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The map label for this gene is hipO2 [H]

Identifier: 119897896

GI number: 119897896

Start: 1764095

End: 1765264

Strand: Direct

Name: hipO2 [H]

Synonym: azo1605

Alternate gene names: 119897896

Gene position: 1764095-1765264 (Clockwise)

Preceding gene: 119897890

Following gene: 119897897

Centisome position: 40.31

GC content: 70.43

Gene sequence:

>1170_bases
ATGAGCATCATCGACATCGTCAGTCCGCGTCTTTACAACCTGAAGGCGATCCGCCGCGACCTTCACGCCCATCCGGAACT
CGCCTTCGCCGAACACCGCACTGCCGACGTCGTCGCCCGCCACCTGACGTCGCTCGGGCTGGAGGTGCATCGCGGCCTTG
GCGGCACCGGCGTGGTCGGCGTCGTGCGCGGTGGCCGCGGCCTGCGTGCGATCGGCCTGCGCGCGGACATGGACGCGCTG
CCGATTACCGAGCGTAACACCTTCGCCCACCGCTCCACTGTGGAGGCCTGCATGCATGCCTGCGGGCATGACGGCCACAC
GACGATGCTGCTCGGCGCTGCCGAGGTCCTGGCCGCGCGGCCGGATTTCGACGGCACGGTGTACCTGATCTTCCAGCCTG
CCGAAGAGGGTGAGGGCGGCGCGCGGGCGATGATCGAGGACGGCCTGTTCGACCGTTTTCCGATGGAGTCGGTATTCGGC
ATGCACAACTGGCCCGGCATGGCGGCCGGCAGCTTTGCGGTGCACGCCGGGCCGGTGATGGCGAGCGCAGACCGCTTCGA
CATCACGGTCCGCGGCCATGGCGCCCACGCCGCGATGCCGCACCTGGGCACCGACCCGGTGACCGCGGCCGCGGCGCTGG
TGCAGGCGGTGCAGACCATCGTCTCGCGCAACCTCGACCCGGTGGTGTCGGCGGTGGTGTCCATCACCCAGTTCCATGCG
GGCGAGGCCTACAACGCCATTCCCGACCGCGCCGAGCTGGCCGGCACCGTGCGGGCCTTCTCGGAACAGGTGCAGGAGGC
GGTGGAAGCGCGCCTGCGCACGCTGTGCGAGGGCACCGCGGCGGCGTTCGGCGTGGAGGTCGAATTCGAATACCGGCGCG
GCTATCCGCCGACGGTCAACACCGCCGCCGAGGCCGCGCTGTGCGCCGACGCCGCGCGGGCGGTGGCGGGAGAAGGCGCG
GTGACTACCGCCGCGCCACCCAGCATGGGGGCGGAGGACTTCGCCTTCTTCCTGCAGAAGAAGCCGGGCGCCTATATCTG
GATCGGCAACGGCCCGGGCGAGGGCGGCTGCACGCTGCACAACCCGCATTACGACTTCAACGACGACATCTTGCCGGCGG
GCATCGGCTACTGGGTGGAGCTGGTGCGGCGTCTGCTGCCGGCGCGCTGA

Upstream 100 bases:

>100_bases
CGCACCGGGGAGCGGGCGGCGCACAGTCCTTCGGGTCCTGTACTACACTCGGCCGTTCCCGCCGTCCGTCTTCCGCCGCC
TTTCCGGCCTGGGTGCAACC

Downstream 100 bases:

>100_bases
GGACCCTTCATGAACACGCTCCGGCTCGCTTTCCGCATGATGCTGCGCGACCTGCGCGCGGGCGAATTGCACCTGCTGGG
GCTGGCGATCGTGGTCGCGG

Product: hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSIIDIVSPRLYNLKAIRRDLHAHPELAFAEHRTADVVARHLTSLGLEVHRGLGGTGVVGVVRGGRGLRAIGLRADMDAL
PITERNTFAHRSTVEACMHACGHDGHTTMLLGAAEVLAARPDFDGTVYLIFQPAEEGEGGARAMIEDGLFDRFPMESVFG
MHNWPGMAAGSFAVHAGPVMASADRFDITVRGHGAHAAMPHLGTDPVTAAAALVQAVQTIVSRNLDPVVSAVVSITQFHA
GEAYNAIPDRAELAGTVRAFSEQVQEAVEARLRTLCEGTAAAFGVEVEFEYRRGYPPTVNTAAEAALCADAARAVAGEGA
VTTAAPPSMGAEDFAFFLQKKPGAYIWIGNGPGEGGCTLHNPHYDFNDDILPAGIGYWVELVRRLLPAR

Sequences:

>Translated_389_residues
MSIIDIVSPRLYNLKAIRRDLHAHPELAFAEHRTADVVARHLTSLGLEVHRGLGGTGVVGVVRGGRGLRAIGLRADMDAL
PITERNTFAHRSTVEACMHACGHDGHTTMLLGAAEVLAARPDFDGTVYLIFQPAEEGEGGARAMIEDGLFDRFPMESVFG
MHNWPGMAAGSFAVHAGPVMASADRFDITVRGHGAHAAMPHLGTDPVTAAAALVQAVQTIVSRNLDPVVSAVVSITQFHA
GEAYNAIPDRAELAGTVRAFSEQVQEAVEARLRTLCEGTAAAFGVEVEFEYRRGYPPTVNTAAEAALCADAARAVAGEGA
VTTAAPPSMGAEDFAFFLQKKPGAYIWIGNGPGEGGCTLHNPHYDFNDDILPAGIGYWVELVRRLLPAR
>Mature_388_residues
SIIDIVSPRLYNLKAIRRDLHAHPELAFAEHRTADVVARHLTSLGLEVHRGLGGTGVVGVVRGGRGLRAIGLRADMDALP
ITERNTFAHRSTVEACMHACGHDGHTTMLLGAAEVLAARPDFDGTVYLIFQPAEEGEGGARAMIEDGLFDRFPMESVFGM
HNWPGMAAGSFAVHAGPVMASADRFDITVRGHGAHAAMPHLGTDPVTAAAALVQAVQTIVSRNLDPVVSAVVSITQFHAG
EAYNAIPDRAELAGTVRAFSEQVQEAVEARLRTLCEGTAAAFGVEVEFEYRRGYPPTVNTAAEAALCADAARAVAGEGAV
TTAAPPSMGAEDFAFFLQKKPGAYIWIGNGPGEGGCTLHNPHYDFNDDILPAGIGYWVELVRRLLPAR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=423, Percent_Identity=28.1323877068558, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41304; Mature: 41173

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIDIVSPRLYNLKAIRRDLHAHPELAFAEHRTADVVARHLTSLGLEVHRGLGGTGVVG
CCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VVRGGRGLRAIGLRADMDALPITERNTFAHRSTVEACMHACGHDGHTTMLLGAAEVLAAR
EEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCC
PDFDGTVYLIFQPAEEGEGGARAMIEDGLFDRFPMESVFGMHNWPGMAAGSFAVHAGPVM
CCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCE
ASADRFDITVRGHGAHAAMPHLGTDPVTAAAALVQAVQTIVSRNLDPVVSAVVSITQFHA
ECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GEAYNAIPDRAELAGTVRAFSEQVQEAVEARLRTLCEGTAAAFGVEVEFEYRRGYPPTVN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCCCC
TAAEAALCADAARAVAGEGAVTTAAPPSMGAEDFAFFLQKKPGAYIWIGNGPGEGGCTLH
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEC
NPHYDFNDDILPAGIGYWVELVRRLLPAR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIIDIVSPRLYNLKAIRRDLHAHPELAFAEHRTADVVARHLTSLGLEVHRGLGGTGVVG
CCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VVRGGRGLRAIGLRADMDALPITERNTFAHRSTVEACMHACGHDGHTTMLLGAAEVLAAR
EEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCC
PDFDGTVYLIFQPAEEGEGGARAMIEDGLFDRFPMESVFGMHNWPGMAAGSFAVHAGPVM
CCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCE
ASADRFDITVRGHGAHAAMPHLGTDPVTAAAALVQAVQTIVSRNLDPVVSAVVSITQFHA
ECCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GEAYNAIPDRAELAGTVRAFSEQVQEAVEARLRTLCEGTAAAFGVEVEFEYRRGYPPTVN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCCCC
TAAEAALCADAARAVAGEGAVTTAAPPSMGAEDFAFFLQKKPGAYIWIGNGPGEGGCTLH
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCEEC
NPHYDFNDDILPAGIGYWVELVRRLLPAR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]