Mature: 32968

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLNDLYYYVRVVDNGGFAAAGRALGLPKSKLSRRIALLEERLGVRLIQRSTRHFSVTE
CCCHHHEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IGQTYYEHCRAMLVEAEAAREAIERTRAEPRGVVRMSCPIAILHAHVGRMLAEFLAAHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
VELHLEATNRRVSPLNEGFDLALRVRPPPLADSDLVLRVLSDRSQCLVASPALIGALGAP
EEEEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEECCHHHHHCCCC
AAPADLDRYPSLALGPPQDDHLWTLYGPDAAQATLHHRPRLITSDMVALKRAALAGVGVV
CCCCCHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
QLPTLMVCDELAAGSLVRLLPQWAPRREIIHVVYPSRRGLLPAVRALIDHLAAAFGALDE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
D
C
>Mature Secondary Structure
MEDLNDLYYYVRVVDNGGFAAAGRALGLPKSKLSRRIALLEERLGVRLIQRSTRHFSVTE
CCCHHHEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IGQTYYEHCRAMLVEAEAAREAIERTRAEPRGVVRMSCPIAILHAHVGRMLAEFLAAHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
VELHLEATNRRVSPLNEGFDLALRVRPPPLADSDLVLRVLSDRSQCLVASPALIGALGAP
EEEEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEECCHHHHHCCCC
AAPADLDRYPSLALGPPQDDHLWTLYGPDAAQATLHHRPRLITSDMVALKRAALAGVGVV
CCCCCHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
QLPTLMVCDELAAGSLVRLLPQWAPRREIIHVVYPSRRGLLPAVRALIDHLAAAFGALDE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]