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The map label for this gene is clpP [H]

Identifier: 119898161

GI number: 119898161

Start: 2050956

End: 2052833

Strand: Direct

Name: clpP [H]

Synonym: azo1870

Alternate gene names: 119898161

Gene position: 2050956-2052833 (Clockwise)

Preceding gene: 119898160

Following gene: 119898162

Centisome position: 46.87

GC content: 63.15

Gene sequence:

>1878_bases
ATGCGAACCACCGAAATCATTGGCGAAATCACCGATGTAACCGCCCGCGAAATCCTCGCCGAGCTGGCCTTGGCGGGGGA
TTCCCCGGTTGTCGTCCGCATCAACTCTCAAGGCGGCAGTGTTCAGGCTGGCGTCACCATCTACGAAGCACTGAAGGCAC
ACCGCCCAAGCGTCACCGTCGAGATTGTCGGCTGGGCCCTCTCTGCCGCGTCGTTGATCGCGATGGCTGGTCGGCCTGTC
CGCATGGCGCCTACCTCGCTGCTCATGGTTCATGCGCCCTGGACAAGCGCCACCGGCAATGCCTCCGAGCTGCGCGATAC
CGCGGCCGCGCTTGATGCCGTTGCCCGTTCCATGCGCGCCGCCTTCTCCCGCACCAAGCAACCGCCCAAGACCATCGACG
CATGGCTGACCGGCGAGCACTGGTTCACCGCAGAAGAAGCAATCGCGGCCGGTCTGGCCGACGAACTCATCCCCGAAATG
CAGGCATGCGCCCCGATGGGCGTGATGGCCTGCGCGTTCTCAATCCCTGATCACATCAAAGGAAAACTCATGGCCACACC
GACCCCTGACGCAACCGCCGCCGCTCGCCTCGCCGACCTCGAACGACGGGAAGCAATCCGAACTGACTTCGCGCCGTTCC
TGAAGCATCCTGGCGGGCAGCAGTTCATGAACCAGCTACTCGACGACAAGACTTGCACCGCTGAGAACGCCGGTCCGCGC
ATCCTGTCCTGGCTTGCATCCACCGTCGAGCCGATCGGAGCCTATCGTGCCGAATTCACTGGCGAGGACTTTGTCGATAC
GTCAGCCGGACAACTGCGGGACTTCGCCGCGGCTGCAAGCGACGCGTTGTTGATTCGCGCCGGCATGCGGGTACCGAATC
CGCACCCGTCCGCCCGCGACCTGTCGCGGATGTCTGTGGTCGATATGGCTGAGCGCCTGCTGAGTATGTCGGGCATTTCC
ACGCGCGGCATGAGTCGATCGGAAATCTTGAGCGCAGGGCTGACGCGCGGGGACTTCCCCGAGTTGCTGCTCGGTGTCGG
GAATCGCGCGCTGCGCGATGGTTACGAAACGGCGCCGAACTCGCACGCGGTCTGGACCGCTGAGCGCGAGGTCGTAGATT
TCCGTCCGCAGAACCTGCTGCAACTCTCCGAGGCGCCGGATCTTCGCCGGGTGAATGAAGGCGGTGAGTTCACGTACAGC
TACTTCTCCGAAGCGGTTGAATCGTTCTCGATCGAAACGTTCGGGCGAATCATCGCCTTGACCCGTCAGGCGTTGATCAA
CGACGACCTTGGCGCCTTTACGCGCATCCCTGAAGCCTTTGGCAAGGCCGCACGGCGACTGGAAGCCGACCACGTGTATG
CGAAGCTCACTGGCACCGGCAACCTGTCTGACGGCCTGCCGCTGTTCCATGCGGATCACAACAACCTCGGCGCCGCCGCA
GCGCTGTCCGTCGAAAGCCTGGGGGTTGCCCGCTCGGCCATGCGCCGACACAAGACCATGAATGGCCTGGGCTATCTCGA
CCTGATGCCGGCCTTTCTGATTGTGCCAACCTCGCTCGAAACCGAGGCGGAATCGCTGCTTTCCAGCCTGTCCCGCCCCG
ATGCGACTCATTCCGGCGTCGGCAATCCGTCGTGGGTTCGTTCGCTCGAACTGGTGTCCGATCCGCGCCTGGACGCCGTC
AGCGAGACTGCTTGGTATCTCGCGGCGCATCCGGCGAGTGCGGACGGGATCATCCGCGCATACCTCGCTGGAGCCGCTCG
CCCGGACATCATTACGGAGCAAGAATTCCGCGTCGACCAATCGAGCTGGAAGACTCGTCTTGATTTCGGCGTGGCGATCA
TCGACTACCGCAGCCTGTACAAGAATCCGGGCGCGTAA

Upstream 100 bases:

>100_bases
CATCACCCGCGCAATTGCGTGACATCGTGCGGCGAAATACCCCGTATTCATCGCACGGCCGCCAAGTAAAGATGCTGGCA
TCGAGACTACAGATGCCAGC

Downstream 100 bases:

>100_bases
GAACTGATCGGGCAAGCGCCGAAAGGCGCACCGGGCGCGACTGGACGGGAACCAGGCGCGCACGGCGGACACCGGACGCG
GACGCTCCCCCGCTGCAAGT

Product: endopeptidase Clp

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MRTTEIIGEITDVTAREILAELALAGDSPVVVRINSQGGSVQAGVTIYEALKAHRPSVTVEIVGWALSAASLIAMAGRPV
RMAPTSLLMVHAPWTSATGNASELRDTAAALDAVARSMRAAFSRTKQPPKTIDAWLTGEHWFTAEEAIAAGLADELIPEM
QACAPMGVMACAFSIPDHIKGKLMATPTPDATAAARLADLERREAIRTDFAPFLKHPGGQQFMNQLLDDKTCTAENAGPR
ILSWLASTVEPIGAYRAEFTGEDFVDTSAGQLRDFAAAASDALLIRAGMRVPNPHPSARDLSRMSVVDMAERLLSMSGIS
TRGMSRSEILSAGLTRGDFPELLLGVGNRALRDGYETAPNSHAVWTAEREVVDFRPQNLLQLSEAPDLRRVNEGGEFTYS
YFSEAVESFSIETFGRIIALTRQALINDDLGAFTRIPEAFGKAARRLEADHVYAKLTGTGNLSDGLPLFHADHNNLGAAA
ALSVESLGVARSAMRRHKTMNGLGYLDLMPAFLIVPTSLETEAESLLSSLSRPDATHSGVGNPSWVRSLELVSDPRLDAV
SETAWYLAAHPASADGIIRAYLAGAARPDIITEQEFRVDQSSWKTRLDFGVAIIDYRSLYKNPGA

Sequences:

>Translated_625_residues
MRTTEIIGEITDVTAREILAELALAGDSPVVVRINSQGGSVQAGVTIYEALKAHRPSVTVEIVGWALSAASLIAMAGRPV
RMAPTSLLMVHAPWTSATGNASELRDTAAALDAVARSMRAAFSRTKQPPKTIDAWLTGEHWFTAEEAIAAGLADELIPEM
QACAPMGVMACAFSIPDHIKGKLMATPTPDATAAARLADLERREAIRTDFAPFLKHPGGQQFMNQLLDDKTCTAENAGPR
ILSWLASTVEPIGAYRAEFTGEDFVDTSAGQLRDFAAAASDALLIRAGMRVPNPHPSARDLSRMSVVDMAERLLSMSGIS
TRGMSRSEILSAGLTRGDFPELLLGVGNRALRDGYETAPNSHAVWTAEREVVDFRPQNLLQLSEAPDLRRVNEGGEFTYS
YFSEAVESFSIETFGRIIALTRQALINDDLGAFTRIPEAFGKAARRLEADHVYAKLTGTGNLSDGLPLFHADHNNLGAAA
ALSVESLGVARSAMRRHKTMNGLGYLDLMPAFLIVPTSLETEAESLLSSLSRPDATHSGVGNPSWVRSLELVSDPRLDAV
SETAWYLAAHPASADGIIRAYLAGAARPDIITEQEFRVDQSSWKTRLDFGVAIIDYRSLYKNPGA
>Mature_625_residues
MRTTEIIGEITDVTAREILAELALAGDSPVVVRINSQGGSVQAGVTIYEALKAHRPSVTVEIVGWALSAASLIAMAGRPV
RMAPTSLLMVHAPWTSATGNASELRDTAAALDAVARSMRAAFSRTKQPPKTIDAWLTGEHWFTAEEAIAAGLADELIPEM
QACAPMGVMACAFSIPDHIKGKLMATPTPDATAAARLADLERREAIRTDFAPFLKHPGGQQFMNQLLDDKTCTAENAGPR
ILSWLASTVEPIGAYRAEFTGEDFVDTSAGQLRDFAAAASDALLIRAGMRVPNPHPSARDLSRMSVVDMAERLLSMSGIS
TRGMSRSEILSAGLTRGDFPELLLGVGNRALRDGYETAPNSHAVWTAEREVVDFRPQNLLQLSEAPDLRRVNEGGEFTYS
YFSEAVESFSIETFGRIIALTRQALINDDLGAFTRIPEAFGKAARRLEADHVYAKLTGTGNLSDGLPLFHADHNNLGAAA
ALSVESLGVARSAMRRHKTMNGLGYLDLMPAFLIVPTSLETEAESLLSSLSRPDATHSGVGNPSWVRSLELVSDPRLDAV
SETAWYLAAHPASADGIIRAYLAGAARPDIITEQEFRVDQSSWKTRLDFGVAIIDYRSLYKNPGA

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17538017, Length=162, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129427, Length=163, Percent_Identity=28.2208588957055, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 67285; Mature: 67285

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTEIIGEITDVTAREILAELALAGDSPVVVRINSQGGSVQAGVTIYEALKAHRPSVTV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEHHHHHHHHHHHCCCCEEE
EIVGWALSAASLIAMAGRPVRMAPTSLLMVHAPWTSATGNASELRDTAAALDAVARSMRA
EEHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AFSRTKQPPKTIDAWLTGEHWFTAEEAIAAGLADELIPEMQACAPMGVMACAFSIPDHIK
HHHHCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHC
GKLMATPTPDATAAARLADLERREAIRTDFAPFLKHPGGQQFMNQLLDDKTCTAENAGPR
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHH
ILSWLASTVEPIGAYRAEFTGEDFVDTSAGQLRDFAAAASDALLIRAGMRVPNPHPSARD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHH
LSRMSVVDMAERLLSMSGISTRGMSRSEILSAGLTRGDFPELLLGVGNRALRDGYETAPN
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCHHHHCCCCCCCC
SHAVWTAEREVVDFRPQNLLQLSEAPDLRRVNEGGEFTYSYFSEAVESFSIETFGRIIAL
CCEEEEECCHHHHCCCHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
TRQALINDDLGAFTRIPEAFGKAARRLEADHVYAKLTGTGNLSDGLPLFHADHNNLGAAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEECCCCCCCHHH
ALSVESLGVARSAMRRHKTMNGLGYLDLMPAFLIVPTSLETEAESLLSSLSRPDATHSGV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCC
GNPSWVRSLELVSDPRLDAVSETAWYLAAHPASADGIIRAYLAGAARPDIITEQEFRVDQ
CCHHHHHHHHHHCCCCCCHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHCCH
SSWKTRLDFGVAIIDYRSLYKNPGA
HHHHHHHHHCCCEEEHHHHHCCCCC
>Mature Secondary Structure
MRTTEIIGEITDVTAREILAELALAGDSPVVVRINSQGGSVQAGVTIYEALKAHRPSVTV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEHHHHHHHHHHHCCCCEEE
EIVGWALSAASLIAMAGRPVRMAPTSLLMVHAPWTSATGNASELRDTAAALDAVARSMRA
EEHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AFSRTKQPPKTIDAWLTGEHWFTAEEAIAAGLADELIPEMQACAPMGVMACAFSIPDHIK
HHHHCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHC
GKLMATPTPDATAAARLADLERREAIRTDFAPFLKHPGGQQFMNQLLDDKTCTAENAGPR
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHH
ILSWLASTVEPIGAYRAEFTGEDFVDTSAGQLRDFAAAASDALLIRAGMRVPNPHPSARD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHH
LSRMSVVDMAERLLSMSGISTRGMSRSEILSAGLTRGDFPELLLGVGNRALRDGYETAPN
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCHHHHCCCCCCCC
SHAVWTAEREVVDFRPQNLLQLSEAPDLRRVNEGGEFTYSYFSEAVESFSIETFGRIIAL
CCEEEEECCHHHHCCCHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
TRQALINDDLGAFTRIPEAFGKAARRLEADHVYAKLTGTGNLSDGLPLFHADHNNLGAAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEECCCCCCCHHH
ALSVESLGVARSAMRRHKTMNGLGYLDLMPAFLIVPTSLETEAESLLSSLSRPDATHSGV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCC
GNPSWVRSLELVSDPRLDAVSETAWYLAAHPASADGIIRAYLAGAARPDIITEQEFRVDQ
CCHHHHHHHHHHCCCCCCHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHCCH
SSWKTRLDFGVAIIDYRSLYKNPGA
HHHHHHHHHCCCEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]