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The map label for this gene is dhaR [H]

Identifier: 119898796

GI number: 119898796

Start: 2771064

End: 2771702

Strand: Direct

Name: dhaR [H]

Synonym: azo2505

Alternate gene names: 119898796

Gene position: 2771064-2771702 (Clockwise)

Preceding gene: 119898795

Following gene: 119898797

Centisome position: 63.32

GC content: 64.32

Gene sequence:

>639_bases
ATGGATGCGCCGCCCCTTACCCCCCGTCGCCGCGGCAGGCCCCCGAAGCAGCGGGAAGACCTGATCGGAACACGTGAATT
GCTGTTGCGTGCGGGCCTGGAAGTGCTCACCGAAAAGGGGTTCTCCGCCACCGGCATCGAGGAAATCCTGGGTCGGGTAA
ACGTGCCCAAGGGCTCGTTCTACCATTACTTCGACAGCAAGGAATCCTTCGGCCTGGAACTCATCCAGCGCTATGGCGAG
TTTTTCGCGAGGAAGCTGGACCGCCACCTGCTGAACGACGCGCTTTCGCCGCTCGATCGCCTGCGCGCCTTCGTCGCCGA
TGCGAAAGACGGCATGGCGCGGCACGCCTACCGCCGCGGCTGCCTGATCGGAAACCTCGGGCAGGAGATGGGCGCGCTGC
CCGAAAGCTTCCGCGCCAGCCTGAAAGAGACCTTCGAAGACTGGCAGACCCGTTTTTCCACCTGTCTGATGGCAGCCCAG
CAGGCCGGAGAACTGTCCCCCTGCGCGAATCCGCCACAACTCGCCGCCTTCTTCTGGATCGGCTGGGAGGGTGCGGTGCT
GCGCGCCAAGCTCGAGCAATCCGCCGCGCCGCTCGACGTTTTTGCCGATTTCTTCTTTGCGGGTTTGCCGCCCGCCTGA

Upstream 100 bases:

>100_bases
GGCCACGGGGGTGCCTCCGTTTCCGCCGCTCCGTTGCCGGCGCAATGCGCCGTACTCGGGAAGGATTGTTTTTACGAGAC
AGTCAGTCCAATATCTCGTC

Downstream 100 bases:

>100_bases
CTTTTTTTAAGCTCGACTAGACGCTCGGTCTAAATACCTACGACGCGCAAGCGCCCATTCAAGTCCATTTATTCTTGTCA
CGCAGAGGAGTGAAACATGG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MDAPPLTPRRRGRPPKQREDLIGTRELLLRAGLEVLTEKGFSATGIEEILGRVNVPKGSFYHYFDSKESFGLELIQRYGE
FFARKLDRHLLNDALSPLDRLRAFVADAKDGMARHAYRRGCLIGNLGQEMGALPESFRASLKETFEDWQTRFSTCLMAAQ
QAGELSPCANPPQLAAFFWIGWEGAVLRAKLEQSAAPLDVFADFFFAGLPPA

Sequences:

>Translated_212_residues
MDAPPLTPRRRGRPPKQREDLIGTRELLLRAGLEVLTEKGFSATGIEEILGRVNVPKGSFYHYFDSKESFGLELIQRYGE
FFARKLDRHLLNDALSPLDRLRAFVADAKDGMARHAYRRGCLIGNLGQEMGALPESFRASLKETFEDWQTRFSTCLMAAQ
QAGELSPCANPPQLAAFFWIGWEGAVLRAKLEQSAAPLDVFADFFFAGLPPA
>Mature_212_residues
MDAPPLTPRRRGRPPKQREDLIGTRELLLRAGLEVLTEKGFSATGIEEILGRVNVPKGSFYHYFDSKESFGLELIQRYGE
FFARKLDRHLLNDALSPLDRLRAFVADAKDGMARHAYRRGCLIGNLGQEMGALPESFRASLKETFEDWQTRFSTCLMAAQ
QAGELSPCANPPQLAAFFWIGWEGAVLRAKLEQSAAPLDVFADFFFAGLPPA

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=176, Percent_Identity=32.3863636363636, Blast_Score=100, Evalue=7e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23707; Mature: 23707

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAPPLTPRRRGRPPKQREDLIGTRELLLRAGLEVLTEKGFSATGIEEILGRVNVPKGSF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCE
YHYFDSKESFGLELIQRYGEFFARKLDRHLLNDALSPLDRLRAFVADAKDGMARHAYRRG
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
CLIGNLGQEMGALPESFRASLKETFEDWQTRFSTCLMAAQQAGELSPCANPPQLAAFFWI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEE
GWEGAVLRAKLEQSAAPLDVFADFFFAGLPPA
CCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDAPPLTPRRRGRPPKQREDLIGTRELLLRAGLEVLTEKGFSATGIEEILGRVNVPKGSF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCE
YHYFDSKESFGLELIQRYGEFFARKLDRHLLNDALSPLDRLRAFVADAKDGMARHAYRRG
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
CLIGNLGQEMGALPESFRASLKETFEDWQTRFSTCLMAAQQAGELSPCANPPQLAAFFWI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEE
GWEGAVLRAKLEQSAAPLDVFADFFFAGLPPA
CCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]