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The map label for this gene is gapB [H]

Identifier: 119898709

GI number: 119898709

Start: 2671716

End: 2672762

Strand: Direct

Name: gapB [H]

Synonym: azo2418

Alternate gene names: 119898709

Gene position: 2671716-2672762 (Clockwise)

Preceding gene: 119898706

Following gene: 119898711

Centisome position: 61.05

GC content: 68.77

Gene sequence:

>1047_bases
TTGCCCACCGACTCCTTCGCCACCCCGCTGCGGCTAGCGATCAACGGCTACGGCCGCATCGGCCGCTGCTTCCTGCGCGC
GCTGCGCGAGTCCGGGCGGCGCGACGCCTTTCGCGTGGTAGCAATCAACGAGCCTGCCGACCTCGCCAGCATCGCCTACC
TCACCCGTTTCGATTCGACCCACGGCCGCTTTCCGGGCCGGGTGGATGCCGACGAGGACAGCCTGCTGATCGACGGCGAG
CGGATCGCGGTGAGTCACGCCACCACGCCGGAAGCGGTGGATTGGGCCGGGCTGGAGATCGACCTGGTGGTGGAGTGCTC
AGGCCAGTACGGCGACCGCGCCGGCCTTACGCGTTTTCTCGACGCGGGCTGTCCGCGCCTGCTGCTGTCCCACCCCGCGA
ACAGCGCCGCCGACGTAGACGCCACCATCGTCCATGGCATCAACCAGCACCTGCTGCGCGGCCACGAGCGCATCGTCTCC
AACGCCTCGTGCACCACCAACGCGGTCGTACCGGTGCTCGACCTGCTGCACGCCGAACTCGGGCTGGAGCAGGTGTTGCT
GACCACGCTGCACTCGGTCATGAACGACCAGCCGCTGATCGACGGCTACCACCACTCCGACCTACGCCGCACGCGCTCGG
CGATGCAGTCGATCATTCCGGTATCGACCGGGCTGGCACGCGGCGTGGAGCGCCTGCTGCCGGGGCTTGCCGGCCGCGTG
CAGGCCAAGGCCATCCGGGTGCCGACGCACAACGTGTCCGCGATCGACCTGGTGCTCGCGCTGGAACGCGACACCGACGC
CGGACAGGTCAACCGCCTGCTGCGCGATGCCGCCGCGGGGCCTTATGCCGGACTGCTCGCCTACAGCGACGACCCCCATG
CTTCGATCGACTTCAACCACGACCCGCATTCGGCCATCGTGGATGGCGCCCAGACGCGCATGAACGGCCCGCGGCTGCTC
AATCTCATGGTGTGGTTCGACAACGAATGGGGTTTCGCCAACCGCATGGTCGACGTCGCCGCCCACTGGCTACGGCCGCG
CGCCTGA

Upstream 100 bases:

>100_bases
GTCCGGCACGACGCGGACATTGCCGCGGAGGCGTTAGAATCGGCGGCTCCCACCCGCCCCGCCTTCCGCCCAGACCGTGC
CGCCGTCCGCTCCCTCATCC

Downstream 100 bases:

>100_bases
TCAGGGCGTTGCCACTGGCGCGGACAACAGGTCCGAAATCAGCCGGCGCAGCCAGCGATTGCCGGGATCGTGGTGATAGC
GCTCGTGCCAGTGCTGCTTG

Product: putative D-erythrose 4-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPTDSFATPLRLAINGYGRIGRCFLRALRESGRRDAFRVVAINEPADLASIAYLTRFDSTHGRFPGRVDADEDSLLIDGE
RIAVSHATTPEAVDWAGLEIDLVVECSGQYGDRAGLTRFLDAGCPRLLLSHPANSAADVDATIVHGINQHLLRGHERIVS
NASCTTNAVVPVLDLLHAELGLEQVLLTTLHSVMNDQPLIDGYHHSDLRRTRSAMQSIIPVSTGLARGVERLLPGLAGRV
QAKAIRVPTHNVSAIDLVLALERDTDAGQVNRLLRDAAAGPYAGLLAYSDDPHASIDFNHDPHSAIVDGAQTRMNGPRLL
NLMVWFDNEWGFANRMVDVAAHWLRPRA

