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The map label for this gene is cioA [H]

Identifier: 119898062

GI number: 119898062

Start: 1938905

End: 1940323

Strand: Direct

Name: cioA [H]

Synonym: azo1771

Alternate gene names: 119898062

Gene position: 1938905-1940323 (Clockwise)

Preceding gene: 119898061

Following gene: 119898063

Centisome position: 44.31

GC content: 68.92

Gene sequence:

>1419_bases
ATGGAGGCCGTGGGCGATGCGGTGATGCTGGCGCGGGTGCAGTTTGCCGCCAACATCACCTTCCACATCCTGTTCCCCGC
GATCACCATCGCGCTCGCCTGGGTGCTGCTGTACTTCCGCGTGCGTTACAACCGCGGCGGCGGCGACGCCTGGCTGGATG
CCTACCGCTTCTGGGTCAAGGTGTTCGCGCTCACGTTCGCCATCGGCATCGTCAGCGGGGTGACGATGAGCTTCCAGTTC
GGCACCAACTGGCCGGGCTACATGGAAACCGTGGGCAACATCGCCGGCCCGCTGCTCGCCTACGAGGTGCTCACTGCGTT
CTTTCTGGAGGCGAGCTTTCTCGGGATCATGCTGTTCGGCGTGGGCCGCGTCAGCCGGCGGGTGCATACGCTGGCCACCT
TTCTGGTGGCGGCCGGCACCACGCTGTCGGCGTTCTGGATCCTGGCGCTCAACTCGTGGATGCAGACGCCGGTGGGCTTC
GAGATGATCGAGGGCCGCGCCTACGCCACCGACTGGCTCGCGATCCTGTTCAACCCGTCGTTTCCGTACCGCTTCACCCA
CATGGTGATCGCTTCCGGCCTGACCACGGCCTTTCTGGTGGCGGGGGTTTCAGCGTGGCGCTGGCGCCGCGGCGAACGCG
GCGGCGACGTGCGCGCCGCGCTGCGCACCGGGGTGGTGATGGCCGCGACGCTGATTCCGCTGCAGATCGTGGTGGGCGAC
CTGCACGGCCTCAACACCTTCCACCACCAGCCCGCCAAGCTGGCCGCGATGGAGGGCATCTGGGAGACCCAGCGCGGCGC
GGCGGCGGTGTTGTTCGGCCTGCCGGACGAGGCCGCGCAGCGCAACCGTTACGAGGTGGCGATTCCCGGCCTGGCCTCGC
TCTACCTCGGCCATTCCTGGGATGCGGAGATTCGCGGGCTGAAGGACTTTCCCGGCGCGCATCCGCCGGTGGCGCCGGTG
TTCTGGGCCTTCCGCATCATGGTGGGGGTGGGTCTGCTAATGCTGGCGGTGTCGTGGTACGCCCTGTGGGACATGCGCCG
CCGCGGCGAACCCGGCCCGCTCGCCAGCCGCGCGCTGGTGCTGATGACCTTTTCGGGCTGGGTTGCGCTGGTGGCCGGTT
GGTACGTCACCGAGATCGGCCGCCAGCCGTGGCTGGTGTACGGCGTGCTGAGCACCGCCGAGGCCGCGTCCACCGTGCCG
GCCGGGCGCATCGGGCTGACGCTGGCGATGTACCTGACGCTGTACGCGGCGCTGCTGACCGCCTTCATCTCGGTGGTGTT
CCACCTGGCGCGCAAGGCGGGCGAGGGCGAGCGCGCCAAGGACATGAACCCGGTCAACGATCCTTTCCGCGCCGGGGTTG
GCGTGCTGGCACCCGAACCGGCGGGGCCGGATATCGAAGACAGGGGCGGCCATGCCTGA

Upstream 100 bases:

>100_bases
ACCGCGACGCGCTGCGTGCGCTGCCAGTCGCTGTACGAGCGCACCCACGCCGCGCTGCCGGAAGTGTCGCCGGCGCGGGA
AGACTAGGCGGACCGGCGCG

Downstream 100 bases:

>100_bases
TCTCTCCCAACCCGCCGGCTGGCTGCCGCTGGTGTTCCTGCTGGTGATGGGGCTGGCGATCCTGGTGTACGTGGTGCTGG
ACGGCTACGACCTTGGCCTC

Product: cyanide insensitive terminal oxidase subunit I

Products: NA

Alternate protein names: Cytochrome d ubiquinol oxidase subunit I [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MEAVGDAVMLARVQFAANITFHILFPAITIALAWVLLYFRVRYNRGGGDAWLDAYRFWVKVFALTFAIGIVSGVTMSFQF
GTNWPGYMETVGNIAGPLLAYEVLTAFFLEASFLGIMLFGVGRVSRRVHTLATFLVAAGTTLSAFWILALNSWMQTPVGF
EMIEGRAYATDWLAILFNPSFPYRFTHMVIASGLTTAFLVAGVSAWRWRRGERGGDVRAALRTGVVMAATLIPLQIVVGD
LHGLNTFHHQPAKLAAMEGIWETQRGAAAVLFGLPDEAAQRNRYEVAIPGLASLYLGHSWDAEIRGLKDFPGAHPPVAPV
FWAFRIMVGVGLLMLAVSWYALWDMRRRGEPGPLASRALVLMTFSGWVALVAGWYVTEIGRQPWLVYGVLSTAEAASTVP
AGRIGLTLAMYLTLYAALLTAFISVVFHLARKAGEGERAKDMNPVNDPFRAGVGVLAPEPAGPDIEDRGGHA

