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The map label for this gene is rpiA

Identifier: 119899116

GI number: 119899116

Start: 3104643

End: 3105311

Strand: Direct

Name: rpiA

Synonym: azo2826

Alternate gene names: 119899116

Gene position: 3104643-3105311 (Clockwise)

Preceding gene: 119899115

Following gene: 119899117

Centisome position: 70.95

GC content: 67.26

Gene sequence:

>669_bases
ATGACCCAGGACGAACTCAAGAAAGCCGCCGCCCTCGCCGCACTCGACTATGTGGAGGACGGAATGATCGTCGGCGTCGG
CACCGGCTCGACGGTGAACCACTTCATCGACGGGCTGGCCGGCATCAAGCACCGTATCCGCGGCGCCGTCTCCAGTTCCG
AGGCCAGCTCCAAACGCCTTGCCGCGCATGGCATTGCGCTGCTCGACCTCAACGACGTGGACGAACTGCCGGTGTATATC
GACGGCGCGGACGAAATCGACCACGGCTTCGCGATGATCAAGGGCGGCGGCGGCGCGCTCACGCGCGAGAAGATCGTCGC
TGCGGTCGCACGCCGCTTTGTCTGCATCTGCGACGAATCCAAGCGGGTGGACGTACTGGGCCGCTTTCCGCTGCCGATCG
AGGTCATCCCGATGGCGCGCAGCCAGGTGATGCGTGCGGCGGCAGCGCTGGGCGCGACGCCGCGGCTGCGCGAGGGCTTC
GTGACCGACAACGGCAACCTGATCATCGACCTCCATGGCCTGTCGATCACCGACCCGTGCGCAACCGAGCAGGCCCTGAA
CGCGGTCGTGGGCGTGGTCACCAACGGCCTGTTCGCGGCGCGCGGTGCCGACACCCTGCTGCTGGCCAGCGCCCAAGGCG
TGCGCCGGTTCGAGCGTTCCGCAACATAA

Upstream 100 bases:

>100_bases
GCGTCGCTGCCGGCGATCTCGTTCTGGTGCAGCCTTTCGACGGTCTCGTCTGACCGGCCACCGCACACACCTCTCGTATG
CCACTTTTCCGAGCGAACAC

Downstream 100 bases:

>100_bases
CCGTAACCCGGGCCTGCTAGCCTGCCCCACTTCTGGATAGTGCCATGGCAAAAATGAGCGAACACACGTACAGACAGTTC
GATGCCGAACTGGAGGCAAT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTQDELKKAAALAALDYVEDGMIVGVGTGSTVNHFIDGLAGIKHRIRGAVSSSEASSKRLAAHGIALLDLNDVDELPVYI
DGADEIDHGFAMIKGGGGALTREKIVAAVARRFVCICDESKRVDVLGRFPLPIEVIPMARSQVMRAAAALGATPRLREGF
VTDNGNLIIDLHGLSITDPCATEQALNAVVGVVTNGLFAARGADTLLLASAQGVRRFERSAT

Sequences:

>Translated_222_residues
MTQDELKKAAALAALDYVEDGMIVGVGTGSTVNHFIDGLAGIKHRIRGAVSSSEASSKRLAAHGIALLDLNDVDELPVYI
DGADEIDHGFAMIKGGGGALTREKIVAAVARRFVCICDESKRVDVLGRFPLPIEVIPMARSQVMRAAAALGATPRLREGF
VTDNGNLIIDLHGLSITDPCATEQALNAVVGVVTNGLFAARGADTLLLASAQGVRRFERSAT
>Mature_221_residues
TQDELKKAAALAALDYVEDGMIVGVGTGSTVNHFIDGLAGIKHRIRGAVSSSEASSKRLAAHGIALLDLNDVDELPVYID
GADEIDHGFAMIKGGGGALTREKIVAAVARRFVCICDESKRVDVLGRFPLPIEVIPMARSQVMRAAAALGATPRLREGFV
TDNGNLIIDLHGLSITDPCATEQALNAVVGVVTNGLFAARGADTLLLASAQGVRRFERSAT

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=212, Percent_Identity=36.7924528301887, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1789280, Length=219, Percent_Identity=60.7305936073059, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17551758, Length=229, Percent_Identity=38.4279475982533, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324669, Length=224, Percent_Identity=30.3571428571429, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364072, Length=200, Percent_Identity=33.5, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_AZOSB (A1K9D7)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934329.1
- ProteinModelPortal:   A1K9D7
- SMR:   A1K9D7
- STRING:   A1K9D7
- GeneID:   4609258
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2826
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- PhylomeDB:   A1K9D7
- ProtClustDB:   PRK00702
- BioCyc:   ASP62928:AZO2826-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23290; Mature: 23159

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKKAAALAALDYVEDGMIVGVGTGSTVNHFIDGLAGIKHRIRGAVSSSEASSKRL
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AAHGIALLDLNDVDELPVYIDGADEIDHGFAMIKGGGGALTREKIVAAVARRFVCICDES
HHCCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEECCC
KRVDVLGRFPLPIEVIPMARSQVMRAAAALGATPRLREGFVTDNGNLIIDLHGLSITDPC
CCEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCHHCCEEECCCCEEEEECCCCCCCCC
ATEQALNAVVGVVTNGLFAARGADTLLLASAQGVRRFERSAT
HHHHHHHHHHHHHHCCEEEECCCCEEEEECHHHHHHHHHCCC
>Mature Secondary Structure 
TQDELKKAAALAALDYVEDGMIVGVGTGSTVNHFIDGLAGIKHRIRGAVSSSEASSKRL
CHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AAHGIALLDLNDVDELPVYIDGADEIDHGFAMIKGGGGALTREKIVAAVARRFVCICDES
HHCCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEECCC
KRVDVLGRFPLPIEVIPMARSQVMRAAAALGATPRLREGFVTDNGNLIIDLHGLSITDPC
CCEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCHHCCEEECCCCEEEEECCCCCCCCC
ATEQALNAVVGVVTNGLFAARGADTLLLASAQGVRRFERSAT
HHHHHHHHHHHHHHCCEEEECCCCEEEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA