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The map label for this gene is tlpC [H]

Identifier: 119899271

GI number: 119899271

Start: 3274283

End: 3276310

Strand: Direct

Name: tlpC [H]

Synonym: azo2981

Alternate gene names: 119899271

Gene position: 3274283-3276310 (Clockwise)

Preceding gene: 119899270

Following gene: 119899274

Centisome position: 74.82

GC content: 68.0

Gene sequence:

>2028_bases
ATGGGACTGTTCACAAAACGCAATGGCAGCACTGGCAGCGGTGTCGTCACCCTTCAGGCGCGCGCCGCCGATCTCGACAC
CGTCCTCGCGCGCGCGGCGATCAAGCCGACCTTCGTCGCCGCCTTCGTGTCGCCGCATGTGGACATCGACCGCGTCGCCT
CAACCCTCTCCAGCCGCTTCCCCGGCGCGGCGCTGGCGCTGACCACCACCGCGGGCGAACTCTGCAGCGAAGGCGGCAGC
CGGCTCTACTGCGACACCGGCAACCACTGGGACCGCGTCGTCATCCAGTGCTTCGACGCCAGCATCATCGCGCGCGCCGA
GGTGGTCTCGATTCCGCTCGGCAGTGAAGACCTGCGCAGCGGCGGCAAGCCCGCCGAGCTGCACGAGCGCATCGCGCGGC
TTACCAGCAGCATCGCCAACACCCGGGTCGAGATGGACATCGACCACCGCGACACCCTCGCCTACGTGCTGTTCGACGGG
CTGTCGGCGTCCGAATCCTTCTTCATGGAAGCGCTCTACGAATCCGGCCGCTTCCCCTGTCTGTTCGTCGGCGGCTCGGC
CGGCGGCAAGCTGGATTTCGTCCGCACCGCGCTGCACGACGGCCGCCGCCAGCTGCAGAACCACGCCCTCGTCGTATTCC
TCAAGACCGCACCGGGCGCGCGCTTCGGCGTGTTCAAGAGCCAGAACTTCGAGCCCGCCGGGCTCTCCTTCCACGTGCTG
CACGCCTCGCTGGAACGCCGCCACGTCGGCCAGGTGATCACCTCCAGCGGCCGCATCCTGTCGATGGTGGATGCGCTGTG
CGAGGCGCTGAAATGCCGCGCCGAAGAACTCGACCAGAAGCTCGGCGACTACTCCTTCGCCATCCGCGTCGGCCAGGAAC
TGTTCGTGCGTTCGATCTCCAAGATCGACCTGCAGACCCGGCTGGTGCATTTCTACTGCGACATCGCCTCCGGCGAAGAG
ATCGTGCTGGTGCGCCGCACCGGCTTCGTCGACAGCACCGACCGCGACCTGCGCCGCTTCATGCAGGGCAAGCCGGGGCT
GCCGGTGGCCGGCATCATGAACGACTGCATCCTGCGCCGGCTCTACAACGACCGCGAACTCGCCGGCATCGACCGCCTGG
TGGCGGGCACCCAGATCGCCGGCTTCTCCACCTTCGGCGAAATCCTCGGCCTCAACCTCAACCAGACGCTGACCGCGGTG
TTCTTCTTCAAGGTGGCCGCCGGCGCGCGCTTCACCGACGAATACGTCGACAACTTCGTCGCCCACTACGGCGAGTTCAA
GGCCTTCTTCCTGCGCCGCCAGATCGGCAAGCTGGCTGGCCTGTCGCGCGTGATGCTGCAGCAGATCGAAGGCTACAAGG
CCGAACGTTTCGACGAAGCGCTCGACGCCGCCGACTTCGACGGCAGCTACGCGCCGGTGGTGCGCGGCCTCAACGACCTC
GGCGCCACCCTGCAGCACAGCCACGCGCTACGCCAGGCCACATCCCAGCAACTGGAAGCCTGCGCCACCGACCTCTACGC
CTCGGTGGACGGCCTCACCCGCCAGCTTGGGGAACAGGAAGGCGTCATCGCCAACGCCGGCGCCACCGTCGGCGACCTCA
CCCGCCAGGCCGGCAGCGTCGCCGCCAGCGCCCGCGCCCTGGCCGACGCCAGCGGCCGCATCCAGGGCGTGGTCCAGATC
ATCCAGCAGATCGCCGACCAGACCAACCTGCTCGCCCTCAACGCCGCCATCGAAGCGGCCCGCGCCGGCGAAGCCGGCCG
CGGCTTCGCGGTGGTGGCCGACGAAGTGCGCAAGCTCGCGGAGAAATCACGCACCAGCGCCGGCGAAATCGGCACCAGTA
TTTCTACCCTGGCAGGCGATATCGGCCGGGTGGCGCAGTCGATCGAAGGGCAGTCTGCGGACGTGGCGAATCTATCGGGG
ATGCTGGAGGCGATCCAGGCGTTCAGCGGGCAGACGGCGGAATCGGCGGGGCATACGCGGAGCGTGGCGGATACGTTGAG
GACGCTGACGCATGCGGGGGCGGATTGA

