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The map label for this gene is abmD [H]

Identifier: 119898222

GI number: 119898222

Start: 2118989

End: 2120140

Strand: Reverse

Name: abmD [H]

Synonym: azo1931

Alternate gene names: 119898222

Gene position: 2120140-2118989 (Counterclockwise)

Preceding gene: 119898223

Following gene: 119898221

Centisome position: 48.45

GC content: 69.1

Gene sequence:

>1152_bases
ATGGACCGCTCCATCCTCGACCTGCCGTTCTACGGCCCCGAACACCGCCAGCTGTCGGACGCGATCTTCGACTGGGCATC
CACCGCGATGCCCCACGTCGATCACCACGACACCGACAATGCCTGCCGCCAGCTCGTCGCCGCGCTCGGCAAGGCCGGTT
TCCTGCGCTACGCGGTGCCGGCCGCCTACGGCGGCGCGCTCGCCGAACTCGATTCGCGCTCGCTCTGCATTGCCCGCGAA
ACGCTCGCCTACCACGACGGCCTCGCCGACTTCGCCTTCGCCATGCAGGGCCTGGGCACCGGCGCGATCACCCTGTCCGG
CAGCGAAGAGATCAAGCGCCACGTGCTGCCCAAGGTGGCCGCCGGCGAATGGATTTCCGCCTTCGCGCTGACCGAACCGC
TGGCCGGCTCCGACGTCGGCGCGATGAGCTGCGAAGCGCGCCTTGAAGGCGACCACTACGTCATCAACGGCGAAAAGACC
TGGATCTCCAACGGCGGCATCGCCGATGTGTACTGCCTCTTCGCCCGCACCGGCGAGGCGCCCGGCACGCGCGGCATCTC
CGCCTTCGTGGTCTATCCCGACATGCCCGGCTTCGAAGTCGCCGAGCGCCTGGATACGATCGCGCCGCATCCGCTCGCCC
GCCTGCGCTTCACCGACATGAAGGTGCCCGTGGCCAACCGCCTCGGCGCGCCGGGCGAAGGCTTCAAGGTGGCGATGCGC
ACGCTCGACATCTTCCGCGCCTCGGTCGCCGCCGCCGCGCTCGGCTTTGCCCGCCGCGCGCTCGACGAAGCCCTGAACCA
CGCCCGCCAGCGCCCGATGTTCGGCCACACGCTCGCCGACTTCCAGCTGACGCAGGCCAAGCTCGGCGACATGGCCACCG
ACATCGAAGCCGCCGCGCTGCTCACCGCGCGAGCCGCCTGGCGCCGCGACGTGCAGAAGCTGCCGACCACCCGCGAAGCC
GCGATGGCCAAGATGACCGCCACCGAGAATGCCCAGCGCGTGATCGACGCCGCGGTGCAAATCCACGGCGGGCAGGGCGT
GCGCATCGGCGTCATGGTCGAATCGCTCTACCGCGAAATCCGCGCGCTGCGCATCTATGAAGGCGCGACAGAAGTGCAGA
AGCTGATCGTCGCCCGCGAACTGTTGAAGTAA

Upstream 100 bases:

>100_bases
CAGGCCCAGGCCATCTGCATGATGACCGGCGACTTCCGCCGCGCCTTCGAAGCCTTCGCCGCCAAGCAGAAACCCAAGTT
CGAAGGAAACTGAGCACGCC

Downstream 100 bases:

>100_bases
GCCTACCCCCAGCCCCGACCCCAACCCCTACGGAGCCGAACAGAGCATGAGCAAAGTCCAATTCAACTGGGAAGACCCCC
TCCACCTCGACAGCCAGCTG

Product: putative acyl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDRSILDLPFYGPEHRQLSDAIFDWASTAMPHVDHHDTDNACRQLVAALGKAGFLRYAVPAAYGGALAELDSRSLCIARE
TLAYHDGLADFAFAMQGLGTGAITLSGSEEIKRHVLPKVAAGEWISAFALTEPLAGSDVGAMSCEARLEGDHYVINGEKT
WISNGGIADVYCLFARTGEAPGTRGISAFVVYPDMPGFEVAERLDTIAPHPLARLRFTDMKVPVANRLGAPGEGFKVAMR
TLDIFRASVAAAALGFARRALDEALNHARQRPMFGHTLADFQLTQAKLGDMATDIEAAALLTARAAWRRDVQKLPTTREA
AMAKMTATENAQRVIDAAVQIHGGQGVRIGVMVESLYREIRALRIYEGATEVQKLIVARELLK

Sequences:

>Translated_383_residues
MDRSILDLPFYGPEHRQLSDAIFDWASTAMPHVDHHDTDNACRQLVAALGKAGFLRYAVPAAYGGALAELDSRSLCIARE
TLAYHDGLADFAFAMQGLGTGAITLSGSEEIKRHVLPKVAAGEWISAFALTEPLAGSDVGAMSCEARLEGDHYVINGEKT
WISNGGIADVYCLFARTGEAPGTRGISAFVVYPDMPGFEVAERLDTIAPHPLARLRFTDMKVPVANRLGAPGEGFKVAMR
TLDIFRASVAAAALGFARRALDEALNHARQRPMFGHTLADFQLTQAKLGDMATDIEAAALLTARAAWRRDVQKLPTTREA
AMAKMTATENAQRVIDAAVQIHGGQGVRIGVMVESLYREIRALRIYEGATEVQKLIVARELLK
>Mature_383_residues
MDRSILDLPFYGPEHRQLSDAIFDWASTAMPHVDHHDTDNACRQLVAALGKAGFLRYAVPAAYGGALAELDSRSLCIARE
TLAYHDGLADFAFAMQGLGTGAITLSGSEEIKRHVLPKVAAGEWISAFALTEPLAGSDVGAMSCEARLEGDHYVINGEKT
WISNGGIADVYCLFARTGEAPGTRGISAFVVYPDMPGFEVAERLDTIAPHPLARLRFTDMKVPVANRLGAPGEGFKVAMR
TLDIFRASVAAAALGFARRALDEALNHARQRPMFGHTLADFQLTQAKLGDMATDIEAAALLTARAAWRRDVQKLPTTREA
AMAKMTATENAQRVIDAAVQIHGGQGVRIGVMVESLYREIRALRIYEGATEVQKLIVARELLK

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=343, Percent_Identity=41.9825072886297, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI187960098, Length=334, Percent_Identity=37.125748502994, Blast_Score=198, Evalue=5e-51,
Organism=Homo sapiens, GI4557231, Length=334, Percent_Identity=37.125748502994, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=31.6489361702128, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=30.5263157894737, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=33.5311572700297, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI21361497, Length=362, Percent_Identity=33.1491712707182, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI4501859, Length=355, Percent_Identity=33.8028169014084, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI76496475, Length=326, Percent_Identity=34.9693251533742, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4557235, Length=326, Percent_Identity=34.9693251533742, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=30.9711286089239, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI48976061, Length=332, Percent_Identity=31.3253012048193, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI211971008, Length=332, Percent_Identity=31.3253012048193, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI38505218, Length=297, Percent_Identity=28.956228956229, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4503943, Length=356, Percent_Identity=27.5280898876405, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7669494, Length=344, Percent_Identity=27.3255813953488, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786223, Length=345, Percent_Identity=27.536231884058, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081958, Length=345, Percent_Identity=27.536231884058, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082384, Length=289, Percent_Identity=27.681660899654, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081702, Length=339, Percent_Identity=23.8938053097345, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17534899, Length=339, Percent_Identity=37.1681415929204, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17570075, Length=335, Percent_Identity=35.5223880597015, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17569725, Length=337, Percent_Identity=35.9050445103858, Blast_Score=200, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI17533517, Length=279, Percent_Identity=36.5591397849462, Blast_Score=190, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=354, Percent_Identity=34.4632768361582, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17538396, Length=362, Percent_Identity=33.9779005524862, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17508101, Length=353, Percent_Identity=33.4277620396601, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=31.8181818181818, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=33.4532374100719, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=301, Percent_Identity=32.890365448505, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17551932, Length=335, Percent_Identity=30.1492537313433, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17505929, Length=339, Percent_Identity=29.7935103244838, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71982178, Length=282, Percent_Identity=28.3687943262411, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=30.7017543859649, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17534353, Length=339, Percent_Identity=29.2035398230088, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=29.1666666666667, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=334, Percent_Identity=28.7425149700599, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=277, Percent_Identity=27.0758122743682, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=277, Percent_Identity=27.0758122743682, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24646207, Length=386, Percent_Identity=37.3056994818653, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21356377, Length=390, Percent_Identity=36.4102564102564, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24660351, Length=336, Percent_Identity=36.6071428571429, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI281363737, Length=380, Percent_Identity=33.1578947368421, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24666513, Length=341, Percent_Identity=34.6041055718475, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21355753, Length=356, Percent_Identity=32.5842696629214, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI19920834, Length=293, Percent_Identity=30.3754266211604, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 41461; Mature: 41461

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRSILDLPFYGPEHRQLSDAIFDWASTAMPHVDHHDTDNACRQLVAALGKAGFLRYAVP
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
AAYGGALAELDSRSLCIARETLAYHDGLADFAFAMQGLGTGAITLSGSEEIKRHVLPKVA
HHHCCHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCHH
AGEWISAFALTEPLAGSDVGAMSCEARLEGDHYVINGEKTWISNGGIADVYCLFARTGEA
HCHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCEEEECCCCHHHHHHEEHHCCCC
PGTRGISAFVVYPDMPGFEVAERLDTIAPHPLARLRFTDMKVPVANRLGAPGEGFKVAMR
CCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHEEEECCCCCHHHHCCCCCCCHHHHHH
TLDIFRASVAAAALGFARRALDEALNHARQRPMFGHTLADFQLTQAKLGDMATDIEAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTARAAWRRDVQKLPTTREAAMAKMTATENAQRVIDAAVQIHGGQGVRIGVMVESLYREI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHH
RALRIYEGATEVQKLIVARELLK
HHHHHHCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDRSILDLPFYGPEHRQLSDAIFDWASTAMPHVDHHDTDNACRQLVAALGKAGFLRYAVP
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
AAYGGALAELDSRSLCIARETLAYHDGLADFAFAMQGLGTGAITLSGSEEIKRHVLPKVA
HHHCCHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCHH
AGEWISAFALTEPLAGSDVGAMSCEARLEGDHYVINGEKTWISNGGIADVYCLFARTGEA
HCHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCEEEECCCCHHHHHHEEHHCCCC
PGTRGISAFVVYPDMPGFEVAERLDTIAPHPLARLRFTDMKVPVANRLGAPGEGFKVAMR
CCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHEEEECCCCCHHHHCCCCCCCHHHHHH
TLDIFRASVAAAALGFARRALDEALNHARQRPMFGHTLADFQLTQAKLGDMATDIEAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LTARAAWRRDVQKLPTTREAAMAKMTATENAQRVIDAAVQIHGGQGVRIGVMVESLYREI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHH
RALRIYEGATEVQKLIVARELLK
HHHHHHCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]