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The map label for this gene is 119898277

Identifier: 119898277

GI number: 119898277

Start: 2185270

End: 2186448

Strand: Direct

Name: 119898277

Synonym: azo1986

Alternate gene names: NA

Gene position: 2185270-2186448 (Clockwise)

Preceding gene: 119898276

Following gene: 119898278

Centisome position: 49.94

GC content: 68.53

Gene sequence:

>1179_bases
GTGAGCACCCGCAAACGGCAAGGCTACGACGGCGTCGTCGCCGTGCTGCCGGTCACCATCCCGTATGCGCGCTACTCCAC
GCGCAGCGCGCACTGGTGGCTGGGCCGCGCGCTCGGCGAACTGGTGCGCGGCAGCGGGCTGGCCAAGGCCCAAATCGACG
GCGTCTGCGTCTCCAGCTTCACGCTCGGCCCGGATACCGCGGTCGGCCTGATGCAGCATCTGGGCATGAGCCCGCGCTGG
CTCGACCACATTCCCATGGGCGGCGCCTCCGGCGTGGTCGCGCTGCGCCGCGCGGCGCGTGCGGTGCAGGCCGGCGACGC
TGAGGTCATCGCCTGCATTGCCGGCGACACCAACGCGGTCGATTCCTTCCGCAATACCGTCAGCCAGTTCTCCCGCTTCG
CGCAGGACGCGGTCTATCCCTACGGCGCCGGCGGCCCCAACGCCAGCTTCGCGCTGCTGACCGATTACTACATGCGGCAC
TACGGCGCCACCCGCGAGGACTTCGGCAAGCTCTGCGTCGCCCAGCGCGACAACGCGCTGAAGAACCCGCACGCGCTGAT
GAAGAAGCCGCTGACGCTGGCGCAGTACATGGAAGCGCGCGCGATCACCGACCCCATCCACCTGTTCGACTGCGTGATGC
CCTGCGCCGGCGCCGAAGGCTATCTGGTGATGACCGAGGACCGCGCCCGCGCGCTGAAGCTGCCCTTCGTGCGCATCCGT
TCCACCATCGAACGCCACAACGCCTTCCCGGAAGACCCGATCCAGTTCCGCGGCGGCTGGGCGATGGACAAGGACGCGCT
CTATGAGCATGCCGGCATCGCGCCCGCCGACGTTGATTTCCTCGAAACCTATGACGATTACCCGGTCATCAACATGATGC
AGTTCGAGGACCTCGGCTTCTGTGCCAAGGGCGAGGCGCCCGCCTTCGTGCGCGAGCACAGCTTCACCATCGAAGGCAGC
TTCCCCTTCAACACCTCGGGCGGCCAGCTTTCGGTGGGCCAGGCCGGCGCCGCCGGCGGCTACCTCGGCTTCGTGCAGGC
GCTGCGCCAGCTCACCGGCGGCGCCGGCCACACCCAGGTGAAGGACGCGAAGATCGGCATGGTGTCCGGCTTCGGCATGA
TCAACTACGACCGCGGCCTGTGTTCCGGCGCCGCCGTCCTCGAACGGGGGCAGGCATGA

Upstream 100 bases:

>100_bases
AGATCCAGCGCGGCGAGCTGAAGGCTCTGGCGCCCACGCTGGTAGACAGCCCCAACTGTGTGAATACCTGCGCGATGAAG
AAGCGCCAGGGAGACCACAA

Downstream 100 bases:

>100_bases
CCGAACCGCTCGCCAAACCGAAAAAGAAGAACCCGGTCCAGCGCACCCGGCTCGCCACCCTGCCGCCGGTGCCGCGCAGC
CGTACCGCGCTCGGCCTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSTRKRQGYDGVVAVLPVTIPYARYSTRSAHWWLGRALGELVRGSGLAKAQIDGVCVSSFTLGPDTAVGLMQHLGMSPRW
LDHIPMGGASGVVALRRAARAVQAGDAEVIACIAGDTNAVDSFRNTVSQFSRFAQDAVYPYGAGGPNASFALLTDYYMRH
YGATREDFGKLCVAQRDNALKNPHALMKKPLTLAQYMEARAITDPIHLFDCVMPCAGAEGYLVMTEDRARALKLPFVRIR
STIERHNAFPEDPIQFRGGWAMDKDALYEHAGIAPADVDFLETYDDYPVINMMQFEDLGFCAKGEAPAFVREHSFTIEGS
FPFNTSGGQLSVGQAGAAGGYLGFVQALRQLTGGAGHTQVKDAKIGMVSGFGMINYDRGLCSGAAVLERGQA

Sequences:

>Translated_392_residues
MSTRKRQGYDGVVAVLPVTIPYARYSTRSAHWWLGRALGELVRGSGLAKAQIDGVCVSSFTLGPDTAVGLMQHLGMSPRW
LDHIPMGGASGVVALRRAARAVQAGDAEVIACIAGDTNAVDSFRNTVSQFSRFAQDAVYPYGAGGPNASFALLTDYYMRH
YGATREDFGKLCVAQRDNALKNPHALMKKPLTLAQYMEARAITDPIHLFDCVMPCAGAEGYLVMTEDRARALKLPFVRIR
STIERHNAFPEDPIQFRGGWAMDKDALYEHAGIAPADVDFLETYDDYPVINMMQFEDLGFCAKGEAPAFVREHSFTIEGS
FPFNTSGGQLSVGQAGAAGGYLGFVQALRQLTGGAGHTQVKDAKIGMVSGFGMINYDRGLCSGAAVLERGQA
>Mature_391_residues
STRKRQGYDGVVAVLPVTIPYARYSTRSAHWWLGRALGELVRGSGLAKAQIDGVCVSSFTLGPDTAVGLMQHLGMSPRWL
DHIPMGGASGVVALRRAARAVQAGDAEVIACIAGDTNAVDSFRNTVSQFSRFAQDAVYPYGAGGPNASFALLTDYYMRHY
GATREDFGKLCVAQRDNALKNPHALMKKPLTLAQYMEARAITDPIHLFDCVMPCAGAEGYLVMTEDRARALKLPFVRIRS
TIERHNAFPEDPIQFRGGWAMDKDALYEHAGIAPADVDFLETYDDYPVINMMQFEDLGFCAKGEAPAFVREHSFTIEGSF
PFNTSGGQLSVGQAGAAGGYLGFVQALRQLTGGAGHTQVKDAKIGMVSGFGMINYDRGLCSGAAVLERGQA

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=361, Percent_Identity=24.6537396121884, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI302344760, Length=322, Percent_Identity=23.9130434782609, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI302344767, Length=303, Percent_Identity=24.4224422442244, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI302344762, Length=228, Percent_Identity=25.4385964912281, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI55956775, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17537653, Length=298, Percent_Identity=24.1610738255034, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921506, Length=321, Percent_Identity=21.183800623053, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24585051, Length=317, Percent_Identity=22.397476340694, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 42311; Mature: 42179

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRKRQGYDGVVAVLPVTIPYARYSTRSAHWWLGRALGELVRGSGLAKAQIDGVCVSSF
CCCCCCCCCCCEEEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEE
TLGPDTAVGLMQHLGMSPRWLDHIPMGGASGVVALRRAARAVQAGDAEVIACIAGDTNAV
ECCCHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
DSFRNTVSQFSRFAQDAVYPYGAGGPNASFALLTDYYMRHYGATREDFGKLCVAQRDNAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
KNPHALMKKPLTLAQYMEARAITDPIHLFDCVMPCAGAEGYLVMTEDRARALKLPFVRIR
CCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCHHHHH
STIERHNAFPEDPIQFRGGWAMDKDALYEHAGIAPADVDFLETYDDYPVINMMQFEDLGF
HHHHHHCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEHHCCCC
CAKGEAPAFVREHSFTIEGSFPFNTSGGQLSVGQAGAAGGYLGFVQALRQLTGGAGHTQV
EECCCCCCEEECCCEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEE
KDAKIGMVSGFGMINYDRGLCSGAAVLERGQA
CCCEEEEEECCCEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
STRKRQGYDGVVAVLPVTIPYARYSTRSAHWWLGRALGELVRGSGLAKAQIDGVCVSSF
CCCCCCCCCCEEEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEE
TLGPDTAVGLMQHLGMSPRWLDHIPMGGASGVVALRRAARAVQAGDAEVIACIAGDTNAV
ECCCHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
DSFRNTVSQFSRFAQDAVYPYGAGGPNASFALLTDYYMRHYGATREDFGKLCVAQRDNAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
KNPHALMKKPLTLAQYMEARAITDPIHLFDCVMPCAGAEGYLVMTEDRARALKLPFVRIR
CCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCHHHHH
STIERHNAFPEDPIQFRGGWAMDKDALYEHAGIAPADVDFLETYDDYPVINMMQFEDLGF
HHHHHHCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEHHCCCC
CAKGEAPAFVREHSFTIEGSFPFNTSGGQLSVGQAGAAGGYLGFVQALRQLTGGAGHTQV
EECCCCCCEEECCCEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEE
KDAKIGMVSGFGMINYDRGLCSGAAVLERGQA
CCCEEEEEECCCEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]