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The map label for this gene is selU [H]

Identifier: 119897955

GI number: 119897955

Start: 1827218

End: 1828321

Strand: Reverse

Name: selU [H]

Synonym: azo1664

Alternate gene names: 119897955

Gene position: 1828321-1827218 (Counterclockwise)

Preceding gene: 119897957

Following gene: 119897953

Centisome position: 41.78

GC content: 68.03

Gene sequence:

>1104_bases
ATGTTCCAGAAAGGAGTGGCGCCGCAGGACGCGGCACCCGAAACCATGCAGAAAGGCGTTGCGACCGTAGCACAGCGAGG
CGAGTTTGACGAGATCATCGACGCCCGCACCCCGGCCGAGTTCGCCGAAGACCATATTCCCGGCGCGATCAACCTGCCGG
TGCTGGACGACGCGCAGCGCGCCACCGTCGGCACCATCTACGTGCAGCAGTCCGCCTTCGAAGCGCGCCGCATCGGCGCC
GCGATGGTGGCCGAGAACATCGCCCGCCACCTCTATGCCCACCTGCAGGACAAACCGAAGCGCTGGCGTCCGCTGGTGTA
TTGCTGGCGCGGCGGCCAGCGCAGCGGCGCCTTCACCACCTGGCTGCGGATGATCGGCTGGGACGCCTGCCAGCTCGAAG
GCGGCTACAAGCGCTTCCGTCACGTCGTGATCGAAGAGCTGGCACAGCTCGCACCGGCGTTCGACTGGCGCGTCGTCGGC
GGCGCCACCGGCAGCGCCAAGACGCGCATCCTCGAGGCACTGGCCGCTGCCGGTGCCCAGGTCGTGGACCTCGAAGGACT
GGCGGCGCACAAGGGTTCGGTGCTGGGTGGGCTGCCGGATCGCCCGCAACCCACCCAGAAGGGTTTCGAAACCGCCCTGC
ACGCGGTGCTGAGCGGACTCGATCCGGCCCGCCCGGTGTTCGTCGAGGCGGAAAGCCGCAAGATCGGCCGCATCTTCCTG
CCCGATCCATTGCTGTTCGCCATCCGCAAAGCACCCTGCATCGTGGTGGAGGCGAGCCGCGAGGCGCGGCTGGAATACCT
GGTGCGCGACTACGCCTACCTCGGCGACGATACTGCCCGCCTGCAGGGCCTGATCGAGAAGCTGCGCGGACTGCAGAGCA
ACGAGCGCATCGACAACTGGCTCGCGCTGGCGCAGGCGCGTGCGCTGCCGGCCTTGTTCGGCGAACTCGTCGACCACCAC
TACGACCCGCTCTACCGGCGATCGCAAAACGGCAATTACCAAGGCTACGCGGCGGCGCCGCGCATCGTCACCGACGACCT
CGGGCCGCACAACATACCGGCGCTCGCGCGCGAGATCCTCTCGATGGCGACGAACCGGGACTGA

Upstream 100 bases:

>100_bases
GCCCGGCGGCATGCCGGAGAGCATTTCGGCGAGCACCGCGGGCGCGATTTTGCAGCCGCATCCGCCGCCGTGGGAAAATT
GCGTGAGCCGGATTTTTTCC

Downstream 100 bases:

>100_bases
GAATCAGGGCAAGGGAATCAGACCGCCGCCATTGACCGCGCAGATGCGCTGCAGCGCGGCCGGGCGCGGCTGGGCGACCT
CGCCCTGCTCGAACGCGACC

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MFQKGVAPQDAAPETMQKGVATVAQRGEFDEIIDARTPAEFAEDHIPGAINLPVLDDAQRATVGTIYVQQSAFEARRIGA
AMVAENIARHLYAHLQDKPKRWRPLVYCWRGGQRSGAFTTWLRMIGWDACQLEGGYKRFRHVVIEELAQLAPAFDWRVVG
GATGSAKTRILEALAAAGAQVVDLEGLAAHKGSVLGGLPDRPQPTQKGFETALHAVLSGLDPARPVFVEAESRKIGRIFL
PDPLLFAIRKAPCIVVEASREARLEYLVRDYAYLGDDTARLQGLIEKLRGLQSNERIDNWLALAQARALPALFGELVDHH
YDPLYRRSQNGNYQGYAAAPRIVTDDLGPHNIPALAREILSMATNRD

Sequences:

>Translated_367_residues
MFQKGVAPQDAAPETMQKGVATVAQRGEFDEIIDARTPAEFAEDHIPGAINLPVLDDAQRATVGTIYVQQSAFEARRIGA
AMVAENIARHLYAHLQDKPKRWRPLVYCWRGGQRSGAFTTWLRMIGWDACQLEGGYKRFRHVVIEELAQLAPAFDWRVVG
GATGSAKTRILEALAAAGAQVVDLEGLAAHKGSVLGGLPDRPQPTQKGFETALHAVLSGLDPARPVFVEAESRKIGRIFL
PDPLLFAIRKAPCIVVEASREARLEYLVRDYAYLGDDTARLQGLIEKLRGLQSNERIDNWLALAQARALPALFGELVDHH
YDPLYRRSQNGNYQGYAAAPRIVTDDLGPHNIPALAREILSMATNRD
>Mature_367_residues
MFQKGVAPQDAAPETMQKGVATVAQRGEFDEIIDARTPAEFAEDHIPGAINLPVLDDAQRATVGTIYVQQSAFEARRIGA
AMVAENIARHLYAHLQDKPKRWRPLVYCWRGGQRSGAFTTWLRMIGWDACQLEGGYKRFRHVVIEELAQLAPAFDWRVVG
GATGSAKTRILEALAAAGAQVVDLEGLAAHKGSVLGGLPDRPQPTQKGFETALHAVLSGLDPARPVFVEAESRKIGRIFL
PDPLLFAIRKAPCIVVEASREARLEYLVRDYAYLGDDTARLQGLIEKLRGLQSNERIDNWLALAQARALPALFGELVDHH
YDPLYRRSQNGNYQGYAAAPRIVTDDLGPHNIPALAREILSMATNRD

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=351, Percent_Identity=33.9031339031339, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 40446; Mature: 40446

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00380 RHODANESE_1 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQKGVAPQDAAPETMQKGVATVAQRGEFDEIIDARTPAEFAEDHIPGAINLPVLDDAQR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCC
ATVGTIYVQQSAFEARRIGAAMVAENIARHLYAHLQDKPKRWRPLVYCWRGGQRSGAFTT
CEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHH
WLRMIGWDACQLEGGYKRFRHVVIEELAQLAPAFDWRVVGGATGSAKTRILEALAAAGAQ
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCE
VVDLEGLAAHKGSVLGGLPDRPQPTQKGFETALHAVLSGLDPARPVFVEAESRKIGRIFL
EEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEC
PDPLLFAIRKAPCIVVEASREARLEYLVRDYAYLGDDTARLQGLIEKLRGLQSNERIDNW
CCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
LALAQARALPALFGELVDHHYDPLYRRSQNGNYQGYAAAPRIVTDDLGPHNIPALAREIL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEECCCCEEECCCCCCCHHHHHHHHH
SMATNRD
HHHCCCC
>Mature Secondary Structure
MFQKGVAPQDAAPETMQKGVATVAQRGEFDEIIDARTPAEFAEDHIPGAINLPVLDDAQR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCC
ATVGTIYVQQSAFEARRIGAAMVAENIARHLYAHLQDKPKRWRPLVYCWRGGQRSGAFTT
CEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHH
WLRMIGWDACQLEGGYKRFRHVVIEELAQLAPAFDWRVVGGATGSAKTRILEALAAAGAQ
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCE
VVDLEGLAAHKGSVLGGLPDRPQPTQKGFETALHAVLSGLDPARPVFVEAESRKIGRIFL
EEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEC
PDPLLFAIRKAPCIVVEASREARLEYLVRDYAYLGDDTARLQGLIEKLRGLQSNERIDNW
CCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
LALAQARALPALFGELVDHHYDPLYRRSQNGNYQGYAAAPRIVTDDLGPHNIPALAREIL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEECCCCEEECCCCCCCHHHHHHHHH
SMATNRD
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]