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The map label for this gene is hmp [H]

Identifier: 119898119

GI number: 119898119

Start: 2005129

End: 2006316

Strand: Reverse

Name: hmp [H]

Synonym: azo1828

Alternate gene names: 119898119

Gene position: 2006316-2005129 (Counterclockwise)

Preceding gene: 119898120

Following gene: 119898116

Centisome position: 45.85

GC content: 73.74

Gene sequence:

>1188_bases
GTGGCGCGGAGAGCGCCGCAAGCGAGCGTTACAGGCCAACCGCGGCGCGGCCCCTTCGCCCGCAGCCGCCGCCGCGCAGG
CATGAAAGCGGTTGCGCTGGCGCTCGCGGCGCTTGGTCTCGCGGGCCTCGCCTTCATCGCCTTTCTGCTGGTCGACGGGC
TGCGCGCGGTGTACCAGCGGCGGCGGGAAGAACGGCGCCAGCGCCCGCTCCGGCTGGTGGTCCGCAGCCGCGAGGAAGTC
GGCGGGGAACTGCTCCGGCTCACGCTCGCCCATCCGCGCCGGCGCCCCCTGCCGGTCTTCGAAGCCGGCCAGCACCTGAT
GATGACGGCCCCCGCCGGCCGCGGTGGCGGCGCGATACGGCGGGCATACTCGCTGGCCGCATGGCATCCGCGGCCCACCT
GGTACGAACTCGGCATCAAGCGCGAAGCGCAGGGCGCGATGTCGTCGTGGGCCTGGAATGCGCTGCTGCCGGGTGCAGTT
GTGGACGTGTCGCCGCCGCGCGGCGACTTCGTCGTCGCCGATGACGAGCTCGATCTGGTGCTGATCGCCGGCGGCATCGG
CATCACGCCGATGCGCGCCATGCTGCATGCCAGCCTCGCGCGCCCGCGCGCTCGCCGCATCGTGCTGCTGCACGCCGCGC
GCCACGCCGGCACGCTGCTCTACCGGGGCGAGTTCGAGAGCCTGGCCTCGCTGAATCCGCACTTCAGCTACCTGCCGATC
GTCTCCCGTCCCGATGGGTTCTGGCGCGGCGAGCGCGGCCGGCTGGACGCACACCGGGTGCTCGCCGCCGTGCCCACGCC
GCAACAGGCGCGCTTCTACCTATGCGCCGGGCAGGCGCTGATGGAAGACCTGGGCGGCGGTCTCATCGCCGCCGGCATCG
ACCCCGCGCGCATCCACAGCGAGGCCTTCGGCGCCGCCAGCGCGGGCGGCGGCCACGGCCAGGTGATCACGCTCGAGGAC
GGCCGCCGCGTCGACACCGCCGGCGAACCCAGCCTGCTCGCCACGCTGGAAGCCCACGGCTGTGCACCGCCCTCCGATTG
CCGCGCCGGCAGTTGCGGCGAATGCCGGATGCGGCTGGACGCCGGCGCGGTGCGCTGGCTGATGGCACCGGCCTGCGCGG
TAGCGGACGGCGAGATACTGCCCTGCATCTGTCAGCCCGCGGGCGACCTGAGGTTACGTGCCGCGTGA

Upstream 100 bases:

>100_bases
ACACCGGCAAGGCCCTGCTCGGCAAGAACCTCGAATGGCTGTGGATCGACCTCGTCGGCCTGGCGATGACGCTGCTGTCG
CTGACCGGCGTCTACATGTG

Downstream 100 bases:

>100_bases
CTGCCTGCACCTACACCGGCTTCGCCACCATCAGCCAAAAGATCGCGACGAAGGCGAAAAAGGCCGGCACGCCGAGCGCG
AACCAGCCGCGAAACACGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MARRAPQASVTGQPRRGPFARSRRRAGMKAVALALAALGLAGLAFIAFLLVDGLRAVYQRRREERRQRPLRLVVRSREEV
GGELLRLTLAHPRRRPLPVFEAGQHLMMTAPAGRGGGAIRRAYSLAAWHPRPTWYELGIKREAQGAMSSWAWNALLPGAV
VDVSPPRGDFVVADDELDLVLIAGGIGITPMRAMLHASLARPRARRIVLLHAARHAGTLLYRGEFESLASLNPHFSYLPI
VSRPDGFWRGERGRLDAHRVLAAVPTPQQARFYLCAGQALMEDLGGGLIAAGIDPARIHSEAFGAASAGGGHGQVITLED
GRRVDTAGEPSLLATLEAHGCAPPSDCRAGSCGECRMRLDAGAVRWLMAPACAVADGEILPCICQPAGDLRLRAA

Sequences:

>Translated_395_residues
MARRAPQASVTGQPRRGPFARSRRRAGMKAVALALAALGLAGLAFIAFLLVDGLRAVYQRRREERRQRPLRLVVRSREEV
GGELLRLTLAHPRRRPLPVFEAGQHLMMTAPAGRGGGAIRRAYSLAAWHPRPTWYELGIKREAQGAMSSWAWNALLPGAV
VDVSPPRGDFVVADDELDLVLIAGGIGITPMRAMLHASLARPRARRIVLLHAARHAGTLLYRGEFESLASLNPHFSYLPI
VSRPDGFWRGERGRLDAHRVLAAVPTPQQARFYLCAGQALMEDLGGGLIAAGIDPARIHSEAFGAASAGGGHGQVITLED
GRRVDTAGEPSLLATLEAHGCAPPSDCRAGSCGECRMRLDAGAVRWLMAPACAVADGEILPCICQPAGDLRLRAA
>Mature_394_residues
ARRAPQASVTGQPRRGPFARSRRRAGMKAVALALAALGLAGLAFIAFLLVDGLRAVYQRRREERRQRPLRLVVRSREEVG
GELLRLTLAHPRRRPLPVFEAGQHLMMTAPAGRGGGAIRRAYSLAAWHPRPTWYELGIKREAQGAMSSWAWNALLPGAVV
DVSPPRGDFVVADDELDLVLIAGGIGITPMRAMLHASLARPRARRIVLLHAARHAGTLLYRGEFESLASLNPHFSYLPIV
SRPDGFWRGERGRLDAHRVLAAVPTPQQARFYLCAGQALMEDLGGGLIAAGIDPARIHSEAFGAASAGGGHGQVITLEDG
RRVDTAGEPSLLATLEAHGCAPPSDCRAGSCGECRMRLDAGAVRWLMAPACAVADGEILPCICQPAGDLRLRAA

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=341, Percent_Identity=26.099706744868, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788903, Length=212, Percent_Identity=29.7169811320755, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787098, Length=334, Percent_Identity=24.5508982035928, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788568, Length=64, Percent_Identity=50, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 42430; Mature: 42299

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRAPQASVTGQPRRGPFARSRRRAGMKAVALALAALGLAGLAFIAFLLVDGLRAVYQR
CCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREERRQRPLRLVVRSREEVGGELLRLTLAHPRRRPLPVFEAGQHLMMTAPAGRGGGAIR
HHHHHHCCHHHHHHHHHHHHCHHEEEEECCCCCCCCCCHHHCCCEEEEECCCCCCCHHHH
RAYSLAAWHPRPTWYELGIKREAQGAMSSWAWNALLPGAVVDVSPPRGDFVVADDELDLV
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEECCCCCEE
LIAGGIGITPMRAMLHASLARPRARRIVLLHAARHAGTLLYRGEFESLASLNPHFSYLPI
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCHHHHHHCCCCCEEEEE
VSRPDGFWRGERGRLDAHRVLAAVPTPQQARFYLCAGQALMEDLGGGLIAAGIDPARIHS
EECCCCCCCCCCCCCCHHHEEEECCCCCCCEEEEECCHHHHHHHCCCEEEECCCHHHHHH
EAFGAASAGGGHGQVITLEDGRRVDTAGEPSLLATLEAHGCAPPSDCRAGSCGECRMRLD
HHCCCCCCCCCCCEEEEECCCCEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHEEEEC
AGAVRWLMAPACAVADGEILPCICQPAGDLRLRAA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECC
>Mature Secondary Structure 
ARRAPQASVTGQPRRGPFARSRRRAGMKAVALALAALGLAGLAFIAFLLVDGLRAVYQR
CCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREERRQRPLRLVVRSREEVGGELLRLTLAHPRRRPLPVFEAGQHLMMTAPAGRGGGAIR
HHHHHHCCHHHHHHHHHHHHCHHEEEEECCCCCCCCCCHHHCCCEEEEECCCCCCCHHHH
RAYSLAAWHPRPTWYELGIKREAQGAMSSWAWNALLPGAVVDVSPPRGDFVVADDELDLV
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEECCCCCEE
LIAGGIGITPMRAMLHASLARPRARRIVLLHAARHAGTLLYRGEFESLASLNPHFSYLPI
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCHHHHHHCCCCCEEEEE
VSRPDGFWRGERGRLDAHRVLAAVPTPQQARFYLCAGQALMEDLGGGLIAAGIDPARIHS
EECCCCCCCCCCCCCCHHHEEEECCCCCCCEEEEECCHHHHHHHCCCEEEECCCHHHHHH
EAFGAASAGGGHGQVITLEDGRRVDTAGEPSLLATLEAHGCAPPSDCRAGSCGECRMRLD
HHCCCCCCCCCCCEEEEECCCCEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHEEEEC
AGAVRWLMAPACAVADGEILPCICQPAGDLRLRAA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377 [H]