Click here to switch to the map view.

The map label for this gene is etf1 [C]

Identifier: 119898442

GI number: 119898442

Start: 2354316

End: 2355959

Strand: Direct

Name: etf1 [C]

Synonym: azo2151

Alternate gene names: 119898442

Gene position: 2354316-2355959 (Clockwise)

Preceding gene: 119898438

Following gene: 119898450

Centisome position: 53.8

GC content: 66.06

Gene sequence:

>1644_bases
ATGGAACGTGAGTCGATGGAATTCGACGTACTGATCGTCGGCGGCGGCCCTGCGGGGCTGGCTGCGGCGATCCGTCTGAA
GCAACTGGCCGAAGCGAAGGGTCAGGACATCTCGGTGTGCCTGATCGAGAAAGGCGCCGAGATCGGCGCCCACATCCTGT
CCGGCGCGGTGATGGACCCCAGGGCACTGACCGAACTCTTTCCCGACTGGAAAGAGCGCGGCGCGCCGCTGAAGACGGCG
GTCACCGAGGACAAGGTGATCTTCCTCAACGAAACCGGCGGCCACACGGTCCCCAACAACCTGTTGCCCGACTGTTTCAT
CAACCACGGCAACTACATCGTCCGCCTCGGCAACGTTGCCAAGTGGCTCGGCGAGCAGGCCGAAGCGATGGGTGTCGAGG
TCTACCCAGGCTTTGCGGGCGCCGAAGTGCTGTACGACGAGGCCGGCGCGGTCAAGGGCGTCGCCACCGGCGACATGGGC
CTCAACCGCGACGGCACCCCGGGCCCCAACCATCAGTTGGGCATGGAGCTGCACGCGAAGTACACGCTGTTCGCCGAAGG
CTGTCGCGGCCATCTCGGCAAGCAGCTCGAGGCCAGATACCAATTGCGCGACGGCGTCGATCCGCAAACCTACGGCATCG
GCATCAAGGAGCTGTGGGAAGTGCCGGTGCAGAACCACCGCCCCGGCCTGGTGGTGCACACCGCAGGCTGGCCGCTGCCC
GCCGACACCTACGGCGGCGGCTTCGTCTATCACCTCGAGGACAACCTGGTCGCGGTCGGCTACGTGGTCGGCCTCAACTA
CAGCAATCCGCACCTGTCGCCGTTCGAGGAGATGCAGCGCTACAAGACGCATCCGGAAATCCGCAAATACCTGGAAGGCG
GCAAGCGCCTGGCCTATGGCGCCCGCGCGATCGCCGCCGGCGGCCTGCAGAGCCAGCCGCGCCTGGTGTTCCCGGGCGGT
GCGCTGATCGGCGACGACGCCGGCTTCCTCAACGCGGCCCGCATCAAGGGCAGCCATGCGGCGATCAAGAGCGGCATGCT
CGCCGCCGAAGCAGCCTTCGAGGCGGTGGGCGCCAACCGCCAGCGCGACGCGCTGACCGCCTACCCGTCCGCCTTCCAGG
ACTCCTGGCTGCACGCCGAACTCTACAAGACGCGCAACTTCAAGCCCTACATGAAAAAAGGCTTGTGGCTGGGCTCGCTG
CTGTTCGGCATCGACCAGAAGCTCTTCGGCGGCAAGGTGCCCTGGACGCTGCACAACACGGCCGACCACACGGCCTTGCG
CCCGGCCGCGGAGTGCCCGCGGATCGACTACCCGAAGCCGGACGGCAAGCTCAGCTTCGATCGTCTGTCCTCGGTGTTCC
TGTCCAACACCAACCACGAAGAAGAGCAGCCCTGCCACCTGCAGCTGAAGGACCCGGGCGTTCCGATCGCGGTCAACCTG
GCGAAGTACGACGCGCCTGAGCAGCGCTACTGCCCCGCGGGGGTGTACGAAATCGTCCGCGACGGCGAGAACAACGCGCC
GCGGCTGCAGATCAACGCGCAGAACTGCGTGCACTGCAAGACGTGCGACATCAAGGACCCCACGCAGAACATCAACTGGG
TGGTGCCGCAGGGCGGCGAAGGGCCGATCTACCAGGGGATGTAA

Upstream 100 bases:

>100_bases
GGCGTCGCTGCTGGGCCCGCGGAGAATCGCCAGCCCGCTGTATTACACTGTCGCCCGCCAAACAAAGACGATACAAGCAA
GCGAGTACGAGGAGAATTGG

Downstream 100 bases:

>100_bases
TCACCCCCTCCCGGTCTGCAAGACGGCGCCGCGCACTCCGCGGCGCCGTTTTTTTTGGCCTGCGCACCATACAGCCGCAC
TCACCACTCGTATCCCAGAC

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MERESMEFDVLIVGGGPAGLAAAIRLKQLAEAKGQDISVCLIEKGAEIGAHILSGAVMDPRALTELFPDWKERGAPLKTA
VTEDKVIFLNETGGHTVPNNLLPDCFINHGNYIVRLGNVAKWLGEQAEAMGVEVYPGFAGAEVLYDEAGAVKGVATGDMG
LNRDGTPGPNHQLGMELHAKYTLFAEGCRGHLGKQLEARYQLRDGVDPQTYGIGIKELWEVPVQNHRPGLVVHTAGWPLP
ADTYGGGFVYHLEDNLVAVGYVVGLNYSNPHLSPFEEMQRYKTHPEIRKYLEGGKRLAYGARAIAAGGLQSQPRLVFPGG
ALIGDDAGFLNAARIKGSHAAIKSGMLAAEAAFEAVGANRQRDALTAYPSAFQDSWLHAELYKTRNFKPYMKKGLWLGSL
LFGIDQKLFGGKVPWTLHNTADHTALRPAAECPRIDYPKPDGKLSFDRLSSVFLSNTNHEEEQPCHLQLKDPGVPIAVNL
AKYDAPEQRYCPAGVYEIVRDGENNAPRLQINAQNCVHCKTCDIKDPTQNINWVVPQGGEGPIYQGM

Sequences:

>Translated_547_residues
MERESMEFDVLIVGGGPAGLAAAIRLKQLAEAKGQDISVCLIEKGAEIGAHILSGAVMDPRALTELFPDWKERGAPLKTA
VTEDKVIFLNETGGHTVPNNLLPDCFINHGNYIVRLGNVAKWLGEQAEAMGVEVYPGFAGAEVLYDEAGAVKGVATGDMG
LNRDGTPGPNHQLGMELHAKYTLFAEGCRGHLGKQLEARYQLRDGVDPQTYGIGIKELWEVPVQNHRPGLVVHTAGWPLP
ADTYGGGFVYHLEDNLVAVGYVVGLNYSNPHLSPFEEMQRYKTHPEIRKYLEGGKRLAYGARAIAAGGLQSQPRLVFPGG
ALIGDDAGFLNAARIKGSHAAIKSGMLAAEAAFEAVGANRQRDALTAYPSAFQDSWLHAELYKTRNFKPYMKKGLWLGSL
LFGIDQKLFGGKVPWTLHNTADHTALRPAAECPRIDYPKPDGKLSFDRLSSVFLSNTNHEEEQPCHLQLKDPGVPIAVNL
AKYDAPEQRYCPAGVYEIVRDGENNAPRLQINAQNCVHCKTCDIKDPTQNINWVVPQGGEGPIYQGM
>Mature_547_residues
MERESMEFDVLIVGGGPAGLAAAIRLKQLAEAKGQDISVCLIEKGAEIGAHILSGAVMDPRALTELFPDWKERGAPLKTA
VTEDKVIFLNETGGHTVPNNLLPDCFINHGNYIVRLGNVAKWLGEQAEAMGVEVYPGFAGAEVLYDEAGAVKGVATGDMG
LNRDGTPGPNHQLGMELHAKYTLFAEGCRGHLGKQLEARYQLRDGVDPQTYGIGIKELWEVPVQNHRPGLVVHTAGWPLP
ADTYGGGFVYHLEDNLVAVGYVVGLNYSNPHLSPFEEMQRYKTHPEIRKYLEGGKRLAYGARAIAAGGLQSQPRLVFPGG
ALIGDDAGFLNAARIKGSHAAIKSGMLAAEAAFEAVGANRQRDALTAYPSAFQDSWLHAELYKTRNFKPYMKKGLWLGSL
LFGIDQKLFGGKVPWTLHNTADHTALRPAAECPRIDYPKPDGKLSFDRLSSVFLSNTNHEEEQPCHLQLKDPGVPIAVNL
AKYDAPEQRYCPAGVYEIVRDGENNAPRLQINAQNCVHCKTCDIKDPTQNINWVVPQGGEGPIYQGM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=558, Percent_Identity=57.7060931899642, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=331, Percent_Identity=30.2114803625378, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786227, Length=332, Percent_Identity=28.3132530120482, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082155, Length=373, Percent_Identity=25.7372654155496, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25144720, Length=558, Percent_Identity=55.5555555555556, Blast_Score=614, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6324932, Length=571, Percent_Identity=48.5113835376532, Blast_Score=503, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24652256, Length=556, Percent_Identity=58.4532374100719, Blast_Score=647, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 59565; Mature: 59565

