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The map label for this gene is bioC2 [C]

Identifier: 119899108

GI number: 119899108

Start: 3097630

End: 3098547

Strand: Direct

Name: bioC2 [C]

Synonym: azo2818

Alternate gene names: 119899108

Gene position: 3097630-3098547 (Clockwise)

Preceding gene: 119899107

Following gene: 119899109

Centisome position: 70.79

GC content: 72.11

Gene sequence:

>918_bases
ATGGCCGCGGCCGACACCGACTTCCACCTCGACCGCGCCCTGCTGCGGCGGCGCTTCGCGGCCGCAGCAGGGCGCTACGA
CGAGGCCGACGTCCTGGCGCGCGAAATCGCGCGCCGCATGGACGAGCGCCTCGACTACATCCGCCACAGCCCGCGCCGTA
TCCTCGACCTGGGCTGCGGCACCGGCGCCGACCTGCCGCGCCTGGCCGAACGCTACCCTGAGGCCCATCTCGTCGCAGCC
GATTTCGCTGCCCCCATGGCCTCGCACGCGCTGCGCCGCCCGGCCGGGACAGTGCGCCCCGGCGGCTTGCTGCGGCGCCT
GCTCGGCAGCATGCCGCGCCAAAGCGCACTGGTCGCCGAGGCCGGCGCCCTTCCGTTCGCCCGCGCCAGCGTCGATCTGG
TGTGGTCCAACCTGCTGCTGCCCGCGCTCGACGATCCGCTCCCGGTCCTGCAGGAAGCCCACCGCGTACTGGAAGTCGGC
GGCATGCTGATGTTCTCCACGCTCGGGCCCGACAGCCTGAAGGAACTGCGCGCCTGCCTGCCCACGGCGGCCGGCGAGCG
CGTGCATCGTTTCATCGACATGCATGACATCGGCGATGCGCTGGTGAAGGCCGGGTTTTCCGACCCGGTCATGGATATGG
AGATGCTGACCATGACCTACACCCGGCTCGACGACCTGTTCACCGACCTGCGCACCGCCGCTGGGGGCAACGCAAGCACG
GCCCGTCCCCGCGGTCTGACCGGGCGGCAGGGCTGGGACGAAGCGCGCGCGGCCTACGAAAGCCTGCGCCGCGACGGCCG
CCTACCCGCCACCTTCGAGGTCATCCAGGGCCACGCGTGGAAAGCGGCACCGAAGACGACCGAGGACGGGCGCAGCATCG
TGCGCTTCCAGCCCCGCCCGCCGCGCACCGGAAGCTGA

Upstream 100 bases:

>100_bases
CCAACTCGATCTTCTACGGCGAACGCCTGCTGACCACCGACAATCCGGAATCCGACCGCGACGACGTGCTGTTCGCACGC
CTCGGCCTGCGTTCGGTGTG

Downstream 100 bases:

>100_bases
GCGGACAATGACGCTTCGCACCGGCGCCCCGACCTGGCTGTTCGACCTCGACAACACGCTGCACAACGCCAGCCCGCACA
TCTTTCCGCACATCAACCGC

Product: putative biotin synthesis protein

Products: NA

Alternate protein names: Biotin Synthesis Protein BioC; Methyltransferase Type; Biotin Synthesis Protein; SAM-Dependent Methyltransferase; Methyltransferase; Biotin Synthesis Protein Bioc; Biotin Synthase BioC; UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase; Biotin Biosynthesis-Like Protein; LOW QUALITY PROTEIN Biotin Synthesis Protein; S-Adenosyl-L-Methionine-Dependent Methyltransferases; Methyltransferase Domain-Containing Protein; BIOTIN SYNSIS METHYLTRANSFERASE BioC; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Biotin Biosynthesis Methyltransferase BioC; Methyltransferase Domain Family; UbiE/COQ5 Methyltransferase

