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The map label for this gene is adh [H]

Identifier: 119898262

GI number: 119898262

Start: 2167420

End: 2168526

Strand: Reverse

Name: adh [H]

Synonym: azo1971

Alternate gene names: 119898262

Gene position: 2168526-2167420 (Counterclockwise)

Preceding gene: 119898263

Following gene: 119898261

Centisome position: 49.55

GC content: 69.38

Gene sequence:

>1107_bases
ATGAAAACCATGAAGGCGGCCCGCCTGCACGAGATCGGCGGCAGCTTTGCAATCGACGAAGTCCCGGTGCCTAAACCCGG
CCCGCAGGACGTGCTGGTGCGCGTGGAGGCGTGCGGACTGATCCCCAACCTGCGCAACGTCGTCACCCATTTCCCCACCT
GGTATCCCTTCCTGCCGCTGCCGGCGCTGCCGGCCATCTTCGGGCTGGACGCCGCGGGCACCGTGGCTGCGGTGGGGGAG
GGGGTGAAGTCGGTGCGGCCGGGCGATCGGGTGTACGTCAATCCCGGCCTGTCCTGCGGCGAATGCCGCTACTGCAAGCA
GGGCGAGCCGACGCGCTGCGACGCCTACACCTTCATGGGCTACTTCGGTTTCGGCAAGGGTTCGCAGGCGCTGTTCGAGC
GTTATCCCTACGCCGGCTACGCCGAATACATGACGGCGCCGGTCGCCAACCTGGTCCGCCTGCCGGATCAGGTCAGCAGC
GCGCAGGCGGCCCGCTTCGGCTACATGGGCACCGCCTACTCCGCGCTGCGCAAGGCCGCGCTGCAAGCGGGTCAGAGCGT
GCTGATCCTCGGCGCGACCGGCACCCTGGGTGTCGGCGCGGTGCTGCTGGCGCTGGGATTCGGCGCCGCCCGCGTGGTCG
TCGTGGGGCGCGACCGCGCACTGCTCGACCGCCTGCTGCGGCTCGATCCGAAGCGGGTCGTGCCGCTGCCGCTGGATGGA
CAACCGATCCATCCGCGCGTGCGCGAGCAGGTTCCGGGCGGCGTGGACGCGATGCTCGACACCCTGGGCGCCAAGGCGCC
CGCGGAACTCTCGGTGGATGCGATGCAGGCGGTGGCGCGCGGCGGCCGCATCGTCCAGATCGGCGGCGTTGCGGGGCCGA
TCCCGATCGACCCGCACCCCTTCATGTGCGCGCAGTTGCAGTACATCGGCTCGCTCTGGTTCACCGCTGCCGAGGGCGAC
GAAATGCTGGCGATGATCGAAGCCGGCCTGGTGGACCTGAGCGTGCTGGAACCGCGCCCCTATCCGCTGGAAGCCTTGAA
CGAGGCGCTGGAAGACATCCAGACCCAGGCCAACGGCTTCACCAACTTCCACATCGCCCACCGCTGA

Upstream 100 bases:

>100_bases
GACACCGCGATCACCCTGGCGAAGGCGAGCGCGGCCGCCTGAACGCGACCACACGGCAGGCCGCGCCGTCGGCGCGGCCC
ACATCCAAGGAGAGCGAGAC

Downstream 100 bases:

>100_bases
CATGCAGCGCCGGTCGTTCGCCGCGACCGGCGCCTGCGACAAGGACATCGCCCATGACGCCCCGACGCATCGTGACCGGC
CATGACGAACGTGGCCGCTC

Product: putative alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKTMKAARLHEIGGSFAIDEVPVPKPGPQDVLVRVEACGLIPNLRNVVTHFPTWYPFLPLPALPAIFGLDAAGTVAAVGE
GVKSVRPGDRVYVNPGLSCGECRYCKQGEPTRCDAYTFMGYFGFGKGSQALFERYPYAGYAEYMTAPVANLVRLPDQVSS
AQAARFGYMGTAYSALRKAALQAGQSVLILGATGTLGVGAVLLALGFGAARVVVVGRDRALLDRLLRLDPKRVVPLPLDG
QPIHPRVREQVPGGVDAMLDTLGAKAPAELSVDAMQAVARGGRIVQIGGVAGPIPIDPHPFMCAQLQYIGSLWFTAAEGD
EMLAMIEAGLVDLSVLEPRPYPLEALNEALEDIQTQANGFTNFHIAHR

Sequences:

>Translated_368_residues
MKTMKAARLHEIGGSFAIDEVPVPKPGPQDVLVRVEACGLIPNLRNVVTHFPTWYPFLPLPALPAIFGLDAAGTVAAVGE
GVKSVRPGDRVYVNPGLSCGECRYCKQGEPTRCDAYTFMGYFGFGKGSQALFERYPYAGYAEYMTAPVANLVRLPDQVSS
AQAARFGYMGTAYSALRKAALQAGQSVLILGATGTLGVGAVLLALGFGAARVVVVGRDRALLDRLLRLDPKRVVPLPLDG
QPIHPRVREQVPGGVDAMLDTLGAKAPAELSVDAMQAVARGGRIVQIGGVAGPIPIDPHPFMCAQLQYIGSLWFTAAEGD
EMLAMIEAGLVDLSVLEPRPYPLEALNEALEDIQTQANGFTNFHIAHR
>Mature_368_residues
MKTMKAARLHEIGGSFAIDEVPVPKPGPQDVLVRVEACGLIPNLRNVVTHFPTWYPFLPLPALPAIFGLDAAGTVAAVGE
GVKSVRPGDRVYVNPGLSCGECRYCKQGEPTRCDAYTFMGYFGFGKGSQALFERYPYAGYAEYMTAPVANLVRLPDQVSS
AQAARFGYMGTAYSALRKAALQAGQSVLILGATGTLGVGAVLLALGFGAARVVVVGRDRALLDRLLRLDPKRVVPLPLDG
QPIHPRVREQVPGGVDAMLDTLGAKAPAELSVDAMQAVARGGRIVQIGGVAGPIPIDPHPFMCAQLQYIGSLWFTAAEGD
EMLAMIEAGLVDLSVLEPRPYPLEALNEALEDIQTQANGFTNFHIAHR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=363, Percent_Identity=27.5482093663912, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI13236495, Length=363, Percent_Identity=27.5482093663912, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI34577061, Length=364, Percent_Identity=24.4505494505494, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4501933, Length=369, Percent_Identity=26.0162601626016, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4501929, Length=270, Percent_Identity=27.037037037037, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI156627571, Length=344, Percent_Identity=23.8372093023256, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4501939, Length=373, Percent_Identity=24.3967828418231, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI156523966, Length=373, Percent_Identity=24.3967828418231, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI71565152, Length=370, Percent_Identity=22.972972972973, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI71743840, Length=367, Percent_Identity=20.4359673024523, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI262073058, Length=367, Percent_Identity=20.4359673024523, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI87082125, Length=325, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788073, Length=361, Percent_Identity=26.0387811634349, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790045, Length=370, Percent_Identity=25.1351351351351, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI226510992, Length=335, Percent_Identity=24.1791044776119, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787863, Length=217, Percent_Identity=27.1889400921659, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788075, Length=219, Percent_Identity=31.5068493150685, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788407, Length=209, Percent_Identity=26.7942583732057, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786552, Length=358, Percent_Identity=24.8603351955307, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=343, Percent_Identity=27.9883381924198, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71988145, Length=367, Percent_Identity=25.8855585831063, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562878, Length=215, Percent_Identity=30.2325581395349, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562584, Length=365, Percent_Identity=25.4794520547945, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17565904, Length=250, Percent_Identity=25.2, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562582, Length=355, Percent_Identity=23.3802816901408, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323961, Length=336, Percent_Identity=27.6785714285714, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=212, Percent_Identity=31.6037735849057, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=363, Percent_Identity=23.9669421487603, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=212, Percent_Identity=29.7169811320755, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=330, Percent_Identity=22.7272727272727, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=231, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319258, Length=352, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17137530, Length=263, Percent_Identity=25.4752851711027, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17737897, Length=278, Percent_Identity=27.6978417266187, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737895, Length=379, Percent_Identity=25.3298153034301, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550770, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45551930, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221457811, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39222; Mature: 39222

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMKAARLHEIGGSFAIDEVPVPKPGPQDVLVRVEACGLIPNLRNVVTHFPTWYPFLPL
CCCHHHHHHHHCCCCEEECCCCCCCCCCHHHEEEEHHHCCCCHHHHHHHHCCCCCCCCCC
PALPAIFGLDAAGTVAAVGEGVKSVRPGDRVYVNPGLSCGECRYCKQGEPTRCDAYTFMG
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEH
YFGFGKGSQALFERYPYAGYAEYMTAPVANLVRLPDQVSSAQAARFGYMGTAYSALRKAA
HHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
LQAGQSVLILGATGTLGVGAVLLALGFGAARVVVVGRDRALLDRLLRLDPKRVVPLPLDG
HHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCEEECCCCC
QPIHPRVREQVPGGVDAMLDTLGAKAPAELSVDAMQAVARGGRIVQIGGVAGPIPIDPHP
CCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCC
FMCAQLQYIGSLWFTAAEGDEMLAMIEAGLVDLSVLEPRPYPLEALNEALEDIQTQANGF
HHHHHHHHHHHHHEEECCCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
TNFHIAHR
EEEEEECC
>Mature Secondary Structure
MKTMKAARLHEIGGSFAIDEVPVPKPGPQDVLVRVEACGLIPNLRNVVTHFPTWYPFLPL
CCCHHHHHHHHCCCCEEECCCCCCCCCCHHHEEEEHHHCCCCHHHHHHHHCCCCCCCCCC
PALPAIFGLDAAGTVAAVGEGVKSVRPGDRVYVNPGLSCGECRYCKQGEPTRCDAYTFMG
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEH
YFGFGKGSQALFERYPYAGYAEYMTAPVANLVRLPDQVSSAQAARFGYMGTAYSALRKAA
HHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
LQAGQSVLILGATGTLGVGAVLLALGFGAARVVVVGRDRALLDRLLRLDPKRVVPLPLDG
HHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCEEECCCCC
QPIHPRVREQVPGGVDAMLDTLGAKAPAELSVDAMQAVARGGRIVQIGGVAGPIPIDPHP
CCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCC
FMCAQLQYIGSLWFTAAEGDEMLAMIEAGLVDLSVLEPRPYPLEALNEALEDIQTQANGF
HHHHHHHHHHHHHEEECCCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
TNFHIAHR
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA