Click here to switch to the map view.

The map label for this gene is mucD2 [H]

Identifier: 119897925

GI number: 119897925

Start: 1795023

End: 1796441

Strand: Direct

Name: mucD2 [H]

Synonym: azo1634

Alternate gene names: 119897925

Gene position: 1795023-1796441 (Clockwise)

Preceding gene: 119897924

Following gene: 119897926

Centisome position: 41.02

GC content: 67.94

Gene sequence:

>1419_bases
ATGAAGGGGCGGTTGCTGCGCTGGTTGAGCGCCTGTCTGTTGCTGCCGTTTGCGCCGGTGGGTCTCGCCGCAAGCCCGGC
CAACCTTCCCGATTTCACCGCCCTGGTCGAGCGCCAGGGCGCGGCGGTGGTCAACGTCAGTACTTCGCAGACCCGGCAGG
CGTCGCCGTCGGTACCGCGGGGACTCGACGAAAACGACCCGATGTTCGATTTCTTCCGCCGTTTCGTCCCGCGGCACCCC
CGTACGCCCGAACTCGATCCCGAGAACCGTTCGCTGGGCACCGGTTTCATCATCAGCGCCGACGGCTACATCCTGACGAA
TGCCCATGTGGTGGATGAGGCCGAGGAAATCCTCGTGCGGCTGGCTGACAAACGCGAGTTCGTCGCCACGGTGGTCGGGG
CGGATGCGCGTAGCGATGTCGCGTTGATCAAGATCGAAGCTGCCGGTCTGCCCAAGGTGGTGCTCGGAGACCCGGGGCGG
CTGAAGGTGGGCGAATGGGTCTTGGCGATCGGCTCGCCGTTCGGCTTTGAACAGACCGTGACCGCCGGCATTGTCAGCGC
CAAGGGACGCAGCCTGCCCGACGAGAACTTCGTGCCCTTCATCCAGACGGACGTGGCGATCAACCCGGGCAACTCCGGCG
GGCCGCTGTTCAATCTGCGTGGCGAGGTGGTCGGCATCAACTCACAGATCTACAGCCAGACCGGCGGCTTCATGGGGCTG
TCGTTCTCGATCCCGATCGACGTCGCGATGGATGTCCAGCAGCAGCTGCGCGCTCACGGCCGGGTGCAACGCGGCCGTAT
CGGTGTGGCCATCCAGGAGGTGTCGCGCGAGCTGGCGGAGAGCTTCAGCCTGCCGCGCGCGGCCGGTGCGTTGGTCAGCG
GTGTGGAGGCGGGCGGGCCGGCGGGCCAGGCGGGCGTGGAGCAAGGGGATGTCATCGTTCGTTTCGACGGCAAGAGCGTC
GAGGCCTCGACTGACCTGCCGCGCATCGTTTCCGCCAGCCGCCCTGGCGGTCGGGTCGCGATGCAGCTGTTCCGGCAAGG
CGCGCTGCGCGAAGTGACGGTCACGGTGGGCGAGTGGCGCGACAGCGCCGAGCCGGTGAAGAAGCCTGTGGTGGCGGCGC
GTGCCAGCACGATCAACAGCCTCGGCCTGCAGCTTGTTGCGCCCACGGGCGCGCAGCGGCGGGAACAAGGTGTGGAGCAC
GGGCTGCTGGTGGAGCGCGTCGCGGGGCCGGCCGCGCGGGCCGAACTGCGGCCGGGCGACCTCGTCCTGGCGCTGGTGAG
CAACGGCCGCCAGAGCGCGCTGCGCTCCCTGGAGGATTTCAGTCGCCAGCTCACCACCTTCAAGCCGGGTCAGCAGATCA
CCTTGCTGGTCAAGCGCGGCGAGGCCACCTCTTACGTCAGCGTCCGGGCCGAAAAATGA

Upstream 100 bases:

>100_bases
CCGGTCTCGGCCTGGCGGCCTTGCTGGTCCGGCTGGCCGGGCGCTGGTGGCCGTATTCGGCGGTACAGCTTGCCCGCCCC
GCTTGCAGCGGAGGGCAGTC

Downstream 100 bases:

>100_bases
GCGCGCGCGAGTTCACCGTGCTCAGCCGCGAGTGGTGCCACCTGTGCCATGACCTCGTTGCCGCGCTGGCGCCCCTGGCT
GAGGAGCTGGGGTGGAGCTA

Product: serine protease MucD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKGRLLRWLSACLLLPFAPVGLAASPANLPDFTALVERQGAAVVNVSTSQTRQASPSVPRGLDENDPMFDFFRRFVPRHP
RTPELDPENRSLGTGFIISADGYILTNAHVVDEAEEILVRLADKREFVATVVGADARSDVALIKIEAAGLPKVVLGDPGR
LKVGEWVLAIGSPFGFEQTVTAGIVSAKGRSLPDENFVPFIQTDVAINPGNSGGPLFNLRGEVVGINSQIYSQTGGFMGL
SFSIPIDVAMDVQQQLRAHGRVQRGRIGVAIQEVSRELAESFSLPRAAGALVSGVEAGGPAGQAGVEQGDVIVRFDGKSV
EASTDLPRIVSASRPGGRVAMQLFRQGALREVTVTVGEWRDSAEPVKKPVVAARASTINSLGLQLVAPTGAQRREQGVEH
GLLVERVAGPAARAELRPGDLVLALVSNGRQSALRSLEDFSRQLTTFKPGQQITLLVKRGEATSYVSVRAEK

Sequences:

>Translated_472_residues
MKGRLLRWLSACLLLPFAPVGLAASPANLPDFTALVERQGAAVVNVSTSQTRQASPSVPRGLDENDPMFDFFRRFVPRHP
RTPELDPENRSLGTGFIISADGYILTNAHVVDEAEEILVRLADKREFVATVVGADARSDVALIKIEAAGLPKVVLGDPGR
LKVGEWVLAIGSPFGFEQTVTAGIVSAKGRSLPDENFVPFIQTDVAINPGNSGGPLFNLRGEVVGINSQIYSQTGGFMGL
SFSIPIDVAMDVQQQLRAHGRVQRGRIGVAIQEVSRELAESFSLPRAAGALVSGVEAGGPAGQAGVEQGDVIVRFDGKSV
EASTDLPRIVSASRPGGRVAMQLFRQGALREVTVTVGEWRDSAEPVKKPVVAARASTINSLGLQLVAPTGAQRREQGVEH
GLLVERVAGPAARAELRPGDLVLALVSNGRQSALRSLEDFSRQLTTFKPGQQITLLVKRGEATSYVSVRAEK
>Mature_472_residues
MKGRLLRWLSACLLLPFAPVGLAASPANLPDFTALVERQGAAVVNVSTSQTRQASPSVPRGLDENDPMFDFFRRFVPRHP
RTPELDPENRSLGTGFIISADGYILTNAHVVDEAEEILVRLADKREFVATVVGADARSDVALIKIEAAGLPKVVLGDPGR
LKVGEWVLAIGSPFGFEQTVTAGIVSAKGRSLPDENFVPFIQTDVAINPGNSGGPLFNLRGEVVGINSQIYSQTGGFMGL
SFSIPIDVAMDVQQQLRAHGRVQRGRIGVAIQEVSRELAESFSLPRAAGALVSGVEAGGPAGQAGVEQGDVIVRFDGKSV
EASTDLPRIVSASRPGGRVAMQLFRQGALREVTVTVGEWRDSAEPVKKPVVAARASTINSLGLQLVAPTGAQRREQGVEH
GLLVERVAGPAARAELRPGDLVLALVSNGRQSALRSLEDFSRQLTTFKPGQQITLLVKRGEATSYVSVRAEK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=254, Percent_Identity=37.007874015748, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI24308541, Length=251, Percent_Identity=37.0517928286853, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI22129776, Length=264, Percent_Identity=35.9848484848485, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7019477, Length=273, Percent_Identity=35.8974358974359, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1789629, Length=454, Percent_Identity=34.5814977973568, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1786356, Length=381, Percent_Identity=37.7952755905512, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789630, Length=277, Percent_Identity=36.8231046931408, Blast_Score=171, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=35.4961832061069, Blast_Score=145, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 50254; Mature: 50254

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRLLRWLSACLLLPFAPVGLAASPANLPDFTALVERQGAAVVNVSTSQTRQASPSVPR
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
GLDENDPMFDFFRRFVPRHPRTPELDPENRSLGTGFIISADGYILTNAHVVDEAEEILVR
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHH
LADKREFVATVVGADARSDVALIKIEAAGLPKVVLGDPGRLKVGEWVLAIGSPFGFEQTV
HHCCHHEEHHEECCCCCCCEEEEEEECCCCCEEEECCCCCEECCCEEEEECCCCCCHHHH
TAGIVSAKGRSLPDENFVPFIQTDVAINPGNSGGPLFNLRGEVVGINSQIYSQTGGFMGL
HHHHHCCCCCCCCCCCCCCEEEECEEECCCCCCCCEEEECCCEEEECHHHHHCCCCEEEE
SFSIPIDVAMDVQQQLRAHGRVQRGRIGVAIQEVSRELAESFSLPRAAGALVSGVEAGGP
EEECCCHHHHHHHHHHHHCCCEECCEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
AGQAGVEQGDVIVRFDGKSVEASTDLPRIVSASRPGGRVAMQLFRQGALREVTVTVGEWR
CCCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCEEEEEEEECCC
DSAEPVKKPVVAARASTINSLGLQLVAPTGAQRREQGVEHGLLVERVAGPAARAELRPGD
CCCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCHHHHHHCCCHHHCCCCCCC
LVLALVSNGRQSALRSLEDFSRQLTTFKPGQQITLLVKRGEATSYVSVRAEK
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MKGRLLRWLSACLLLPFAPVGLAASPANLPDFTALVERQGAAVVNVSTSQTRQASPSVPR
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
GLDENDPMFDFFRRFVPRHPRTPELDPENRSLGTGFIISADGYILTNAHVVDEAEEILVR
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHH
LADKREFVATVVGADARSDVALIKIEAAGLPKVVLGDPGRLKVGEWVLAIGSPFGFEQTV
HHCCHHEEHHEECCCCCCCEEEEEEECCCCCEEEECCCCCEECCCEEEEECCCCCCHHHH
TAGIVSAKGRSLPDENFVPFIQTDVAINPGNSGGPLFNLRGEVVGINSQIYSQTGGFMGL
HHHHHCCCCCCCCCCCCCCEEEECEEECCCCCCCCEEEECCCEEEECHHHHHCCCCEEEE
SFSIPIDVAMDVQQQLRAHGRVQRGRIGVAIQEVSRELAESFSLPRAAGALVSGVEAGGP
EEECCCHHHHHHHHHHHHCCCEECCEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
AGQAGVEQGDVIVRFDGKSVEASTDLPRIVSASRPGGRVAMQLFRQGALREVTVTVGEWR
CCCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCEEEEEEEECCC
DSAEPVKKPVVAARASTINSLGLQLVAPTGAQRREQGVEHGLLVERVAGPAARAELRPGD
CCCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCCCHHHHHHCCCHHHCCCCCCC
LVLALVSNGRQSALRSLEDFSRQLTTFKPGQQITLLVKRGEATSYVSVRAEK
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]