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The map label for this gene is clcR [H]

Identifier: 119898126

GI number: 119898126

Start: 2013981

End: 2014892

Strand: Reverse

Name: clcR [H]

Synonym: azo1835

Alternate gene names: 119898126

Gene position: 2014892-2013981 (Counterclockwise)

Preceding gene: 119898142

Following gene: 119898125

Centisome position: 46.04

GC content: 68.86

Gene sequence:

>912_bases
ATGGATATCCGCCAGCTCCGCTACTTCATCGCCGTCGCCGAGGAGGCGAACATCGGGCGGGCCGCCACCCGGCTGCACAT
GTCGCAGCCGCCGCTGACGCGCCAGATCCAGCAACTGGAAGAAGAACTCGATACCCAGCTCTTCGTGCGCACGCCGCGCG
GCATGGAGCTGACCCAGGCGGGCACGCTGTTCCTGGCCGAGGCGCGCAACATCCGCGCGCTCATCGAACAGGCCACCGAG
CGCACCCAGCGCGCCGGGCAGGGCAAGCTCGGGCGGCTGGACGTGGCGATCTTCGGCTCGGCCATCCTCGACCGCATCCC
CAAGCTGATCCTGAATTTCCGCAACGAATACCCGGATGTGAACGTGGTGCTGCACACCATGACCAAGGCCGAGCAGATCT
CGGCCCTGCGGCAGAACCGCATCACCGTCGGCTTCAACCGCATGCTCGCGCCGCTGCCGGACATCCGCAGCGAGGTGATC
GCCACCGAGTCGCTGCTGCTCGCGGTGAACCTCAACGATCCGCTGGCGGCGCAGCCCGCGCTGCCCTTCGACGTGCTCGC
GCGGCGCCCGGTCATCCTGTTCCCCTCCGGCGCGCGGCCCAACTTCGTCGACAAGGTGCTGGCGCTGTGCGAAGCGCGCG
GCTTCCTCCCCGAAGTCGCGCAGGAGGTGGGTGACGCGGTCACCGGCGTGGCGCTGGTGGCCAGCGGCTTTGGCGTGTGC
ATGGTTCCGGAATCGGCAACGACGCTGCAGTACCCGGGCGTGGTCTACCTCCCCTTCGAGGACGCGCCCGCCGAGGCCCG
GGTGGACCTCAGCTGCATCTACCGCGCGGACGACCATTCGCCGATCCTGTCGACCTTCCTCGCATCCATCCGCGCTACCT
CAGCGGCATTGCAGGACGCGGCGGCGGCCTGA

Upstream 100 bases:

>100_bases
ACCGGCGTGCCTCATTACCGTCCAATACCAATTCAAGGCTCGCGTAATACCTTCGCGGTATGATCAATCTCCACGCCCCA
CCCAACCGGAACCCCCGCTC

Downstream 100 bases:

>100_bases
TGCGGCCGATGCTGCAACCCTGCCACCCTTCCCCTGCACCGGCCGCCCGGGCGGCACGCCGCAGGCGTATTCACCCCTCG
CGGATTAGGGTTTGCGGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ClcABD operon transcriptional activator [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDIRQLRYFIAVAEEANIGRAATRLHMSQPPLTRQIQQLEEELDTQLFVRTPRGMELTQAGTLFLAEARNIRALIEQATE
RTQRAGQGKLGRLDVAIFGSAILDRIPKLILNFRNEYPDVNVVLHTMTKAEQISALRQNRITVGFNRMLAPLPDIRSEVI
ATESLLLAVNLNDPLAAQPALPFDVLARRPVILFPSGARPNFVDKVLALCEARGFLPEVAQEVGDAVTGVALVASGFGVC
MVPESATTLQYPGVVYLPFEDAPAEARVDLSCIYRADDHSPILSTFLASIRATSAALQDAAAA

Sequences:

>Translated_303_residues
MDIRQLRYFIAVAEEANIGRAATRLHMSQPPLTRQIQQLEEELDTQLFVRTPRGMELTQAGTLFLAEARNIRALIEQATE
RTQRAGQGKLGRLDVAIFGSAILDRIPKLILNFRNEYPDVNVVLHTMTKAEQISALRQNRITVGFNRMLAPLPDIRSEVI
ATESLLLAVNLNDPLAAQPALPFDVLARRPVILFPSGARPNFVDKVLALCEARGFLPEVAQEVGDAVTGVALVASGFGVC
MVPESATTLQYPGVVYLPFEDAPAEARVDLSCIYRADDHSPILSTFLASIRATSAALQDAAAA
>Mature_303_residues
MDIRQLRYFIAVAEEANIGRAATRLHMSQPPLTRQIQQLEEELDTQLFVRTPRGMELTQAGTLFLAEARNIRALIEQATE
RTQRAGQGKLGRLDVAIFGSAILDRIPKLILNFRNEYPDVNVVLHTMTKAEQISALRQNRITVGFNRMLAPLPDIRSEVI
ATESLLLAVNLNDPLAAQPALPFDVLARRPVILFPSGARPNFVDKVLALCEARGFLPEVAQEVGDAVTGVALVASGFGVC
MVPESATTLQYPGVVYLPFEDAPAEARVDLSCIYRADDHSPILSTFLASIRATSAALQDAAAA

Specific function: Involved in regulation of chlorinated catechol metabolism. Transcriptional activator of the clcABD chlorocatechol oxidative operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=268, Percent_Identity=36.9402985074627, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI2367136, Length=293, Percent_Identity=31.740614334471, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=28.1124497991968, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788887, Length=304, Percent_Identity=27.9605263157895, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=31.2, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790399, Length=288, Percent_Identity=26.3888888888889, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI157672245, Length=261, Percent_Identity=29.8850574712644, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI87081904, Length=200, Percent_Identity=29.5, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790208, Length=290, Percent_Identity=26.8965517241379, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693105, Length=244, Percent_Identity=25, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=34.6938775510204, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787806, Length=145, Percent_Identity=31.7241379310345, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788481, Length=244, Percent_Identity=27.0491803278689, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33085; Mature: 33085

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRQLRYFIAVAEEANIGRAATRLHMSQPPLTRQIQQLEEELDTQLFVRTPRGMELTQA
CCHHHHHHHHHEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCCEECCC
GTLFLAEARNIRALIEQATERTQRAGQGKLGRLDVAIFGSAILDRIPKLILNFRNEYPDV
CCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVVLHTMTKAEQISALRQNRITVGFNRMLAPLPDIRSEVIATESLLLAVNLNDPLAAQPA
EEEEEHHHHHHHHHHHHHCCEEEEHHHHHCCCCHHHHHHHHHCEEEEEEECCCCCCCCCC
LPFDVLARRPVILFPSGARPNFVDKVLALCEARGFLPEVAQEVGDAVTGVALVASGFGVC
CCHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEE
MVPESATTLQYPGVVYLPFEDAPAEARVDLSCIYRADDHSPILSTFLASIRATSAALQDA
EECCCCCEEECCCEEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AAA
CCC
>Mature Secondary Structure
MDIRQLRYFIAVAEEANIGRAATRLHMSQPPLTRQIQQLEEELDTQLFVRTPRGMELTQA
CCHHHHHHHHHEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCCEECCC
GTLFLAEARNIRALIEQATERTQRAGQGKLGRLDVAIFGSAILDRIPKLILNFRNEYPDV
CCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVVLHTMTKAEQISALRQNRITVGFNRMLAPLPDIRSEVIATESLLLAVNLNDPLAAQPA
EEEEEHHHHHHHHHHHHHCCEEEEHHHHHCCCCHHHHHHHHHCEEEEEEECCCCCCCCCC
LPFDVLARRPVILFPSGARPNFVDKVLALCEARGFLPEVAQEVGDAVTGVALVASGFGVC
CCHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEE
MVPESATTLQYPGVVYLPFEDAPAEARVDLSCIYRADDHSPILSTFLASIRATSAALQDA
EECCCCCEEECCCEEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8419291 [H]