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The map label for this gene is pitA [C]

Identifier: 119898426

GI number: 119898426

Start: 2339196

End: 2340776

Strand: Reverse

Name: pitA [C]

Synonym: azo2135

Alternate gene names: 119898426

Gene position: 2340776-2339196 (Counterclockwise)

Preceding gene: 119898427

Following gene: 119898425

Centisome position: 53.49

GC content: 66.98

Gene sequence:

>1581_bases
TTGGAACTCCAGCACCTTAAGGAAATCGAGAGCGCCACGGCCCACGGGCGCGGCGAGTTGCTGCGTCTGGGGGTCGTCAG
CCTGTTTCTTGTCGCGACGATGCTGTACGCGGCAACGCTGGGCTCCGGCGCCAGCCTGATCCTGGTCGTGGGAGCGGCAT
TGGCGGCCTATATGGCGCTCAACATCGGCGCCAACGACGTGGCAAACAACGTGGGGCCCGCGGTGGGGGCCAGGGCGATG
GGGCTGGTCAGCGCGCTGAGCATCGCCGCGGTGTGCGAGGTGGCGGGGGCGCTGCTGGCAGGCGGTGCCGTCGTCGACAC
CGTGAAGGGCAGCATCCTCCAACGGCACCTGCTGACCGATGGCGACACCGTTGTCGCGGTAATGCTCTGCGCCTTGCTCG
CGGGATCCATCTGGCTGAACGTGGCGACCGCGCTCGGCGCGCCGGTATCGACCACGCACTCCATCGTCGGCGCTGTGCTG
GGTGCAGGCATCGCGGCACGCGGGGTGGAGGTCATCAACTGGGAGACCGTGGTGGCGATCACCACCAGCTGGGTGGCATC
GCCCCTGCTGGGTGCCGGCTTCGCCGCTGCGTTCCTGTACGCGGTGAAGCGCAGCATCACCTATCAGCCCGACATGGCCA
GCGCGGCGCGAAGAGTCGTGCCGTACCTGATGGCCGCGATGACGTGGACCTCCATCGTGTTCCTGCTGGTCAAGGGACTC
AACCGTGCGCTGGTGGTGGAACTGGGGGCCGCCGGCTCGTTCGCCGTGATCCCGGCGACGCTCGTGTTCCTCTACATGCG
GGCCAGGTTGCGGACGCGGGGACATCTGATCGCGAATACCAAGGAAGGCGTGAACAAGCTCTTCAATCCCCCGCTGGTGT
TCGCCGCGGGCTTGCTGAGCTTCGCCCATGGCTCCAACGACGTCGCCAATGCAGTCGGGCCGCTGGCGGCGATCCTCGAT
GCCCTCGGCAGTGCCGGGACGGTCCGCGCGCTCGCGGGGCCGCCGCTGTGGGTGCTGGCGATCGGGGCAATCGGCATCGC
GGTGGGGCTGGCACTGTTCGGGCCTCGCGTCATCCGCACCATCGGCACCGAAATCACCGAACTGGACCAGATGCGGGCGT
TCTGCATCGCGCTGGCGGCCACGGTGACCGTGGTACTGGCGTCCGGGATCGGGCTGCCGGTCAGTTCCACACACATTGTC
GTGGGGGGCGTTTTCGGCGTGGGCTTCCTACGCGAGTTCCTGAAGACGGCCTACGAGCGTACGGTGGCGGAGATCAAGGC
CCACCACCCGGCGGGCGAGCAGCAAGCGCTCGATGCCTTCCTGGAGCGCTTTGGCCAGGCCTCGGTGGCCGAGAAGGACC
GATTGTTGAAGGACCTGAAGGCGCGCTCGAAGAACAGCGAGGACCCCGCCAATTTCTCCAAGTCGGAGCGCAAGAAGCTG
CGCAAGATGTACAAGCAGGAAGTCGTGAAGCGGTCCCAGTTGATGCGGATCGCCGCAGCCTGGGTGGTTACGGTGCCCGT
TTCAGGGGTCTTGGCCGCATTGCTGTACACCTTGCTGGCGCAAGGCGTGGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
TGAGCGCGCACACGGGCGCGCGGAAAAATACGACAAGCTGTGACGGACGCCCGCGGGCCGCTGCTGGCGCCCGCGTCCCG
CTCGAACCGGACTACGCGAA

Downstream 100 bases:

>100_bases
GGAGGCTGGCATGAACGGTTTCGAGGTCGTGGCGCTCGGTCTGCTCGCGGTGGGCGGCTGGTTCTGGTTCGATAGCCTGA
AGGCGAGGGAGGCCGGGATT

Product: putative phosphate permease

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MELQHLKEIESATAHGRGELLRLGVVSLFLVATMLYAATLGSGASLILVVGAALAAYMALNIGANDVANNVGPAVGARAM
GLVSALSIAAVCEVAGALLAGGAVVDTVKGSILQRHLLTDGDTVVAVMLCALLAGSIWLNVATALGAPVSTTHSIVGAVL
GAGIAARGVEVINWETVVAITTSWVASPLLGAGFAAAFLYAVKRSITYQPDMASAARRVVPYLMAAMTWTSIVFLLVKGL
NRALVVELGAAGSFAVIPATLVFLYMRARLRTRGHLIANTKEGVNKLFNPPLVFAAGLLSFAHGSNDVANAVGPLAAILD
ALGSAGTVRALAGPPLWVLAIGAIGIAVGLALFGPRVIRTIGTEITELDQMRAFCIALAATVTVVLASGIGLPVSSTHIV
VGGVFGVGFLREFLKTAYERTVAEIKAHHPAGEQQALDAFLERFGQASVAEKDRLLKDLKARSKNSEDPANFSKSERKKL
RKMYKQEVVKRSQLMRIAAAWVVTVPVSGVLAALLYTLLAQGVARA

Sequences:

>Translated_526_residues
MELQHLKEIESATAHGRGELLRLGVVSLFLVATMLYAATLGSGASLILVVGAALAAYMALNIGANDVANNVGPAVGARAM
GLVSALSIAAVCEVAGALLAGGAVVDTVKGSILQRHLLTDGDTVVAVMLCALLAGSIWLNVATALGAPVSTTHSIVGAVL
GAGIAARGVEVINWETVVAITTSWVASPLLGAGFAAAFLYAVKRSITYQPDMASAARRVVPYLMAAMTWTSIVFLLVKGL
NRALVVELGAAGSFAVIPATLVFLYMRARLRTRGHLIANTKEGVNKLFNPPLVFAAGLLSFAHGSNDVANAVGPLAAILD
ALGSAGTVRALAGPPLWVLAIGAIGIAVGLALFGPRVIRTIGTEITELDQMRAFCIALAATVTVVLASGIGLPVSSTHIV
VGGVFGVGFLREFLKTAYERTVAEIKAHHPAGEQQALDAFLERFGQASVAEKDRLLKDLKARSKNSEDPANFSKSERKKL
RKMYKQEVVKRSQLMRIAAAWVVTVPVSGVLAALLYTLLAQGVARA
>Mature_526_residues
MELQHLKEIESATAHGRGELLRLGVVSLFLVATMLYAATLGSGASLILVVGAALAAYMALNIGANDVANNVGPAVGARAM
GLVSALSIAAVCEVAGALLAGGAVVDTVKGSILQRHLLTDGDTVVAVMLCALLAGSIWLNVATALGAPVSTTHSIVGAVL
GAGIAARGVEVINWETVVAITTSWVASPLLGAGFAAAFLYAVKRSITYQPDMASAARRVVPYLMAAMTWTSIVFLLVKGL
NRALVVELGAAGSFAVIPATLVFLYMRARLRTRGHLIANTKEGVNKLFNPPLVFAAGLLSFAHGSNDVANAVGPLAAILD
ALGSAGTVRALAGPPLWVLAIGAIGIAVGLALFGPRVIRTIGTEITELDQMRAFCIALAATVTVVLASGIGLPVSSTHIV
VGGVFGVGFLREFLKTAYERTVAEIKAHHPAGEQQALDAFLERFGQASVAEKDRLLKDLKARSKNSEDPANFSKSERKKL
RKMYKQEVVKRSQLMRIAAAWVVTVPVSGVLAALLYTLLAQGVARA

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=133, Percent_Identity=45.8646616541353, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI5803173, Length=129, Percent_Identity=47.2868217054264, Blast_Score=107, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17557328, Length=477, Percent_Identity=26.2054507337526, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17539280, Length=169, Percent_Identity=39.0532544378698, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71981576, Length=131, Percent_Identity=43.5114503816794, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566716, Length=250, Percent_Identity=34.4, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25146401, Length=142, Percent_Identity=40.8450704225352, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17536725, Length=193, Percent_Identity=26.9430051813472, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319773, Length=128, Percent_Identity=39.84375, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21356511, Length=194, Percent_Identity=35.0515463917526, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 54592; Mature: 54592

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELQHLKEIESATAHGRGELLRLGVVSLFLVATMLYAATLGSGASLILVVGAALAAYMAL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NIGANDVANNVGPAVGARAMGLVSALSIAAVCEVAGALLAGGAVVDTVKGSILQRHLLTD
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
GDTVVAVMLCALLAGSIWLNVATALGAPVSTTHSIVGAVLGAGIAARGVEVINWETVVAI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHCCCEEECCCCCEEH
TTSWVASPLLGAGFAAAFLYAVKRSITYQPDMASAARRVVPYLMAAMTWTSIVFLLVKGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NRALVVELGAAGSFAVIPATLVFLYMRARLRTRGHLIANTKEGVNKLFNPPLVFAAGLLS
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCCHHHHHHHHHH
FAHGSNDVANAVGPLAAILDALGSAGTVRALAGPPLWVLAIGAIGIAVGLALFGPRVIRT
HHCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGTEITELDQMRAFCIALAATVTVVLASGIGLPVSSTHIVVGGVFGVGFLREFLKTAYER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
TVAEIKAHHPAGEQQALDAFLERFGQASVAEKDRLLKDLKARSKNSEDPANFSKSERKKL
HHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RKMYKQEVVKRSQLMRIAAAWVVTVPVSGVLAALLYTLLAQGVARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELQHLKEIESATAHGRGELLRLGVVSLFLVATMLYAATLGSGASLILVVGAALAAYMAL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NIGANDVANNVGPAVGARAMGLVSALSIAAVCEVAGALLAGGAVVDTVKGSILQRHLLTD
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
GDTVVAVMLCALLAGSIWLNVATALGAPVSTTHSIVGAVLGAGIAARGVEVINWETVVAI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHCCCEEECCCCCEEH
TTSWVASPLLGAGFAAAFLYAVKRSITYQPDMASAARRVVPYLMAAMTWTSIVFLLVKGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NRALVVELGAAGSFAVIPATLVFLYMRARLRTRGHLIANTKEGVNKLFNPPLVFAAGLLS
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHCCCHHHHHHHHHH
FAHGSNDVANAVGPLAAILDALGSAGTVRALAGPPLWVLAIGAIGIAVGLALFGPRVIRT
HHCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGTEITELDQMRAFCIALAATVTVVLASGIGLPVSSTHIVVGGVFGVGFLREFLKTAYER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
TVAEIKAHHPAGEQQALDAFLERFGQASVAEKDRLLKDLKARSKNSEDPANFSKSERKKL
HHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RKMYKQEVVKRSQLMRIAAAWVVTVPVSGVLAALLYTLLAQGVARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]