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The map label for this gene is exaA2 [H]

Identifier: 119899262

GI number: 119899262

Start: 3261821

End: 3263698

Strand: Direct

Name: exaA2 [H]

Synonym: azo2972

Alternate gene names: 119899262

Gene position: 3261821-3263698 (Clockwise)

Preceding gene: 119899258

Following gene: 119899263

Centisome position: 74.54

GC content: 67.25

Gene sequence:

>1878_bases
ATGAGAACCAAGCAACCCGCGCCCCGGCTGCGCATGACCGTCGCCGCGCTCGCCGCCGCGCTTGCGCTGCCCGTCGCAGC
CGCCAGCAACGTCACGTGGGACGACATCGCCAACGACGACAAGACCACCGGCGACGTGCTGTCCTACGGCCTCGGCCTCA
AGGCGCAGCGCCACAGCACCTTGAAGCAGGTGAACACGAAGAACGTCGCCGGCCTGGTGCCGGCGTGGACCTTCTCCTTC
GGCGGCGAGAAGCAGCGCGGCCAGGAAGGCCAGGTGCTGGTGCATGACGGGGTGATCTACGCCACCGCGTCGTACTCGCG
CTTCTTCGCCATCGACGCCCGCAGCGGCAAGCGCCTGTGGGAATACGAGCATCGCCTGCCCGACGACATCCGCCCCTGCT
GCGACGTGGTCAACCGCGGCCCGGCGATCTACGGCGACAAGGTGTTCTTCGGCACGCTGGACGCCTCCATCGTCGCGCTC
GACAAGAACACCGGCAAGGTGGCGTGGAAGAAGAAGTTCGCCGACCACAAGGTCGGCTACACCATGACCGGCGCTCCCTT
CATCGTGAAGGACCAGAAGAGCGGCAAGATCCTGCTGGTGCACGGCTCCTCCGGCGACGAGTTCGGCGTGGTCGGCTGGC
TGTATGCGCGCGACCCGGACACCGGCGAGGAAGTGTGGGCGCGGCCGCTGGTCGAAGGCCACGTGGGCCGACTCAACGGC
AAGGACAGCACGCCCACCGGCGACGCCAAGGCGCCGTCGTGGCCGAACGACCCGAACTCCCCCACCGGCAAGGTCGAGGC
CTGGAGCCACGGCGGCGGCGCGCCCTGGCAGACCGCCAGCTTCGATGCCGAGAACAACACCATCGTCATCGGCGCCGGCA
ACCCCGCGCCGTGGAACACCTGGAAGCGCACCGCGCAGGGCGACGATCCGCAGAACTGGGACAACCTGTTCACCTCCGGC
CAGGCTTACGTGGATGCTAGCACCGGCGAGCTGAAGGGCTTCTACCAGCACACCCCGAACGACGCCTGGGACTTCTCCGG
CAACAACTCCATCATCCTGTTCGAATACAAGGACCCGAAGACCGGCAAGCAGGTAAAGGCCTCGGCGCATGCCGACCGCA
ACGGCTTCTTCTTCGTCACCGACCGCGACAAGCTCGCCAACGGCGCCGGCTACCCCAACAAGCCGACCTCGCTGATCGGC
GCCTGGCCCTTCGTCGATGGCATCACCTGGGCGTCGGGCTTCGACCTCAAGACCGGCAAGCCGATCGAGAAGGGCAACCG
GCCGCCCGCGCCCAAGGAAGGCGCCGACAAGGGCGACTCGGTGTTCGTCTCGCCGCCCTTCCTCGGCGGCACCAACTGGC
ATCCGATGTCGTACAGCCCGGACACCGGCCTGTTCTACATCCCGGCCAACCACTGGGCGATGGACTACTGGACCGAGCAC
CTGACCTACAAGGCCGGCTCCGCCTATCTCGGTCAGGGCTTCCGCATCAAGCGCCTGTTCGACGACCACGTCGGCGTGCT
GCGCGCGATCGACCCCAAGAGCGGCAAGATCGCCTGGGAGCACAAGGAGAAATTCCCGCTGTGGGCCGGCACGCTGACCA
CCGCCGGCGGGCTGATCTTCACCGGCACCTCGGACGGCTACGTGAAGGCCTTCGACGCGAAGAACGGCAAGGAGCTGTGG
TCCTTCCAGACCGGTTCCGGCGTGGTCTCGGTGCCGGTGACCTGGGAGATGGACGGCGAGCAGTACATCGGCATCCAGTC
CGGCTACGGTGGCGCGGTGCCGCTGTGGGGCGGCGACATGGCCGACCTCACCAAGCAGGTCACCCAGGGCGGTTCGATGT
GGGTGTTCAAGCTGCCCCGGCAGGTGGCCAGCAAGTAA

Upstream 100 bases:

>100_bases
CCCGCGACCGCCGCCGCGGCCGGCCGACATACTGCGGCCGCCATCCGGAGCCGGGCCCACCCGCCTCCGATGCCCATCAC
ACAGGAGGCAAGGAGCCACA

Downstream 100 bases:

