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The map label for this gene is nahR1 [H]

Identifier: 119898710

GI number: 119898710

Start: 2672763

End: 2673671

Strand: Reverse

Name: nahR1 [H]

Synonym: azo2419

Alternate gene names: 119898710

Gene position: 2673671-2672763 (Counterclockwise)

Preceding gene: 119898718

Following gene: 119898708

Centisome position: 61.1

GC content: 68.54

Gene sequence:

>909_bases
GTGCAGTCACTGGAGGTACGCCTGCTGACGGTGTTCGACGAGATTTACAAGACGCGCAGCGTGACCCGCGCGGCCGACAA
CCTGGGCCTGGGCCAGCCGGCGGTGAGCATTGCGCTGGGCAAGCTGCGCGAGCACTTCGGCGATCCGCTGTTCGTGCGCA
CCTCCACCGGCATGGAGCCGACGCCGCTCGGCGAGGAGCTGGTGCAGCCGATCCGTGCGGCGCTGGACGCGCTGGCCGCG
GCGCTGGGCCGGCGCACCGCGTTCGATCCGTCTTCCGCGCAGCGCAGTTTCCGCATCTGCATGACCGACATCAGCCAGTT
GGTGCTGCTGCCGCGGTTGTGGGCGCACCTGCGCGCCACCGCGCCGGGCATCCGGATCGACATCGCCCACCTCTCCACCG
AAACGGCTAAGATGCTGGAGGCGGGTGAGGCGGACCTTGCGCTCGGCTTCATTCCGCAGCTGGAGGCCGGGTTCTACCAG
CAGGCGCTGTTCCGCCAGCGCTACGTGTGCATGGCCAATGCGGACCACCCGCGAATACGCGAGACGCTGAGCCTGGCCCA
GTTCGAGGCCGAGGAACATGCGGTGGTGAGCAGTTCCGGCACCGGCCACCTGATCCTCGACCGCGAGATCGCGCGCCAGA
ACATCAGCCGGCGGGTGGCGCTGGCGGTGCCCAACTTCCTCGGCGTCGCCTTCGTGGTGGAGCACACCGATCTGCTGGTG
ACGATTCCGGCCCGGCTGGCCGAAGTGCTTGCGGGGCGGGGGCGCTTCCGGACCTTTCCGGTGCCGTTCGAGCTACCGGA
TTACGCGGTCAAGCAGCACTGGCACGAGCGCTATCACCACGATCCCGGCAATCGCTGGCTGCGCCGGCTGATTTCGGACC
TGTTGTCCGCGCCAGTGGCAACGCCCTGA

Upstream 100 bases:

>100_bases
GCTTTCGTTGTGGTAGGCGAACTCTACGGATCGATGGATAATTGATCCATTCAATGCCGTTAATTCATTGCATTCGATAA
TCGAATAAAGGGGGCGAGCC

Downstream 100 bases:

>100_bases
TCAGGCGCGCGGCCGTAGCCAGTGGGCGGCGACGTCGACCATGCGGTTGGCGAAACCCCATTCGTTGTCGAACCACACCA
TGAGATTGAGCAGCCGCGGG

Product: putative LysR-type transcriptional regulator NahR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQSLEVRLLTVFDEIYKTRSVTRAADNLGLGQPAVSIALGKLREHFGDPLFVRTSTGMEPTPLGEELVQPIRAALDALAA
ALGRRTAFDPSSAQRSFRICMTDISQLVLLPRLWAHLRATAPGIRIDIAHLSTETAKMLEAGEADLALGFIPQLEAGFYQ
QALFRQRYVCMANADHPRIRETLSLAQFEAEEHAVVSSSGTGHLILDREIARQNISRRVALAVPNFLGVAFVVEHTDLLV
TIPARLAEVLAGRGRFRTFPVPFELPDYAVKQHWHERYHHDPGNRWLRRLISDLLSAPVATP

Sequences:

>Translated_302_residues
MQSLEVRLLTVFDEIYKTRSVTRAADNLGLGQPAVSIALGKLREHFGDPLFVRTSTGMEPTPLGEELVQPIRAALDALAA
ALGRRTAFDPSSAQRSFRICMTDISQLVLLPRLWAHLRATAPGIRIDIAHLSTETAKMLEAGEADLALGFIPQLEAGFYQ
QALFRQRYVCMANADHPRIRETLSLAQFEAEEHAVVSSSGTGHLILDREIARQNISRRVALAVPNFLGVAFVVEHTDLLV
TIPARLAEVLAGRGRFRTFPVPFELPDYAVKQHWHERYHHDPGNRWLRRLISDLLSAPVATP
>Mature_302_residues
MQSLEVRLLTVFDEIYKTRSVTRAADNLGLGQPAVSIALGKLREHFGDPLFVRTSTGMEPTPLGEELVQPIRAALDALAA
ALGRRTAFDPSSAQRSFRICMTDISQLVLLPRLWAHLRATAPGIRIDIAHLSTETAKMLEAGEADLALGFIPQLEAGFYQ
QALFRQRYVCMANADHPRIRETLSLAQFEAEEHAVVSSSGTGHLILDREIARQNISRRVALAVPNFLGVAFVVEHTDLLV
TIPARLAEVLAGRGRFRTFPVPFELPDYAVKQHWHERYHHDPGNRWLRRLISDLLSAPVATP

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=298, Percent_Identity=28.8590604026846, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786820, Length=250, Percent_Identity=26, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790147, Length=299, Percent_Identity=22.742474916388, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081766, Length=290, Percent_Identity=23.1034482758621, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI157672245, Length=244, Percent_Identity=25.8196721311475, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33592; Mature: 33592

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLEVRLLTVFDEIYKTRSVTRAADNLGLGQPAVSIALGKLREHFGDPLFVRTSTGMEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
TPLGEELVQPIRAALDALAAALGRRTAFDPSSAQRSFRICMTDISQLVLLPRLWAHLRAT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APGIRIDIAHLSTETAKMLEAGEADLALGFIPQLEAGFYQQALFRQRYVCMANADHPRIR
CCCCEEEEEHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHEECCCCCHHHH
ETLSLAQFEAEEHAVVSSSGTGHLILDREIARQNISRRVALAVPNFLGVAFVVEHTDLLV
HHHHHHHHHHHHHEEEECCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHEECCCEEE
TIPARLAEVLAGRGRFRTFPVPFELPDYAVKQHWHERYHHDPGNRWLRRLISDLLSAPVA
EHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
TP
CC
>Mature Secondary Structure
MQSLEVRLLTVFDEIYKTRSVTRAADNLGLGQPAVSIALGKLREHFGDPLFVRTSTGMEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
TPLGEELVQPIRAALDALAAALGRRTAFDPSSAQRSFRICMTDISQLVLLPRLWAHLRAT
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APGIRIDIAHLSTETAKMLEAGEADLALGFIPQLEAGFYQQALFRQRYVCMANADHPRIR
CCCCEEEEEHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHEECCCCCHHHH
ETLSLAQFEAEEHAVVSSSGTGHLILDREIARQNISRRVALAVPNFLGVAFVVEHTDLLV
HHHHHHHHHHHHHEEEECCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHEECCCEEE
TIPARLAEVLAGRGRFRTFPVPFELPDYAVKQHWHERYHHDPGNRWLRRLISDLLSAPVA
EHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
TP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]