BacMap

Definition	Azoarcus sp. BH72 chromosome, complete genome.
Accession	NC_008702
Length	4,376,040

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The map label for this gene is nahI [H]

Identifier: 119898726

GI number: 119898726

Start: 2687635

End: 2689089

Strand: Reverse

Name: nahI [H]

Synonym: azo2435

Alternate gene names: 119898726

Gene position: 2689089-2687635 (Counterclockwise)

Preceding gene: 119898727

Following gene: 119898725

Centisome position: 61.45

GC content: 67.77

Gene sequence:

>1455_bases
ATGAAACAGATTCACAACTTCATCAACGGCGAGTTCGTCGCCACCGCGAAGCCCTTCGACAAGTGCTCGCCGCTCGACAA
CCGGCGCATCGCGCTGGTGCACGAAGCAGGCAAGACCGAGGTCGACGCCGCGGTCGCCGCCGCGCAGGCCGCGCTCAAGG
GACCGTGGGGCAGGATGACGGTGGCCGAGCGGGTGGACCTGCTCAACGCGGTGGCCGACGGCATCAACCGCCGCTTCGAC
GACTTCCTCGCCGCCGAATGCGCCGACACCGGCAAGCCGAAGAGCCTCGCCAGCCACATCGACATCCCGCGCGGCGCGGC
CAACTTCAAGGTGTTCGCCGACGTCATCAAGAGCGTGCCCACCGAGTTCTTCGAGATGGCCACGCCGGACGGCCGCGGTG
CGCTCAACTACGCGCTGCGCCGCCCGGTCGGCGTGGTCGGCGTGATCTGCCCGTGGAATTTGCCGCTGCTGCTGATGACC
TGGAAGGTCGGCCCGGCGCTAGCCTGCGGCAACACCGTGGTGGTCAAGCCCTCGGAAGAAACCCCGCAGACCGCGACCCT
GCTCGGCGAGGTGATGAACGAGGTCGGCATGCCCAAGGGCGTGTACAACGTGGTGCACGGCTTCGGGCCGGGCTCGGCGG
GGGAGTTCGTCACCACCCACCCCAAGGTCAATGCGATCACCTTCACCGGCGAAACCCGCACCGGCGCGGCGATCATGAAG
GCCGCCGCCGACGGCGCGCGCCCGGTGTCGCTGGAGATGGGCGGCAAGAACCCGGCCATCGTGTTCGCCGACTGCGATTT
CGATGCCGCCATCGAAGGCACCATGCGTTCGGTGTTCGCCAACTGCGGCCAGGTCTGCCTCGGCACCGAGCGGGTGTATG
TCGAGCGGCCGATCTTCGACCGCTTCGTCGCCGCGCTCAAGGCCGGTGCCGAGGGCCTCAAGCTGGGCGTGCCGGACGAT
GCCAGCACCGGCATGGGGCCGCTGATCTCGCAGGAGCACAAGAACAAGGTGCTCTCCTACTACAACAAGGCCAGGGAACT
CGGCGCCACCGTGGTTACCGGCGGCGGCGTGCCGCAGATGCCGGGCGAACTCGCCAACGGCGCCTGGGTGCAGCCCACCA
TCTGGACCGGGCTGGACGACAACTCGCCGATCGCGCGCGAGGAGATCTTCGGCCCCTGCACGCTGATCCAGCCCTTCGAT
GCGGAAGACGAAGTGATCCGCCGCGCCAACGACACCGACTACGGCCTCGCCTGCTCGGTGTGGACCAAGGACCTCGCCCG
CGCCCACCGCGTCGCCGGCCAGATCGAAGCCGGTCTGGTGTGGGTGAATTCCTGGTTCCTGCGCGACCTGCGCACCCCCT
TCGGTGGCGCCAAGCAGTCCGGCATCGGCCGCGAGGGCGGGGTGCATTCGCTCGAGTTCTATACCGAACAGAAGAACATC
TGCATCAAGCTCTGA