>100_bases
GCCCCAGAGGCAGGCCCAAGGCGGTCCGGCGGCAACGCCGGGCCGCACTCCGCCAACCGCCCGCGGCGCCTCCCCGCCGC
GGGCACTCACACCCGAACCG

Product: ExaA2 protein

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MRTKQPAPRLRMTVAALAAALALPVAAASNVTWDDIANDDKTTGDVLSYGLGLKAQRHSTLKQVNTKNVAGLVPAWTFSF
GGEKQRGQEGQVLVHDGVIYATASYSRFFAIDARSGKRLWEYEHRLPDDIRPCCDVVNRGPAIYGDKVFFGTLDASIVAL
DKNTGKVAWKKKFADHKVGYTMTGAPFIVKDQKSGKILLVHGSSGDEFGVVGWLYARDPDTGEEVWARPLVEGHVGRLNG
KDSTPTGDAKAPSWPNDPNSPTGKVEAWSHGGGAPWQTASFDAENNTIVIGAGNPAPWNTWKRTAQGDDPQNWDNLFTSG
QAYVDASTGELKGFYQHTPNDAWDFSGNNSIILFEYKDPKTGKQVKASAHADRNGFFFVTDRDKLANGAGYPNKPTSLIG
AWPFVDGITWASGFDLKTGKPIEKGNRPPAPKEGADKGDSVFVSPPFLGGTNWHPMSYSPDTGLFYIPANHWAMDYWTEH
LTYKAGSAYLGQGFRIKRLFDDHVGVLRAIDPKSGKIAWEHKEKFPLWAGTLTTAGGLIFTGTSDGYVKAFDAKNGKELW
SFQTGSGVVSVPVTWEMDGEQYIGIQSGYGGAVPLWGGDMADLTKQVTQGGSMWVFKLPRQVASK

Sequences:

>Translated_625_residues
MRTKQPAPRLRMTVAALAAALALPVAAASNVTWDDIANDDKTTGDVLSYGLGLKAQRHSTLKQVNTKNVAGLVPAWTFSF
GGEKQRGQEGQVLVHDGVIYATASYSRFFAIDARSGKRLWEYEHRLPDDIRPCCDVVNRGPAIYGDKVFFGTLDASIVAL
DKNTGKVAWKKKFADHKVGYTMTGAPFIVKDQKSGKILLVHGSSGDEFGVVGWLYARDPDTGEEVWARPLVEGHVGRLNG
KDSTPTGDAKAPSWPNDPNSPTGKVEAWSHGGGAPWQTASFDAENNTIVIGAGNPAPWNTWKRTAQGDDPQNWDNLFTSG
QAYVDASTGELKGFYQHTPNDAWDFSGNNSIILFEYKDPKTGKQVKASAHADRNGFFFVTDRDKLANGAGYPNKPTSLIG
AWPFVDGITWASGFDLKTGKPIEKGNRPPAPKEGADKGDSVFVSPPFLGGTNWHPMSYSPDTGLFYIPANHWAMDYWTEH
LTYKAGSAYLGQGFRIKRLFDDHVGVLRAIDPKSGKIAWEHKEKFPLWAGTLTTAGGLIFTGTSDGYVKAFDAKNGKELW
SFQTGSGVVSVPVTWEMDGEQYIGIQSGYGGAVPLWGGDMADLTKQVTQGGSMWVFKLPRQVASK
>Mature_625_residues
MRTKQPAPRLRMTVAALAAALALPVAAASNVTWDDIANDDKTTGDVLSYGLGLKAQRHSTLKQVNTKNVAGLVPAWTFSF
GGEKQRGQEGQVLVHDGVIYATASYSRFFAIDARSGKRLWEYEHRLPDDIRPCCDVVNRGPAIYGDKVFFGTLDASIVAL
DKNTGKVAWKKKFADHKVGYTMTGAPFIVKDQKSGKILLVHGSSGDEFGVVGWLYARDPDTGEEVWARPLVEGHVGRLNG
KDSTPTGDAKAPSWPNDPNSPTGKVEAWSHGGGAPWQTASFDAENNTIVIGAGNPAPWNTWKRTAQGDDPQNWDNLFTSG
QAYVDASTGELKGFYQHTPNDAWDFSGNNSIILFEYKDPKTGKQVKASAHADRNGFFFVTDRDKLANGAGYPNKPTSLIG
AWPFVDGITWASGFDLKTGKPIEKGNRPPAPKEGADKGDSVFVSPPFLGGTNWHPMSYSPDTGLFYIPANHWAMDYWTEH
LTYKAGSAYLGQGFRIKRLFDDHVGVLRAIDPKSGKIAWEHKEKFPLWAGTLTTAGGLIFTGTSDGYVKAFDAKNGKELW
SFQTGSGVVSVPVTWEMDGEQYIGIQSGYGGAVPLWGGDMADLTKQVTQGGSMWVFKLPRQVASK

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=385, Percent_Identity=24.1558441558442, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 67982; Mature: 67982

