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The map label for this gene is fadD2 [H]

Identifier: 119898790

GI number: 119898790

Start: 2762390

End: 2764258

Strand: Reverse

Name: fadD2 [H]

Synonym: azo2499

Alternate gene names: 119898790

Gene position: 2764258-2762390 (Counterclockwise)

Preceding gene: 119898791

Following gene: 119898789

Centisome position: 63.17

GC content: 66.08

Gene sequence:

>1869_bases
ATGGAAACGGTGATTCGTGACGTTGGCCGGATGTTTGCCAAGCCGGTCGTCAATGTCGAAACGCGCGGCGATGGTTCGCG
CATCCTGCGGTCCGGGATTCCGCTTCCCGACACCTATGCCCGCTGCGTCGGCGAGTGGGTGGAGAAGTGGGGCAAGGAAA
CGCCCGACCAGCTCTTCCTCGCCGAACGCGATGCGGTCAGCGGCGAGTGGCGCAAGATCACCTGGGGCGAGACCCGCCGC
CGGGTGATCGGCATCGCCACCTGGCTGCTCGGCCAGAAGCTGTCGGCCGAGCGGCCGGTGGTGATCCTGTCGGACAACTC
GATCGAGCACGCGCTGCTGATGCTGGCGGCGATGCACGTCGGCGTGCCGGTCAGCTCGATCTCGCCGGGCAACTCGCTGA
TGTCCAGGGACCACGCCAAGCTCAAGGGCAACATCGAGCTGCTGCGTCCGGGGGTGATCTTTGCCGATCCGGTGGAGAAG
TTCGCCCCGGCGCTGGCGGCGATCCGCGAATTGCATGACGGCGTGGTGATCGCCGGCCGCAACAGCCAACCCACCGCGGG
CACCGTGCCCTTCGCCGAAATCGAAGTGGCGCCGGACGAGGCGGCGGTGATGGCGGCGTTCAACGCGATCACTCCCGACA
CCATCGCCAAGTTCCTGTTCACCTCCGGTTCGGTCGGCGTGCCCAAGGCGGTGATCAACACCCAGCGCATGATGTGCTCC
AACCAGCTCGCCAAGGAGCTGGTGTGGCCCTTCCTGAAGGAAAACCGGCCGGTGCTGGTGGAGTGGCTGCCGTGGAGCCA
CACCTTCGGCAGCAACCACAACCTCAACATGATCCTGCGCTGGGGCGGCACCATCTGGATCGACGACGGCAAGCCGACGC
CGGCAGGCCTCGACAAGACCGTGAAGAATCTCAAGGAGATTTCGCCCACGGTGTATTTCAACGTGCCGCGCGCCTACGAC
ATGCTGGTGCCGCTGCTGCGCGAGGACAAGCAGCTGCGCGAGACCTTCTTCGCACGGCTCAACCTGATCTTCTACGCCGG
GGCCGCGCTGCCGCACCACCTGTGGGAAGGCCTGGAGGATCTCTCCGAGCAGACCACCGGCCACAAGGTGACCATGGTGT
CGTCGTGGGGCTCGACCGAGACCGCGCCGATGTGCACCGACTGCCACTTCGAGGCCGAGCGCCCGGGCGTGATCGGTGTG
CCGGTGCCGGGCACGGCGCTCAAGCTGGTGCCCTCCGCCGACAAGCTGGAAGTGCGCGTGAAAGGCCCGAACATCTTCCC
CGGCTACTGGAAGCAGCCCGACATCACCGCCAAGTCCTTCGATGAAGAGGGCTATTACATGATCGGCGACGCCGTCGAAT
TCCTCGACGAGCGTTTCCCGGAAAAGGGGCTGCTGTTCGACGGCCGCGTCGGCGAGGACTTCAAGCTCCTCACCGGCACC
TGGGTGCATGTCGGCTCGCTGCGGGTGGCGGGCATCGACGCGATGAAGCCGGTGGCGCAGGACATCGTGGTGACCGGCCA
CGACCGCGACGAGATCGGCTTCCTGGTGTTCCCCAACATTCCGGAGTGCCGGACGCTGTGCCCGGACCTGCCGCCGGACG
CCGACATCATCGACCTGCTGCTGAACCCGGCGGTGCGCCAGCGCGTGCGCCAGGGCATGGCGCTGATGAAGCAGATCGGC
GGCGGCTCCTCCACCTATCCCTCGCGCGCGCTGCTGATGGCCGAACCGCCGTCGGTGGAGGCGGGCGAGATCACCGACAA
GGGCTACATCAACCAGCGCATGGTGCTCAACCGCCGTGCTGACCTGGTCGAGTACCTGTACCAGGACGTGGTGGACAAGA
CGGTGATCACCGTCCATTCCGCCATCTGA

