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The map label for this gene is algU [H]

Identifier: 119897921

GI number: 119897921

Start: 1792464

End: 1793063

Strand: Direct

Name: algU [H]

Synonym: azo1630

Alternate gene names: 119897921

Gene position: 1792464-1793063 (Clockwise)

Preceding gene: 119897919

Following gene: 119897922

Centisome position: 40.96

GC content: 62.0

Gene sequence:

>600_bases
ATGAGCGATCGCGAAATCGATCAGCAACTTGTCGAACGCGTGCAGCGTGGCGACAAGCAGGCCTTCGGCTTGTTGGTTTC
CAAATACCAGCGCAAGCTGCATCGGCTGCTTTCGAGGCTGATCCGTGATCCGGCCGAGGTCGAGGACGTGGCGCAGGAGA
CCTTCATCAAGGCCTACCGTGCGCTCGGTTCCTTTCGCGGGGACAGCGCCTTCTACACCTGGCTCTACCGCATCGGAATC
AACACGGCGAAGAATTACCTCGTGTCCCAGGGGCGGCGTGCGCCGACCTCCACGGGGTTCGACTCGGAGGAAGCTGAAAC
TTTCGAGGACGGGGATCAGCTGCGCGACATCAACACGCCGGAGCGCTTGATGATGACGCAGCAGATCGGGGAAACGGTCG
ACGCGGCGATGGCGGGGCTTCCCGAAGAATTGCGGACGGCGATCATGCTGCGCGAGTTCGAGGGGCTGAGCTACGAAGAG
ATCGCCAACATCATGGATTGCCCGATAGGGACGGTGCGGTCGCGGATCTTCCGTGCCCGCGAAGCGATTGCAGAACGGTT
GCGCCCGCTGCTCGACACGGCGCCGGACAAACGTTGGTAG

Upstream 100 bases:

>100_bases
TGTTTCGGTCTTTCCACGTATCTTCGACTTTGGCGGGCGGACAGGCGGTCGCTTATACTTGGGCGCTTTTGTTTCCTTAC
TCAAGCAGAACGACCATCTC

Downstream 100 bases:

>100_bases
GTGGCAGGAATGAAGGAAAAACTCTCGGCTTTGCTCGACGGCGTTCTCGATGAACATGCCGTGGCTCCCACGCTGAACGG
CTTGCGTAGCGACAGCGCGC

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSDREIDQQLVERVQRGDKQAFGLLVSKYQRKLHRLLSRLIRDPAEVEDVAQETFIKAYRALGSFRGDSAFYTWLYRIGI
NTAKNYLVSQGRRAPTSTGFDSEEAETFEDGDQLRDINTPERLMMTQQIGETVDAAMAGLPEELRTAIMLREFEGLSYEE
IANIMDCPIGTVRSRIFRAREAIAERLRPLLDTAPDKRW

Sequences:

>Translated_199_residues
MSDREIDQQLVERVQRGDKQAFGLLVSKYQRKLHRLLSRLIRDPAEVEDVAQETFIKAYRALGSFRGDSAFYTWLYRIGI
NTAKNYLVSQGRRAPTSTGFDSEEAETFEDGDQLRDINTPERLMMTQQIGETVDAAMAGLPEELRTAIMLREFEGLSYEE
IANIMDCPIGTVRSRIFRAREAIAERLRPLLDTAPDKRW
>Mature_198_residues
SDREIDQQLVERVQRGDKQAFGLLVSKYQRKLHRLLSRLIRDPAEVEDVAQETFIKAYRALGSFRGDSAFYTWLYRIGIN
TAKNYLVSQGRRAPTSTGFDSEEAETFEDGDQLRDINTPERLMMTQQIGETVDAAMAGLPEELRTAIMLREFEGLSYEEI
ANIMDCPIGTVRSRIFRAREAIAERLRPLLDTAPDKRW

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=191, Percent_Identity=61.7801047120419, Blast_Score=239, Evalue=7e-65,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22880; Mature: 22749

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDREIDQQLVERVQRGDKQAFGLLVSKYQRKLHRLLSRLIRDPAEVEDVAQETFIKAYR
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ALGSFRGDSAFYTWLYRIGINTAKNYLVSQGRRAPTSTGFDSEEAETFEDGDQLRDINTP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
ERLMMTQQIGETVDAAMAGLPEELRTAIMLREFEGLSYEEIANIMDCPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
EAIAERLRPLLDTAPDKRW
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDREIDQQLVERVQRGDKQAFGLLVSKYQRKLHRLLSRLIRDPAEVEDVAQETFIKAYR
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ALGSFRGDSAFYTWLYRIGINTAKNYLVSQGRRAPTSTGFDSEEAETFEDGDQLRDINTP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
ERLMMTQQIGETVDAAMAGLPEELRTAIMLREFEGLSYEEIANIMDCPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
EAIAERLRPLLDTAPDKRW
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]