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The map label for this gene is etfA2 [H]

Identifier: 119898212

GI number: 119898212

Start: 2109292

End: 2110215

Strand: Reverse

Name: etfA2 [H]

Synonym: azo1921

Alternate gene names: 119898212

Gene position: 2110215-2109292 (Counterclockwise)

Preceding gene: 119898213

Following gene: 119898211

Centisome position: 48.22

GC content: 69.16

Gene sequence:

>924_bases
ATGATTCTTGTCCTTGCCGAACACGACAACCACACCCTCAAGGCCGCCACCCTCAACACGGTGACGGCCGCCGCCAAGAT
CGGCGGTGACATTCATGTTCTCGTCGCGGGCAGCAACTGCGGCGCCGCCGCCGAAGCCGCGGCCAAGGTGGCCGGCGTCG
CCAAGGTGCTGGTGGCCGATGCCCCGCATCTGGACGCCCAGCTCGCCGAGAACGTGAGCGTGCTGCTGCAGACGCTCGCG
CCGGCCTACAGCCACGTGCTCGCGCCGTCGACTTCCGCCGGCAAGAACACGCTGCCGCGCGTGGCCGCGCTGCTCGACGT
CGCGCAGATCAGCGACATCGTCGGTGTGGAGGCCGCCGACACCTTCGTGCGCCCGATCTACGCCGGCAACGCGCTGGCCA
CCGTCAAGAGCGCCGACGCGGTCAAGGTCATCACCGTGCGCACCACCGCGTTCGAAGCAGCAGGCGAGGGCGGTAGTGCC
GCGATCGAAGCAGTCGCCACCGGCGCGGATGCCGGCCAGTCCAACCTCGTCGGGCGCGAGATCACCAAGAGCGCACGCCC
CGAACTCGGTGCCGCCAAGATCATCGTCTCGGGCGGTCGCGGCCTGGGCAGCGGCGAGAACTACACCACGCTGCTCGAAC
CGCTCGCCGACAAGCTGGGCGCGGCGCTCGGCGCGAGCCGCGCGGCGGTCGATGCCGGCTACGTGCCCAATGACTACCAG
GTCGGCCAGACCGGCAAGATCGTCGCGCCGCAGCTCTACATCGCGGTCGGCATCTCGGGTGCCATCCAGCACCTGGCCGG
CATGAAGGACTCCAAGGTGATCGTGGCGATCAACAAGGACCCCGAAGCGCCGATCTTCCAGGTGGCCGACTACGGTCTGG
TGGGTGACCTGTTCGAGGTGGTGCCGGCGCTGACCGCGGCCTGA

Upstream 100 bases:

>100_bases
GGTGCTCTGAGATGACTACCCCCACACTTGCGGCTTACGCCGCTACGCTGCCCCCCAAGGGGGCGTGCATCCTCCTTGGG
ACGGCCCGGCGGAGGATGCA

Downstream 100 bases:

>100_bases
ACGTTTTTCCGCTCCCGACGGGTGCAGCTTCTACTCCCTCTCTCCGCACCTGTCGGTTTCTTCGCCGTCCCGGTTTGCCC
GGGGCGGCGTCTTTTCCGGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVADAPHLDAQLAENVSVLLQTLA
PAYSHVLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSA
AIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDYQ
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAA

Sequences:

>Translated_307_residues
MILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVADAPHLDAQLAENVSVLLQTLA
PAYSHVLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSA
AIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDYQ
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAA
>Mature_307_residues
MILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVADAPHLDAQLAENVSVLLQTLA
PAYSHVLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSA
AIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDYQ
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=60.4575163398693, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI189181759, Length=267, Percent_Identity=61.7977528089888, Blast_Score=306, Evalue=1e-83,
Organism=Escherichia coli, GI1786226, Length=238, Percent_Identity=38.2352941176471, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787990, Length=253, Percent_Identity=33.596837944664, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082157, Length=230, Percent_Identity=32.1739130434783, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=309, Percent_Identity=58.5760517799353, Blast_Score=334, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6325261, Length=289, Percent_Identity=45.6747404844291, Blast_Score=249, Evalue=3e-67,
Organism=Drosophila melanogaster, GI17136898, Length=307, Percent_Identity=64.1693811074919, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652801, Length=307, Percent_Identity=64.1693811074919, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 30738; Mature: 30738

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVAD
CEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
APHLDAQLAENVSVLLQTLAPAYSHVLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAAD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
TFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSAAIEAVATGADAGQSNLVGRE
HHHHHHCCCCEEEEEECCCCEEEEEEEEEEHHCCCCCCCHHHHHHHCCCCCCCCCCCHHH
ITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDYQ
HHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCE
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEV
ECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHH
VPALTAA
HHHHHCC
>Mature Secondary Structure
MILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVAD
CEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
APHLDAQLAENVSVLLQTLAPAYSHVLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAAD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
TFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSAAIEAVATGADAGQSNLVGRE
HHHHHHCCCCEEEEEECCCCEEEEEEEEEEHHCCCCCCCHHHHHHHCCCCCCCCCCCHHH
ITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDYQ
HHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCE
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEV
ECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHH
VPALTAA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]