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The map label for this gene is uvrY [H]

Identifier: 119899260

GI number: 119899260

Start: 3259643

End: 3260290

Strand: Reverse

Name: uvrY [H]

Synonym: azo2970

Alternate gene names: 119899260

Gene position: 3260290-3259643 (Counterclockwise)

Preceding gene: 119899261

Following gene: 119899259

Centisome position: 74.5

GC content: 70.83

Gene sequence:

>648_bases
ATGATCCGCATCCTGCTGCTCGACGACCATGCCGTGGTGCGTACCGGCTACCGCCGCCTGATCGACGCCGAGCCCGGCCT
GCAGGTGGTGGCCGAGGCCGCCACCGCCGACGAGGCCTATGCGTGCGTGGTGGGCGGCGGCATCGACGTCGCGGTGGTGG
ATCTCAGCCTGCGGGGCGCCAGCGGCATCGAGGCCATCCGCCGCATGCTGGCGCGCGACCCCGGCCTGCGCGTGCTGGTG
CTGTCGATGCACGACAGCCCGGGCTACGCCACCCAGGCGATGCGCGCCGGCGCGCTCGGCTATCTCACCAAGAACAGCGA
ACCGGACGAGATGCTGGACGCGATCCGCGCGGTGGCGGCGGGCCGGCGCGTGCTGTCGGCGGAGATTGCGCAGGCGCTGG
CCGGCGCCGCGCTCGACGGCGAACAACTGCTGACGCGGCTGACCCCGCGCGAATTCGAGGTGCTGCGCATGGCCGCCAGC
GGCGAACCCGCCGCCTGTATCGCCGACCGCATGCACCTTAGCCAGAAGACGGTGCTCAACCACCTCTCGGCGATCCGGCA
GAAGCTGGATGCCGACAACGATTTCAAATTGCTCAGGCTGGCTGCGCGCCACGGCCTGGTAGACCTGGGGGCCGAAGCCA
TGTGCTGA

Upstream 100 bases:

>100_bases
CCGCAATGGCGGGCGGCGAGTTCCGCCTGGAAGACCGCCCCGGCGGCGGATTGGTGACCCTGCTGCGCCTGACTACGATG
AACGGGAAGGAGGCCCCGCG

Downstream 100 bases:

>100_bases
GGCGACCCGAATGCGCGCGTGTTGCTGTTCCGATCCGTAACGCTGGAGATGAGAAAAATGAGTCACACGATCCGCTACCG
CATGCTCCTCGCTGCGCTGT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIRILLLDDHAVVRTGYRRLIDAEPGLQVVAEAATADEAYACVVGGGIDVAVVDLSLRGASGIEAIRRMLARDPGLRVLV
LSMHDSPGYATQAMRAGALGYLTKNSEPDEMLDAIRAVAAGRRVLSAEIAQALAGAALDGEQLLTRLTPREFEVLRMAAS
GEPAACIADRMHLSQKTVLNHLSAIRQKLDADNDFKLLRLAARHGLVDLGAEAMC

Sequences:

>Translated_215_residues
MIRILLLDDHAVVRTGYRRLIDAEPGLQVVAEAATADEAYACVVGGGIDVAVVDLSLRGASGIEAIRRMLARDPGLRVLV
LSMHDSPGYATQAMRAGALGYLTKNSEPDEMLDAIRAVAAGRRVLSAEIAQALAGAALDGEQLLTRLTPREFEVLRMAAS
GEPAACIADRMHLSQKTVLNHLSAIRQKLDADNDFKLLRLAARHGLVDLGAEAMC
>Mature_215_residues
MIRILLLDDHAVVRTGYRRLIDAEPGLQVVAEAATADEAYACVVGGGIDVAVVDLSLRGASGIEAIRRMLARDPGLRVLV
LSMHDSPGYATQAMRAGALGYLTKNSEPDEMLDAIRAVAAGRRVLSAEIAQALAGAALDGEQLLTRLTPREFEVLRMAAS
GEPAACIADRMHLSQKTVLNHLSAIRQKLDADNDFKLLRLAARHGLVDLGAEAMC

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=33.6492890995261, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=39.1959798994975, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788521, Length=191, Percent_Identity=32.9842931937173, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=32.7868852459016, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=25.3658536585366, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=26.3414634146341, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788712, Length=202, Percent_Identity=23.2673267326733, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22935; Mature: 22935

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRILLLDDHAVVRTGYRRLIDAEPGLQVVAEAATADEAYACVVGGGIDVAVVDLSLRGA
CEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCC
SGIEAIRRMLARDPGLRVLVLSMHDSPGYATQAMRAGALGYLTKNSEPDEMLDAIRAVAA
CHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCHHEEECCCCCHHHHHHHHHHHHH
GRRVLSAEIAQALAGAALDGEQLLTRLTPREFEVLRMAASGEPAACIADRMHLSQKTVLN
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
HLSAIRQKLDADNDFKLLRLAARHGLVDLGAEAMC
HHHHHHHHHCCCCCHHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure
MIRILLLDDHAVVRTGYRRLIDAEPGLQVVAEAATADEAYACVVGGGIDVAVVDLSLRGA
CEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCC
SGIEAIRRMLARDPGLRVLVLSMHDSPGYATQAMRAGALGYLTKNSEPDEMLDAIRAVAA
CHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCHHEEECCCCCHHHHHHHHHHHHH
GRRVLSAEIAQALAGAALDGEQLLTRLTPREFEVLRMAASGEPAACIADRMHLSQKTVLN
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
HLSAIRQKLDADNDFKLLRLAARHGLVDLGAEAMC
HHHHHHHHHCCCCCHHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]