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The map label for this gene is lapB2 [H]

Identifier: 119898729

GI number: 119898729

Start: 2690810

End: 2691739

Strand: Reverse

Name: lapB2 [H]

Synonym: azo2438

Alternate gene names: 119898729

Gene position: 2691739-2690810 (Counterclockwise)

Preceding gene: 119898730

Following gene: 119898727

Centisome position: 61.51

GC content: 64.3

Gene sequence:

>930_bases
ATGGCAATGACCGACGTACTGCGCCCCGGCCACATTTCGCTGCGCGTGCTTGACCTGGAAGAGGGCGTCAATCACTACAA
GAACGTGCTCGGCCTGATCGAGACCGGCCGCGACAGCCAGGGCCGCGTGTATTTCAAGACCTGGGACGAGCGCGACCACA
ACAGCGTCGTGATCCGGGAGGCCGACAGTGCCGGCATGGATTTCTTCGGTTTCAAGGTGGCGAGCAAGGGCGCGCTGGAG
AAGCTGGACGGCCGCCTGAAGGAGTACGGCATCGTCACCGAACGCATTCCCGCGGGCGAGATGCTGGAAACCGGCGAGCG
CGTGCGTTTCCTGCTCCCGTCCGGCCACTACATCGAGCTCTACGCCGAGAAGACCGACGTCGGCAACGGCATGGCCTATG
TGAATCCGGACCCCTGGACCAAGGACGCAGAGCGCGGCATCGCCCCGATCCGCATGGACCACTGCCTGCTCTACGGCCCG
GACATCGAGAAGGTGCAGGACATCTTCGTGAACGTGCTCGGCTTCTACCTCGTGGAGCACGTGGTGATGGAAGACGGCAA
GACCGACCTCGGCATCTGGCTGTCGTGCTCGATCAAGGCCCACGACATCGCCTTCGTGCGCCACCCGGAGCCGGGCAAGC
TGCACCACGTCTCTTTCCTGCTCGACAGCTGGGAAAGGGTGCTGCGCGCCGCCGACCTGATGTCGATGAACAAGGTGTCG
ATCGACATCGGCCCCACCCGCCACGGCATCACCCGCGGCACCACCATCTACGCCTTCGATCCCTCGGGCAACCGCTTCGA
GACCTTCTGCGGCGGCTACCAGTGCTACCCGGACTGGCAGCCGATCAAGTGGACCTGGGACGAGGTCGGCGCGGGCATCT
TCTATCACGACCGCGCGCTGAACGAGCGCTTCCTGTCGGTGGTGTCCTGA

Upstream 100 bases:

>100_bases
GATTTATCGGTTTATAAAAGTATCATCCCGCTACTGGCCGTTTCGCCTTTCCACAGCGGCCGCTTGAAGGCCGCACAAAA
GACCACTGGAGGAGACCATC

Downstream 100 bases:

>100_bases
GCGTAGGTTGTGCGCGGTCTTGCTCCCTCCCCTTCAAGGGGGCGTAGGCGGCGTTTCGCAGAGCCTCGCTCTGCGCCGCC
GAAGCGGCGGAGCGAAGCGA

Product: catechol 2,3-dioxygenase

Products: NA

Alternate protein names: MPC; CatO2ase; Catechol 2,3-dioxygenase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAMTDVLRPGHISLRVLDLEEGVNHYKNVLGLIETGRDSQGRVYFKTWDERDHNSVVIREADSAGMDFFGFKVASKGALE
KLDGRLKEYGIVTERIPAGEMLETGERVRFLLPSGHYIELYAEKTDVGNGMAYVNPDPWTKDAERGIAPIRMDHCLLYGP
DIEKVQDIFVNVLGFYLVEHVVMEDGKTDLGIWLSCSIKAHDIAFVRHPEPGKLHHVSFLLDSWERVLRAADLMSMNKVS
IDIGPTRHGITRGTTIYAFDPSGNRFETFCGGYQCYPDWQPIKWTWDEVGAGIFYHDRALNERFLSVVS

Sequences:

>Translated_309_residues
MAMTDVLRPGHISLRVLDLEEGVNHYKNVLGLIETGRDSQGRVYFKTWDERDHNSVVIREADSAGMDFFGFKVASKGALE
KLDGRLKEYGIVTERIPAGEMLETGERVRFLLPSGHYIELYAEKTDVGNGMAYVNPDPWTKDAERGIAPIRMDHCLLYGP
DIEKVQDIFVNVLGFYLVEHVVMEDGKTDLGIWLSCSIKAHDIAFVRHPEPGKLHHVSFLLDSWERVLRAADLMSMNKVS
IDIGPTRHGITRGTTIYAFDPSGNRFETFCGGYQCYPDWQPIKWTWDEVGAGIFYHDRALNERFLSVVS
>Mature_308_residues
AMTDVLRPGHISLRVLDLEEGVNHYKNVLGLIETGRDSQGRVYFKTWDERDHNSVVIREADSAGMDFFGFKVASKGALEK
LDGRLKEYGIVTERIPAGEMLETGERVRFLLPSGHYIELYAEKTDVGNGMAYVNPDPWTKDAERGIAPIRMDHCLLYGPD
IEKVQDIFVNVLGFYLVEHVVMEDGKTDLGIWLSCSIKAHDIAFVRHPEPGKLHHVSFLLDSWERVLRAADLMSMNKVSI
DIGPTRHGITRGTTIYAFDPSGNRFETFCGGYQCYPDWQPIKWTWDEVGAGIFYHDRALNERFLSVVS

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017624
- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.2 [H]

Molecular weight: Translated: 35057; Mature: 34926

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00082 EXTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMTDVLRPGHISLRVLDLEEGVNHYKNVLGLIETGRDSQGRVYFKTWDERDHNSVVIRE
CCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEE
ADSAGMDFFGFKVASKGALEKLDGRLKEYGIVTERIPAGEMLETGERVRFLLPSGHYIEL
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCHHHHCCCEEEEEECCCCEEEE
YAEKTDVGNGMAYVNPDPWTKDAERGIAPIRMDHCLLYGPDIEKVQDIFVNVLGFYLVEH
EEECCCCCCCEEEECCCCCCCHHHCCCCCEEECEEEEECCCHHHHHHHHHHHHHHHHHHH
VVMEDGKTDLGIWLSCSIKAHDIAFVRHPEPGKLHHVSFLLDSWERVLRAADLMSMNKVS
HHHCCCCCCEEEEEEEEEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEE
IDIGPTRHGITRGTTIYAFDPSGNRFETFCGGYQCYPDWQPIKWTWDEVGAGIFYHDRAL
EEECCCCCCCCCCCEEEEECCCCCEEHHHCCCEEECCCCCCCEEEHHHHCCCEEEEHHHH
NERFLSVVS
HHHHHHHCC
>Mature Secondary Structure 
AMTDVLRPGHISLRVLDLEEGVNHYKNVLGLIETGRDSQGRVYFKTWDERDHNSVVIRE
CCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEE
ADSAGMDFFGFKVASKGALEKLDGRLKEYGIVTERIPAGEMLETGERVRFLLPSGHYIEL
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCHHHHCCCEEEEEECCCCEEEE
YAEKTDVGNGMAYVNPDPWTKDAERGIAPIRMDHCLLYGPDIEKVQDIFVNVLGFYLVEH
EEECCCCCCCEEEECCCCCCCHHHCCCCCEEECEEEEECCCHHHHHHHHHHHHHHHHHHH
VVMEDGKTDLGIWLSCSIKAHDIAFVRHPEPGKLHHVSFLLDSWERVLRAADLMSMNKVS
HHHCCCCCCEEEEEEEEEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEE
IDIGPTRHGITRGTTIYAFDPSGNRFETFCGGYQCYPDWQPIKWTWDEVGAGIFYHDRAL
EEECCCCCCCCCCCEEEEECCCCCEEHHHCCCEEECCCCCCCEEEHHHHCCCEEEEHHHH
NERFLSVVS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1672868 [H]