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The map label for this gene is etfA1 [H]

Identifier: 119897991

GI number: 119897991

Start: 1868313

End: 1869248

Strand: Direct

Name: etfA1 [H]

Synonym: azo1700

Alternate gene names: 119897991

Gene position: 1868313-1869248 (Clockwise)

Preceding gene: 119897990

Following gene: 119897992

Centisome position: 42.69

GC content: 69.44

Gene sequence:

>936_bases
ATGGCCATTCTTGTCCTTGCCGAACACGACAACCACACCCTCAAGGCTGCCACGCTCAACACGGTGACGGCCGCCGCCAA
GATCGGCGGTGACATCCATGTTCTCGTCGCGGGCAGCAACTGCGCCGGCGCGGCCGAAGCCGCTGCCAAGGTGGCGGGCG
TCGCCAAGGTGCTGGTGGCCGACGCCCCGCATCTGGACGCCCAGCTCGCCGAGAACGTCAGCGCGCTGCTGAAGAACCTC
GCCGGCAACTACAGCCACCTCCTCGCGCCGTCGACCTCGGCGGGCAAGAACACGCTGCCGCGCGTGGCCGCGCTGCTCGA
CGTCGCGCAGATCAGCGACATCGTCGGTGTGGAAGCGGCCGACACCTTCGTGCGCCCGATCTACGCCGGCAACGCGCTCG
CCACCGTCAAGAGCGCCGACGCGGTCAAGGTCATCACCGTGCGCACCACCGCGTTCGAGGCGGCTGCGGCGGAAGGCGGC
GCGGCCGCGATCGAAGCGGTCGCCACCGGTGCGGATGCCGGCCAGTCCAACCTCGTCGGCCGCGAGATCACCAAGAGCGC
GCGCCCCGAACTCGGTGCCGCCAAGATCATCGTCTCCGGCGGTCGCGGCCTGGGCAGCGGCGAGAACTACACCACGCTGC
TCGAACCGCTCGCCGACAAGCTCGGCGCCGCGCTCGGCGCCAGCCGCGCGGCGGTCGATGCGGGCTACGTGCCCAACGAC
TACCAGGTCGGCCAGACCGGCAAGATCGTCGCGCCGCAGCTCTACATCGCGGTCGGCATCTCGGGTGCCATCCAGCACCT
GGCCGGCATGAAGGACTCCAAGGTGATCGTGGCGATCAACAAGGACCCCGAAGCGCCGATCTTCCAGGTGGCCGACTATG
GACTGGTGGGTGACCTGTTCGAGGTGGTGCCGGCGCTGACCGCGGCGGTCGGTTAA

Upstream 100 bases:

>100_bases
CGCTGAAAGTGACCGAGCCGCCCAAGCGCAGCGCCGGGGTGCGGGTCGCCGATGTGGCCCAGCTGGTCGACAAACTGAAG
AACGAAGCGAAGGTGCTCTG

Downstream 100 bases:

>100_bases
AGACCGCTCGCGGGGTTCCGGAGCCGCGGATCACGCATGTGAACCTGTCTGCGTCGCTGTTCGATACGGGTTGGCATTGG
GCAATGTTCTTCATTGCTCT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MAILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCAGAAEAAAKVAGVAKVLVADAPHLDAQLAENVSALLKNL
AGNYSHLLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAAAEGG
AAAIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAAVG

Sequences:

>Translated_311_residues
MAILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCAGAAEAAAKVAGVAKVLVADAPHLDAQLAENVSALLKNL
AGNYSHLLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAAAEGG
AAAIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAAVG
>Mature_310_residues
AILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCAGAAEAAAKVAGVAKVLVADAPHLDAQLAENVSALLKNLA
GNYSHLLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAAAEGGA
AAIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAAVG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=60.7843137254902, Blast_Score=358, Evalue=3e-99,
Organism=Homo sapiens, GI189181759, Length=265, Percent_Identity=62.2641509433962, Blast_Score=314, Evalue=6e-86,
Organism=Escherichia coli, GI1786226, Length=239, Percent_Identity=37.2384937238494, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787990, Length=255, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082157, Length=231, Percent_Identity=31.6017316017316, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=57.8778135048232, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6325261, Length=294, Percent_Identity=45.9183673469388, Blast_Score=256, Evalue=4e-69,
Organism=Drosophila melanogaster, GI17136898, Length=309, Percent_Identity=63.4304207119741, Blast_Score=366, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24652801, Length=309, Percent_Identity=63.4304207119741, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31037; Mature: 30905

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCAGAAEAAAKVAGVAKVLVA
CEEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DAPHLDAQLAENVSALLKNLAGNYSHLLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAA
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
DTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAAAEGGAAAIEAVATGADAGQSNLVG
HHHHHHHHCCCEEEEEECCCCEEEEEEEEHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCH
REITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPND
HHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHH
EVVPALTAAVG
HHHHHHHHHCC
>Mature Secondary Structure 
AILVLAEHDNHTLKAATLNTVTAAAKIGGDIHVLVAGSNCAGAAEAAAKVAGVAKVLVA
EEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DAPHLDAQLAENVSALLKNLAGNYSHLLAPSTSAGKNTLPRVAALLDVAQISDIVGVEAA
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
DTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAAAEGGAAAIEAVATGADAGQSNLVG
HHHHHHHHCCCEEEEEECCCCEEEEEEEEHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCH
REITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPND
HHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHH
EVVPALTAAVG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]