Upstream 100 bases:

>100_bases
CGCGCGCCGGGCTGAAGGCCATCGGCGCCGACGACATCCAGGATTGAGACAACCACGACGCCGGCCACGCAAAACGCCGA
GGCCGGTCACGGAGAGACCC

Downstream 100 bases:

>100_bases
GGGCGAGACAGGGGTTTCGCGGCGCACGCGCCGCGCCTGTCGAGCGGGCCGGCTGTGCAAAGCCGGCACTCCACGGGTTA
CCCCTCTTCGCGCAGCGACA

Product: 2-hydroxymuconic semialdehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: HMSD [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKQIHNFINGEFVATAKPFDKCSPLDNRRIALVHEAGKTEVDAAVAAAQAALKGPWGRMTVAERVDLLNAVADGINRRFD
DFLAAECADTGKPKSLASHIDIPRGAANFKVFADVIKSVPTEFFEMATPDGRGALNYALRRPVGVVGVICPWNLPLLLMT
WKVGPALACGNTVVVKPSEETPQTATLLGEVMNEVGMPKGVYNVVHGFGPGSAGEFVTTHPKVNAITFTGETRTGAAIMK
AAADGARPVSLEMGGKNPAIVFADCDFDAAIEGTMRSVFANCGQVCLGTERVYVERPIFDRFVAALKAGAEGLKLGVPDD
ASTGMGPLISQEHKNKVLSYYNKARELGATVVTGGGVPQMPGELANGAWVQPTIWTGLDDNSPIAREEIFGPCTLIQPFD
AEDEVIRRANDTDYGLACSVWTKDLARAHRVAGQIEAGLVWVNSWFLRDLRTPFGGAKQSGIGREGGVHSLEFYTEQKNI
CIKL

Sequences:

>Translated_484_residues
MKQIHNFINGEFVATAKPFDKCSPLDNRRIALVHEAGKTEVDAAVAAAQAALKGPWGRMTVAERVDLLNAVADGINRRFD
DFLAAECADTGKPKSLASHIDIPRGAANFKVFADVIKSVPTEFFEMATPDGRGALNYALRRPVGVVGVICPWNLPLLLMT
WKVGPALACGNTVVVKPSEETPQTATLLGEVMNEVGMPKGVYNVVHGFGPGSAGEFVTTHPKVNAITFTGETRTGAAIMK
AAADGARPVSLEMGGKNPAIVFADCDFDAAIEGTMRSVFANCGQVCLGTERVYVERPIFDRFVAALKAGAEGLKLGVPDD
ASTGMGPLISQEHKNKVLSYYNKARELGATVVTGGGVPQMPGELANGAWVQPTIWTGLDDNSPIAREEIFGPCTLIQPFD
AEDEVIRRANDTDYGLACSVWTKDLARAHRVAGQIEAGLVWVNSWFLRDLRTPFGGAKQSGIGREGGVHSLEFYTEQKNI
CIKL
>Mature_484_residues
MKQIHNFINGEFVATAKPFDKCSPLDNRRIALVHEAGKTEVDAAVAAAQAALKGPWGRMTVAERVDLLNAVADGINRRFD
DFLAAECADTGKPKSLASHIDIPRGAANFKVFADVIKSVPTEFFEMATPDGRGALNYALRRPVGVVGVICPWNLPLLLMT
WKVGPALACGNTVVVKPSEETPQTATLLGEVMNEVGMPKGVYNVVHGFGPGSAGEFVTTHPKVNAITFTGETRTGAAIMK
AAADGARPVSLEMGGKNPAIVFADCDFDAAIEGTMRSVFANCGQVCLGTERVYVERPIFDRFVAALKAGAEGLKLGVPDD
ASTGMGPLISQEHKNKVLSYYNKARELGATVVTGGGVPQMPGELANGAWVQPTIWTGLDDNSPIAREEIFGPCTLIQPFD
AEDEVIRRANDTDYGLACSVWTKDLARAHRVAGQIEAGLVWVNSWFLRDLRTPFGGAKQSGIGREGGVHSLEFYTEQKNI
CIKL

Specific function: 2-hydroxymuconic acid semialdehyde can be converted to 2-hydroxypent-2,4-dienoate either directly by the action of 2- hydroxymuconic semialdehyde hydrolase (HMSH) or by the action of three sequential enzymes, the first of which is HMSD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=485, Percent_Identity=42.8865979381443, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI153266822, Length=488, Percent_Identity=40.7786885245902, Blast_Score=348, Evalue=9e-96,
Organism=Homo sapiens, GI25952152, Length=485, Percent_Identity=40.2061855670103, Blast_Score=341, Evalue=1e-93,
Organism=Homo sapiens, GI115387104, Length=472, Percent_Identity=38.771186440678, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI25777732, Length=483, Percent_Identity=38.7163561076605, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI25777724, Length=489, Percent_Identity=37.0143149284254, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI25777730, Length=488, Percent_Identity=38.3196721311475, Blast_Score=318, Evalue=1e-86,
Organism=Homo sapiens, GI21361176, Length=491, Percent_Identity=38.2892057026477, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI238814322, Length=483, Percent_Identity=37.2670807453416, Blast_Score=301, Evalue=1e-81,
Organism=Homo sapiens, GI25777728, Length=427, Percent_Identity=37.7049180327869, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI21614513, Length=483, Percent_Identity=37.6811594202899, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI301500698, Length=482, Percent_Identity=35.8921161825726, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI25777726, Length=489, Percent_Identity=33.9468302658487, Blast_Score=271, Evalue=7e-73,
Organism=Homo sapiens, GI4507229, Length=484, Percent_Identity=36.3636363636364, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI25777721, Length=497, Percent_Identity=35.6136820925553, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI11095441, Length=480, Percent_Identity=28.5416666666667, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI188035924, Length=485, Percent_Identity=25.5670103092783, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI310128093, Length=477, Percent_Identity=25.7861635220126, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI310128103, Length=480, Percent_Identity=25.625, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4557303, Length=436, Percent_Identity=27.0642201834862, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI73466520, Length=436, Percent_Identity=27.0642201834862, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI206597441, Length=449, Percent_Identity=28.5077951002227, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI206597439, Length=449, Percent_Identity=28.5077951002227, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI22907049, Length=449, Percent_Identity=28.5077951002227, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI310128091, Length=340, Percent_Identity=30, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI71773324, Length=346, Percent_Identity=29.1907514450867, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI4502043, Length=349, Percent_Identity=28.9398280802292, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI238814371, Length=349, Percent_Identity=28.9398280802292, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI73695881, Length=348, Percent_Identity=28.448275862069, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI73695879, Length=348, Percent_Identity=28.448275862069, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI223972651, Length=345, Percent_Identity=28.695652173913, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI310128089, Length=330, Percent_Identity=28.7878787878788, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI310128097, Length=256, Percent_Identity=32.421875, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI238859541, Length=503, Percent_Identity=26.2425447316103, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI25777736, Length=503, Percent_Identity=26.2425447316103, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI25777734, Length=503, Percent_Identity=26.2425447316103, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310128095, Length=315, Percent_Identity=28.2539682539683, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI223972653, Length=345, Percent_Identity=26.0869565217391, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI310128087, Length=297, Percent_Identity=20.8754208754209, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786504, Length=487, Percent_Identity=40.6570841889117, Blast_Score=342, Evalue=3e-95,
Organism=Escherichia coli, GI1787558, Length=483, Percent_Identity=39.9585921325052, Blast_Score=340, Evalue=2e-94,
Organism=Escherichia coli, GI87082295, Length=485, Percent_Identity=36.701030927835, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI87081896, Length=464, Percent_Identity=37.7155172413793, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1787715, Length=432, Percent_Identity=37.962962962963, Blast_Score=291, Evalue=9e-80,
Organism=Escherichia coli, GI1789015, Length=480, Percent_Identity=36.0416666666667, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1787684, Length=480, Percent_Identity=31.4583333333333, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87081926, Length=447, Percent_Identity=27.0693512304251, Blast_Score=175, Evalue=7e-45,
Organism=Escherichia coli, GI1788042, Length=474, Percent_Identity=28.2700421940928, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787250, Length=371, Percent_Identity=28.3018867924528, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787653, Length=471, Percent_Identity=24.416135881104, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17551164, Length=482, Percent_Identity=42.3236514522822, Blast_Score=351, Evalue=5e-97,
Organism=Caenorhabditis elegans, GI25144435, Length=490, Percent_Identity=40.4081632653061, Blast_Score=341, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI17562198, Length=483, Percent_Identity=40.9937888198758, Blast_Score=340, Evalue=7e-94,
Organism=Caenorhabditis elegans, GI25143876, Length=480, Percent_Identity=37.5, Blast_Score=309, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI25143874, Length=480, Percent_Identity=37.5, Blast_Score=308, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI32564736, Length=434, Percent_Identity=40.3225806451613, Blast_Score=307, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI71995606, Length=483, Percent_Identity=38.3022774327122, Blast_Score=299, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI133930964, Length=484, Percent_Identity=36.9834710743802, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=38.0047505938242, Blast_Score=248, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI17534119, Length=477, Percent_Identity=33.9622641509434, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71986308, Length=463, Percent_Identity=30.4535637149028, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI115534176, Length=488, Percent_Identity=27.0491803278689, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI32566756, Length=344, Percent_Identity=28.7790697674419, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25146391, Length=344, Percent_Identity=28.7790697674419, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI25146394, Length=344, Percent_Identity=28.7790697674419, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17564084, Length=346, Percent_Identity=29.7687861271676, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534447, Length=466, Percent_Identity=26.6094420600858, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32564151, Length=421, Percent_Identity=26.603325415677, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115532534, Length=345, Percent_Identity=28.695652173913, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=300, Percent_Identity=26, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320917, Length=487, Percent_Identity=38.1930184804928, Blast_Score=332, Evalue=7e-92,
Organism=Saccharomyces cerevisiae, GI6324950, Length=481, Percent_Identity=37.6299376299376, Blast_Score=322, Evalue=9e-89,
Organism=Saccharomyces cerevisiae, GI6323821, Length=492, Percent_Identity=34.349593495935, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6323822, Length=492, Percent_Identity=34.5528455284553, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6325196, Length=491, Percent_Identity=31.9755600814664, Blast_Score=263, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6319478, Length=479, Percent_Identity=33.1941544885177, Blast_Score=245, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6321828, Length=469, Percent_Identity=27.7185501066098, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=491, Percent_Identity=24.847250509165, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=300, Percent_Identity=26.6666666666667, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129399, Length=491, Percent_Identity=39.7148676171079, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24650465, Length=484, Percent_Identity=39.2561983471074, Blast_Score=321, Evalue=8e-88,
Organism=Drosophila melanogaster, GI24585660, Length=483, Percent_Identity=36.0248447204969, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI281362580, Length=437, Percent_Identity=36.1556064073227, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI62472918, Length=437, Percent_Identity=36.1556064073227, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI62472926, Length=437, Percent_Identity=36.1556064073227, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI62472936, Length=437, Percent_Identity=36.1556064073227, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI21356737, Length=437, Percent_Identity=36.1556064073227, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI24638876, Length=480, Percent_Identity=27.5, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24638878, Length=480, Percent_Identity=27.5, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24666674, Length=487, Percent_Identity=25.4620123203285, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281360301, Length=343, Percent_Identity=28.8629737609329, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281360299, Length=343, Percent_Identity=28.8629737609329, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281360297, Length=343, Percent_Identity=28.8629737609329, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281360295, Length=343, Percent_Identity=28.8629737609329, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24586250, Length=343, Percent_Identity=28.8629737609329, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281360303, Length=343, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI45552499, Length=343, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24668425, Length=495, Percent_Identity=25.8585858585859, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24668417, Length=495, Percent_Identity=25.8585858585859, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24668413, Length=495, Percent_Identity=25.8585858585859, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574525, Length=466, Percent_Identity=24.8927038626609, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281360293, Length=157, Percent_Identity=34.3949044585987, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28571798, Length=520, Percent_Identity=24.6153846153846, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571796, Length=520, Percent_Identity=24.6153846153846, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571794, Length=520, Percent_Identity=24.6153846153846, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571802, Length=510, Percent_Identity=24.7058823529412, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571800, Length=510, Percent_Identity=24.7058823529412, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571806, Length=510, Percent_Identity=24.7058823529412, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017628 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 51815; Mature: 51815

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIHNFINGEFVATAKPFDKCSPLDNRRIALVHEAGKTEVDAAVAAAQAALKGPWGRMT
CCHHHHHHCCCEEEECCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCH
VAERVDLLNAVADGINRRFDDFLAAECADTGKPKSLASHIDIPRGAANFKVFADVIKSVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCC
TEFFEMATPDGRGALNYALRRPVGVVGVICPWNLPLLLMTWKVGPALACGNTVVVKPSEE
HHHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCEECCCEEEEECCCC
TPQTATLLGEVMNEVGMPKGVYNVVHGFGPGSAGEFVTTHPKVNAITFTGETRTGAAIMK
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHH
AAADGARPVSLEMGGKNPAIVFADCDFDAAIEGTMRSVFANCGQVCLGTERVYVERPIFD
HHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEECCCEEEEECCHHH
RFVAALKAGAEGLKLGVPDDASTGMGPLISQEHKNKVLSYYNKARELGATVVTGGGVPQM
HHHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
PGELANGAWVQPTIWTGLDDNSPIAREEIFGPCTLIQPFDAEDEVIRRANDTDYGLACSV
CHHHCCCCEECCEEEECCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHCCCCCCCCEEHH
WTKDLARAHRVAGQIEAGLVWVNSWFLRDLRTPFGGAKQSGIGREGGVHSLEFYTEQKNI
HHHHHHHHHHHHCCHHCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCE
CIKL
EEEC
>Mature Secondary Structure
MKQIHNFINGEFVATAKPFDKCSPLDNRRIALVHEAGKTEVDAAVAAAQAALKGPWGRMT
CCHHHHHHCCCEEEECCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCH
VAERVDLLNAVADGINRRFDDFLAAECADTGKPKSLASHIDIPRGAANFKVFADVIKSVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCC
TEFFEMATPDGRGALNYALRRPVGVVGVICPWNLPLLLMTWKVGPALACGNTVVVKPSEE
HHHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCEECCCEEEEECCCC
TPQTATLLGEVMNEVGMPKGVYNVVHGFGPGSAGEFVTTHPKVNAITFTGETRTGAAIMK
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHH
AAADGARPVSLEMGGKNPAIVFADCDFDAAIEGTMRSVFANCGQVCLGTERVYVERPIFD
HHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEECCCEEEEECCHHH
RFVAALKAGAEGLKLGVPDDASTGMGPLISQEHKNKVLSYYNKARELGATVVTGGGVPQM
HHHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
PGELANGAWVQPTIWTGLDDNSPIAREEIFGPCTLIQPFDAEDEVIRRANDTDYGLACSV
CHHHCCCCEECCEEEECCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHCCCCCCCCEEHH
WTKDLARAHRVAGQIEAGLVWVNSWFLRDLRTPFGGAKQSGIGREGGVHSLEFYTEQKNI
HHHHHHHHHHHHCCHHCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCE
CIKL
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]