Upstream 100 bases:

>100_bases
GGCCACGACAACCGCGCGCGCGTGCTGGTGAAGGTGGAAAACGGCGCCTACAAGCTGATGCGCGCCGAGTAAGACGACAG
GCAAGGGAACGGGGAATCCT

Downstream 100 bases:

>100_bases
GCCCCCCGAGGAAAACGAGAATGAGCGAACAACTGGTCAAGACTTCGTATGGCGACAGCGAGGCAGGGGACAACATCTAC
ACCATCACCCTGGCGCGCCC

Product: feruloyl-CoA synthase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
METVIRDVGRMFAKPVVNVETRGDGSRILRSGIPLPDTYARCVGEWVEKWGKETPDQLFLAERDAVSGEWRKITWGETRR
RVIGIATWLLGQKLSAERPVVILSDNSIEHALLMLAAMHVGVPVSSISPGNSLMSRDHAKLKGNIELLRPGVIFADPVEK
FAPALAAIRELHDGVVIAGRNSQPTAGTVPFAEIEVAPDEAAVMAAFNAITPDTIAKFLFTSGSVGVPKAVINTQRMMCS
NQLAKELVWPFLKENRPVLVEWLPWSHTFGSNHNLNMILRWGGTIWIDDGKPTPAGLDKTVKNLKEISPTVYFNVPRAYD
MLVPLLREDKQLRETFFARLNLIFYAGAALPHHLWEGLEDLSEQTTGHKVTMVSSWGSTETAPMCTDCHFEAERPGVIGV
PVPGTALKLVPSADKLEVRVKGPNIFPGYWKQPDITAKSFDEEGYYMIGDAVEFLDERFPEKGLLFDGRVGEDFKLLTGT
WVHVGSLRVAGIDAMKPVAQDIVVTGHDRDEIGFLVFPNIPECRTLCPDLPPDADIIDLLLNPAVRQRVRQGMALMKQIG
GGSSTYPSRALLMAEPPSVEAGEITDKGYINQRMVLNRRADLVEYLYQDVVDKTVITVHSAI

Sequences:

>Translated_622_residues
METVIRDVGRMFAKPVVNVETRGDGSRILRSGIPLPDTYARCVGEWVEKWGKETPDQLFLAERDAVSGEWRKITWGETRR
RVIGIATWLLGQKLSAERPVVILSDNSIEHALLMLAAMHVGVPVSSISPGNSLMSRDHAKLKGNIELLRPGVIFADPVEK
FAPALAAIRELHDGVVIAGRNSQPTAGTVPFAEIEVAPDEAAVMAAFNAITPDTIAKFLFTSGSVGVPKAVINTQRMMCS
NQLAKELVWPFLKENRPVLVEWLPWSHTFGSNHNLNMILRWGGTIWIDDGKPTPAGLDKTVKNLKEISPTVYFNVPRAYD
MLVPLLREDKQLRETFFARLNLIFYAGAALPHHLWEGLEDLSEQTTGHKVTMVSSWGSTETAPMCTDCHFEAERPGVIGV
PVPGTALKLVPSADKLEVRVKGPNIFPGYWKQPDITAKSFDEEGYYMIGDAVEFLDERFPEKGLLFDGRVGEDFKLLTGT
WVHVGSLRVAGIDAMKPVAQDIVVTGHDRDEIGFLVFPNIPECRTLCPDLPPDADIIDLLLNPAVRQRVRQGMALMKQIG
GGSSTYPSRALLMAEPPSVEAGEITDKGYINQRMVLNRRADLVEYLYQDVVDKTVITVHSAI
>Mature_622_residues
METVIRDVGRMFAKPVVNVETRGDGSRILRSGIPLPDTYARCVGEWVEKWGKETPDQLFLAERDAVSGEWRKITWGETRR
RVIGIATWLLGQKLSAERPVVILSDNSIEHALLMLAAMHVGVPVSSISPGNSLMSRDHAKLKGNIELLRPGVIFADPVEK
FAPALAAIRELHDGVVIAGRNSQPTAGTVPFAEIEVAPDEAAVMAAFNAITPDTIAKFLFTSGSVGVPKAVINTQRMMCS
NQLAKELVWPFLKENRPVLVEWLPWSHTFGSNHNLNMILRWGGTIWIDDGKPTPAGLDKTVKNLKEISPTVYFNVPRAYD
MLVPLLREDKQLRETFFARLNLIFYAGAALPHHLWEGLEDLSEQTTGHKVTMVSSWGSTETAPMCTDCHFEAERPGVIGV
PVPGTALKLVPSADKLEVRVKGPNIFPGYWKQPDITAKSFDEEGYYMIGDAVEFLDERFPEKGLLFDGRVGEDFKLLTGT
WVHVGSLRVAGIDAMKPVAQDIVVTGHDRDEIGFLVFPNIPECRTLCPDLPPDADIIDLLLNPAVRQRVRQGMALMKQIG
GGSSTYPSRALLMAEPPSVEAGEITDKGYINQRMVLNRRADLVEYLYQDVVDKTVITVHSAI

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=330, Percent_Identity=24.5454545454545, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI187761343, Length=330, Percent_Identity=24.5454545454545, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1788107, Length=260, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693145, Length=416, Percent_Identity=22.3557692307692, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17556552, Length=340, Percent_Identity=27.6470588235294, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558820, Length=513, Percent_Identity=22.4171539961014, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32563687, Length=408, Percent_Identity=23.2843137254902, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020459
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 68770; Mature: 68770

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVIRDVGRMFAKPVVNVETRGDGSRILRSGIPLPDTYARCVGEWVEKWGKETPDQLFL
CCHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
AERDAVSGEWRKITWGETRRRVIGIATWLLGQKLSAERPVVILSDNSIEHALLMLAAMHV
ECCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHH
GVPVSSISPGNSLMSRDHAKLKGNIELLRPGVIFADPVEKFAPALAAIRELHDGVVIAGR
CCCCCCCCCCHHHHHCCCHHHCCCEEEEECCCEEECCHHHHHHHHHHHHHHCCCEEEECC
NSQPTAGTVPFAEIEVAPDEAAVMAAFNAITPDTIAKFLFTSGSVGVPKAVINTQRMMCS
CCCCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
NQLAKELVWPFLKENRPVLVEWLPWSHTFGSNHNLNMILRWGGTIWIDDGKPTPAGLDKT
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCHHHH
VKNLKEISPTVYFNVPRAYDMLVPLLREDKQLRETFFARLNLIFYAGAALPHHLWEGLED
HHHHHHCCCEEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
LSEQTTGHKVTMVSSWGSTETAPMCTDCHFEAERPGVIGVPVPGTALKLVPSADKLEVRV
HHHHCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCEEEECCCCCEEEECCCCCEEEEEE
KGPNIFPGYWKQPDITAKSFDEEGYYMIGDAVEFLDERFPEKGLLFDGRVGEDFKLLTGT
ECCCCCCCCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEC
WVHVGSLRVAGIDAMKPVAQDIVVTGHDRDEIGFLVFPNIPECRTLCPDLPPDADIIDLL
EEEECCEEEECCHHHHHHHHCEEEECCCCCCCCEEECCCCCHHHHHCCCCCCCHHHHHHH
LNPAVRQRVRQGMALMKQIGGGSSTYPSRALLMAEPPSVEAGEITDKGYINQRMVLNRRA
HCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
DLVEYLYQDVVDKTVITVHSAI
HHHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure
METVIRDVGRMFAKPVVNVETRGDGSRILRSGIPLPDTYARCVGEWVEKWGKETPDQLFL
CCHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
AERDAVSGEWRKITWGETRRRVIGIATWLLGQKLSAERPVVILSDNSIEHALLMLAAMHV
ECCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHH
GVPVSSISPGNSLMSRDHAKLKGNIELLRPGVIFADPVEKFAPALAAIRELHDGVVIAGR
CCCCCCCCCCHHHHHCCCHHHCCCEEEEECCCEEECCHHHHHHHHHHHHHHCCCEEEECC
NSQPTAGTVPFAEIEVAPDEAAVMAAFNAITPDTIAKFLFTSGSVGVPKAVINTQRMMCS
CCCCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
NQLAKELVWPFLKENRPVLVEWLPWSHTFGSNHNLNMILRWGGTIWIDDGKPTPAGLDKT
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCHHHH
VKNLKEISPTVYFNVPRAYDMLVPLLREDKQLRETFFARLNLIFYAGAALPHHLWEGLED
HHHHHHCCCEEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
LSEQTTGHKVTMVSSWGSTETAPMCTDCHFEAERPGVIGVPVPGTALKLVPSADKLEVRV
HHHHCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCEEEECCCCCEEEECCCCCEEEEEE
KGPNIFPGYWKQPDITAKSFDEEGYYMIGDAVEFLDERFPEKGLLFDGRVGEDFKLLTGT
ECCCCCCCCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEC
WVHVGSLRVAGIDAMKPVAQDIVVTGHDRDEIGFLVFPNIPECRTLCPDLPPDADIIDLL
EEEECCEEEECCHHHHHHHHCEEEECCCCCCCCEEECCCCCHHHHHCCCCCCCHHHHHHH
LNPAVRQRVRQGMALMKQIGGGSSTYPSRALLMAEPPSVEAGEITDKGYINQRMVLNRRA
HCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
DLVEYLYQDVVDKTVITVHSAI
HHHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]