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERESMEFDVLIVGGGPAGLAAAIRLKQLAEAKGQDISVCLIEKGAEIGAHILSGAVMDP
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCH
RALTELFPDWKERGAPLKTAVTEDKVIFLNETGGHTVPNNLLPDCFINHGNYIVRLGNVA
HHHHHHCCCHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHEECCCCEEEEECHHH
KWLGEQAEAMGVEVYPGFAGAEVLYDEAGAVKGVATGDMGLNRDGTPGPNHQLGMELHAK
HHHCCHHHHCCEEEECCCCCCHHEECCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEE
YTLFAEGCRGHLGKQLEARYQLRDGVDPQTYGIGIKELWEVPVQNHRPGLVVHTAGWPLP
EEEEECCHHHHCCHHHHHHHHHHCCCCCHHCCCCHHHHHHCCCCCCCCCEEEEECCCCCC
ADTYGGGFVYHLEDNLVAVGYVVGLNYSNPHLSPFEEMQRYKTHPEIRKYLEGGKRLAYG
CCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEECC
ARAIAAGGLQSQPRLVFPGGALIGDDAGFLNAARIKGSHAAIKSGMLAAEAAFEAVGANR
CHHHCCCCCCCCCEEEECCCCEEECCCCCCCCEEECCCHHHHHHCCHHHHHHHHHHCCCC
QRDALTAYPSAFQDSWLHAELYKTRNFKPYMKKGLWLGSLLFGIDQKLFGGKVPWTLHNT
CCCHHHHCCCHHHCCCHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCC
ADHTALRPAAECPRIDYPKPDGKLSFDRLSSVFLSNTNHEEEQPCHLQLKDPGVPIAVNL
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEE
AKYDAPEQRYCPAGVYEIVRDGENNAPRLQINAQNCVHCKTCDIKDPTQNINWVVPQGGE
HHCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEECCCC
GPIYQGM
CCCCCCC
>Mature Secondary Structure
MERESMEFDVLIVGGGPAGLAAAIRLKQLAEAKGQDISVCLIEKGAEIGAHILSGAVMDP
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCH
RALTELFPDWKERGAPLKTAVTEDKVIFLNETGGHTVPNNLLPDCFINHGNYIVRLGNVA
HHHHHHCCCHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHEECCCCEEEEECHHH
KWLGEQAEAMGVEVYPGFAGAEVLYDEAGAVKGVATGDMGLNRDGTPGPNHQLGMELHAK
HHHCCHHHHCCEEEECCCCCCHHEECCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEE
YTLFAEGCRGHLGKQLEARYQLRDGVDPQTYGIGIKELWEVPVQNHRPGLVVHTAGWPLP
EEEEECCHHHHCCHHHHHHHHHHCCCCCHHCCCCHHHHHHCCCCCCCCCEEEEECCCCCC
ADTYGGGFVYHLEDNLVAVGYVVGLNYSNPHLSPFEEMQRYKTHPEIRKYLEGGKRLAYG
CCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEECC
ARAIAAGGLQSQPRLVFPGGALIGDDAGFLNAARIKGSHAAIKSGMLAAEAAFEAVGANR
CHHHCCCCCCCCCEEEECCCCEEECCCCCCCCEEECCCHHHHHHCCHHHHHHHHHHCCCC
QRDALTAYPSAFQDSWLHAELYKTRNFKPYMKKGLWLGSLLFGIDQKLFGGKVPWTLHNT
CCCHHHHCCCHHHCCCHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCC
ADHTALRPAAECPRIDYPKPDGKLSFDRLSSVFLSNTNHEEEQPCHLQLKDPGVPIAVNL
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEE
AKYDAPEQRYCPAGVYEIVRDGENNAPRLQINAQNCVHCKTCDIKDPTQNINWVVPQGGE
HHCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEECCCC
GPIYQGM
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]