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The map label for this gene is yoeB [H]

Identifier: 119898315

GI number: 119898315

Start: 2227270

End: 2227524

Strand: Direct

Name: yoeB [H]

Synonym: azo2024

Alternate gene names: 119898315

Gene position: 2227270-2227524 (Clockwise)

Preceding gene: 119898314

Following gene: 119898318

Centisome position: 50.9

GC content: 61.18

Gene sequence:

>255_bases
ATGCCGATTAAGTTCGCCGACCACGCCTGGGAGGACTATCTCTACTGGCAGCAGACCGACAAGGCGATCGTCAAGCGCAT
TAACCAGCTGATCCGGGACATCCAGCGCTCGCCCTTCGAGGGCATCGGCAAACCGGAGCCATTGCGACACCACCTCTCGG
GATACTGGTCCCGGCGCATCAACGACGAGCACCGCCTCGTCTACGCGGTGGAAGATGGCTGCCTCCTGATCGCCGCCTGT
CGCTATCACTACTGA

Upstream 100 bases:

>100_bases
CGCAGCCCGGAAAATGCGCGTCGCCTCGCCGCCTCGATCGAGCAACTGCGCCGGGGCGGCGGCCAGGCCCGGGAACTGGA
TGAAGGCAACGAGACGCCCG

Downstream 100 bases:

>100_bases
GCGTCCAGTACCGGCGCAGCTTTCTCCGCTGTCTTCAAGGGAGCGGGCGGATCGCCTTGCGGGGAATGGGCGCCCTGCGG
TCGAATAGGTGCTCCCCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: Putative endoribonuclease YoeB; Putative mRNA interferase Yoeb [H]

Number of amino acids: Translated: 84; Mature: 83

Protein sequence:

>84_residues
MPIKFADHAWEDYLYWQQTDKAIVKRINQLIRDIQRSPFEGIGKPEPLRHHLSGYWSRRINDEHRLVYAVEDGCLLIAAC
RYHY

Sequences:

>Translated_84_residues
MPIKFADHAWEDYLYWQQTDKAIVKRINQLIRDIQRSPFEGIGKPEPLRHHLSGYWSRRINDEHRLVYAVEDGCLLIAAC
RYHY
>Mature_83_residues
PIKFADHAWEDYLYWQQTDKAIVKRINQLIRDIQRSPFEGIGKPEPLRHHLSGYWSRRINDEHRLVYAVEDGCLLIAACR
YHY

Specific function: Part of a toxin-antitoxin (TA) module. It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation. Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. YefM binds to the pro

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=84, Percent_Identity=69.0476190476191, Blast_Score=134, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10113; Mature: 9981

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKFADHAWEDYLYWQQTDKAIVKRINQLIRDIQRSPFEGIGKPEPLRHHLSGYWSRRI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
NDEHRLVYAVEDGCLLIAACRYHY
CCCCEEEEEECCCEEEEHCCCCCC
>Mature Secondary Structure 
PIKFADHAWEDYLYWQQTDKAIVKRINQLIRDIQRSPFEGIGKPEPLRHHLSGYWSRRI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
NDEHRLVYAVEDGCLLIAACRYHY
CCCCEEEEEECCCEEEEHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]