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The map label for this gene is amiD [H]

Identifier: 119898247

GI number: 119898247

Start: 2151974

End: 2153371

Strand: Reverse

Name: amiD [H]

Synonym: azo1956

Alternate gene names: 119898247

Gene position: 2153371-2151974 (Counterclockwise)

Preceding gene: 119898248

Following gene: 119898246

Centisome position: 49.21

GC content: 74.89

Gene sequence:

>1398_bases
ATGAGCCGCACGGCCCCCGAACTGCATTACCTGGAGATCGCCGAACTCGCGCCGCTGCTGCGCGCCGGCGACATCTCGCC
GCTGGCGCTGACGCGCCACATGCTGGCGCGCATCGACGCGCTCGACAGCCGCCTGCACGCGTATGCCCGCGTCACCGCGG
ACGAGGCCTTGGCCGCCGCCGCGCAAGCCGAGGCGGACATCGCGGCCGGCCGCTACCGCGGACCGCTGCATGGCGTGCCT
GTCGCCGTGAAGGACCTGTTCTGGACGCGCGGCACCGTTACTGCCTGCGGCACCACGGTGCTCGCCGACTTCGTGCCCGA
TGAGGACGCCACCGTGGTGCGGCGCCTGCGCGAGGCGGGTGCGGTCATCCTCGGCAAGCTGCAGATGACCGAGGGCGCCT
TCGCCACCCCGCATCCCGACCTCGCCGCGCCGCTCAACCCCTGGGGCGCGGACCACTGGACCGGCGCCTCCTCCAGCGGC
TCCGGCGTCGCCACCGCCGCCGGCCTGTGCTTTGCCGCGCTCGGCACCGACACCGGCGGCTCGATCCGCTTTCCGGCCGC
GGCCAATGGGCTCTCCGGGCTGAAACCGGGGTGGGGCAGGGTGAGCCGGCACGGCGTGTTTCCGCTGGCGCCCACGCTGG
ACCACGTGGGCCCGATGGCGCGCAGCGTGCGCGACGTGGCGCTGATGTATCAGGCGATCGCCGGCCCCGATCCGCTCGAC
CCGACCTCGCTCGACGACGCGCCGCGGGCTGCTGGCCATAGCGGCCTGGCCGGCTTGCGGGTCGGCATCGACGCCGCCTG
GAACGCGCGCGGCTCCGACGCCGAGGTGCTTGCCGGCTGCGCCCGCCTGCGTGAAGCCCTGGTGGCGGGCGGTGCCGAGA
TCGTGGAACTCGAGCTGCCGGAGTCCTGGCCGATCGCCGGCGCCTGGGAGCTGTTGTGCGGCGTGCAGACGGCGGTGGCG
CACGCGGCCACCTATCCCGCCCGCGCGGCGGACTACGGCCCCGCGCTGGCGCGGCTGATCGAGGTCGGGCGCGCTGCCGG
CGCGATGGACTATCACCGCGCCCAGCTCGCCGCGCTGGATTTTGGCGGACGGCTGGAGCGCGCCCTGGCCGGTGTCGATC
TGCTGCTCGCGCCGGTCCAGCCCTTTGCGGCGCCCACGCACGCGCGGCTCGGCGAACTGGCGCAGAGCCCGGAACTGAAC
CAGCGCCTGATCCAGTTCACCGCGCCGCTCAACATCAGCGGCTCGCCGTCCCTCGCGCTGCCCTGCGGCAGCACCGCCGC
CGGCCTGCCAGTGGGCTGCCAGCTGATCGCGCGCAAGGGCGGCGAAGCCACGCTGCTCGCGGCCGGCGCCGCGCTGCAGG
CCGTCACCCACTGGCACCGCGCGCACCCGCCGCTGTGA

Upstream 100 bases:

>100_bases
CCCGGCTGCATGTCGTCGGCAATGCCGCGCATCACCTGCAGACCGAGCGGCCGGACGAGTTCAACGCCGCCGCGCTCGCC
TTTCTCGGCGGGTACGCCGC

Downstream 100 bases:

>100_bases
GCCGCCCCGATCCCGCACACACAAGCCCCACAGGAGAAACCGCATGACCTCGCCCCGCACCACCGAGGGCCCCGGCCTCG
CCGCCGGGCCCACGCTTGCC

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSRTAPELHYLEIAELAPLLRAGDISPLALTRHMLARIDALDSRLHAYARVTADEALAAAAQAEADIAAGRYRGPLHGVP
VAVKDLFWTRGTVTACGTTVLADFVPDEDATVVRRLREAGAVILGKLQMTEGAFATPHPDLAAPLNPWGADHWTGASSSG
SGVATAAGLCFAALGTDTGGSIRFPAAANGLSGLKPGWGRVSRHGVFPLAPTLDHVGPMARSVRDVALMYQAIAGPDPLD
PTSLDDAPRAAGHSGLAGLRVGIDAAWNARGSDAEVLAGCARLREALVAGGAEIVELELPESWPIAGAWELLCGVQTAVA
HAATYPARAADYGPALARLIEVGRAAGAMDYHRAQLAALDFGGRLERALAGVDLLLAPVQPFAAPTHARLGELAQSPELN
QRLIQFTAPLNISGSPSLALPCGSTAAGLPVGCQLIARKGGEATLLAAGAALQAVTHWHRAHPPL

Sequences:

>Translated_465_residues
MSRTAPELHYLEIAELAPLLRAGDISPLALTRHMLARIDALDSRLHAYARVTADEALAAAAQAEADIAAGRYRGPLHGVP
VAVKDLFWTRGTVTACGTTVLADFVPDEDATVVRRLREAGAVILGKLQMTEGAFATPHPDLAAPLNPWGADHWTGASSSG
SGVATAAGLCFAALGTDTGGSIRFPAAANGLSGLKPGWGRVSRHGVFPLAPTLDHVGPMARSVRDVALMYQAIAGPDPLD
PTSLDDAPRAAGHSGLAGLRVGIDAAWNARGSDAEVLAGCARLREALVAGGAEIVELELPESWPIAGAWELLCGVQTAVA
HAATYPARAADYGPALARLIEVGRAAGAMDYHRAQLAALDFGGRLERALAGVDLLLAPVQPFAAPTHARLGELAQSPELN
QRLIQFTAPLNISGSPSLALPCGSTAAGLPVGCQLIARKGGEATLLAAGAALQAVTHWHRAHPPL
>Mature_464_residues
SRTAPELHYLEIAELAPLLRAGDISPLALTRHMLARIDALDSRLHAYARVTADEALAAAAQAEADIAAGRYRGPLHGVPV
AVKDLFWTRGTVTACGTTVLADFVPDEDATVVRRLREAGAVILGKLQMTEGAFATPHPDLAAPLNPWGADHWTGASSSGS
GVATAAGLCFAALGTDTGGSIRFPAAANGLSGLKPGWGRVSRHGVFPLAPTLDHVGPMARSVRDVALMYQAIAGPDPLDP
TSLDDAPRAAGHSGLAGLRVGIDAAWNARGSDAEVLAGCARLREALVAGGAEIVELELPESWPIAGAWELLCGVQTAVAH
AATYPARAADYGPALARLIEVGRAAGAMDYHRAQLAALDFGGRLERALAGVDLLLAPVQPFAAPTHARLGELAQSPELNQ
RLIQFTAPLNISGSPSLALPCGSTAAGLPVGCQLIARKGGEATLLAAGAALQAVTHWHRAHPPL

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=501, Percent_Identity=29.7405189620758, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI195972892, Length=485, Percent_Identity=24.3298969072165, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI166795287, Length=253, Percent_Identity=32.4110671936759, Blast_Score=76, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17543272, Length=403, Percent_Identity=32.0099255583127, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17537465, Length=475, Percent_Identity=25.2631578947368, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17538252, Length=205, Percent_Identity=27.8048780487805, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17556264, Length=228, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319685, Length=389, Percent_Identity=30.8483290488432, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323950, Length=420, Percent_Identity=27.3809523809524, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320448, Length=243, Percent_Identity=28.3950617283951, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24648113, Length=493, Percent_Identity=33.2657200811359, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24644968, Length=496, Percent_Identity=24.7983870967742, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI161078093, Length=467, Percent_Identity=25.2676659528908, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24652985, Length=485, Percent_Identity=23.9175257731959, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19922090, Length=485, Percent_Identity=23.9175257731959, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24652981, Length=485, Percent_Identity=23.9175257731959, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24652983, Length=485, Percent_Identity=23.9175257731959, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356731, Length=471, Percent_Identity=23.5668789808917, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648435, Length=256, Percent_Identity=27.734375, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648437, Length=256, Percent_Identity=27.734375, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550774, Length=256, Percent_Identity=27.734375, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 47932; Mature: 47801

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTAPELHYLEIAELAPLLRAGDISPLALTRHMLARIDALDSRLHAYARVTADEALAAA
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAEADIAAGRYRGPLHGVPVAVKDLFWTRGTVTACGTTVLADFVPDEDATVVRRLREAG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCC
AVILGKLQMTEGAFATPHPDLAAPLNPWGADHWTGASSSGSGVATAAGLCFAALGTDTGG
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
SIRFPAAANGLSGLKPGWGRVSRHGVFPLAPTLDHVGPMARSVRDVALMYQAIAGPDPLD
CEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PTSLDDAPRAAGHSGLAGLRVGIDAAWNARGSDAEVLAGCARLREALVAGGAEIVELELP
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
ESWPIAGAWELLCGVQTAVAHAATYPARAADYGPALARLIEVGRAAGAMDYHRAQLAALD
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
FGGRLERALAGVDLLLAPVQPFAAPTHARLGELAQSPELNQRLIQFTAPLNISGSPSLAL
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEE
PCGSTAAGLPVGCQLIARKGGEATLLAAGAALQAVTHWHRAHPPL
CCCCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRTAPELHYLEIAELAPLLRAGDISPLALTRHMLARIDALDSRLHAYARVTADEALAAA
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAEADIAAGRYRGPLHGVPVAVKDLFWTRGTVTACGTTVLADFVPDEDATVVRRLREAG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCC
AVILGKLQMTEGAFATPHPDLAAPLNPWGADHWTGASSSGSGVATAAGLCFAALGTDTGG
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
SIRFPAAANGLSGLKPGWGRVSRHGVFPLAPTLDHVGPMARSVRDVALMYQAIAGPDPLD
CEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PTSLDDAPRAAGHSGLAGLRVGIDAAWNARGSDAEVLAGCARLREALVAGGAEIVELELP
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
ESWPIAGAWELLCGVQTAVAHAATYPARAADYGPALARLIEVGRAAGAMDYHRAQLAALD
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
FGGRLERALAGVDLLLAPVQPFAAPTHARLGELAQSPELNQRLIQFTAPLNISGSPSLAL
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEE
PCGSTAAGLPVGCQLIARKGGEATLLAAGAALQAVTHWHRAHPPL
CCCCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]