Click here to switch to the map view.

The map label for this gene is radA [H]

Identifier: 119898007

GI number: 119898007

Start: 1881549

End: 1882919

Strand: Direct

Name: radA [H]

Synonym: azo1716

Alternate gene names: 119898007

Gene position: 1881549-1882919 (Clockwise)

Preceding gene: 119898006

Following gene: 119898009

Centisome position: 43.0

GC content: 69.66

Gene sequence:

>1371_bases
ATGGCCAAGGCGAAGACGGTTTTCGTCTGCACCGAATGCGGTGCGCAGGCGCTGCGCTGGCAGGGCCAGTGTCCGCAATG
CAATGCCTGGAACACCCTGGTCGAGAGCATCGCCGAGCCCGCCCCCAGCGCCGGCTCGCGCTTCGCCGCGCTGGCGGGCA
CCACCGCCCGGCTGCAGGCGCTGTCCGAACTCGAACCCAAGGAGGAGCCGCGCACGCCCACGGGCATCGACGAATTCGAC
CGCGTGCTGGGCGGGGGGCTGGTCGCGGGCGGCGTGGTATTGATCGGCGGCGACCCCGGCATCGGCAAATCCACACTGCT
GCTGCAGGCGCTGTCGCACCTGGCCGGCACGCAGGCGGCGGTCTATGTCAGCGGTGAAGAGTCCGGCGAGCAGGTGGCGC
TGCGCGCGCAACGCCTGCAACTGTCGGCCAGCACGCTGCAACTGCTGGCCGAGATCAACCTGGAACGCATCCTCGCCACG
CTGCGCGAGGCCAAGCCGCGCGTCGCGGTGATCGACTCGATCCAGACCATCTATTCCGAAGCGCTGCAGTCCGCGCCCGG
TTCGGTTGCGCAGGTGCGCGAGTGCGCCGCCCAGCTCACCCGCTACGCCAAGCAGAGCGGCGCCGCGCTGATCATCGTGG
GCCACGTCACCAAGGACGGTGCGCTCGCCGGCCCGCGCGTGCTGGAGCACATCGTCGATACCGTGCTGTACTTCGAGGGC
GATACCCACTCCAGCTTCCGGCTGGTGCGGGCGTTCAAGAACCGCTTCGGCGCGGTGAACGAACTCGGCGTGTTCGCGAT
GACCGAGCGCGGCCTGCGCGGGGTCTCCAATCCGTCGGCAATCTTCCTGTCGCAGCACGCCGAGCGCGTTTCCGGCAGCT
GCGTGCTGATCACGCAGGAGGGCACGCGCCCGCTGCTGGTCGAAATCCAGGCGCTGGTCGACGCCGCTCACAGCCCCAAC
CCGCGCCGCCTCAGCGTGGGGCTGGAGCAGACCCGGCTGGCGATGCTGCTCGCGGTGCTGCACCGTCACGCCGGCATCGT
CTGTTTCGACCAGGACGTGTTCGTCAATGCGGTCGGCGGGGTCAAGATCGCCGAACCGGCGGCCGATCTGGCGATCCTGC
TCGCCATCGTGTCTTCGCTGCGCGACAAGCCCTTGAAGCACGGCCTCGCGGTGTTTGGCGAAGTCGGCCTGGCGGGCGAA
ATCCGGCCCGCGCCGCGCGGGCAGGAGCGGCTGAAGGAGGCGGCCAAGCTCGGTTTCTCCGCCGCCATCGTGCCGCGCGC
CAACCTGCCGCGTCAGGCCGTCGACGGCCTGCAGGTAATCGGCGTAGACCGCATCGAGGAAGCGCTGGAGCGCGTGCGCG
AGCTGGAATAG

Upstream 100 bases:

>100_bases
TCCCGCGCGACAAGTTCCGCTCGCGCCTGATCACCACCTTCGCCGACCATGCCTGTGAGGTGCTCGCCGCGCTCGCCGGC
GAGTTCGCCACCGACCACTG

Downstream 100 bases:

>100_bases
GCGCTCCGCGCCGAGGCCGCCCGCCGCGCACCTTCAAGTCCCCCGCAGCGGGGGCGCCGCAGGCTCAGCGCGGCCCGGGC
TTGGTCCGCAAGCCGGGTGG

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAKAKTVFVCTECGAQALRWQGQCPQCNAWNTLVESIAEPAPSAGSRFAALAGTTARLQALSELEPKEEPRTPTGIDEFD
RVLGGGLVAGGVVLIGGDPGIGKSTLLLQALSHLAGTQAAVYVSGEESGEQVALRAQRLQLSASTLQLLAEINLERILAT
LREAKPRVAVIDSIQTIYSEALQSAPGSVAQVRECAAQLTRYAKQSGAALIIVGHVTKDGALAGPRVLEHIVDTVLYFEG
DTHSSFRLVRAFKNRFGAVNELGVFAMTERGLRGVSNPSAIFLSQHAERVSGSCVLITQEGTRPLLVEIQALVDAAHSPN
PRRLSVGLEQTRLAMLLAVLHRHAGIVCFDQDVFVNAVGGVKIAEPAADLAILLAIVSSLRDKPLKHGLAVFGEVGLAGE
IRPAPRGQERLKEAAKLGFSAAIVPRANLPRQAVDGLQVIGVDRIEEALERVRELE

Sequences:

>Translated_456_residues
MAKAKTVFVCTECGAQALRWQGQCPQCNAWNTLVESIAEPAPSAGSRFAALAGTTARLQALSELEPKEEPRTPTGIDEFD
RVLGGGLVAGGVVLIGGDPGIGKSTLLLQALSHLAGTQAAVYVSGEESGEQVALRAQRLQLSASTLQLLAEINLERILAT
LREAKPRVAVIDSIQTIYSEALQSAPGSVAQVRECAAQLTRYAKQSGAALIIVGHVTKDGALAGPRVLEHIVDTVLYFEG
DTHSSFRLVRAFKNRFGAVNELGVFAMTERGLRGVSNPSAIFLSQHAERVSGSCVLITQEGTRPLLVEIQALVDAAHSPN
PRRLSVGLEQTRLAMLLAVLHRHAGIVCFDQDVFVNAVGGVKIAEPAADLAILLAIVSSLRDKPLKHGLAVFGEVGLAGE
IRPAPRGQERLKEAAKLGFSAAIVPRANLPRQAVDGLQVIGVDRIEEALERVRELE
>Mature_455_residues
AKAKTVFVCTECGAQALRWQGQCPQCNAWNTLVESIAEPAPSAGSRFAALAGTTARLQALSELEPKEEPRTPTGIDEFDR
VLGGGLVAGGVVLIGGDPGIGKSTLLLQALSHLAGTQAAVYVSGEESGEQVALRAQRLQLSASTLQLLAEINLERILATL
REAKPRVAVIDSIQTIYSEALQSAPGSVAQVRECAAQLTRYAKQSGAALIIVGHVTKDGALAGPRVLEHIVDTVLYFEGD
THSSFRLVRAFKNRFGAVNELGVFAMTERGLRGVSNPSAIFLSQHAERVSGSCVLITQEGTRPLLVEIQALVDAAHSPNP
RRLSVGLEQTRLAMLLAVLHRHAGIVCFDQDVFVNAVGGVKIAEPAADLAILLAIVSSLRDKPLKHGLAVFGEVGLAGEI
RPAPRGQERLKEAAKLGFSAAIVPRANLPRQAVDGLQVIGVDRIEEALERVRELE

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=460, Percent_Identity=59.7826086956522, Blast_Score=542, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 48395; Mature: 48264

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAKTVFVCTECGAQALRWQGQCPQCNAWNTLVESIAEPAPSAGSRFAALAGTTARLQA
CCCCCEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHH
LSELEPKEEPRTPTGIDEFDRVLGGGLVAGGVVLIGGDPGIGKSTLLLQALSHLAGTQAA
HHHCCCCCCCCCCCCHHHHHHHHCCCEEECCEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VYVSGEESGEQVALRAQRLQLSASTLQLLAEINLERILATLREAKPRVAVIDSIQTIYSE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALQSAPGSVAQVRECAAQLTRYAKQSGAALIIVGHVTKDGALAGPRVLEHIVDTVLYFEG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHEECC
DTHSSFRLVRAFKNRFGAVNELGVFAMTERGLRGVSNPSAIFLSQHAERVSGSCVLITQE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCEEEEECC
GTRPLLVEIQALVDAAHSPNPRRLSVGLEQTRLAMLLAVLHRHAGIVCFDQDVFVNAVGG
CCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCC
VKIAEPAADLAILLAIVSSLRDKPLKHGLAVFGEVGLAGEIRPAPRGQERLKEAAKLGFS
CEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCC
AAIVPRANLPRQAVDGLQVIGVDRIEEALERVRELE
EEECCCCCCCHHHHCCHHEECHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKAKTVFVCTECGAQALRWQGQCPQCNAWNTLVESIAEPAPSAGSRFAALAGTTARLQA
CCCCEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHH
LSELEPKEEPRTPTGIDEFDRVLGGGLVAGGVVLIGGDPGIGKSTLLLQALSHLAGTQAA
HHHCCCCCCCCCCCCHHHHHHHHCCCEEECCEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VYVSGEESGEQVALRAQRLQLSASTLQLLAEINLERILATLREAKPRVAVIDSIQTIYSE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALQSAPGSVAQVRECAAQLTRYAKQSGAALIIVGHVTKDGALAGPRVLEHIVDTVLYFEG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHEECC
DTHSSFRLVRAFKNRFGAVNELGVFAMTERGLRGVSNPSAIFLSQHAERVSGSCVLITQE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCEEEEECC
GTRPLLVEIQALVDAAHSPNPRRLSVGLEQTRLAMLLAVLHRHAGIVCFDQDVFVNAVGG
CCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCC
VKIAEPAADLAILLAIVSSLRDKPLKHGLAVFGEVGLAGEIRPAPRGQERLKEAAKLGFS
CEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCC
AAIVPRANLPRQAVDGLQVIGVDRIEEALERVRELE
EEECCCCCCCHHHHCCHHEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]