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The map label for this gene is purC

Identifier: 119899163

GI number: 119899163

Start: 3152720

End: 3153655

Strand: Direct

Name: purC

Synonym: azo2873

Alternate gene names: 119899163

Gene position: 3152720-3153655 (Clockwise)

Preceding gene: 119899162

Following gene: 119899166

Centisome position: 72.05

GC content: 68.48

Gene sequence:

>936_bases
GTGGCCACCCCGCTTTTCGAATCCACCATCAAGAGTCTGCCGCTGCTCGGGCGCGGCAAGGTCCGCGATATCTACGCCGT
CGACGCCGACAAGCTGCTGATCGTCACCAGCGACCGGCTGTCCGCCTTCGACGTGATCCTGCCCAACCCGATCCCCGACA
AGGGCCGCGTGCTCACCGCGATGGCCAACTTCTGGTTCGCCAAGCTCGGCCACATCGTCCCCAACCAGCTCACCGGCATC
GATCCGGAATCGGTGGTCGCCGCCGACGAGCGCGAGCAGGTCAAGGGCCGCGCGCTGGTGGTCAAGCGCCTCAAGCCGCT
GCCGATCGAGGCGGTGGTGCGCGGCTACGTCATTGGCTCCGGCTGGAAGGACTACCAGGACACCGGCGCGATCTGCGGCA
TCGCCTTGCCCGCGGGGCTCAAGCAGGCAGCCAAGCTGCCGGCGCCCATCTTCACCCCGGCCTCCAAGGCCGAAGTCGGC
GATCACGACGAGAACATCTCCTTCGCCCAGGCGCAGGCGAACTGCGACGCGGTGCTCGCCGAAGCGCTCGCCGGCACCGG
CAAGACTGGCGCCGGGCTGGCCGAGGAAGCCCGCCAGGCCGCGATCGCGCTGTACAGCCAGGCAGCCGACTATGCCGCCG
GCCGCGGCATCATCATCGCCGACACCAAGTTCGAGTTCGGCATCGACGCCGCCGGCACCCTGCACCTGATCGACGAGGCG
CTGACGCCGGATTCGTCCCGTTTCTGGCCGGCCGACAGCTACCGCGAGGGCATCAGCCCGCCGTCCTACGACAAGCAGTA
CGTGCGCGACTATCTGGAAACGCTGGACTGGAACAAGAAGGCGCCGGGCCCCGACCTGCCCGCCGACGTCGTCGAGCGCA
CCGCGGCCAAGTACCGCGAAGCCTACGAAAAGCTCACCGGCCTGACGCTGGCCTGA

Upstream 100 bases:

>100_bases
AGCAGAGCTTGCCGAAACCCCGGCCAAACCCCCTTGAAGGGAGAGGAGTAAAAGCAGCGCGCTCACCTATAATCGCGTTT
TGCTCTCAGAGACCCCTTCC

Downstream 100 bases:

>100_bases
GCCGGCGCACCGCCCGGCCACGCCGCCCGCGCCCTGTGCGCCGGCGGCGTTTTTCATTTCGGCGTGGCGCTCAGTCGTGA
AAGGCGAAGGTCCAGCGCTC

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MATPLFESTIKSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFDVILPNPIPDKGRVLTAMANFWFAKLGHIVPNQLTGI
DPESVVAADEREQVKGRALVVKRLKPLPIEAVVRGYVIGSGWKDYQDTGAICGIALPAGLKQAAKLPAPIFTPASKAEVG
DHDENISFAQAQANCDAVLAEALAGTGKTGAGLAEEARQAAIALYSQAADYAAGRGIIIADTKFEFGIDAAGTLHLIDEA
LTPDSSRFWPADSYREGISPPSYDKQYVRDYLETLDWNKKAPGPDLPADVVERTAAKYREAYEKLTGLTLA

Sequences:

>Translated_311_residues
MATPLFESTIKSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFDVILPNPIPDKGRVLTAMANFWFAKLGHIVPNQLTGI
DPESVVAADEREQVKGRALVVKRLKPLPIEAVVRGYVIGSGWKDYQDTGAICGIALPAGLKQAAKLPAPIFTPASKAEVG
DHDENISFAQAQANCDAVLAEALAGTGKTGAGLAEEARQAAIALYSQAADYAAGRGIIIADTKFEFGIDAAGTLHLIDEA
LTPDSSRFWPADSYREGISPPSYDKQYVRDYLETLDWNKKAPGPDLPADVVERTAAKYREAYEKLTGLTLA
>Mature_310_residues
ATPLFESTIKSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFDVILPNPIPDKGRVLTAMANFWFAKLGHIVPNQLTGID
PESVVAADEREQVKGRALVVKRLKPLPIEAVVRGYVIGSGWKDYQDTGAICGIALPAGLKQAAKLPAPIFTPASKAEVGD
HDENISFAQAQANCDAVLAEALAGTGKTGAGLAEEARQAAIALYSQAADYAAGRGIIIADTKFEFGIDAAGTLHLIDEAL
TPDSSRFWPADSYREGISPPSYDKQYVRDYLETLDWNKKAPGPDLPADVVERTAAKYREAYEKLTGLTLA

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=305, Percent_Identity=48.5245901639344, Blast_Score=277, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR7_AZOSB (A1K9I4)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934376.1
- ProteinModelPortal:   A1K9I4
- SMR:   A1K9I4
- STRING:   A1K9I4
- GeneID:   4607664
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2873
- eggNOG:   COG0152
- HOGENOM:   HBG555040
- OMA:   LTLMDEV
- PhylomeDB:   A1K9I4
- ProtClustDB:   PRK13961
- BioCyc:   ASP62928:AZO2873-MONOMER
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609
- TIGRFAMs:   TIGR00081

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 33366; Mature: 33235

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPLFESTIKSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFDVILPNPIPDKGRVLTA
CCCCHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHH
MANFWFAKLGHIVPNQLTGIDPESVVAADEREQVKGRALVVKRLKPLPIEAVVRGYVIGS
HHHHHHHHHHHHCCCHHCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHEECC
GWKDYQDTGAICGIALPAGLKQAAKLPAPIFTPASKAEVGDHDENISFAQAQANCDAVLA
CCCCHHHCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EALAGTGKTGAGLAEEARQAAIALYSQAADYAAGRGIIIADTKFEFGIDAAGTLHLIDEA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCCHHHHHHHH
LTPDSSRFWPADSYREGISPPSYDKQYVRDYLETLDWNKKAPGPDLPADVVERTAAKYRE
CCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
AYEKLTGLTLA
HHHHHHCCCCC
>Mature Secondary Structure 
ATPLFESTIKSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFDVILPNPIPDKGRVLTA
CCCHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHH
MANFWFAKLGHIVPNQLTGIDPESVVAADEREQVKGRALVVKRLKPLPIEAVVRGYVIGS
HHHHHHHHHHHHCCCHHCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHEECC
GWKDYQDTGAICGIALPAGLKQAAKLPAPIFTPASKAEVGDHDENISFAQAQANCDAVLA
CCCCHHHCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EALAGTGKTGAGLAEEARQAAIALYSQAADYAAGRGIIIADTKFEFGIDAAGTLHLIDEA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCCHHHHHHHH
LTPDSSRFWPADSYREGISPPSYDKQYVRDYLETLDWNKKAPGPDLPADVVERTAAKYRE
CCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
AYEKLTGLTLA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA