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The map label for this gene is fabD [H]

Identifier: 119897915

GI number: 119897915

Start: 1786843

End: 1787772

Strand: Direct

Name: fabD [H]

Synonym: azo1624

Alternate gene names: 119897915

Gene position: 1786843-1787772 (Clockwise)

Preceding gene: 119897914

Following gene: 119897916

Centisome position: 40.83

GC content: 67.42

Gene sequence:

>930_bases
ATGGCTTTTGCGCTGGTTTTTCCAGGCCAGGGTTCGCAGTCCGTCGCGATGATGGACGCGTATGGCGAATCCGCGGTGAT
CCGCGACACTTTTGCCGAGGCCTCTGCGGCGCTGGGTGAAGATTTGTGGCAGATGGTGTGCGAAGGACCGGCGGAGCGCC
TGGCGCTCACGGTGAATACGCAACCTCTGATGCTGACTGCCGGCGTGGCGGTGTATCGCGCCTGGCTTGCGGCCGGCGGT
CCCAAACCGGCGATCGTCGCCGGTCACAGCCTCGGCGAGTATGCGGCGCTGGTGGCTGCTGGCGCACTGGCGTTTGCCGA
CGCTGTGCCGCTGGTGCGGTTGCGCGCTCAGGCCATGCAGGAAGCCGTGCCGGCGGGCGAGGGCGCGATGGCCGCCCTGC
TCGGGCTGGAGGCGGACGCAGTGCGGGAGGCTTGTGCCGAAGCGGCGCAAGGCGAGGTCGTCGAGGCGGCCAACCTGAAT
GCGCCGGGGCAGATCGTCATCGCCGGGGCCAAGGCTGCCGTCGAGCGTGCGATCGAGGTCGCCAAGGGCAAGGGCGCAAA
GCGCGCGGTGTTGCTGCCGGTTTCGGCCCCGTTCCACTGTGCCTTGATGAAGCCGGCCGCGGAGCGGTTGGCGGAGCGTC
TGGCAGGTCTCGAAATCCGCACCCCCGAGATCGACGTGCTGAACAACGTCGATGTTGCGGTGTACGCGGAGCCGGACCGT
ATCCGTGACGCGCTGGTGCGGCAGGCGTTTTCGCCGGTGCGCTGGATCGAATCCGTGCAGGAAATGGCCCGTCGCGGAAT
GACCCATGTCGTCGAATGCGGGCCCGGCAAGGTGCTCGCCGGCATGACCAAGCGCATCGCGAAGGACATCGAAGGCGGCT
CGGCACACGACGCCGCGAGTCTGGAACAATCGATTGCGGCAGTGAGGTAA

Upstream 100 bases:

>100_bases
CCCCGGGCAGCGCGTCGTGGTCGAGGGTGTAGGCGGCGGGTTCACCTGGGGCGCAGCCCTGATCGACTTCTGATTTCTTC
CGATAGACCTTGGAGAGATG

Downstream 100 bases:

>100_bases
GAATGAGTTTTTCGCTGGAAGGACAGATCGCGCTGGTTACCGGCGCCTCGCGCGGGATCGGTCGCGCGGTAGCGATGGAA
CTGGCCCGGCTCGGCGCCGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAFALVFPGQGSQSVAMMDAYGESAVIRDTFAEASAALGEDLWQMVCEGPAERLALTVNTQPLMLTAGVAVYRAWLAAGG
PKPAIVAGHSLGEYAALVAAGALAFADAVPLVRLRAQAMQEAVPAGEGAMAALLGLEADAVREACAEAAQGEVVEAANLN
APGQIVIAGAKAAVERAIEVAKGKGAKRAVLLPVSAPFHCALMKPAAERLAERLAGLEIRTPEIDVLNNVDVAVYAEPDR
IRDALVRQAFSPVRWIESVQEMARRGMTHVVECGPGKVLAGMTKRIAKDIEGGSAHDAASLEQSIAAVR

Sequences:

>Translated_309_residues
MAFALVFPGQGSQSVAMMDAYGESAVIRDTFAEASAALGEDLWQMVCEGPAERLALTVNTQPLMLTAGVAVYRAWLAAGG
PKPAIVAGHSLGEYAALVAAGALAFADAVPLVRLRAQAMQEAVPAGEGAMAALLGLEADAVREACAEAAQGEVVEAANLN
APGQIVIAGAKAAVERAIEVAKGKGAKRAVLLPVSAPFHCALMKPAAERLAERLAGLEIRTPEIDVLNNVDVAVYAEPDR
IRDALVRQAFSPVRWIESVQEMARRGMTHVVECGPGKVLAGMTKRIAKDIEGGSAHDAASLEQSIAAVR
>Mature_308_residues
AFALVFPGQGSQSVAMMDAYGESAVIRDTFAEASAALGEDLWQMVCEGPAERLALTVNTQPLMLTAGVAVYRAWLAAGGP
KPAIVAGHSLGEYAALVAAGALAFADAVPLVRLRAQAMQEAVPAGEGAMAALLGLEADAVREACAEAAQGEVVEAANLNA
PGQIVIAGAKAAVERAIEVAKGKGAKRAVLLPVSAPFHCALMKPAAERLAERLAGLEIRTPEIDVLNNVDVAVYAEPDRI
RDALVRQAFSPVRWIESVQEMARRGMTHVVECGPGKVLAGMTKRIAKDIEGGSAHDAASLEQSIAAVR

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=322, Percent_Identity=32.6086956521739, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=38.5321100917431, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787334, Length=300, Percent_Identity=55.3333333333333, Blast_Score=315, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=32.6530612244898, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=299, Percent_Identity=29.0969899665552, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24665753, Length=299, Percent_Identity=35.4515050167224, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32037; Mature: 31906

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFALVFPGQGSQSVAMMDAYGESAVIRDTFAEASAALGEDLWQMVCEGPAERLALTVNT
CEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECC
QPLMLTAGVAVYRAWLAAGGPKPAIVAGHSLGEYAALVAAGALAFADAVPLVRLRAQAMQ
CCEEEHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPAGEGAMAALLGLEADAVREACAEAAQGEVVEAANLNAPGQIVIAGAKAAVERAIEV
HHCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECHHHHHHHHHHH
AKGKGAKRAVLLPVSAPFHCALMKPAAERLAERLAGLEIRTPEIDVLNNVDVAVYAEPDR
HCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEECCCCEEEECCCCEEEEECHHH
IRDALVRQAFSPVRWIESVQEMARRGMTHVVECGPGKVLAGMTKRIAKDIEGGSAHDAAS
HHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHH
LEQSIAAVR
HHHHHHHCC
>Mature Secondary Structure 
AFALVFPGQGSQSVAMMDAYGESAVIRDTFAEASAALGEDLWQMVCEGPAERLALTVNT
EEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECC
QPLMLTAGVAVYRAWLAAGGPKPAIVAGHSLGEYAALVAAGALAFADAVPLVRLRAQAMQ
CCEEEHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPAGEGAMAALLGLEADAVREACAEAAQGEVVEAANLNAPGQIVIAGAKAAVERAIEV
HHCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECHHHHHHHHHHH
AKGKGAKRAVLLPVSAPFHCALMKPAAERLAERLAGLEIRTPEIDVLNNVDVAVYAEPDR
HCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEECCCCEEEECCCCEEEEECHHH
IRDALVRQAFSPVRWIESVQEMARRGMTHVVECGPGKVLAGMTKRIAKDIEGGSAHDAAS
HHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHH
LEQSIAAVR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]