Click here to switch to the map view.

The map label for this gene is irgA [H]

Identifier: 119898121

GI number: 119898121

Start: 2007034

End: 2009067

Strand: Reverse

Name: irgA [H]

Synonym: azo1830

Alternate gene names: 119898121

Gene position: 2009067-2007034 (Counterclockwise)

Preceding gene: 119898125

Following gene: 119898120

Centisome position: 45.91

GC content: 66.18

Gene sequence:

>2034_bases
GTGGTCGGCCAGCGCGATGCCCAGATCGAACGCAAGCACTCGGAGATCCAGAAGATCGTCATCTCCGAGACCGAGATCGA
ACGCTACGGCGACGCCACCGTCGGCGAGGTGCTGCGGCGCCTGCCCGGCATGACCTTCACCGGGCCGGCCGGCGTCACCA
AGGACATCCGCATGCGCGGGCTGGACAAGGGCTATACCCAGTTCCTGATCAACGGCGAACCGGTGCCCGCGGCCAAGAAG
GAGCGCCAGATCCAGGTGGACCGGCTGCCGGCGGACATGATCGAGCGCATCGAGATCATCCGTAACCCGAGCGCGCTGTA
CGACGCCAACGGCATCGGCGGCACGGTGAACATCGTGCTCAAGAACCGCGCCGACGGAATCACCCGCCTGCGTGCGGCCT
ACGGCCGCAATGGCGACATGGAGGTGGGCGACGTGGTGGCGCAGTGGTCGCGCCGCTTCGACGACCTCGACGTGCTGCTC
GCCGTTTCGCACACCGTCGGCGCCGAGGATGTGGACGAGGACAAGATCGCCTACAACCCCAACGGCACCGTGAAGCAGGT
CGACCTCAAGGAGAAGCCGGTACGCAAGGACGAAACCCTGTTCGCACCGCGCTTCGTGTGGCATTTCGGCGATGACCGGC
TGACGCTGGAACCCTTCGTCTCCAAGGGCAGCGAGCGCAAGGACGAGCCGACCACCACCTACAACGCCAGCGGCGCGATC
ACCAAATCCACCGACAAGGACGAGGACAAGACGGACACCATCAGCCGCCTGGCGATGCGCTACGACGGCAAGACCGGCTG
GGGCGACTGGTTCGTGAAGGCCGGCGTGCAGGAAGCGGAAGAAAAGAAGGACGCCACCACCTACGAGTACCGGGCCAACG
GCACCCTCAGCAAGACCACGCTGGAAGACGAAACCCTGCGCGAACGCGGGGTCTATGCCGGCACCGGGCTCAGCCTCGCG
CTTGGCGGCGGCCACCGCCTCTCCGCCGGCCTCGAGTGGCGCGACGGCGACTACCGCAACCGCAAGACCAAGACCGAGAA
CGGCGCCGACAAGTCCGACGCCAAGGACCGCTTCGACATCGACGAAACCCGGCTGATCGCCTATCTGCAGGACGACTGGC
GCATCAACGCCGACCATGCGCTGACGCCCGGCGTCCGAGTCGAACGCATCTCGCGCGAATCGACCGACAGCAACGGCGTC
AGCCGCAAGAACGATCTCACCGGCACCAACCCCTCGCTGCACTACCGCTGGGGGCTGGGCGAAGACCTGAACCTGCGCGC
CAGCGTCGCGCGCACGGTGAAGCTGCCCAAGTTCGACGAACTCAACCCCTTCCTCAAACTCGAGAGCGGGGTCTACAAGG
GCGGCAATCCCGACCTCAAACCGGAAACCGCGCTCGGCTACGAACTCGGCCTGGAGCACTACTTCTGGGGCAACCGCGGC
GTGGTGGGGCTGAATTTCTACCGTCGCGATGTGGACGACTTCATCCAGAAGGAAGAACGGCTGGAGGGTGCGCTCCGGGT
GGAACGTCCCTACAACGTCGGCGAAGCCCGCTTCTGGGGCGCGGAACTCGACTGGCGCATCCCCCTGCTGCGCAGCGGCG
CGCACGAGCTGACGATCACCGGCAACCACAGCGAGATGCGCGGCCGGGTGAAGGTGGCCGGCGTGCCGGGCACCAGCGAG
GTCAAGGACATGCCGCCGCGCGTCACCAACCTCGGGCTCGACTGGCTGCATCGGCCGACGATGTGGGCCGCGGGCTTCAG
CGTGAATTACCAGCCGAACTTCACCACCGACGGCGTCAATGCCGACGGCGTGCGCGAGATCAAGCGCCGCGAGGCCGCTA
CCCAGCTCGACCTCTACCTGGGCAAGACCATCAGCGCGGAGGCCGAACTGCGGCTGATCGCCAAGAACGTGCTCGCGGTC
GACAAGGAAGAGGAAACCACCAAGTACACCAGGGCCGGCGCCCTCAGCAGCCACGAGTGGAAGGTGGAGCATTCCCGGCC
GATGCTGATGGTCACCCTGGAAAGCCGCTTCTGA

