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The map label for this gene is kup

Identifier: 119898563

GI number: 119898563

Start: 2488755

End: 2490671

Strand: Reverse

Name: kup

Synonym: azo2272

Alternate gene names: 119898563

Gene position: 2490671-2488755 (Counterclockwise)

Preceding gene: 119898564

Following gene: 119898561

Centisome position: 56.92

GC content: 66.82

Gene sequence:

>1917_bases
ATGCAGGTTGAACACGAGGTTGCAACCGAAGGCGGGCAGGCTCCGGCCTCCTCCGGCCACCGCAAGGGCATCGCAGGTCT
GGCCGTGGCCGCGATCGGTGTCGTCTATGGCGACATCGGCACCAGTCCACTCTATACGCTGAAAGAGGTATTCAACGGCC
CCCATGCGGTGCCGGTGAACGAGGCCAACGTCTACGGCATCCTCTCGCTGGTGTTCTGGGCGCTGGTCACCGTGGTGTCG
GCCAAGTACGTGGTCTTCATCACCCGCGCCGACAACCGCGGCGAGGGCGGCATCATGGCGCTTACCTCGCTCGCGTTGCG
CGTCGTTCAGCCCGGCCGGCGAGCCTGGTGGCTGTCGGTGCTGGGGGTGTTCGGCGCCGCGCTGTTCTACGGCGACGGCA
TGATCACGCCGGCAATCTCGGTGCTCTCCGCGGTGGAAGGCCTGGAGGTGGCGACGCCGGCGTTCAAACCCTTCGTGATC
CCGATCGCGCTCGTGGTGCTGGTGGGGCTGTTCGTGATGCAGCGCCGCGGCACCGGCAGCGTGGGGGCCATCTTCGGGCC
GGTCATGGTGTGCTGGTTCCTGGTGCTGGCGGTGCTCGGCATCAACGGCATCACGCTGCACCCGGAGATCATCGGTGCGC
TCGACCCGCGCTGGGCCGCGCGCTTCTTCATCGACCAGCCGCTGATCGGCTGGCTTGCGCTCGGCGCGGTGGTGCTGGCG
ATTACCGGGGGCGAGGCGCTGTACGCCGACATGGGCCACTTCGGCCGCCGCCCGATCAAGCTGGCGTGGTTCAGCCTGGT
ATTCCCGGCGCTCTATCTCAACTACCTCGGCCAGGGCGCGCTGATCCTCGACCACCCGGACAACGTCCGCAACCCGTTCT
ACATGCTGGTGCCGGACGCGCTGGTCTATCCGATGGTGGGGATGGCGACGCTGGCCACGATCATCGCCAGCCAGGCCGTG
ATTTCCGGCGCGTTCTCGCTCACCCGGCAGGCCATCCAGCTTGGCTACGCGCCGCGCATGCAGACGCTGCACACTTCCGA
GCACGAGATCGGCCAGATCTACGTGCCGGGCGTGAACTGGATGCTGCTCGGCGCTGTGGTGGCGCTGGTGGTGGGCTTCC
AGTCGTCCAGCGCGCTGGCGTCGGCCTACGGCATCGCCGTGACGCTGACGATGATGATCGACACCGTGCTTGCCTTCGTG
GTGGTGCGCAGCCTGTGGAAGTGGGGACGGGCGAAGGCAGTGTTGTTCCTCGTCGTGTTCCTTGCAGTGGATATCGCGTT
CTTCTCCGCGACCACGGTCAAGATCTTCGCGGGCGGCTGGTTCCCGCTGCTGATCGGTGCGGCGATCTTCACGTTGCTGC
GCACCTGGAAGCGCGGCCGCAGCCTGCTCAACGAGCGCATCCGCAGCGACACGATGCCGCTCGACATCTTCATCCAGTCG
ATGTTCCAGAGCCCGCCGCCGCGCGTCGAAGGCACCGCGGTGTTCATGACGACCTGGCTGGACGGCGTGCCGCGCGCGTT
GCTGCACAACCTGATCCACAACAAGGTGCTGCACGAGCGGGTGGTGCTGCTGCGGGTGGACACCGCGGACGTGCCGCACG
TGCCGGAGGGCGAGCGGGTCGAGGTGGAGGAGATCGACTACGGCTTTTACCGCGTGCGGGTGCACTACGGCTTCAAGGAC
GATCCGGACATTCCCGCTGCGCTCGGGCTCTGTGCGCAGCGCGGCTTGCCGTTCGACATGATGGAGACCTCGTTCTTCCT
CGGCCGCGAAACCCTGGTGTCGCGCGTGGGGTCCGGCATGCCGCAGTGGCGCGAGAAGCTCTTCATCCTGCTGTTCCGCA
ACGCGGGCAGCGCGGCGGACTACTTCTGCATTCCGCCCAACCGGGTGGTGGAACTGGGTACCCAGGTCGAGCTGTAG

Upstream 100 bases:

>100_bases
AAAACGCATGGCGCGCCAGCACGCTGTTAAGTGAAGCTGTCAGTATCCCGCAGCGGGACCCGGCATCTCTCGCCAGGTCT
TTGATAATCAGGGGTTGTGG

Downstream 100 bases:

>100_bases
CGCAGGCGTCGGCCGACGCCTGCGCTGGCGGGCGTCGTCAGCCGCACACGGCGGCGAGCATCTCCTGCTTGCTGCTGCGC
GCGGCATCGAGCAGCGCGTC

Product: putative potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MQVEHEVATEGGQAPASSGHRKGIAGLAVAAIGVVYGDIGTSPLYTLKEVFNGPHAVPVNEANVYGILSLVFWALVTVVS
AKYVVFITRADNRGEGGIMALTSLALRVVQPGRRAWWLSVLGVFGAALFYGDGMITPAISVLSAVEGLEVATPAFKPFVI
PIALVVLVGLFVMQRRGTGSVGAIFGPVMVCWFLVLAVLGINGITLHPEIIGALDPRWAARFFIDQPLIGWLALGAVVLA
ITGGEALYADMGHFGRRPIKLAWFSLVFPALYLNYLGQGALILDHPDNVRNPFYMLVPDALVYPMVGMATLATIIASQAV
ISGAFSLTRQAIQLGYAPRMQTLHTSEHEIGQIYVPGVNWMLLGAVVALVVGFQSSSALASAYGIAVTLTMMIDTVLAFV
VVRSLWKWGRAKAVLFLVVFLAVDIAFFSATTVKIFAGGWFPLLIGAAIFTLLRTWKRGRSLLNERIRSDTMPLDIFIQS
MFQSPPPRVEGTAVFMTTWLDGVPRALLHNLIHNKVLHERVVLLRVDTADVPHVPEGERVEVEEIDYGFYRVRVHYGFKD
DPDIPAALGLCAQRGLPFDMMETSFFLGRETLVSRVGSGMPQWREKLFILLFRNAGSAADYFCIPPNRVVELGTQVEL

Sequences:

>Translated_638_residues
MQVEHEVATEGGQAPASSGHRKGIAGLAVAAIGVVYGDIGTSPLYTLKEVFNGPHAVPVNEANVYGILSLVFWALVTVVS
AKYVVFITRADNRGEGGIMALTSLALRVVQPGRRAWWLSVLGVFGAALFYGDGMITPAISVLSAVEGLEVATPAFKPFVI
PIALVVLVGLFVMQRRGTGSVGAIFGPVMVCWFLVLAVLGINGITLHPEIIGALDPRWAARFFIDQPLIGWLALGAVVLA
ITGGEALYADMGHFGRRPIKLAWFSLVFPALYLNYLGQGALILDHPDNVRNPFYMLVPDALVYPMVGMATLATIIASQAV
ISGAFSLTRQAIQLGYAPRMQTLHTSEHEIGQIYVPGVNWMLLGAVVALVVGFQSSSALASAYGIAVTLTMMIDTVLAFV
VVRSLWKWGRAKAVLFLVVFLAVDIAFFSATTVKIFAGGWFPLLIGAAIFTLLRTWKRGRSLLNERIRSDTMPLDIFIQS
MFQSPPPRVEGTAVFMTTWLDGVPRALLHNLIHNKVLHERVVLLRVDTADVPHVPEGERVEVEEIDYGFYRVRVHYGFKD
DPDIPAALGLCAQRGLPFDMMETSFFLGRETLVSRVGSGMPQWREKLFILLFRNAGSAADYFCIPPNRVVELGTQVEL
>Mature_638_residues
MQVEHEVATEGGQAPASSGHRKGIAGLAVAAIGVVYGDIGTSPLYTLKEVFNGPHAVPVNEANVYGILSLVFWALVTVVS
AKYVVFITRADNRGEGGIMALTSLALRVVQPGRRAWWLSVLGVFGAALFYGDGMITPAISVLSAVEGLEVATPAFKPFVI
PIALVVLVGLFVMQRRGTGSVGAIFGPVMVCWFLVLAVLGINGITLHPEIIGALDPRWAARFFIDQPLIGWLALGAVVLA
ITGGEALYADMGHFGRRPIKLAWFSLVFPALYLNYLGQGALILDHPDNVRNPFYMLVPDALVYPMVGMATLATIIASQAV
ISGAFSLTRQAIQLGYAPRMQTLHTSEHEIGQIYVPGVNWMLLGAVVALVVGFQSSSALASAYGIAVTLTMMIDTVLAFV
VVRSLWKWGRAKAVLFLVVFLAVDIAFFSATTVKIFAGGWFPLLIGAAIFTLLRTWKRGRSLLNERIRSDTMPLDIFIQS
MFQSPPPRVEGTAVFMTTWLDGVPRALLHNLIHNKVLHERVVLLRVDTADVPHVPEGERVEVEEIDYGFYRVRVHYGFKD
DPDIPAALGLCAQRGLPFDMMETSFFLGRETLVSRVGSGMPQWREKLFILLFRNAGSAADYFCIPPNRVVELGTQVEL

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=622, Percent_Identity=50.1607717041801, Blast_Score=630, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_AZOSB (A1K7T4)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_933776.1
- STRING:   A1K7T4
- GeneID:   4607323
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2272
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   FVIRYSW
- PhylomeDB:   A1K7T4
- ProtClustDB:   CLSK766690
- BioCyc:   ASP62928:AZO2272-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 69451; Mature: 69451

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1841a440)-; HASH(0x1c422890)-; HASH(0x1ccad32c)-; HASH(0x1a10f05c)-; HASH(0x181fbc34)-; HASH(0x1d23428c)-; HASH(0x1d2340a0)-; HASH(0x1d2239cc)-; HASH(0x1d21edb0)-; HASH(0x1d25b2b0)-; HASH(0x1ce220bc)-; HASH(0x1c31a8a0)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVEHEVATEGGQAPASSGHRKGIAGLAVAAIGVVYGDIGTSPLYTLKEVFNGPHAVPVN
CCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
EANVYGILSLVFWALVTVVSAKYVVFITRADNRGEGGIMALTSLALRVVQPGRRAWWLSV
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LGVFGAALFYGDGMITPAISVLSAVEGLEVATPAFKPFVIPIALVVLVGLFVMQRRGTGS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VGAIFGPVMVCWFLVLAVLGINGITLHPEIIGALDPRWAARFFIDQPLIGWLALGAVVLA
HHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHH
ITGGEALYADMGHFGRRPIKLAWFSLVFPALYLNYLGQGALILDHPDNVRNPFYMLVPDA
EECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCHH
LVYPMVGMATLATIIASQAVISGAFSLTRQAIQLGYAPRMQTLHTSEHEIGQIYVPGVNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEECCCHH
MLLGAVVALVVGFQSSSALASAYGIAVTLTMMIDTVLAFVVVRSLWKWGRAKAVLFLVVF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LAVDIAFFSATTVKIFAGGWFPLLIGAAIFTLLRTWKRGRSLLNERIRSDTMPLDIFIQS
HHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
MFQSPPPRVEGTAVFMTTWLDGVPRALLHNLIHNKVLHERVVLLRVDTADVPHVPEGERV
HHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCEE
EVEEIDYGFYRVRVHYGFKDDPDIPAALGLCAQRGLPFDMMETSFFLGRETLVSRVGSGM
EHEEECCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
PQWREKLFILLFRNAGSAADYFCIPPNRVVELGTQVEL
HHHHHHEEEEEEECCCCCCCEEECCCHHHHHCCCCCCH
>Mature Secondary Structure
MQVEHEVATEGGQAPASSGHRKGIAGLAVAAIGVVYGDIGTSPLYTLKEVFNGPHAVPVN
CCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
EANVYGILSLVFWALVTVVSAKYVVFITRADNRGEGGIMALTSLALRVVQPGRRAWWLSV
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LGVFGAALFYGDGMITPAISVLSAVEGLEVATPAFKPFVIPIALVVLVGLFVMQRRGTGS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VGAIFGPVMVCWFLVLAVLGINGITLHPEIIGALDPRWAARFFIDQPLIGWLALGAVVLA
HHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHH
ITGGEALYADMGHFGRRPIKLAWFSLVFPALYLNYLGQGALILDHPDNVRNPFYMLVPDA
EECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCHH
LVYPMVGMATLATIIASQAVISGAFSLTRQAIQLGYAPRMQTLHTSEHEIGQIYVPGVNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEECCCHH
MLLGAVVALVVGFQSSSALASAYGIAVTLTMMIDTVLAFVVVRSLWKWGRAKAVLFLVVF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LAVDIAFFSATTVKIFAGGWFPLLIGAAIFTLLRTWKRGRSLLNERIRSDTMPLDIFIQS
HHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
MFQSPPPRVEGTAVFMTTWLDGVPRALLHNLIHNKVLHERVVLLRVDTADVPHVPEGERV
HHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCEE
EVEEIDYGFYRVRVHYGFKDDPDIPAALGLCAQRGLPFDMMETSFFLGRETLVSRVGSGM
EHEEECCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
PQWREKLFILLFRNAGSAADYFCIPPNRVVELGTQVEL
HHHHHHEEEEEEECCCCCCCEEECCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA