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The map label for this gene is rmlC [H]

Identifier: 119898165

GI number: 119898165

Start: 2056922

End: 2057467

Strand: Reverse

Name: rmlC [H]

Synonym: azo1874

Alternate gene names: 119898165

Gene position: 2057467-2056922 (Counterclockwise)

Preceding gene: 119898166

Following gene: 119898152

Centisome position: 47.02

GC content: 59.16

Gene sequence:

>546_bases
ATGCGCGTGATTCCCACCGCGATTCCCGAGGTGCTGATGCTTGAACCTCAAGTGTTTGGCGACAGCCGCGGTTTCTTCCT
GGAGAGTTTCAACGCGAACCGGTTCGAGACTGCCACCGGCCTGCCCCCTGTGTTTGTTCAGGACAACCATTCCAGATCAA
GCCGCGGCGTTCTACGCGGCCTCCACTACCAGCTCAGTCAGCCGCAAGGAAAACTGGTTCGCGTCGCACGAGGCAGGGTA
TTCGACGTGGCGGTCGACCTGAGGCGAAGTTCGGCCACATTCGCGCAGTGGGTCGGTACCGAGTTGAGTGACGAGAATCA
GCGTCAAATGTGGATTCCACCCGGTTTCGCACACGGATTCGTCGTGCTGAGCGATACCGCGGACTTTCTCTACAAGACCA
CCGATTACTATGCCCCGGAAGCAGAACGTTGCGTCCTGTGGAACGACCCTGCGCTGGGCATCGAGTGGCCGATCTCGGAA
CCGCCGCTGCTGTCAGCGAAGGATCAATCGGGCAAGCTTCTGGCCGAAGCAGAGTGTTTTCCCTGA

Upstream 100 bases:

>100_bases
GCTGGATCGACTCGGCGGCACTGGAAGCACTGGCAGCGCCGCTGGCCAAGAACGGCTACGGCCAATACCTGAAACGTTTG
CTCGAAGACAAGGTGTTCTG

Downstream 100 bases:

>100_bases
TCAGGAAGCCGCCAGTAGCGGCGAGCATGCGCTCGCAGCCGCCGCTACCTGCAATTCCGGCACGAGAGATAGACGCGCCG
TGGCGAAGGCGCAATGAAGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MRVIPTAIPEVLMLEPQVFGDSRGFFLESFNANRFETATGLPPVFVQDNHSRSSRGVLRGLHYQLSQPQGKLVRVARGRV
FDVAVDLRRSSATFAQWVGTELSDENQRQMWIPPGFAHGFVVLSDTADFLYKTTDYYAPEAERCVLWNDPALGIEWPISE
PPLLSAKDQSGKLLAEAECFP

Sequences:

>Translated_181_residues
MRVIPTAIPEVLMLEPQVFGDSRGFFLESFNANRFETATGLPPVFVQDNHSRSSRGVLRGLHYQLSQPQGKLVRVARGRV
FDVAVDLRRSSATFAQWVGTELSDENQRQMWIPPGFAHGFVVLSDTADFLYKTTDYYAPEAERCVLWNDPALGIEWPISE
PPLLSAKDQSGKLLAEAECFP
>Mature_181_residues
MRVIPTAIPEVLMLEPQVFGDSRGFFLESFNANRFETATGLPPVFVQDNHSRSSRGVLRGLHYQLSQPQGKLVRVARGRV
FDVAVDLRRSSATFAQWVGTELSDENQRQMWIPPGFAHGFVVLSDTADFLYKTTDYYAPEAERCVLWNDPALGIEWPISE
PPLLSAKDQSGKLLAEAECFP

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=170, Percent_Identity=58.2352941176471, Blast_Score=207, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17550412, Length=160, Percent_Identity=44.375, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20301; Mature: 20301

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIPTAIPEVLMLEPQVFGDSRGFFLESFNANRFETATGLPPVFVQDNHSRSSRGVLRG
CCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCEECCCCCCEEEEECCCCCCHHHHHHH
LHYQLSQPQGKLVRVARGRVFDVAVDLRRSSATFAQWVGTELSDENQRQMWIPPGFAHGF
HHHCCCCCCCEEEEEECCEEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCE
VVLSDTADFLYKTTDYYAPEAERCVLWNDPALGIEWPISEPPLLSAKDQSGKLLAEAECF
EEEECCCCCEEECCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCEEEECCCC
P
C
>Mature Secondary Structure
MRVIPTAIPEVLMLEPQVFGDSRGFFLESFNANRFETATGLPPVFVQDNHSRSSRGVLRG
CCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCEECCCCCCEEEEECCCCCCHHHHHHH
LHYQLSQPQGKLVRVARGRVFDVAVDLRRSSATFAQWVGTELSDENQRQMWIPPGFAHGF
HHHCCCCCCCEEEEEECCEEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCE
VVLSDTADFLYKTTDYYAPEAERCVLWNDPALGIEWPISEPPLLSAKDQSGKLLAEAECF
EEEECCCCCEEECCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCEEEECCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]