Sequences:

>Translated_472_residues
MEAVGDAVMLARVQFAANITFHILFPAITIALAWVLLYFRVRYNRGGGDAWLDAYRFWVKVFALTFAIGIVSGVTMSFQF
GTNWPGYMETVGNIAGPLLAYEVLTAFFLEASFLGIMLFGVGRVSRRVHTLATFLVAAGTTLSAFWILALNSWMQTPVGF
EMIEGRAYATDWLAILFNPSFPYRFTHMVIASGLTTAFLVAGVSAWRWRRGERGGDVRAALRTGVVMAATLIPLQIVVGD
LHGLNTFHHQPAKLAAMEGIWETQRGAAAVLFGLPDEAAQRNRYEVAIPGLASLYLGHSWDAEIRGLKDFPGAHPPVAPV
FWAFRIMVGVGLLMLAVSWYALWDMRRRGEPGPLASRALVLMTFSGWVALVAGWYVTEIGRQPWLVYGVLSTAEAASTVP
AGRIGLTLAMYLTLYAALLTAFISVVFHLARKAGEGERAKDMNPVNDPFRAGVGVLAPEPAGPDIEDRGGHA
>Mature_472_residues
MEAVGDAVMLARVQFAANITFHILFPAITIALAWVLLYFRVRYNRGGGDAWLDAYRFWVKVFALTFAIGIVSGVTMSFQF
GTNWPGYMETVGNIAGPLLAYEVLTAFFLEASFLGIMLFGVGRVSRRVHTLATFLVAAGTTLSAFWILALNSWMQTPVGF
EMIEGRAYATDWLAILFNPSFPYRFTHMVIASGLTTAFLVAGVSAWRWRRGERGGDVRAALRTGVVMAATLIPLQIVVGD
LHGLNTFHHQPAKLAAMEGIWETQRGAAAVLFGLPDEAAQRNRYEVAIPGLASLYLGHSWDAEIRGLKDFPGAHPPVAPV
FWAFRIMVGVGLLMLAVSWYALWDMRRRGEPGPLASRALVLMTFSGWVALVAGWYVTEIGRQPWLVYGVLSTAEAASTVP
AGRIGLTLAMYLTLYAALLTAFISVVFHLARKAGEGERAKDMNPVNDPFRAGVGVLAPEPAGPDIEDRGGHA

Specific function: Cytochrome Oxidase Subunit. [C]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=307, Percent_Identity=38.1107491856677, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87081779, Length=312, Percent_Identity=36.5384615384615, Blast_Score=201, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.-

Molecular weight: Translated: 51502; Mature: 51502

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAVGDAVMLARVQFAANITFHILFPAITIALAWVLLYFRVRYNRGGGDAWLDAYRFWVK
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VFALTFAIGIVSGVTMSFQFGTNWPGYMETVGNIAGPLLAYEVLTAFFLEASFLGIMLFG
HHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGRVSRRVHTLATFLVAAGTTLSAFWILALNSWMQTPVGFEMIEGRAYATDWLAILFNPS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCEECCEEEEEEECCC
FPYRFTHMVIASGLTTAFLVAGVSAWRWRRGERGGDVRAALRTGVVMAATLIPLQIVVGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LHGLNTFHHQPAKLAAMEGIWETQRGAAAVLFGLPDEAAQRNRYEVAIPGLASLYLGHSW
HHCCCHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCEEEECCCHHHHHHCCCC
DAEIRGLKDFPGAHPPVAPVFWAFRIMVGVGLLMLAVSWYALWDMRRRGEPGPLASRALV
CHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEE
LMTFSGWVALVAGWYVTEIGRQPWLVYGVLSTAEAASTVPAGRIGLTLAMYLTLYAALLT
EEEHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AFISVVFHLARKAGEGERAKDMNPVNDPFRAGVGVLAPEPAGPDIEDRGGHA
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEAVGDAVMLARVQFAANITFHILFPAITIALAWVLLYFRVRYNRGGGDAWLDAYRFWVK
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VFALTFAIGIVSGVTMSFQFGTNWPGYMETVGNIAGPLLAYEVLTAFFLEASFLGIMLFG
HHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGRVSRRVHTLATFLVAAGTTLSAFWILALNSWMQTPVGFEMIEGRAYATDWLAILFNPS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCEECCEEEEEEECCC
FPYRFTHMVIASGLTTAFLVAGVSAWRWRRGERGGDVRAALRTGVVMAATLIPLQIVVGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LHGLNTFHHQPAKLAAMEGIWETQRGAAAVLFGLPDEAAQRNRYEVAIPGLASLYLGHSW
HHCCCHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCEEEECCCHHHHHHCCCC
DAEIRGLKDFPGAHPPVAPVFWAFRIMVGVGLLMLAVSWYALWDMRRRGEPGPLASRALV
CHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEE
LMTFSGWVALVAGWYVTEIGRQPWLVYGVLSTAEAASTVPAGRIGLTLAMYLTLYAALLT
EEEHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AFISVVFHLARKAGEGERAKDMNPVNDPFRAGVGVLAPEPAGPDIEDRGGHA
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]