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAAADTDFHLDRALLRRRFAAAAGRYDEADVLAREIARRMDERLDYIRHSPRRILDLGCGTGADLPRLAERYPEAHLVAA
DFAAPMASHALRRPAGTVRPGGLLRRLLGSMPRQSALVAEAGALPFARASVDLVWSNLLLPALDDPLPVLQEAHRVLEVG
GMLMFSTLGPDSLKELRACLPTAAGERVHRFIDMHDIGDALVKAGFSDPVMDMEMLTMTYTRLDDLFTDLRTAAGGNAST
ARPRGLTGRQGWDEARAAYESLRRDGRLPATFEVIQGHAWKAAPKTTEDGRSIVRFQPRPPRTGS

Sequences:

>Translated_305_residues
MAAADTDFHLDRALLRRRFAAAAGRYDEADVLAREIARRMDERLDYIRHSPRRILDLGCGTGADLPRLAERYPEAHLVAA
DFAAPMASHALRRPAGTVRPGGLLRRLLGSMPRQSALVAEAGALPFARASVDLVWSNLLLPALDDPLPVLQEAHRVLEVG
GMLMFSTLGPDSLKELRACLPTAAGERVHRFIDMHDIGDALVKAGFSDPVMDMEMLTMTYTRLDDLFTDLRTAAGGNAST
ARPRGLTGRQGWDEARAAYESLRRDGRLPATFEVIQGHAWKAAPKTTEDGRSIVRFQPRPPRTGS
>Mature_304_residues
AAADTDFHLDRALLRRRFAAAAGRYDEADVLAREIARRMDERLDYIRHSPRRILDLGCGTGADLPRLAERYPEAHLVAAD
FAAPMASHALRRPAGTVRPGGLLRRLLGSMPRQSALVAEAGALPFARASVDLVWSNLLLPALDDPLPVLQEAHRVLEVGG
MLMFSTLGPDSLKELRACLPTAAGERVHRFIDMHDIGDALVKAGFSDPVMDMEMLTMTYTRLDDLFTDLRTAAGGNASTA
RPRGLTGRQGWDEARAAYESLRRDGRLPATFEVIQGHAWKAAPKTTEDGRSIVRFQPRPPRTGS

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=301, Percent_Identity=27.5747508305648, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17535003, Length=287, Percent_Identity=25.7839721254355, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922210, Length=303, Percent_Identity=29.3729372937294, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33482; Mature: 33351

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAADTDFHLDRALLRRRFAAAAGRYDEADVLAREIARRMDERLDYIRHSPRRILDLGCG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
TGADLPRLAERYPEAHLVAADFAAPMASHALRRPAGTVRPGGLLRRLLGSMPRQSALVAE
CCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHH
AGALPFARASVDLVWSNLLLPALDDPLPVLQEAHRVLEVGGMLMFSTLGPDSLKELRACL
HCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHH
PTAAGERVHRFIDMHDIGDALVKAGFSDPVMDMEMLTMTYTRLDDLFTDLRTAAGGNAST
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ARPRGLTGRQGWDEARAAYESLRRDGRLPATFEVIQGHAWKAAPKTTEDGRSIVRFQPRP
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCC
PRTGS
CCCCC
>Mature Secondary Structure 
AAADTDFHLDRALLRRRFAAAAGRYDEADVLAREIARRMDERLDYIRHSPRRILDLGCG
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
TGADLPRLAERYPEAHLVAADFAAPMASHALRRPAGTVRPGGLLRRLLGSMPRQSALVAE
CCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHH
AGALPFARASVDLVWSNLLLPALDDPLPVLQEAHRVLEVGGMLMFSTLGPDSLKELRACL
HCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHH
PTAAGERVHRFIDMHDIGDALVKAGFSDPVMDMEMLTMTYTRLDDLFTDLRTAAGGNAST
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ARPRGLTGRQGWDEARAAYESLRRDGRLPATFEVIQGHAWKAAPKTTEDGRSIVRFQPRP
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCC
PRTGS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA