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The map label for this gene is rseB [H]

Identifier: 119897923

GI number: 119897923

Start: 1793615

End: 1794586

Strand: Direct

Name: rseB [H]

Synonym: azo1632

Alternate gene names: 119897923

Gene position: 1793615-1794586 (Clockwise)

Preceding gene: 119897922

Following gene: 119897924

Centisome position: 40.99

GC content: 65.23

Gene sequence:

>972_bases
ATGAAACGATGGTTTGCGGCGGCGGGGCTTTGTCTGGCCCTGCTCCCGGGGGCGGCTCAGGCCGAGGCGCCTTCCGACCC
GCTCGGCTGGCTGAACAGGATCGCCTCGGCTGGGCAGCGGCTGAACTACGTCGGCACCTTCGTTTACCAGTCCGGCAAGC
ACTTCGAAACGTCGAGAATCGCCCATCGGGTGGATTCCTCCGGCGAGTACGAACGACTGGAAGTGCTCGACGGCAGCCCG
CGCGAGGTCATCCGCAACAGTGGCGAGGTCCGCTGCGTGTTGCCGGACCAGAAGACCGTGATCATCGATCGCCCCGGTGG
TCGGCGTGCATTTCCGGCCCGTCTGCCTTCGTCGTTCTCGAACCTGGGGGAAAGCTACCGGATCCGCAAGGGCGAGGTGC
ATCGGATTGCGGGTCTCGAGGCGCAGGCCATCCTTCTGGAACCCAAGGATGATCTCCGCTACGGCCATGCGCTGTGGGCC
GAGGTCCAGTCGGGCCTGTTGCTGAAATCCCGTCTGCTGGACGAGCGCGGCGAAATCATCGAGCAGTTTGTGTTCAACGA
CGTGCGCATCGGCGGCAACATCAGTCCGGATCTGCTCAAACCGCGTTATGTCAGCACCGACGACTGGCGTGTCGTCCAGG
CGCGCGGAAGCGACGTCCCGCGCAGCGAAGCCGGCTGGGCACTGCGCACCCCCTTGCCCGGCTTCACGCTGCAGTCGGTG
GTCAAGCGTCCTCTTGGTCGGGAGCGCGGCGATGTCGTGCAGATGGTCTATGGCGACGGCCTTGCGTCGATTTCGCTCTT
CATCGAGCCCGCCGCGTCCGACAGCGCGGCAGCCGTGCTCGGTGCGCAGACCAGCGGGGCGATCAACATCTACAAACGGG
TAGCAGGCGCCCACCTGATCACCGTGTTGGGCGAGGTCCCGATGCGTACGATCCAGCGCCTCGGCGACGGTATGGAGTTC
GTCGGTCAGTGA

Upstream 100 bases:

>100_bases
AATACGTGTTCGCTCACCAGTCCATGACGGCCGGCGGTCCGATTCCCGGCGCCGTTCAGTATGTCAGGACGGTCACCGAG
ACCCAGCAGGGCGCAGGACA

Downstream 100 bases:

>100_bases
TGCGCGCACCGGCTGAGGTGGTCGCGGTCCGTGGTGGATCCGCGTGGGTTAAGGTCACACGCACCGGCGGTTGCGGACGG
TGCGACGAGCCAGGCGGCTG

Product: putative sigma factor regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKRWFAAAGLCLALLPGAAQAEAPSDPLGWLNRIASAGQRLNYVGTFVYQSGKHFETSRIAHRVDSSGEYERLEVLDGSP
REVIRNSGEVRCVLPDQKTVIIDRPGGRRAFPARLPSSFSNLGESYRIRKGEVHRIAGLEAQAILLEPKDDLRYGHALWA
EVQSGLLLKSRLLDERGEIIEQFVFNDVRIGGNISPDLLKPRYVSTDDWRVVQARGSDVPRSEAGWALRTPLPGFTLQSV
VKRPLGRERGDVVQMVYGDGLASISLFIEPAASDSAAAVLGAQTSGAINIYKRVAGAHLITVLGEVPMRTIQRLGDGMEF
VGQ

Sequences:

>Translated_323_residues
MKRWFAAAGLCLALLPGAAQAEAPSDPLGWLNRIASAGQRLNYVGTFVYQSGKHFETSRIAHRVDSSGEYERLEVLDGSP
REVIRNSGEVRCVLPDQKTVIIDRPGGRRAFPARLPSSFSNLGESYRIRKGEVHRIAGLEAQAILLEPKDDLRYGHALWA
EVQSGLLLKSRLLDERGEIIEQFVFNDVRIGGNISPDLLKPRYVSTDDWRVVQARGSDVPRSEAGWALRTPLPGFTLQSV
VKRPLGRERGDVVQMVYGDGLASISLFIEPAASDSAAAVLGAQTSGAINIYKRVAGAHLITVLGEVPMRTIQRLGDGMEF
VGQ
>Mature_323_residues
MKRWFAAAGLCLALLPGAAQAEAPSDPLGWLNRIASAGQRLNYVGTFVYQSGKHFETSRIAHRVDSSGEYERLEVLDGSP
REVIRNSGEVRCVLPDQKTVIIDRPGGRRAFPARLPSSFSNLGESYRIRKGEVHRIAGLEAQAILLEPKDDLRYGHALWA
EVQSGLLLKSRLLDERGEIIEQFVFNDVRIGGNISPDLLKPRYVSTDDWRVVQARGSDVPRSEAGWALRTPLPGFTLQSV
VKRPLGRERGDVVQMVYGDGLASISLFIEPAASDSAAAVLGAQTSGAINIYKRVAGAHLITVLGEVPMRTIQRLGDGMEF
VGQ

Specific function: Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate- producing form. Inactivation of mucB causes conversion to mucoidy [H]

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family [H]

Homologues:

Organism=Escherichia coli, GI1788924, Length=325, Percent_Identity=26.4615384615385, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005588 [H]

Pfam domain/function: PF03888 MucB_RseB [H]

EC number: NA

Molecular weight: Translated: 35341; Mature: 35341

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRWFAAAGLCLALLPGAAQAEAPSDPLGWLNRIASAGQRLNYVGTFVYQSGKHFETSRI
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCHHHHH
AHRVDSSGEYERLEVLDGSPREVIRNSGEVRCVLPDQKTVIIDRPGGRRAFPARLPSSFS
HHHCCCCCCEEEEEECCCCHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCCHHHH
NLGESYRIRKGEVHRIAGLEAQAILLEPKDDLRYGHALWAEVQSGLLLKSRLLDERGEII
HCCHHCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EQFVFNDVRIGGNISPDLLKPRYVSTDDWRVVQARGSDVPRSEAGWALRTPLPGFTLQSV
HHHHHHCEEECCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHH
VKRPLGRERGDVVQMVYGDGLASISLFIEPAASDSAAAVLGAQTSGAINIYKRVAGAHLI
HHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
TVLGEVPMRTIQRLGDGMEFVGQ
HHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MKRWFAAAGLCLALLPGAAQAEAPSDPLGWLNRIASAGQRLNYVGTFVYQSGKHFETSRI
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCHHHHH
AHRVDSSGEYERLEVLDGSPREVIRNSGEVRCVLPDQKTVIIDRPGGRRAFPARLPSSFS
HHHCCCCCCEEEEEECCCCHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCCHHHH
NLGESYRIRKGEVHRIAGLEAQAILLEPKDDLRYGHALWAEVQSGLLLKSRLLDERGEII
HCCHHCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EQFVFNDVRIGGNISPDLLKPRYVSTDDWRVVQARGSDVPRSEAGWALRTPLPGFTLQSV
HHHHHHCEEECCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHH
VKRPLGRERGDVVQMVYGDGLASISLFIEPAASDSAAAVLGAQTSGAINIYKRVAGAHLI
HHHHCCCCCCCEEEEEECCCEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
TVLGEVPMRTIQRLGDGMEFVGQ
HHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412698; 8378309; 8444793; 10984043 [H]