Upstream 100 bases:

>100_bases
GCCCCCCGCAACAACCATCAAGCCCGCCCTCACCTTGCCGATAAACCACAAACGGGCGTAACACCGCCGCGGTCCCCGAC
CGCAGCGCAGGAGAAAGCAC

Downstream 100 bases:

>100_bases
GGCGGGCCGCAAGTACACGTTGTCCACTTAGCGGGCTGACTCCCGACGTGGGCCAGCCCCCATAGCGCTGGCTTAGAAGT
CTTCTAGCAACTCGGCGACG

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MGLFTKRNGSTGSGVVTLQARAADLDTVLARAAIKPTFVAAFVSPHVDIDRVASTLSSRFPGAALALTTTAGELCSEGGS
RLYCDTGNHWDRVVIQCFDASIIARAEVVSIPLGSEDLRSGGKPAELHERIARLTSSIANTRVEMDIDHRDTLAYVLFDG
LSASESFFMEALYESGRFPCLFVGGSAGGKLDFVRTALHDGRRQLQNHALVVFLKTAPGARFGVFKSQNFEPAGLSFHVL
HASLERRHVGQVITSSGRILSMVDALCEALKCRAEELDQKLGDYSFAIRVGQELFVRSISKIDLQTRLVHFYCDIASGEE
IVLVRRTGFVDSTDRDLRRFMQGKPGLPVAGIMNDCILRRLYNDRELAGIDRLVAGTQIAGFSTFGEILGLNLNQTLTAV
FFFKVAAGARFTDEYVDNFVAHYGEFKAFFLRRQIGKLAGLSRVMLQQIEGYKAERFDEALDAADFDGSYAPVVRGLNDL
GATLQHSHALRQATSQQLEACATDLYASVDGLTRQLGEQEGVIANAGATVGDLTRQAGSVAASARALADASGRIQGVVQI
IQQIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKSRTSAGEIGTSISTLAGDIGRVAQSIEGQSADVANLSG
MLEAIQAFSGQTAESAGHTRSVADTLRTLTHAGAD

Sequences:

>Translated_675_residues
MGLFTKRNGSTGSGVVTLQARAADLDTVLARAAIKPTFVAAFVSPHVDIDRVASTLSSRFPGAALALTTTAGELCSEGGS
RLYCDTGNHWDRVVIQCFDASIIARAEVVSIPLGSEDLRSGGKPAELHERIARLTSSIANTRVEMDIDHRDTLAYVLFDG
LSASESFFMEALYESGRFPCLFVGGSAGGKLDFVRTALHDGRRQLQNHALVVFLKTAPGARFGVFKSQNFEPAGLSFHVL
HASLERRHVGQVITSSGRILSMVDALCEALKCRAEELDQKLGDYSFAIRVGQELFVRSISKIDLQTRLVHFYCDIASGEE
IVLVRRTGFVDSTDRDLRRFMQGKPGLPVAGIMNDCILRRLYNDRELAGIDRLVAGTQIAGFSTFGEILGLNLNQTLTAV
FFFKVAAGARFTDEYVDNFVAHYGEFKAFFLRRQIGKLAGLSRVMLQQIEGYKAERFDEALDAADFDGSYAPVVRGLNDL
GATLQHSHALRQATSQQLEACATDLYASVDGLTRQLGEQEGVIANAGATVGDLTRQAGSVAASARALADASGRIQGVVQI
IQQIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKSRTSAGEIGTSISTLAGDIGRVAQSIEGQSADVANLSG
MLEAIQAFSGQTAESAGHTRSVADTLRTLTHAGAD
>Mature_674_residues
GLFTKRNGSTGSGVVTLQARAADLDTVLARAAIKPTFVAAFVSPHVDIDRVASTLSSRFPGAALALTTTAGELCSEGGSR
LYCDTGNHWDRVVIQCFDASIIARAEVVSIPLGSEDLRSGGKPAELHERIARLTSSIANTRVEMDIDHRDTLAYVLFDGL
SASESFFMEALYESGRFPCLFVGGSAGGKLDFVRTALHDGRRQLQNHALVVFLKTAPGARFGVFKSQNFEPAGLSFHVLH
ASLERRHVGQVITSSGRILSMVDALCEALKCRAEELDQKLGDYSFAIRVGQELFVRSISKIDLQTRLVHFYCDIASGEEI
VLVRRTGFVDSTDRDLRRFMQGKPGLPVAGIMNDCILRRLYNDRELAGIDRLVAGTQIAGFSTFGEILGLNLNQTLTAVF
FFKVAAGARFTDEYVDNFVAHYGEFKAFFLRRQIGKLAGLSRVMLQQIEGYKAERFDEALDAADFDGSYAPVVRGLNDLG
ATLQHSHALRQATSQQLEACATDLYASVDGLTRQLGEQEGVIANAGATVGDLTRQAGSVAASARALADASGRIQGVVQII
QQIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKSRTSAGEIGTSISTLAGDIGRVAQSIEGQSADVANLSGM
LEAIQAFSGQTAESAGHTRSVADTLRTLTHAGAD

Specific function: Receptor For The Attractant L-Aspartate And Related Amino And Dicarboxylic Acids. Tar Also Mediates Taxis To The Attractant Maltose VIa An Interaction With The Periplasmic Maltose Binding Protein. Tar Mediates Taxis Away From The Repellents Cobalt And Ni

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=167, Percent_Identity=37.125748502994, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788194, Length=146, Percent_Identity=43.8356164383562, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789453, Length=126, Percent_Identity=39.6825396825397, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI2367378, Length=83, Percent_Identity=50.6024096385542, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787690, Length=99, Percent_Identity=47.4747474747475, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72293; Mature: 72161

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFTKRNGSTGSGVVTLQARAADLDTVLARAAIKPTFVAAFVSPHVDIDRVASTLSSRF
CCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCC
PGAALALTTTAGELCSEGGSRLYCDTGNHWDRVVIQCFDASIIARAEVVSIPLGSEDLRS
CCCEEEEECCHHHHHHCCCCEEEECCCCCHHHHHHHHHCHHHHHHEEEEECCCCCHHHHC
GGKPAELHERIARLTSSIANTRVEMDIDHRDTLAYVLFDGLSASESFFMEALYESGRFPC
CCCCHHHHHHHHHHHHHHHHCEEEEECCCCHHEEHHHHCCCCCHHHHHHHHHHHCCCCCE
LFVGGSAGGKLDFVRTALHDGRRQLQNHALVVFLKTAPGARFGVFKSQNFEPAGLSFHVL
EEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEHH
HASLERRHVGQVITSSGRILSMVDALCEALKCRAEELDQKLGDYSFAIRVGQELFVRSIS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KIDLQTRLVHFYCDIASGEEIVLVRRTGFVDSTDRDLRRFMQGKPGLPVAGIMNDCILRR
HHHHHHHHHHHEEEECCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
LYNDRELAGIDRLVAGTQIAGFSTFGEILGLNLNQTLTAVFFFKVAAGARFTDEYVDNFV
HCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
AHYGEFKAFFLRRQIGKLAGLSRVMLQQIEGYKAERFDEALDAADFDGSYAPVVRGLNDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHCHHHH
GATLQHSHALRQATSQQLEACATDLYASVDGLTRQLGEQEGVIANAGATVGDLTRQAGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
AASARALADASGRIQGVVQIIQQIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EKSRTSAGEIGTSISTLAGDIGRVAQSIEGQSADVANLSGMLEAIQAFSGQTAESAGHTR
HHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCHH
SVADTLRTLTHAGAD
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLFTKRNGSTGSGVVTLQARAADLDTVLARAAIKPTFVAAFVSPHVDIDRVASTLSSRF
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCC
PGAALALTTTAGELCSEGGSRLYCDTGNHWDRVVIQCFDASIIARAEVVSIPLGSEDLRS
CCCEEEEECCHHHHHHCCCCEEEECCCCCHHHHHHHHHCHHHHHHEEEEECCCCCHHHHC
GGKPAELHERIARLTSSIANTRVEMDIDHRDTLAYVLFDGLSASESFFMEALYESGRFPC
CCCCHHHHHHHHHHHHHHHHCEEEEECCCCHHEEHHHHCCCCCHHHHHHHHHHHCCCCCE
LFVGGSAGGKLDFVRTALHDGRRQLQNHALVVFLKTAPGARFGVFKSQNFEPAGLSFHVL
EEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEHH
HASLERRHVGQVITSSGRILSMVDALCEALKCRAEELDQKLGDYSFAIRVGQELFVRSIS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KIDLQTRLVHFYCDIASGEEIVLVRRTGFVDSTDRDLRRFMQGKPGLPVAGIMNDCILRR
HHHHHHHHHHHEEEECCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
LYNDRELAGIDRLVAGTQIAGFSTFGEILGLNLNQTLTAVFFFKVAAGARFTDEYVDNFV
HCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
AHYGEFKAFFLRRQIGKLAGLSRVMLQQIEGYKAERFDEALDAADFDGSYAPVVRGLNDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHCHHHH
GATLQHSHALRQATSQQLEACATDLYASVDGLTRQLGEQEGVIANAGATVGDLTRQAGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
AASARALADASGRIQGVVQIIQQIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EKSRTSAGEIGTSISTLAGDIGRVAQSIEGQSADVANLSGMLEAIQAFSGQTAESAGHTR
HHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCHH
SVADTLRTLTHAGAD
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]