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTKQPAPRLRMTVAALAAALALPVAAASNVTWDDIANDDKTTGDVLSYGLGLKAQRHST
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHCCCCCHHHHHH
LKQVNTKNVAGLVPAWTFSFGGEKQRGQEGQVLVHDGVIYATASYSRFFAIDARSGKRLW
HHHCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCEEEEEECCEEEEEEECCCCCHHH
EYEHRLPDDIRPCCDVVNRGPAIYGDKVFFGTLDASIVALDKNTGKVAWKKKFADHKVGY
HHHHCCCHHHHHHHHHHHCCCCEECCEEEEEECCEEEEEEECCCCCEEEEHHCCCCCCCE
TMTGAPFIVKDQKSGKILLVHGSSGDEFGVVGWLYARDPDTGEEVWARPLVEGHVGRLNG
EECCCCEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEECCC
KDSTPTGDAKAPSWPNDPNSPTGKVEAWSHGGGAPWQTASFDAENNTIVIGAGNPAPWNT
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEECCCCCEEEEECCCCCCCHH
WKRTAQGDDPQNWDNLFTSGQAYVDASTGELKGFYQHTPNDAWDFSGNNSIILFEYKDPK
HHHCCCCCCCCCHHHHHCCCCEEEECCCCCCCCCEECCCCCCCCCCCCCEEEEEEECCCC
TGKQVKASAHADRNGFFFVTDRDKLANGAGYPNKPTSLIGAWPFVDGITWASGFDLKTGK
CCCEEEECCCCCCCCEEEEECHHHHCCCCCCCCCCCCEEECCHHHCCCCCCCCCCCCCCC
PIEKGNRPPAPKEGADKGDSVFVSPPFLGGTNWHPMSYSPDTGLFYIPANHWAMDYWTEH
CHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHH
LTYKAGSAYLGQGFRIKRLFDDHVGVLRAIDPKSGKIAWEHKEKFPLWAGTLTTAGGLIF
HEEECCCHHHCCCEEEEEHHHCCCCEEEEECCCCCCEEEECCCCCCEEEEHHHHCCCEEE
TGTSDGYVKAFDAKNGKELWSFQTGSGVVSVPVTWEMDGEQYIGIQSGYGGAVPLWGGDM
ECCCCCEEEEEECCCCCEEEEEECCCCEEEEEEEEEECCCEEEEEECCCCCEEECCCCCH
ADLTKQVTQGGSMWVFKLPRQVASK
HHHHHHHHCCCCEEEEECCHHHHCC
>Mature Secondary Structure
MRTKQPAPRLRMTVAALAAALALPVAAASNVTWDDIANDDKTTGDVLSYGLGLKAQRHST
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHCCCCCHHHHHH
LKQVNTKNVAGLVPAWTFSFGGEKQRGQEGQVLVHDGVIYATASYSRFFAIDARSGKRLW
HHHCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCEEEEEECCEEEEEEECCCCCHHH
EYEHRLPDDIRPCCDVVNRGPAIYGDKVFFGTLDASIVALDKNTGKVAWKKKFADHKVGY
HHHHCCCHHHHHHHHHHHCCCCEECCEEEEEECCEEEEEEECCCCCEEEEHHCCCCCCCE
TMTGAPFIVKDQKSGKILLVHGSSGDEFGVVGWLYARDPDTGEEVWARPLVEGHVGRLNG
EECCCCEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEECCC
KDSTPTGDAKAPSWPNDPNSPTGKVEAWSHGGGAPWQTASFDAENNTIVIGAGNPAPWNT
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEECCCCCEEEEECCCCCCCHH
WKRTAQGDDPQNWDNLFTSGQAYVDASTGELKGFYQHTPNDAWDFSGNNSIILFEYKDPK
HHHCCCCCCCCCHHHHHCCCCEEEECCCCCCCCCEECCCCCCCCCCCCCEEEEEEECCCC
TGKQVKASAHADRNGFFFVTDRDKLANGAGYPNKPTSLIGAWPFVDGITWASGFDLKTGK
CCCEEEECCCCCCCCEEEEECHHHHCCCCCCCCCCCCEEECCHHHCCCCCCCCCCCCCCC
PIEKGNRPPAPKEGADKGDSVFVSPPFLGGTNWHPMSYSPDTGLFYIPANHWAMDYWTEH
CHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHH
LTYKAGSAYLGQGFRIKRLFDDHVGVLRAIDPKSGKIAWEHKEKFPLWAGTLTTAGGLIF
HEEECCCHHHCCCEEEEEHHHCCCCEEEEECCCCCCEEEECCCCCCEEEEHHHHCCCEEE
TGTSDGYVKAFDAKNGKELWSFQTGSGVVSVPVTWEMDGEQYIGIQSGYGGAVPLWGGDM
ECCCCCEEEEEECCCCCEEEEEECCCCEEEEEEEEEECCCEEEEEECCCCCEEECCCCCH
ADLTKQVTQGGSMWVFKLPRQVASK
HHHHHHHHCCCCEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]