BacMap

Definition	Azoarcus sp. BH72 chromosome, complete genome.
Accession	NC_008702
Length	4,376,040

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The map label for this gene is fabG [H]

Identifier: 119898280

GI number: 119898280

Start: 2188649

End: 2189377

Strand: Direct

Name: fabG [H]

Synonym: azo1989

Alternate gene names: 119898280

Gene position: 2188649-2189377 (Clockwise)

Preceding gene: 119898279

Following gene: 119898281

Centisome position: 50.01

GC content: 68.31

Gene sequence:

>729_bases
ATGAGCGAACGAATGGTCGCAGTGGTCACCGGCGGCTCCGCCGGCATCGGCGCCGACATCTGCAAGCGCATGCTGGAGGA
TGGCTACGACGTCGTTTCGGTGGCGCGGCGCGCACCGGATTGGACCCATCCGCGCCTCAAGACCGTGCAGGCCGATCTGC
TCGATGCCGCCGCCACCGAACAGGCCGCGCAGGAGATCGCCCGCGAGTTCCCGGTCAGCCATTTCATCCACAACGCCGGC
GTGATCTGGCCCAAGCTGCTCGGCGAGGTCAAGCTCGAAGAGCTGCAGGGCCTCACCCAGATCCACCTCGGCGCGGCGAT
CAGCCTGATGCAGGCCTTCCTGCCTGGCATGACGGAGCGCAATTTCGGCCGCGTCGTGCTGATGTCCTCGCGCGGCGCGC
TCGGCCTGCAGACCCGCACCGCCTACTCCGCCACCAAGGCCGGCATGATCGGCATGGCGCGCACCTGGGCGCTCGAACTC
GCGCCCAAGGGCATCACGGTGAACGTGGTGGCGCCGGGCCCGATCCAGACCGACATGTACTACGCGGTGATCGAACCCGG
CAGCGAGCGCGAGAAGGCGCTGGCCAAGGCGATCCCGGTGCAGCGCGTCGGCCGTGCCGACGACGTCACCCGCGCGCTGA
TGTTCTTCGCCGACCCCGCCAACAGCTTCGTCACCGGGCAGACGCTGTATGTTTGCGGCGGGGCGAGCGTGGGCACGATC
ACGATTTGA

Upstream 100 bases:

>100_bases
CAGGGCGCGCTGATCTTCGCCGCCCCGCTCAAGATCCGTAACGGTTCCGGCAGCCCGCTGCGCGTGCTGGCGCTGACCCC
GAGCGTCTGAGGAGACCACG

Downstream 100 bases:

>100_bases
AGCACCCTCCCGCAGTCACTTTTCTGTTCGCAGCACGACCACACCACCGGAGCAATACCGCCATGAAGCTGAAAAAACTC
CCCGCTGCAGTCGCCCTCGC

Product: short-chain dehydrogenase family protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSERMVAVVTGGSAGIGADICKRMLEDGYDVVSVARRAPDWTHPRLKTVQADLLDAAATEQAAQEIAREFPVSHFIHNAG
VIWPKLLGEVKLEELQGLTQIHLGAAISLMQAFLPGMTERNFGRVVLMSSRGALGLQTRTAYSATKAGMIGMARTWALEL
APKGITVNVVAPGPIQTDMYYAVIEPGSEREKALAKAIPVQRVGRADDVTRALMFFADPANSFVTGQTLYVCGGASVGTI
TI

Sequences:

>Translated_242_residues
MSERMVAVVTGGSAGIGADICKRMLEDGYDVVSVARRAPDWTHPRLKTVQADLLDAAATEQAAQEIAREFPVSHFIHNAG
VIWPKLLGEVKLEELQGLTQIHLGAAISLMQAFLPGMTERNFGRVVLMSSRGALGLQTRTAYSATKAGMIGMARTWALEL
APKGITVNVVAPGPIQTDMYYAVIEPGSEREKALAKAIPVQRVGRADDVTRALMFFADPANSFVTGQTLYVCGGASVGTI
TI
>Mature_241_residues
SERMVAVVTGGSAGIGADICKRMLEDGYDVVSVARRAPDWTHPRLKTVQADLLDAAATEQAAQEIAREFPVSHFIHNAGV
IWPKLLGEVKLEELQGLTQIHLGAAISLMQAFLPGMTERNFGRVVLMSSRGALGLQTRTAYSATKAGMIGMARTWALELA
PKGITVNVVAPGPIQTDMYYAVIEPGSEREKALAKAIPVQRVGRADDVTRALMFFADPANSFVTGQTLYVCGGASVGTIT
I

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=31.1203319502075, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=27.1604938271605, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=25.7936507936508, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=27.9352226720648, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7705925, Length=234, Percent_Identity=29.0598290598291, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI66933014, Length=203, Percent_Identity=25.615763546798, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI223718074, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI59889578, Length=170, Percent_Identity=32.9411764705882, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=33.75, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=26.0869565217391, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=29.4605809128631, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790717, Length=180, Percent_Identity=31.6666666666667, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=26.0330578512397, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082160, Length=238, Percent_Identity=27.7310924369748, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=231, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=25.6198347107438, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=26.2096774193548, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789378, Length=99, Percent_Identity=35.3535353535354, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30.8, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=28.5123966942149, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=25.0965250965251, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=27.6422764227642, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=26.5917602996255, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.1746031746032, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=26.5917602996255, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=23.6434108527132, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=25.5639097744361, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=26.2548262548263, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=91, Percent_Identity=41.7582417582418, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=238, Percent_Identity=29.8319327731092, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=28.6307053941909, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=26.9709543568465, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=29.4354838709677, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=27.9352226720648, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=26.9387755102041, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25856; Mature: 25725

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERMVAVVTGGSAGIGADICKRMLEDGYDVVSVARRAPDWTHPRLKTVQADLLDAAATE
CCCCEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QAAQEIAREFPVSHFIHNAGVIWPKLLGEVKLEELQGLTQIHLGAAISLMQAFLPGMTER
HHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
NFGRVVLMSSRGALGLQTRTAYSATKAGMIGMARTWALELAPKGITVNVVAPGPIQTDMY
CCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHEEEEECCCCEEEEEEECCCCCCCEE
YAVIEPGSEREKALAKAIPVQRVGRADDVTRALMFFADPANSFVTGQTLYVCGGASVGTI
EEEECCCCHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCEECCCEEEEECCCCCCEE
TI
EC
>Mature Secondary Structure 
SERMVAVVTGGSAGIGADICKRMLEDGYDVVSVARRAPDWTHPRLKTVQADLLDAAATE
CCCEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QAAQEIAREFPVSHFIHNAGVIWPKLLGEVKLEELQGLTQIHLGAAISLMQAFLPGMTER
HHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
NFGRVVLMSSRGALGLQTRTAYSATKAGMIGMARTWALELAPKGITVNVVAPGPIQTDMY
CCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHEEEEECCCCEEEEEEECCCCCCCEE
YAVIEPGSEREKALAKAIPVQRVGRADDVTRALMFFADPANSFVTGQTLYVCGGASVGTI
EEEECCCCHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCEECCCEEEEECCCCCCEE
TI
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]