Upstream 100 bases:

>100_bases
CTTTCGCCTGAAATCCCTCTGCCTGCTCGTCGCGGGCGCCTGCTCCCCTGCCCTGGCCCAGACCACCACGGCCGATTCCA
CTGCGCTTTCCGAGGTACTC

Downstream 100 bases:

>100_bases
CCCACCGACGCTAAAGGAGTCTTCGATGAAGCTTCGTTTCGACAGCCGCAAGTGGCATATCTGGGTCAGCGTCATGCTCG
CGCTGCCCATCCTCGTCGTC

Product: putative TonB-denpendent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MVGQRDAQIERKHSEIQKIVISETEIERYGDATVGEVLRRLPGMTFTGPAGVTKDIRMRGLDKGYTQFLINGEPVPAAKK
ERQIQVDRLPADMIERIEIIRNPSALYDANGIGGTVNIVLKNRADGITRLRAAYGRNGDMEVGDVVAQWSRRFDDLDVLL
AVSHTVGAEDVDEDKIAYNPNGTVKQVDLKEKPVRKDETLFAPRFVWHFGDDRLTLEPFVSKGSERKDEPTTTYNASGAI
TKSTDKDEDKTDTISRLAMRYDGKTGWGDWFVKAGVQEAEEKKDATTYEYRANGTLSKTTLEDETLRERGVYAGTGLSLA
LGGGHRLSAGLEWRDGDYRNRKTKTENGADKSDAKDRFDIDETRLIAYLQDDWRINADHALTPGVRVERISRESTDSNGV
SRKNDLTGTNPSLHYRWGLGEDLNLRASVARTVKLPKFDELNPFLKLESGVYKGGNPDLKPETALGYELGLEHYFWGNRG
VVGLNFYRRDVDDFIQKEERLEGALRVERPYNVGEARFWGAELDWRIPLLRSGAHELTITGNHSEMRGRVKVAGVPGTSE
VKDMPPRVTNLGLDWLHRPTMWAAGFSVNYQPNFTTDGVNADGVREIKRREAATQLDLYLGKTISAEAELRLIAKNVLAV
DKEEETTKYTRAGALSSHEWKVEHSRPMLMVTLESRF

Sequences:

>Translated_677_residues
MVGQRDAQIERKHSEIQKIVISETEIERYGDATVGEVLRRLPGMTFTGPAGVTKDIRMRGLDKGYTQFLINGEPVPAAKK
ERQIQVDRLPADMIERIEIIRNPSALYDANGIGGTVNIVLKNRADGITRLRAAYGRNGDMEVGDVVAQWSRRFDDLDVLL
AVSHTVGAEDVDEDKIAYNPNGTVKQVDLKEKPVRKDETLFAPRFVWHFGDDRLTLEPFVSKGSERKDEPTTTYNASGAI
TKSTDKDEDKTDTISRLAMRYDGKTGWGDWFVKAGVQEAEEKKDATTYEYRANGTLSKTTLEDETLRERGVYAGTGLSLA
LGGGHRLSAGLEWRDGDYRNRKTKTENGADKSDAKDRFDIDETRLIAYLQDDWRINADHALTPGVRVERISRESTDSNGV
SRKNDLTGTNPSLHYRWGLGEDLNLRASVARTVKLPKFDELNPFLKLESGVYKGGNPDLKPETALGYELGLEHYFWGNRG
VVGLNFYRRDVDDFIQKEERLEGALRVERPYNVGEARFWGAELDWRIPLLRSGAHELTITGNHSEMRGRVKVAGVPGTSE
VKDMPPRVTNLGLDWLHRPTMWAAGFSVNYQPNFTTDGVNADGVREIKRREAATQLDLYLGKTISAEAELRLIAKNVLAV
DKEEETTKYTRAGALSSHEWKVEHSRPMLMVTLESRF
>Mature_677_residues
MVGQRDAQIERKHSEIQKIVISETEIERYGDATVGEVLRRLPGMTFTGPAGVTKDIRMRGLDKGYTQFLINGEPVPAAKK
ERQIQVDRLPADMIERIEIIRNPSALYDANGIGGTVNIVLKNRADGITRLRAAYGRNGDMEVGDVVAQWSRRFDDLDVLL
AVSHTVGAEDVDEDKIAYNPNGTVKQVDLKEKPVRKDETLFAPRFVWHFGDDRLTLEPFVSKGSERKDEPTTTYNASGAI
TKSTDKDEDKTDTISRLAMRYDGKTGWGDWFVKAGVQEAEEKKDATTYEYRANGTLSKTTLEDETLRERGVYAGTGLSLA
LGGGHRLSAGLEWRDGDYRNRKTKTENGADKSDAKDRFDIDETRLIAYLQDDWRINADHALTPGVRVERISRESTDSNGV
SRKNDLTGTNPSLHYRWGLGEDLNLRASVARTVKLPKFDELNPFLKLESGVYKGGNPDLKPETALGYELGLEHYFWGNRG
VVGLNFYRRDVDDFIQKEERLEGALRVERPYNVGEARFWGAELDWRIPLLRSGAHELTITGNHSEMRGRVKVAGVPGTSE
VKDMPPRVTNLGLDWLHRPTMWAAGFSVNYQPNFTTDGVNADGVREIKRREAATQLDLYLGKTISAEAELRLIAKNVLAV
DKEEETTKYTRAGALSSHEWKVEHSRPMLMVTLESRF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=525, Percent_Identity=23.8095238095238, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790405, Length=223, Percent_Identity=30.4932735426009, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788478, Length=106, Percent_Identity=34.9056603773585, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76126; Mature: 76126

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGQRDAQIERKHSEIQKIVISETEIERYGDATVGEVLRRLPGMTFTGPAGVTKDIRMRG
CCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHCCCCEEECCCCCCHHHHHHC
LDKGYTQFLINGEPVPAAKKERQIQVDRLPADMIERIEIIRNPSALYDANGIGGTVNIVL
CCCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHEECCCCCCEEEEEE
KNRADGITRLRAAYGRNGDMEVGDVVAQWSRRFDDLDVLLAVSHTVGAEDVDEDKIAYNP
ECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCEEECC
NGTVKQVDLKEKPVRKDETLFAPRFVWHFGDDRLTLEPFVSKGSERKDEPTTTYNASGAI
CCCEEEECCCCCCCCCCCCEECCEEEEEECCCCEEECHHHCCCCCCCCCCCCEECCCCCE
TKSTDKDEDKTDTISRLAMRYDGKTGWGDWFVKAGVQEAEEKKDATTYEYRANGTLSKTT
ECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHCCCCEEEEECCCCEEECC
LEDETLRERGVYAGTGLSLALGGGHRLSAGLEWRDGDYRNRKTKTENGADKSDAKDRFDI
CCHHHHHHCCCEECCCCEEEECCCCEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
DETRLIAYLQDDWRINADHALTPGVRVERISRESTDSNGVSRKNDLTGTNPSLHYRWGLG
CCEEEEEEEECCCEECCCCCCCCCCEEEHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
EDLNLRASVARTVKLPKFDELNPFLKLESGVYKGGNPDLKPETALGYELGLEHYFWGNRG
CCCCCHHHHHHEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCC
VVGLNFYRRDVDDFIQKEERLEGALRVERPYNVGEARFWGAELDWRIPLLRSGAHELTIT
EEEEHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCEECHHHHCCCEEEEEE
GNHSEMRGRVKVAGVPGTSEVKDMPPRVTNLGLDWLHRPTMWAAGFSVNYQPNFTTDGVN
CCCHHHCCEEEEEECCCCCHHHHCCCCHHHCCHHHHCCCCEEECCEEEECCCCCCCCCCC
ADGVREIKRREAATQLDLYLGKTISAEAELRLIAKNVLAVDKEEETTKYTRAGALSSHEW
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEHHHHHCCCCHHHHHHHHHCCCCCCCE
KVEHSRPMLMVTLESRF
EEECCCCEEEEEECCCC
>Mature Secondary Structure
MVGQRDAQIERKHSEIQKIVISETEIERYGDATVGEVLRRLPGMTFTGPAGVTKDIRMRG
CCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHCCCCEEECCCCCCHHHHHHC
LDKGYTQFLINGEPVPAAKKERQIQVDRLPADMIERIEIIRNPSALYDANGIGGTVNIVL
CCCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHEECCCCCCEEEEEE
KNRADGITRLRAAYGRNGDMEVGDVVAQWSRRFDDLDVLLAVSHTVGAEDVDEDKIAYNP
ECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCCEEECC
NGTVKQVDLKEKPVRKDETLFAPRFVWHFGDDRLTLEPFVSKGSERKDEPTTTYNASGAI
CCCEEEECCCCCCCCCCCCEECCEEEEEECCCCEEECHHHCCCCCCCCCCCCEECCCCCE
TKSTDKDEDKTDTISRLAMRYDGKTGWGDWFVKAGVQEAEEKKDATTYEYRANGTLSKTT
ECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHCCCCEEEEECCCCEEECC
LEDETLRERGVYAGTGLSLALGGGHRLSAGLEWRDGDYRNRKTKTENGADKSDAKDRFDI
CCHHHHHHCCCEECCCCEEEECCCCEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
DETRLIAYLQDDWRINADHALTPGVRVERISRESTDSNGVSRKNDLTGTNPSLHYRWGLG
CCEEEEEEEECCCEECCCCCCCCCCEEEHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
EDLNLRASVARTVKLPKFDELNPFLKLESGVYKGGNPDLKPETALGYELGLEHYFWGNRG
CCCCCHHHHHHEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCC
VVGLNFYRRDVDDFIQKEERLEGALRVERPYNVGEARFWGAELDWRIPLLRSGAHELTIT
EEEEHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEECCCCCEECHHHHCCCEEEEEE
GNHSEMRGRVKVAGVPGTSEVKDMPPRVTNLGLDWLHRPTMWAAGFSVNYQPNFTTDGVN
CCCHHHCCEEEEEECCCCCHHHHCCCCHHHCCHHHHCCCCEEECCEEEECCCCCCCCCCC
ADGVREIKRREAATQLDLYLGKTISAEAELRLIAKNVLAVDKEEETTKYTRAGALSSHEW
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEHHHHHCCCCHHHHHHHHHCCCCCCCE
KVEHSRPMLMVTLESRF
EEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]