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The map label for this gene is fliD [H]

Identifier: 119898996

GI number: 119898996

Start: 2988571

End: 2989992

Strand: Direct

Name: fliD [H]

Synonym: azo2706

Alternate gene names: 119898996

Gene position: 2988571-2989992 (Clockwise)

Preceding gene: 119898995

Following gene: 119898997

Centisome position: 68.29

GC content: 64.21

Gene sequence:

>1422_bases
ATGGCAGCGATCACCAGCAGCGGCTCGATTCTCGACATCGACTCGCTGGTCAAGGGCCTGATGTCGGTCGAAAGCCGGCC
GCTCAGCCTGCTCGCCACCAAGGAAGCCAGCTACCAGGCGAAGCTTTCTGCCTTCGGGCAGATCAAGAGCGCCCTGACCT
CCCTGCAGACGGCAACAACCGCACTCAACAGCACGGACAAATTTGCCGCCACCAAGGCAACAGTTGCCGGCGACGGCTTC
ACCGCCACTTCGGACGCGAAGGCCGCCGCAGGCAGCTACAGCATCGACGTGACGCAGATGGCCAAGATCCAGCGCGTGTC
CACCGCCACGTCCAGCACCTTCGTGCCCGCGGCGGGCAAGATGACCATCGAGTACGGCACGGTCAAGACCACCGACGGCA
CCAAGAGCTTCGCCAGCGACTCTCCACCGCGCACCGCCACCCTCGATTTCGAAGGCGGCACGCTGGAACAACTGCGCGAT
GCGATCAACAAGGACACCACGCTCGGCCTCAAGGCCAGCATCGTGAACAACGGCACCACCAGCCAGCTGGTGCTCAGCGG
CACCAAGACCGGCGCCAACATGGCGTTCAAGCTCACCGGGGAATCGGGTCTGGCCGACCTCAGCTTCGACCCCTCCGCCA
CCGCCGCGGCCGGCGACAAGATGTACTCGGTGCAAGCCGCGCAGGACGCGCTGCTGAAGGTCGACGGCATCAGCGTTACC
CGGAGCAGCAACACCATTTCGGACGTCATCGACGGCGTGACGCTGACGCTGAACAAGGAGCCGAGTGGCACCGCGACCTC
GCTTTCGGGCACGGTCACGGTCGCCGCCGACCAGAGCGCGGCCAAGACCGCGGTCGATGCCTTCGTGAAGGCGTACAACG
AGGTGCAGAGCACGCTCAAGTCGCTGACCGCCTACAACACCGAAACCGACACCGCGGCGACACTCACCGGCGACGCGACC
GCCCGCAGCATCCAGGGCCAGTTGCGCAGCGCGCTGGCGCAGAGTTTTAGCGGGCTGGGCAATGCCAGCTCGCTGTCGCA
GATCGGCATCACCTTCGCCAAAGACGGCACGCTCAGCGTCGACAGCACCAAGTTCAACAAGGCGATGAGCGATCCGGCGA
TGAACGTCGGCGCGCTGTTCGCCGGCACCGACAAGATCGACGGCTTCGCCGACGTGTTCTCGAAGAAGCTGTCCAGCATG
ATCGACAGCGGCGGCGTCATCGCCAGCCGTACCGACGGCATCAACTCGACGATCAAGTCGATCACCAAGCAGTATGACGC
GATGGAAACCCGGCTCGAGGCGATGGAAGCGCGCTACCGCAGCCAGTTCTCGTCGCTGGACACGCTGCTGTCCGGCATGA
GCCAGACCAGCACCTATCTGTCTCAGCAGTTGGCCAATCTGCCGTCCACTTCGCGGAAATAA

Upstream 100 bases:

>100_bases
CGTCCGAGGAGATCATCTCGATCGCGAAGGCGATCGACAAACTGCAAGGCCTGCTGGTCCAACAGAAGGCCTGACCGTTC
AGCGCAAGGAGGACCCCACC

Downstream 100 bases:

>100_bases
GGAGCACCGGCATGTTCGGATCCACTTCCTATGCCAATCGCGCCGCCGCGTATGCGCGCGTGGGCACCGAAACCAGCGTG
GAGGCCGCCTCCCCGCACAA

Product: flagellar hook-associated protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MAAITSSGSILDIDSLVKGLMSVESRPLSLLATKEASYQAKLSAFGQIKSALTSLQTATTALNSTDKFAATKATVAGDGF
TATSDAKAAAGSYSIDVTQMAKIQRVSTATSSTFVPAAGKMTIEYGTVKTTDGTKSFASDSPPRTATLDFEGGTLEQLRD
AINKDTTLGLKASIVNNGTTSQLVLSGTKTGANMAFKLTGESGLADLSFDPSATAAAGDKMYSVQAAQDALLKVDGISVT
RSSNTISDVIDGVTLTLNKEPSGTATSLSGTVTVAADQSAAKTAVDAFVKAYNEVQSTLKSLTAYNTETDTAATLTGDAT
ARSIQGQLRSALAQSFSGLGNASSLSQIGITFAKDGTLSVDSTKFNKAMSDPAMNVGALFAGTDKIDGFADVFSKKLSSM
IDSGGVIASRTDGINSTIKSITKQYDAMETRLEAMEARYRSQFSSLDTLLSGMSQTSTYLSQQLANLPSTSRK

Sequences:

>Translated_473_residues
MAAITSSGSILDIDSLVKGLMSVESRPLSLLATKEASYQAKLSAFGQIKSALTSLQTATTALNSTDKFAATKATVAGDGF
TATSDAKAAAGSYSIDVTQMAKIQRVSTATSSTFVPAAGKMTIEYGTVKTTDGTKSFASDSPPRTATLDFEGGTLEQLRD
AINKDTTLGLKASIVNNGTTSQLVLSGTKTGANMAFKLTGESGLADLSFDPSATAAAGDKMYSVQAAQDALLKVDGISVT
RSSNTISDVIDGVTLTLNKEPSGTATSLSGTVTVAADQSAAKTAVDAFVKAYNEVQSTLKSLTAYNTETDTAATLTGDAT
ARSIQGQLRSALAQSFSGLGNASSLSQIGITFAKDGTLSVDSTKFNKAMSDPAMNVGALFAGTDKIDGFADVFSKKLSSM
IDSGGVIASRTDGINSTIKSITKQYDAMETRLEAMEARYRSQFSSLDTLLSGMSQTSTYLSQQLANLPSTSRK
>Mature_472_residues
AAITSSGSILDIDSLVKGLMSVESRPLSLLATKEASYQAKLSAFGQIKSALTSLQTATTALNSTDKFAATKATVAGDGFT
ATSDAKAAAGSYSIDVTQMAKIQRVSTATSSTFVPAAGKMTIEYGTVKTTDGTKSFASDSPPRTATLDFEGGTLEQLRDA
INKDTTLGLKASIVNNGTTSQLVLSGTKTGANMAFKLTGESGLADLSFDPSATAAAGDKMYSVQAAQDALLKVDGISVTR
SSNTISDVIDGVTLTLNKEPSGTATSLSGTVTVAADQSAAKTAVDAFVKAYNEVQSTLKSLTAYNTETDTAATLTGDATA
RSIQGQLRSALAQSFSGLGNASSLSQIGITFAKDGTLSVDSTKFNKAMSDPAMNVGALFAGTDKIDGFADVFSKKLSSMI
DSGGVIASRTDGINSTIKSITKQYDAMETRLEAMEARYRSQFSSLDTLLSGMSQTSTYLSQQLANLPSTSRK

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=485, Percent_Identity=35.6701030927835, Blast_Score=221, Evalue=6e-59,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 48828; Mature: 48697

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAITSSGSILDIDSLVKGLMSVESRPLSLLATKEASYQAKLSAFGQIKSALTSLQTATT
CCEECCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALNSTDKFAATKATVAGDGFTATSDAKAAAGSYSIDVTQMAKIQRVSTATSSTFVPAAGK
HHCCCCHHHHCEEEECCCCCCCCCCCHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCE
MTIEYGTVKTTDGTKSFASDSPPRTATLDFEGGTLEQLRDAINKDTTLGLKASIVNNGTT
EEEEECEEEECCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCC
SQLVLSGTKTGANMAFKLTGESGLADLSFDPSATAAAGDKMYSVQAAQDALLKVDGISVT
CEEEEECCCCCCCEEEEEECCCCCEECCCCCCCCHHCCCCEEEHHHHHHHHEEECCEEEE
RSSNTISDVIDGVTLTLNKEPSGTATSLSGTVTVAADQSAAKTAVDAFVKAYNEVQSTLK
ECCCCHHHHHCCEEEEECCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
SLTAYNTETDTAATLTGDATARSIQGQLRSALAQSFSGLGNASSLSQIGITFAKDGTLSV
HHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEECCCCEEE
DSTKFNKAMSDPAMNVGALFAGTDKIDGFADVFSKKLSSMIDSGGVIASRTDGINSTIKS
CCHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
ITKQYDAMETRLEAMEARYRSQFSSLDTLLSGMSQTSTYLSQQLANLPSTSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AAITSSGSILDIDSLVKGLMSVESRPLSLLATKEASYQAKLSAFGQIKSALTSLQTATT
CEECCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALNSTDKFAATKATVAGDGFTATSDAKAAAGSYSIDVTQMAKIQRVSTATSSTFVPAAGK
HHCCCCHHHHCEEEECCCCCCCCCCCHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCE
MTIEYGTVKTTDGTKSFASDSPPRTATLDFEGGTLEQLRDAINKDTTLGLKASIVNNGTT
EEEEECEEEECCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCC
SQLVLSGTKTGANMAFKLTGESGLADLSFDPSATAAAGDKMYSVQAAQDALLKVDGISVT
CEEEEECCCCCCCEEEEEECCCCCEECCCCCCCCHHCCCCEEEHHHHHHHHEEECCEEEE
RSSNTISDVIDGVTLTLNKEPSGTATSLSGTVTVAADQSAAKTAVDAFVKAYNEVQSTLK
ECCCCHHHHHCCEEEEECCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
SLTAYNTETDTAATLTGDATARSIQGQLRSALAQSFSGLGNASSLSQIGITFAKDGTLSV
HHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEECCCCEEE
DSTKFNKAMSDPAMNVGALFAGTDKIDGFADVFSKKLSSMIDSGGVIASRTDGINSTIKS
CCHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
ITKQYDAMETRLEAMEARYRSQFSSLDTLLSGMSQTSTYLSQQLANLPSTSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527488; 9097040; 9278503; 2659972; 6305924 [H]