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The map label for this gene is arsB

Identifier: 119898645

GI number: 119898645

Start: 2593338

End: 2594402

Strand: Direct

Name: arsB

Synonym: azo2354

Alternate gene names: NA

Gene position: 2593338-2594402 (Clockwise)

Preceding gene: 119898644

Following gene: 119898646

Centisome position: 59.26

GC content: 66.01

Gene sequence:

>1065_bases
ATGTCCCAGTACGAAATGACCGCCCCCGCGCCTGTTCCGGCGCCGATGAGCGTGTTCGAGCGTTATCTCACCGTGTGGGT
CTTCCTCTGCATCGTCGCCGGCATCGCCCTCGGGCAGTGGCTGCCCGGCCTGTTCCAGGCTGTCGGGCGGATGGAAGTGG
CGCAGGTGAATCTGCCGGTGGGCCTGCTGATCTGGGTGATGATCATCCCGATGCTGGTCAAGGTGGATTTCGGCGCGCTG
CACGAGGTACGCGCCCATGTGCGCGGCATCGGCGTCACGCTGTTCGTCAATTGGCTGGTCAAGCCCTTCTCGATGGCCTT
CCTCGGCTGGTTGTTCATCCGCCAGCTGTTCGCCCCCATGCTGCCGGCCGACCAGCTCGACAGCTACATCGCCGGCCTCA
TCCTGCTTGCTGCCGCGCCCTGCACCGCGATGGTGTTCGTGTGGAGCCGGCTGACCAACGGCCACCCGTTGTTCACGCTG
TCGCAGGTGGCGCTCAACGACACCATCATGGTGTTCGCGTTCGCGCCGCTGGTGGGGCTGCTGCTCGGCATCTCGGCGAT
CAGCGTGCCGTGGGACACGCTGCTGACCTCGGTGGTGCTCTACATCGTGATTCCAGTGGTGCTCGCGCAGCTGTGGCGCC
GCCGCCTGCTCGCGCGCGGCCAGGCGGCCTTCGACGCGGCGATGGAAAAGATCGGGCCGTGGTCGATCGCGGCGCTATTG
CTCACGCTGGTGCTGCTGTTCGCCTTCCAGGGCGAAGCGATCCTGCGCCAGCCGCTGGTGATCGCGCTGCTCGCCGTGCC
TATCCTGATTCAGGTGCTGTTCAATTCCGCCCTCGCCTACTGGCTCAACCGCAAGGTCGGCGAGCAGCACAATGTGGCCT
GCCCTTCGGCCCTGATCGGCGCCTCCAACTTCTTCGAACTCGCGGTGGCCGCGGCCATCAGCCTGTTCGGTTTCGAATCC
GGCGCCGCGCTCGCCACCGTGGTCGGCGTGCTGATCGAGGTGCCGGTGATGCTGCTGGTGGTCCGCGTCGTCAATGCATC
CAAGGGCTGGTACGAAGCCCGCTGA

Upstream 100 bases:

>100_bases
GCACGGCGAACCGCTGGAGAGCTTCGTCGCGGTACGCGACGACATCCGCGCCCGCCTGGTGCCCGCGGTGCGCGCCGCGC
TCGGTCTGTAGGAAGCCGCC

Downstream 100 bases:

>100_bases
TCCAGGAGACAAGCATGAAAAAGCTCGAAGTGTTCGATCCCGCGATGTGCTGTTCCACCGGCGTGTGCGGGGTGGATGTC
GATCCGGTGCTGGTGCAGTT

Product: putative arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSQYEMTAPAPVPAPMSVFERYLTVWVFLCIVAGIALGQWLPGLFQAVGRMEVAQVNLPVGLLIWVMIIPMLVKVDFGAL
HEVRAHVRGIGVTLFVNWLVKPFSMAFLGWLFIRQLFAPMLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGHPLFTL
SQVALNDTIMVFAFAPLVGLLLGISAISVPWDTLLTSVVLYIVIPVVLAQLWRRRLLARGQAAFDAAMEKIGPWSIAALL
LTLVLLFAFQGEAILRQPLVIALLAVPILIQVLFNSALAYWLNRKVGEQHNVACPSALIGASNFFELAVAAAISLFGFES
GAALATVVGVLIEVPVMLLVVRVVNASKGWYEAR

Sequences:

>Translated_354_residues
MSQYEMTAPAPVPAPMSVFERYLTVWVFLCIVAGIALGQWLPGLFQAVGRMEVAQVNLPVGLLIWVMIIPMLVKVDFGAL
HEVRAHVRGIGVTLFVNWLVKPFSMAFLGWLFIRQLFAPMLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGHPLFTL
SQVALNDTIMVFAFAPLVGLLLGISAISVPWDTLLTSVVLYIVIPVVLAQLWRRRLLARGQAAFDAAMEKIGPWSIAALL
LTLVLLFAFQGEAILRQPLVIALLAVPILIQVLFNSALAYWLNRKVGEQHNVACPSALIGASNFFELAVAAAISLFGFES
GAALATVVGVLIEVPVMLLVVRVVNASKGWYEAR
>Mature_353_residues
SQYEMTAPAPVPAPMSVFERYLTVWVFLCIVAGIALGQWLPGLFQAVGRMEVAQVNLPVGLLIWVMIIPMLVKVDFGALH
EVRAHVRGIGVTLFVNWLVKPFSMAFLGWLFIRQLFAPMLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGHPLFTLS
QVALNDTIMVFAFAPLVGLLLGISAISVPWDTLLTSVVLYIVIPVVLAQLWRRRLLARGQAAFDAAMEKIGPWSIAALLL
TLVLLFAFQGEAILRQPLVIALLAVPILIQVLFNSALAYWLNRKVGEQHNVACPSALIGASNFFELAVAAAISLFGFESG
AALATVVGVLIEVPVMLLVVRVVNASKGWYEAR

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=347, Percent_Identity=25.0720461095101, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38545; Mature: 38414

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SQYEMTAPAPVPAPMSVFERYLTVWVFLCIVAGIALGQWLPGLFQAVGRMEVAQVNLPV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCH
GLLIWVMIIPMLVKVDFGALHEVRAHVRGIGVTLFVNWLVKPFSMAFLGWLFIRQLFAPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGHPLFTLSQVALNDTIMVFAFAPLVGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLGISAISVPWDTLLTSVVLYIVIPVVLAQLWRRRLLARGQAAFDAAMEKIGPWSIAALL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
LTLVLLFAFQGEAILRQPLVIALLAVPILIQVLFNSALAYWLNRKVGEQHNVACPSALIG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHC
ASNFFELAVAAAISLFGFESGAALATVVGVLIEVPVMLLVVRVVNASKGWYEAR
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]