Sequences:

>Translated_348_residues
MPTDSFATPLRLAINGYGRIGRCFLRALRESGRRDAFRVVAINEPADLASIAYLTRFDSTHGRFPGRVDADEDSLLIDGE
RIAVSHATTPEAVDWAGLEIDLVVECSGQYGDRAGLTRFLDAGCPRLLLSHPANSAADVDATIVHGINQHLLRGHERIVS
NASCTTNAVVPVLDLLHAELGLEQVLLTTLHSVMNDQPLIDGYHHSDLRRTRSAMQSIIPVSTGLARGVERLLPGLAGRV
QAKAIRVPTHNVSAIDLVLALERDTDAGQVNRLLRDAAAGPYAGLLAYSDDPHASIDFNHDPHSAIVDGAQTRMNGPRLL
NLMVWFDNEWGFANRMVDVAAHWLRPRA
>Mature_347_residues
PTDSFATPLRLAINGYGRIGRCFLRALRESGRRDAFRVVAINEPADLASIAYLTRFDSTHGRFPGRVDADEDSLLIDGER
IAVSHATTPEAVDWAGLEIDLVVECSGQYGDRAGLTRFLDAGCPRLLLSHPANSAADVDATIVHGINQHLLRGHERIVSN
ASCTTNAVVPVLDLLHAELGLEQVLLTTLHSVMNDQPLIDGYHHSDLRRTRSAMQSIIPVSTGLARGVERLLPGLAGRVQ
AKAIRVPTHNVSAIDLVLALERDTDAGQVNRLLRDAAAGPYAGLLAYSDDPHASIDFNHDPHSAIVDGAQTRMNGPRLLN
LMVWFDNEWGFANRMVDVAAHWLRPRA

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=36.7164179104478, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI7657116, Length=337, Percent_Identity=37.0919881305638, Blast_Score=228, Evalue=8e-60,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=51.063829787234, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=35.1351351351351, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=37.4631268436578, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=37.1681415929204, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32566163, Length=343, Percent_Identity=36.734693877551, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=36.8731563421829, Blast_Score=222, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6322409, Length=337, Percent_Identity=38.5756676557863, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=36.6071428571429, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6321631, Length=337, Percent_Identity=36.4985163204748, Blast_Score=244, Evalue=1e-65,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=34.8348348348348, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=34.8348348348348, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=34.5345345345345, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=34.5345345345345, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=32.5301204819277, Blast_Score=212, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 37922; Mature: 37791

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDSFATPLRLAINGYGRIGRCFLRALRESGRRDAFRVVAINEPADLASIAYLTRFDST
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
HGRFPGRVDADEDSLLIDGERIAVSHATTPEAVDWAGLEIDLVVECSGQYGDRAGLTRFL
CCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHH
DAGCPRLLLSHPANSAADVDATIVHGINQHLLRGHERIVSNASCTTNAVVPVLDLLHAEL
HCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GLEQVLLTTLHSVMNDQPLIDGYHHSDLRRTRSAMQSIIPVSTGLARGVERLLPGLAGRV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAKAIRVPTHNVSAIDLVLALERDTDAGQVNRLLRDAAAGPYAGLLAYSDDPHASIDFNH
EEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCC
DPHSAIVDGAQTRMNGPRLLNLMVWFDNEWGFANRMVDVAAHWLRPRA
CCCHHHHCCHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PTDSFATPLRLAINGYGRIGRCFLRALRESGRRDAFRVVAINEPADLASIAYLTRFDST
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
HGRFPGRVDADEDSLLIDGERIAVSHATTPEAVDWAGLEIDLVVECSGQYGDRAGLTRFL
CCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHH
DAGCPRLLLSHPANSAADVDATIVHGINQHLLRGHERIVSNASCTTNAVVPVLDLLHAEL
HCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
GLEQVLLTTLHSVMNDQPLIDGYHHSDLRRTRSAMQSIIPVSTGLARGVERLLPGLAGRV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAKAIRVPTHNVSAIDLVLALERDTDAGQVNRLLRDAAAGPYAGLLAYSDDPHASIDFNH
EEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCC
DPHSAIVDGAQTRMNGPRLLNLMVWFDNEWGFANRMVDVAAHWLRPRA
CCCHHHHCCHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA