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The map label for this gene is slyD [H]

Identifier: 119898353

GI number: 119898353

Start: 2262996

End: 2263481

Strand: Reverse

Name: slyD [H]

Synonym: azo2062

Alternate gene names: 119898353

Gene position: 2263481-2262996 (Counterclockwise)

Preceding gene: 119898354

Following gene: 119898352

Centisome position: 51.72

GC content: 60.49

Gene sequence:

>486_bases
ATGCAAACGGAAATCATCAAGAACAGCGTGGTTACGCTTAACTACACCGTCCACGACGCCGACGGCAACATGGTCGACGA
CGGTCACCACCCGCTGACCTACCTCCACGGCGGCTACGACGGCATCTTCCCCGTCATCGAAGAAGCCCTGCATGGCAAGA
AGACCGGTGAAAAGCTGACGATCAAGCTGCAACCGGAAGACGCCTTCGGCGACTACGACGAAGAACTCGTGATGGTGGAA
GACGCTGCGCTGTTCCCGGAGAACATCGAGGTCGGGATGTCCTTCGAGCGCGTGACCGACGACGGCGAGGAAGAGATCAT
CTACCGCATTACCGATATCGCCGAAGGCAAGGTGGTGGTGGACGGCAATCATCCGCTTGCGGGCGTCGCGCTGGTGTTCG
ACCTGACGGTGGCCGACGTTCGCGCGGCGACGGCCGAAGAGATCGGCCATGGTCACGTTCATGGTCCGGGCGGGCATCAC
CACTAA

Upstream 100 bases:

>100_bases
ATCGACAAGCAAGGCGTCGTCCGCCACGTGCTCCGGGACGTCGCACCCCGTGGCCACGCTGCTGCGGTTTATAAACTTGT
CAAGGAATTGGAAACCGACA

Downstream 100 bases:

>100_bases
GCATTCGGGGCCGCGCAAGCGGCCCTTCTTCTTCCAGAACGCCACTTTCAGTCCGCATGGGAACATCGCTGCCCGCCGCT
CAAATCGCTGCCGCGTCAGG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MQTEIIKNSVVTLNYTVHDADGNMVDDGHHPLTYLHGGYDGIFPVIEEALHGKKTGEKLTIKLQPEDAFGDYDEELVMVE
DAALFPENIEVGMSFERVTDDGEEEIIYRITDIAEGKVVVDGNHPLAGVALVFDLTVADVRAATAEEIGHGHVHGPGGHH
H

Sequences:

>Translated_161_residues
MQTEIIKNSVVTLNYTVHDADGNMVDDGHHPLTYLHGGYDGIFPVIEEALHGKKTGEKLTIKLQPEDAFGDYDEELVMVE
DAALFPENIEVGMSFERVTDDGEEEIIYRITDIAEGKVVVDGNHPLAGVALVFDLTVADVRAATAEEIGHGHVHGPGGHH
H
>Mature_161_residues
MQTEIIKNSVVTLNYTVHDADGNMVDDGHHPLTYLHGGYDGIFPVIEEALHGKKTGEKLTIKLQPEDAFGDYDEELVMVE
DAALFPENIEVGMSFERVTDDGEEEIIYRITDIAEGKVVVDGNHPLAGVALVFDLTVADVRAATAEEIGHGHVHGPGGHH
H

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=150, Percent_Identity=38.6666666666667, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17549; Mature: 17549

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTEIIKNSVVTLNYTVHDADGNMVDDGHHPLTYLHGGYDGIFPVIEEALHGKKTGEKLT
CCCCCCCCCEEEEEEEEECCCCCEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEE
IKLQPEDAFGDYDEELVMVEDAALFPENIEVGMSFERVTDDGEEEIIYRITDIAEGKVVV
EEECCCCCCCCCCCEEEEEECCCCCCCCCEECEEEECCCCCCCCEEEEEEEECCCCEEEE
DGNHPLAGVALVFDLTVADVRAATAEEIGHGHVHGPGGHHH
ECCCCCEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTEIIKNSVVTLNYTVHDADGNMVDDGHHPLTYLHGGYDGIFPVIEEALHGKKTGEKLT
CCCCCCCCCEEEEEEEEECCCCCEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEE
IKLQPEDAFGDYDEELVMVEDAALFPENIEVGMSFERVTDDGEEEIIYRITDIAEGKVVV
EEECCCCCCCCCCCEEEEEECCCCCCCCCEECEEEECCCCCCCCEEEEEEEECCCCEEEE
DGNHPLAGVALVFDLTVADVRAATAEEIGHGHVHGPGGHHH
ECCCCCEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]