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The map label for this gene is dinP [H]

Identifier: 119899076

GI number: 119899076

Start: 3067852

End: 3068925

Strand: Reverse

Name: dinP [H]

Synonym: azo2786

Alternate gene names: 119899076

Gene position: 3068925-3067852 (Counterclockwise)

Preceding gene: 119899077

Following gene: 119899075

Centisome position: 70.13

GC content: 70.3

Gene sequence:

>1074_bases
ATGCGCAAGATCATCCACTGCGACTGCGATTGCTTCTACGCTGCGGTCGAGGTCCGCGACAACCCCGCGCTCGCCGGCAA
GCCGGTGGCGGTCGGCGGGCGGGCGGAAACCCGCGGCGTGATCGCCACCTGCAGCTACGAGGCGCGCGCCTTCGGCGTCC
ATTCGGCGATGTCCACCGCGCGTGCGCTGCAGCGCTGCCCGCAGTTGATCCTGCTGCCGCCCGACTTCGAACGCTACCGG
GCCGCCTCGCGCCAGATTCTCGCGATCTACCGCGACTACACCGCGCTGGTGGAGCCGCTGTCGCTCGACGAGGCCTATCT
GGACGTCAGCGGGGTGGATCGCTGCAAGGGCTCGGCGACCTTGATGGCGCAGGAGATCCGCGCCCGCATCCGCGCCGAGG
TGGGCATCACCGCGTCGGCCGGCATCGCACCCAACAAGTTTCTGGCCAAGGTGGCGAGCGACTGGAACAAGCCGGACGGG
CAGTTCGTGGTGCGGCCGGACGAGGTGGCTGCCTTTGTCGCCGCGCTGCCGGTGAAGAAGATTTTCGGCGTCGGCAAGGT
CACCGCGGCCAGGCTCAACCGCCTCGGCGTGCACACCTGCGGCGATCTGCGGCCCTGGACGCTGGCCGCGCTGACGCGCG
AGTTCGGCAGCTTCGGCGCCAGCCTGCACCGGCTGTGCCGCGGCATCGACGAGCGTGAGGTCAAGCCCGACCGGGTCCGC
AAGTCCTTGTCCGTCGAAACCACCTACGTCACCGACCTGCCCGATCTCGCCGCCTGCGCGGCGGCGCTGCCGGCATTGAT
CGAGGAGTTCGGCCGCCGTTTCGGCAGGGCGCGCGACCTGCGGCCGGTGCACAAGGCGGTGGTGAAGATCAAGTTTGCGG
ATTTCTCGCAGACCACGGTGGAGTGCGTCGCGAGCGCGCCGGACACCGCGGTCTGGCAGGCGCTGCTGGCCGAAGGCCAT
GCCCGTCGCGGGCTGCCGGTGCGTCTGCTCGGCGTGGGGGTACGCTTCGCCGAAGAAGGCCGCGACGCAGCGGTGGCGCG
CCAGATCGGCCTGTTCGGCGAAACCGCGGGCTGA

Upstream 100 bases:

>100_bases
GCCGGTGCGCCCGGCGCTGCGCGTGGCGGGCGACGAGGCGGGCTGACGCGGTCGGTCCCCGAGCGGCTGGCGGCACGTCC
CGGTTCGTCCTGCACACAGC

Downstream 100 bases:

>100_bases
GCGCTGCGCAGCGGAGGGCGGGCTCCGGGCGATAATCGGCTGTTTGCCACCCGCCGCCGAGATGTCCATGAGTGATCCGC
AGTCCATTGCGCTGGAAACC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRKIIHCDCDCFYAAVEVRDNPALAGKPVAVGGRAETRGVIATCSYEARAFGVHSAMSTARALQRCPQLILLPPDFERYR
AASRQILAIYRDYTALVEPLSLDEAYLDVSGVDRCKGSATLMAQEIRARIRAEVGITASAGIAPNKFLAKVASDWNKPDG
QFVVRPDEVAAFVAALPVKKIFGVGKVTAARLNRLGVHTCGDLRPWTLAALTREFGSFGASLHRLCRGIDEREVKPDRVR
KSLSVETTYVTDLPDLAACAAALPALIEEFGRRFGRARDLRPVHKAVVKIKFADFSQTTVECVASAPDTAVWQALLAEGH
ARRGLPVRLLGVGVRFAEEGRDAAVARQIGLFGETAG

Sequences:

>Translated_357_residues
MRKIIHCDCDCFYAAVEVRDNPALAGKPVAVGGRAETRGVIATCSYEARAFGVHSAMSTARALQRCPQLILLPPDFERYR
AASRQILAIYRDYTALVEPLSLDEAYLDVSGVDRCKGSATLMAQEIRARIRAEVGITASAGIAPNKFLAKVASDWNKPDG
QFVVRPDEVAAFVAALPVKKIFGVGKVTAARLNRLGVHTCGDLRPWTLAALTREFGSFGASLHRLCRGIDEREVKPDRVR
KSLSVETTYVTDLPDLAACAAALPALIEEFGRRFGRARDLRPVHKAVVKIKFADFSQTTVECVASAPDTAVWQALLAEGH
ARRGLPVRLLGVGVRFAEEGRDAAVARQIGLFGETAG
>Mature_357_residues
MRKIIHCDCDCFYAAVEVRDNPALAGKPVAVGGRAETRGVIATCSYEARAFGVHSAMSTARALQRCPQLILLPPDFERYR
AASRQILAIYRDYTALVEPLSLDEAYLDVSGVDRCKGSATLMAQEIRARIRAEVGITASAGIAPNKFLAKVASDWNKPDG
QFVVRPDEVAAFVAALPVKKIFGVGKVTAARLNRLGVHTCGDLRPWTLAALTREFGSFGASLHRLCRGIDEREVKPDRVR
KSLSVETTYVTDLPDLAACAAALPALIEEFGRRFGRARDLRPVHKAVVKIKFADFSQTTVECVASAPDTAVWQALLAEGH
ARRGLPVRLLGVGVRFAEEGRDAAVARQIGLFGETAG

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=33.3333333333333, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=33.2307692307692, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI154350220, Length=285, Percent_Identity=31.5789473684211, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI5729982, Length=345, Percent_Identity=28.695652173913, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=48.5981308411215, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1786425, Length=353, Percent_Identity=49.8583569405099, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1787432, Length=206, Percent_Identity=30.0970873786408, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=402, Percent_Identity=28.6069651741293, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17537959, Length=262, Percent_Identity=35.8778625954198, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI193205702, Length=338, Percent_Identity=26.3313609467456, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=163, Percent_Identity=36.8098159509202, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324921, Length=273, Percent_Identity=29.3040293040293, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19923006, Length=328, Percent_Identity=28.6585365853659, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=30.0353356890459, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=30.0353356890459, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24668444, Length=124, Percent_Identity=37.9032258064516, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 38673; Mature: 38673

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHCDCDCFYAAVEVRDNPALAGKPVAVGGRAETRGVIATCSYEARAFGVHSAMSTA
CCCEEEECCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHHH
RALQRCPQLILLPPDFERYRAASRQILAIYRDYTALVEPLSLDEAYLDVSGVDRCKGSAT
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCCHH
LMAQEIRARIRAEVGITASAGIAPNKFLAKVASDWNKPDGQFVVRPDEVAAFVAALPVKK
HHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHH
IFGVGKVTAARLNRLGVHTCGDLRPWTLAALTREFGSFGASLHRLCRGIDEREVKPDRVR
HHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSLSVETTYVTDLPDLAACAAALPALIEEFGRRFGRARDLRPVHKAVVKIKFADFSQTTV
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEECCCCHHHH
ECVASAPDTAVWQALLAEGHARRGLPVRLLGVGVRFAEEGRDAAVARQIGLFGETAG
HHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKIIHCDCDCFYAAVEVRDNPALAGKPVAVGGRAETRGVIATCSYEARAFGVHSAMSTA
CCCEEEECCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHHH
RALQRCPQLILLPPDFERYRAASRQILAIYRDYTALVEPLSLDEAYLDVSGVDRCKGSAT
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCCHH
LMAQEIRARIRAEVGITASAGIAPNKFLAKVASDWNKPDGQFVVRPDEVAAFVAALPVKK
HHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHH
IFGVGKVTAARLNRLGVHTCGDLRPWTLAALTREFGSFGASLHRLCRGIDEREVKPDRVR
HHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSLSVETTYVTDLPDLAACAAALPALIEEFGRRFGRARDLRPVHKAVVKIKFADFSQTTV
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEECCCCHHHH
ECVASAPDTAVWQALLAEGHARRGLPVRLLGVGVRFAEEGRDAAVARQIGLFGETAG
HHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]